New research directly measures human muscle contractile properties, revealing that extrapolating animal data to humans based on size is inaccurate. The study finds that human muscle fiber-specific tension is 24% smaller than traditionally used in small mammals.
Researchers discovered unique 'pulvinar slits' in the cell walls of cortical motor cells in legume pulvini, which enable flexible control of leaf movement. The slits allowed for anisotropic extension and contraction, facilitating plant cell wall flexing in response to osmotic changes.
Two novel genetically defined mouse models replicate two subtypes of human multiple myeloma, revealing the interaction of genetic aberrations as a key factor in development. The models will aid in identifying specific therapeutic strategies for individualized treatment.
A recent study analyzed data from 41,516 refugees and 207,729 Swedish-born individuals to investigate the impact of mental and somatic illnesses on labor market integration. The study found that multimorbidity poses a significant risk for unemployment among young refugees, highlighting the need for targeted public health actions.
A 16-year analysis of Brazilian research funding reveals stagnant funding for neglected tropical diseases, including chikungunya, Chagas disease, schistosomiasis, and malaria. Systematic underfunding is observed even among these diseases, which are considered neglected tropical diseases.
Astronomers at UC Irvine have found that terminator zones on distant exoplanets could be prime sites for liquid water and potentially harbor life. The study suggests that these regions offer a unique climate stability, making them more promising than previously thought.
A national US study found trust in government cancer information plummeted by 53% among non-Hispanic Black people during the pandemic. Meanwhile, trust in doctors remained high, highlighting the need for effective communication and access to healthcare services.
A Kaiser Permanente study found that receiving Paxlovid within 5 days of COVID-19 symptoms significantly reduced the risk of hospital admission or death. The medication was effective in people with prior immunity and all ages.
A recent study found that people with disabilities experienced increased household employment loss and financial hardship during the initial COVID-19 pandemic. The findings suggest a disproportionate impact on racial and ethnic minority respondents, highlighting the need for targeted policies and resources to address these issues.
Researchers at CZ Biohub SF and UCSF create high-resolution map of human immune response to P. falciparum, revealing why durable malaria vaccines have been hard to come by. The study uses sophisticated method to analyze antibodies' binding patterns to parasite proteins, offering insight into how malaria evades the immune system.
Researchers from Université libre de Bruxelles and French National Centre for Scientific Research show that processes violating causal inequalities can be realised in standard quantum mechanics using delocalised variables. This finding has far-reaching implications for our understanding of causality in physics.
A new study by Dr Stuart Fox found that childhood volunteering increases interest in politics and attachment to community, leading to a greater propensity to view voting as a civic duty. However, the effect was limited, with most children from disengaged households already likely to vote in adulthood.
Researchers discover a mechanism for shaping tissue boundaries during Arabidopsis root vascular tissue development. Positionally biased cell proliferation generates anisotropic compressive stress field, symmetrizing the boundary between xylem and procambium cells.
A new tool can accurately forecast the prevalence of individuals with insufficient access to food, allowing for timely responses. The tool was developed using data from six countries and achieved high accuracy rates, particularly in Yemen and Syria.
Researchers have developed a new type of OLED display that uses strong coupling of light and matter to improve color saturation and brightness. The displays, known as polariton-based OLEDs, achieve this without compromising efficiency or viewing angle dependency.
Researchers discovered a novel waste removal factor, CDNF, that treats brain haemorrhage by accelerating lesion resolution, reducing brain swelling, and improving functional outcomes. The treatment also alleviates cell stress and promotes scavenging by immune cells, leading to better recovery.
A study found that preterm infants do not habituate to repeated pain, unlike full-term infants. This lack of adaptation may affect their brain development and increase vulnerability to pain. The researchers' findings suggest that the ability to adapt to pain might develop during the third trimester of pregnancy.
Scientists have developed a way to modify OLED emission spectra without sacrificing efficiency, enabling greater colour saturation and brightness. The new technology utilises strong coupling between light and matter to create hybrid polariton particles, improving colour purity and stability.
A new method to cure HIV using umbilical cord blood stem cells has yielded long-term successful results for a middle-aged mixed-race woman with leukemia and HIV. The approach broadens the opportunities for people of diverse ancestry to attain cures.
A recent study published in JAMA demonstrates the effectiveness of a minimally invasive procedure called renal denervation (RDN) to treat uncontrolled hypertension. RDN uses ultrasound energy delivered through a small balloon to denervate the renal artery, reducing sympathetic nerve activity and decreasing blood pressure.
