The Johns Hopkins ARISE program, developed in 2020, may increase the chances of patients hospitalized with COVID-19 getting discharged to their home rather than to a rehabilitation facility. The program's care model promotes early and individualized intensive rehabilitation to help patients regain functionality.
Scientists from the University of Cambridge have developed a model to predict a planet's interior water capacity based on its size and host star chemistry. The results suggest that larger planets may have drier rocky mantles, while smaller ones could hold more water-rich minerals.
Antimicrobial resistance poses a major threat to human health, with an estimated 4.95 million deaths worldwide in 2019. Researchers identified four research priorities to improve predictive models for antimicrobial-resistant organisms, including better communication and data collection.
Researchers at Karolinska Institutet discovered an immune cell in women with pancreatic cancer that blocks the immune response, leading to poor survival. The study identifies a specific protein FPR2 as a potential therapeutic target for immunotherapy in women.
Dr. Tak W. Mak is being recognized for his groundbreaking work on cancer immunology, including the cloning of the human T-cell receptor beta chain and development of CAR T-cell technology. His research has led to significant advances in understanding immune responses and has paved the way for the development of new cancer therapies.
Cancer develops when genome doubling leads to chromatin disorganization, promoting oncogene activation and genomic instability. Researchers found that WGD causes sub-compartment repositioning and loss of chromatin segregation.
A small study funded by the National Eye Institute found that a unique brain region called the occipital place area (OPA) supports visually guided navigation when walking, but fails to activate during crawling. This finding may help explain how children learn to navigate their surroundings and develop motor skills.
Researchers synthesized a new orthorhombic Sn3O4 polymorph with a narrower bandgap, indicating higher efficiency for visible light absorption. The discovery is significant for photocatalytic reactions such as water splitting and CO2 reduction.
Researchers developed a self-driven lab, AlphaFlow, that uses AI to optimize complex chemical reactions and discover new materials. The system significantly reduces the time needed to develop new chemistries from months to hours.
Revumenib induces remissions in 40% of patients with acute leukemia and uncovers a molecular countermove by which leukemia cells sidestep the drug. The study reveals that menin itself is a valid target for therapy in both genetic subtypes of AML, providing formal proof in patients.
A new study led by University of Maryland researchers found that melted meteorites have extremely low water content, ruling them out as the primary source of Earth's water. The team suggests that unmelted, or chondritic, meteorites may be responsible for delivering water to our planet.
Researchers develop new way to generate squeezing that overcomes fundamental quantum imprecision, enabling more precise atomic clocks and improved quantum sensors. The new approach leverages bosonic pair creation and enables entangled states with minimal fuss, reducing experimental challenges.
A workplace climate survey found that scientists of color, women, and those with disabilities experience higher rates of hostile behavior, including incivility and discriminatory remarks. This has significant implications for retaining scientists in geoscience careers.
A study found that protected areas are unlikely to provide connectivity for species shifting ranges due to climate change, with two-thirds of the world's 30,000 protected areas expected to fail. Conservation strategies must prioritize effective use of protected areas to help species adapt to a warming planet.
A UK study found that climate change beliefs increasingly predict opposition to natural gas extraction. Support for North Sea gas development decreased from 80% in 2019 to 70% in 2022 as concerns about climate change grew.
The study reveals hydrated salts can lose their facets and become soft when slowly dissolved in humid air, exhibiting liquid-like molecular mobility at their surfaces. This finding challenges the conventional understanding of crystal formation and behavior.
A team of researchers at USTC has developed a stable single-site copper coordination polymer that significantly improves the efficiency of ethylene production through electroreduction of CO2. The catalyst enables efficient carbon-carbon coupling without compromising its structural stability.
A new MIT study explains how the brain manages general and specific components of working memory, enabling flexibility in task demands. Spatial Computing theory proposes that distinct spaces in the cortex govern rule-based control, allowing for dynamic reshaping of memory representations.
Researchers found that restoring function to donor hearts through taNRP can significantly increase the donor pool, leading to more transplantations. The study showed comparable survival rates between DCD and DBD heart transplants, with 97% of patients surviving for over 30 days.
A new University of Alberta study found that untreated moderate fever helped fish clear their bodies of infection rapidly and repaired damaged tissue. The research suggests that waiting before reaching for medications may be beneficial for humans.
A world-first study from the University of South Australia is providing valuable insights into how young people understand chronic pain, potentially helping thousands of sufferers to better manage their symptoms and long-term wellbeing. Researchers found that young people tend to make sense of chronic pain by explaining it as a softwar...