Researchers at German Cancer Research Center have developed a marker that predicts which patients with acute myeloid leukemia (AML) will respond to the new therapy. The marker, known as the MAC score, measures the ratio of specific proteins in leukemia stem cells and can be used to determine treatment success.
A Swedish study suggests that elite male footballers are 1.5 times more likely to develop neurodegenerative disease, including Alzheimer's and Parkinson's disease, compared to population controls. Football players had a higher risk of dementia due to head trauma exposure, with goalkeepers showing no significant increase in risk.
Researchers observed a shift towards earlier springtime flowering in common morning glory plants as temperatures rose, with increased investment in floral rewards such as nectar and pollen. The study used the 'resurrection' approach to examine changes in floral morphology over nine years, revealing significant increases in flower size ...
This study found that lncRNA TARL promotes the host's innate immune response by competing with TAK1 mRNA to bind miR-2188-3p, thereby helping fish resist Vibrio infection. Down-regulation of TAK1 expression improved bacterial escape efficiency.
A new study published in Blood Advances found that the average life expectancy of publicly insured individuals with sickle cell disease is roughly 52.6 years, which is significantly lower than the overall US life expectancy of 73.5 years for men and 79.3 years for women. The study also revealed worse survival outcomes among those insur...
Researchers at Tokyo University of Science used computer simulations to clarify why L-alanine was preferred over D-alanine during primordial RNA aminoacylation reactions. The study revealed that L-amino acid had more electrostatic stability in its transition state, providing a plausible reason for the selective aminoacylation.
A recent genomic study identifies two genetically distinct Ashaninka subgroups, suggesting a complex history of interactions with neighboring populations. The research also hints at a possible migration from southeastern South America or the Southern Cone, shedding new light on the genetic origins of this Indigenous group.
Researchers investigated point mutations in the androgen receptor, which affect its function and lead to diseases such as prostate cancer. The study found that these mutations deregulate posttranscriptional modifications, causing functional changes and pathologies.
Researchers developed StarCrete, a cosmic concrete made from Martian dust, potato starch, and salt, which is twice as strong as regular concrete. The material's compressive strength reaches 72 MPa, making it suitable for space construction.
Research from the University of Waterloo found that employees often feel pressure to continue working despite wanting a break due to fear of falling behind. The study suggests that promoting employee well-being by addressing unpleasant work conditions can help reduce the need for breaks.
The discovery of Hala Sultan Tekke, a Cypriot village with extensive copper production and trade hubs, reveals that Cyprus was the largest copper producer around the Mediterranean during the Bronze Age. The city's well-protected harbour and central location facilitated lively trade with neighbouring regions.
Researchers from POSTECH and University of Ulsan developed an omnidirectionally stretchable pressure sensor mimicking the structure and function of a crocodile's sensory organ. The sensor maintains sensitivity to pressure even when subjected to significant deformation, enabling its use in various wearable devices.
Researchers found that Greenlandic glacial rock flour can capture large amounts of CO2 through enhanced weathering, improving crop yields by up to 24% in Danish fields. The fine powder also acts as a natural fertilizer, providing a wider array of nutrients than commercial organic fertilizers.
A recent study found that dog owners are more likely to experience sleep disorders than non-dog owners. Cat ownership was also linked to higher odds of leg jerks during the night. The research suggests that pets may disrupt their owner's sleep due to increased activity at night, particularly with cats.
Researchers developed HIV-1-infection models in human microglia cell cultures to investigate the insertion of the HIV-1 genome. They discovered a correlation between a cellular chromatin factor and the sleeping virus phenotype, linking viral integration to topologically associated domains.
Researchers have designed a new RNA sensor that can selectively activate synthetic genes in specific cells, opening up possibilities for targeted therapies for cancer and other diseases. The system uses an enzyme that naturally exists in most animal cells to detect and repair mismatches in double-stranded RNA.
Scientists from the University of North Carolina at Charlotte review nucleolar DNA damage response pathways to combat cancer. By attacking these mechanisms, researchers aim to disrupt cancer's reproduction and growth.
A new radiotracer successfully detected 100% of primary tumors across multiple cancer types, outperforming the current standard. It also showed promise in detecting lymph node and distant metastases, offering a promising alternative for diagnosis and treatment.
A team of researchers at Kyoto University has established a method to identify individual inbred medaka killifish by analyzing the characteristic patterns of dark spots on their heads. This identification method may contribute to biometrics for medical and drug discovery research.
A new study develops an algorithm to decode the coordinated regulation of cell-edge velocity by Rho GTPases, revealing specific characteristics of each enzyme. The model predicts edge velocity from activity time series with high accuracy.