A team of researchers from the University of Michigan has developed a way to control the degree of twist in nanostructured particles, opening up new avenues for machine vision and medicine production. The development enables robots to accurately navigate complex environments by encoding information in twisted light, which is preferenti...
A new study found that bupropion, an antidepressant medication, can help people stop using cocaine while receiving methadone for opioid use disorder. Participants who received monetary incentives to quit cocaine saw a higher success rate when taking bupropion compared to those with placebo.
Researchers detected significant thermospheric fluctuations with multiple wave modes after the Tonga eruption, affecting global neutral density up to 500 km altitude. The study suggests that gravitational waves, Lamb waves, and tsunami waves may transmit energy upward, influencing thermospheric density.
A team of researchers has developed a sensitive method to detect viral nucleic acids using 'glow-in-the-dark' proteins, achieving high sensitivity and speed for clinical diagnostic tests. The LUNAS assay successfully detected SARS-CoV-2 RNA in under 20 minutes at low concentrations.
Researchers at UC San Francisco have created the first molecular-level picture of how an odor molecule activates a human odorant receptor, opening doors to creating novel smells. This achievement paves the way for new insights into biological processes, including fragrances and food science.
A clinical study found that children ages 2 to 6 with type 1 diabetes using an artificial pancreas system spent more time in their target blood sugar range, reducing anxiety for families. The system improved nighttime blood glucose control and was used safely by participants.
A study found that self-reported sleep quality is significantly associated with quality of life for individuals over time and when comparing between people. High-quality sleep improves quality of life regardless of sleep duration or timing.
A large study of women with rheumatoid arthritis found that those taking oral contraceptives or hormone replacement therapy had a greater chance of achieving remission. The study suggests female sex hormones could play a major role in improving outcomes for these patients.
Researchers found that consuming vitamin A or its analogs can help prevent painful pancreas inflammation in children and young adults with acute lymphoblastic leukemia (ALL) during chemotherapy treatment. The study revealed that only 1.4% of patients developed pancreatitis when taking vitamin A, compared to 3.4% without it.
Isabelle B. Cooperstein, a PhD candidate, receives the 2023 David L. Rimoin Inspiring Excellence Award for her work on rare disease diagnosis tools. Her research aims to create accessible diagnostic solutions using Human Phenotype Ontology and sequencing data.
The University of Hawaii at Manoa has released a new catalog of exploding stars, including nearly 2,000 supernovae and other luminous variable objects. The data, collected over three years using the Pan-STARRS telescope, provides a wealth of information on these cosmic events.
The TOAST project, led by Aarhus University, aims to develop the Tactile Internet technology and upscale the talent pool for this emerging field. Researchers will focus on edge intelligence, haptic communication, and machine learning to create immersive user experiences.
Researchers designed a novel porous insulator contact to reduce non-radiative charge recombination and improved power conversion efficiency. The study achieved an efficiency of up to 25.5% without sacrificing photocurrent transport.
Researchers discovered that targeting two inflammatory regulators simultaneously can boost T cell expansion and increase antitumor immune activity in models. The findings showed at least 10 times greater T cell expansion when both regulators were knocked out, resulting in improved durability.
A study analyzed news reports on Brazilian deer species between 2011 and 2021, finding that news coverage gave different weights to threats compared to the IUCN Red List. News items properly identified main threats like poaching and habitat loss but underestimated livestock diseases and overestimated road kill.
A University of Illinois project uses AI-powered object recognition to quantify kernel damage in wheat, enabling faster disease analysis and improved resistance. The technology has shown promising results, with potential for an online portal to automate scoring and support breeders in their efforts to eliminate fusarium head blight.
Health disparities in lung nodule follow-up and treatment are a major concern, with Black and Latino patients at higher risk of delayed follow-up. Researchers have identified prioritized research questions to mitigate these disparities, focusing on patient-clinician communication and culturally trained multidisciplinary teams.
After Hurricane Maria, the African tulip Tree's total biomass increased, potentially reclaiming its prominence among native tree species in Puerto Rico. This shift was attributed to improved light conditions in forest canopies post-hurricane damage.
The ACMG Foundation presented four Next Generation Fellowship Awards to Amélie Pinard, Mina Tabrizi, Herodes Guzman, and others. These awards recognize the support of Bionano Genomics and Sanofi and aim to advance medical genetics and genomics specialties.