Researchers developed a chemical scissor to split and stitch nanoscopic layers of two-dimensional materials, opening pathways to sustainable energy technologies. This new process allows for structurally splitting, editing, and reconstituting layered materials with exceptional properties.
Researchers found that fomepizole blocked energy production in bacteria and reduced bacterial burden in mice with pneumonia. The combination treatment prevented invasive disease development, suggesting a potential novel treatment for multidrug-resistant pneumococcal disease.
The proposed SpectrumChain framework utilizes blockchain technology to enable secure, efficient, and refined spectrum resource management for 6G wireless networks. It achieves this through a hierarchical architecture comprising a main chain and subchains, allowing for global spectrum resource trading and local spectrum sharing.
A low-cost, open-source device called Flatburn can measure air pollution using 3D printing or inexpensive parts. Researchers have tested and calibrated it against existing state-of-the-art machines, making it suitable for community groups and individual citizens to track local air quality.
The SARS-CoV-2 Omicron XBB.1.5 variant has been characterized for its high transmissibility and infectivity, with a novel mutation in the spike protein facilitating invasion of human cells. Experimental results show that the variant binds to the human ACE2 receptor with high affinity and exhibits strong immune evasion properties.
Scientists at UC Santa Barbara have created a new method to track protein movement in lifelike environments. The TiGGER technique involves tagging proteins with gadolinium ions and tracking their distance using quantum phenomena.
A new study published in European Heart Journal Open found that sleeping less than five hours a night is associated with a 74% raised likelihood of developing peripheral artery disease (PAD). The study also suggests that lifestyle changes such as being physically active and optimising pain management could lower the risk of PAD.
Researchers have developed CAR T cell-based microrobots that can autonomously navigate to tumor sites and exert immune effects. The M-CAR T demonstrated controllable movement and penetrated artificial tumor tissues under magnetic-acoustic sequential actuation.
Researchers found that dogs with anxiety have altered brain connectivity, particularly between the amygdala and hippocampus. The study used fMRI to characterize abnormal neural networks in anxious dogs, providing insight into anxiety disorders in both animals and humans.
A new study from Tokyo Medical and Dental University sheds light on the neural stem cell niche's composition during development. Researchers found that vascular endothelial growth factor-A (VEGF-A) plays a crucial role in maintaining NSPCs under hypoxic conditions, promoting lower rates of cell death and increased cell proliferation.
Scientists at EPFL and IBM have developed a new type of laser using lithium niobate, enabling precise distance measurements in LiDAR applications. The hybrid integrated tunable laser offers low frequency noise and fast wavelength tuning.
The Fermi Gamma-ray Space Telescope has captured a dynamic animation of the gamma-ray sky, revealing frenzied activity over nearly 15 years. The data, now publicly available, includes records of source brightness changes and sheds light on blazars and multimessenger astronomy.
A study of US newspaper articles found that lung cancer screening was generally positively covered between 2010 and 2022. However, crucial aspects such as enrollment criteria and cost issues were frequently omitted, highlighting a need for radiologists to take an active role in media coverage.
A new research paper by University of Alaska Fairbanks Geophysical Institute professor Robert Herrick revealed a nearly 1-square-mile volcanic vent on Venus, changing in shape and growing over eight months. This change is associated with volcanic activity.
A new study highlights the need for testing patients who arrive at hospital intoxicated by drink or drunks to understand how they become intoxicated and reduce feelings of self-blame. The review authors argue that this lack of clarity can exacerbate psychological distress, leading to feelings of guilt, shame, and fear.
A recent study by Iowa State University researchers highlights the varying approaches of NGOs in Turkey and Bulgaria when communicating with the public about migration. Turkish NGOs tend to use a one-way communication mode, while those in Bulgaria are more innovative and engaging, emphasizing personal stories. The findings suggest that...
A multi-state study found COVID-19 mRNA vaccines remain protective during Omicron BA.4/BA.5 predominance, with estimated vaccine effectiveness of 68% against hospitalization within 7-119 days post-vaccination.
The ATS 2023 International Conference Program is now available, offering dynamic scientific programming on pulmonary, critical care, and sleep medicine topics. Attendees can build their daily schedule using the program itinerary and access a series of presentations featuring innovators in the field.
Researchers examine how sugar reduction strategies affect new product sales, finding that smaller package sizes perform better than regular sizes. Sugar reductions work better if they do not overemphasize the reduced sugar content in new additions.
Researchers found that honeybee foragers use waggle dance to provide both polar flight instructions (bearing and distance) and Cartesian-location vectors to approach the source. This new understanding reveals the complexity of symbolic communication in honeybees, adding new insights to the study of their navigational abilities.