Researchers at NIMS found that a lithium negative electrode degrades rapidly during charge/discharge cycles, causing overpotential and short cycle life. Using a lightweight protective layer, they extended the battery's cycle life without compromising its high energy density.
Children from low-income neighborhoods are more likely to develop preventable heart disease due to high blood pressure, according to a new study. The research highlights the importance of considering neighborhood-related factors when diagnosing hypertension in youth.
A new study from the University of Eastern Finland shows that equine-facilitated therapy (EFT) can improve daily functioning and reduce perceived pain among patients with chronic low back pain. Statistically significant improvements were observed in domains such as sleep, reaching, and bending forward.
Research found associations between teachers' and students' anxiety in math, science, and literacy. The study highlights the importance of considering affective elements of teaching and learning, particularly in STEM content areas, which can impact students from underserved socioeconomic backgrounds.
Researchers discovered extensive use of iron staples in Notre-Dame's construction, dating back to the 1160s, making it a pioneering example of iron-based architecture. The study sheds light on the medieval Parisian iron market and its role in shaping the city's history.
A donation of nearly 120 rechargeable hearing aids has been made to address the hearing health care crisis among Ukrainian refugees in Poland. The Heart of Hearing team, led by King Chung, PhD, conducted a successful otoscopy exam and fitting session for approximately 66 individuals who needed hearing aids for the first time.
A study by University of Connecticut researchers examines three conservation network strategies to minimize the negative impacts of habitat loss and fragmentation. They found that non-random approaches, such as incorporating five to ten interconnected sites, are more effective at consistently maximizing species richness.
Researchers at the Francis Crick Institute found that high doses of sucralose lower activation of T-cells in mice, which could lead to new treatment options for autoimmune diseases. The study suggests that sucralose may be used therapeutically to dampen T-cell responses.
Researchers used PET and electron microscopy to create detailed maps of mitochondrial networks in lung tumors. They found distinct subpopulations of mitochondria organizing with organelles to support tumor cell metabolism.
Researchers developed a bottom-up synthetic strategy to create ultrathin MOF nanosheets coated with high-loading single cobalt atoms, leading to improved photocatalytic CO2 reduction rates and selectivity. The resulting catalyst exhibits exceptional performance under visible-light irradiation.
This study analyzes the relationship between specific skills taught in US undergraduate degree courses and graduate earnings. The research found that certain skills, such as communication, teamwork, and problem-solving, have a significant impact on post-graduation salaries.
A team of researchers found the earliest evidence of heated gas in a galaxy protocluster, indicating temperatures characteristic of the present-day 'Warm-Hot Intergalactic Medium'. This discovery provides insight into the mechanisms that caused the intergalactic gas to boil up and offers a unique window into the early universe.
Researchers at the University of Bath are developing technology to photograph residual limbs remotely, enabling faster and more accurate prosthetic socket fittings. This project aims to improve rehabilitation outcomes and quality of life for amputees worldwide, particularly in low- and middle-income countries.
A new study finds that tax interventions needed to combat climate change will need to be larger and more effective than previously thought. Improvements in energy efficiency technology are crucial, but technological adjustments take time.
A new open-source tool called TILE2NET uses aerial imagery and image-recognition to create complete maps of sidewalks and crosswalks. The tool has been trained on 20,000 aerial images from Boston, Cambridge, New York City, and Washington, recognizing 90% or more of all sidewalks and crosswalks in these cities.
A new study highlights poor access to US methadone treatment compared to Canada. The average driving distance to the closest clinic was more than three times greater in the US, with rural areas requiring drives of up to 138 miles.
A recent WHO review reveals a significant shortage of new antibiotics in the pipeline, with only 12 approved drugs introduced between 2017 and 2021. The majority of these drugs target non-critical pathogens, leaving critical ones like Acinetobacter baumannii and Pseudomonas aeruginosa underrepresented.
A machine-learning model was trained on 10 million tweets to infer users' subjective wellbeing. The study found that New Year's Day is the most popular holiday, followed by Defender of the Fatherland Day and International Women's Day. The researchers also discovered gender differences in attitudes towards certain holidays.
Researchers have identified evidence of ongoing volcanic activity on Venus based on radar images from the Magellan spacecraft. A vent in the Maat Mons volcano system appears to be changing shape and growing larger between two imaging cycles.
Researchers at the University of Bern have determined the structure of the canine distemper virus docking protein, enabling the development of tailor-made active substances to prevent virus entry into host cells. This breakthrough paves the way for novel therapies and antiviral drugs against this highly contagious viral disease.