A study of over 1,300 children aged 9-13 found a significant increase in substance use when combining hair analysis with survey results, nearly doubling the estimated number of child drug users. This suggests that hair analysis is a more accurate method for assessing adolescent substance abuse than self-reporting alone.
Pancreatic cancer is an incurable form of cancer, but gene therapies are being developed to treat it. The article reviews ongoing clinical trials and discusses various biotherapies, including vaccines and CAR-T cell therapy.
Researchers have identified a key cause of metastasis from aggressive brain cancer in children and found a potential new therapy. Medulloblastoma cells hijack neurodevelopmental signaling pathways to promote tumor cell spreading. Targeting these pathways with a drug called dasatinib has shown promise in killing metastatic tumors.
Researchers identified distinct viral signatures in the gut viromes of SLE patients, including Drulisvirus and Thermoanaerobacterium phage THSA-485A, which promote interferon-α production. These findings suggest a link between the gut virome and SLE disease activity.
Researchers at Argonne National Laboratory have created a stable spin qubit in a carbon nanotube, achieving record-long coherence times of up to 10 microseconds. This breakthrough enables the integration of quantum devices and provides a platform for storing information through vibrations in the flexible tubes.
A new type of planning document called the multidisciplinary rounding plan (MDRP) offers relevant information for use in patient care, compared to traditional nursing care plans. The MDRP provides more concrete, patient-specific information and is written in a plain-speech style.
Researchers have developed high-member low-dimensional Sn-based perovskite solar cells using phenethylammonium thiocyanate, which improves their efficiency and reduces bimolecular recombination rates. The new structure has a higher crystal quality, leading to enhanced power conversion efficiency.
A biological messenger called interleukin-33 (IL-33) plays a crucial role in maintaining cytotoxic T cells' 'marathon runner' state, allowing them to provide sustained immunity against chronic infections. This finding has implications for improving treatment of hepatitis C and cancer immunotherapy.
A cheap charcoal air filter can significantly improve in-vehicle air quality, reducing nitrogen dioxide (NO2) levels by up to 90%. The study found that NO2 concentrations were on average 14.3 times lower with activated carbon filters fitted compared to pollen filters.
Researchers have developed a robotic system called AngleNet that measures leaf angles on corn plants, providing plant breeders with accurate data more quickly. The technology uses stereo vision and deep convolutional neural networks to capture images of leaves at different heights, enabling 3D modeling and precise measurements.
Researchers at UCLA have developed a new type of solar roof that can harness energy from sunlight without blocking light for plants. The innovative design uses semi-transparent organic solar cells with a layer of L-glutathione, which extends the cells' lifetime and improves efficiency.
A model predicting oxygen levels in freshwater streams, developed by WVU researcher Omar Abdul-Aziz, helps determine stream pollution and health. The tool allows citizen scientists to take action on stream pollution, with potential applications for implementing the Clean Water Act.
New study by Curtin University researchers finds that silicon, gold, and copper can trap and destroy the spike proteins of SARS-CoV-2, likely killing the virus. The materials can be used in air filters, coatings, or fabric to capture coronaviruses and prevent infection.
Researchers found that levee building and subsurface resource extraction account for 40% of land loss in the Mississippi River Delta. A new sediment diversion project may help reverse land loss by releasing sediment into the Barataria Basin.
Research suggests that withholding gender-affirming hormone therapy from transgender individuals may have negative mental and physical effects. A new study provides comprehensive guidance for assessing, managing, and treating venous thromboembolism in transgender patients receiving feminizing hormone therapy.
A recent study found that diversity trainings for police officers are ineffective in changing behavior, as intentions to use strategies decrease over time. The researchers recommend embedding lessons with other organizational initiatives and providing 'super-tailored strategies' to address specific daily work activities.
The U.S. laboratory system needs improvement to ensure timely and accurate diagnosis, tracking, and response to infectious diseases like COVID-19 and Mpox. The authors suggest government and private institutions collaborate to implement systemic changes, including federal funding and public-private partnerships.
A new German Research Foundation-funded project investigates the possibility that a Roman land ditch was created in the Hessian Ried in the 1st century AD. The research aims to find the canal's original course and study its relationship with nearby Roman settlement sites.
A Scripps Research team has found that heavy alcohol consumption increases brain inflammation, leading to changes in signaling pathways and behavior. The study suggests a potential new drug target for treating alcohol use disorder by targeting the interleukin-1β pathway.
Research at Cornell University found that co-locating solar panels with commercial agriculture can improve power conversion efficiency and solar-panel longevity. Agrivoltaic systems offer increased passive cooling through taller panel heights, more reflective ground cover, and higher evapotranspiration rates.
A University of Michigan study suggests that exhaled breath contains unique volatile organic compounds (VOCs) that can mark distinction between COVID-19, variants and non-COVID illnesses. The researchers developed a portable gas chromatography device to analyze breath samples with high accuracy.
High-dose anticoagulation reduces intubations and deaths by 30% in hospitalized COVID-19 patients, especially those with ARDS. The study found a significant reduction in mortality and need for ICU care among patients treated with therapeutic anticoagulation.
A new study published in BMC Public Health suggests that problematic social media use in preteens is linked to both positive and negative alcohol beliefs. Researchers found that 97% of social media posts display alcohol in a positive context, contributing to positive perceptions among adolescents.
Researchers have identified a gene network underlying rice grain size regulation, revealing a phosphorylation-driven auxin signaling pathway. The study found that OsTIR1–OsIAA10–OsARF4 plays a crucial role in controlling rice grain size and weight.
A new consensus statement calls for routine radiological screening of contact children in suspected child physical abuse cases to prevent further harm. Siblings are at risk of experiencing physical abuse, with a strong association between index and contact children.
A new study by Intermountain Health found that long-term intermittent fasting can lead to better outcomes in COVID-19 patients who required cardiac catheterization. Patients who practiced regular fasting had a lower rate of heart failure-related hospitalization, complications, and death compared to those who did not fast. The study sug...
A recent study published in Antioxidants & Zoological Research found that moderate static magnetic fields can delay natural aging in healthy mice and alleviate chronic kidney injury induced by chemotherapy. High-grade exposure, however, had detrimental effects on diabetic mice, including organ damage and reduced survival rates.
A study found that gestational iron deficiency may contribute to cognitive impairments like autism, ADHD, and learning disabilities. Researchers identified a specific embryonic neuronal progenitor cell target for GID, which disrupts interneuron development.
Researchers found that trust in federal, state, and local public health agencies was driven by beliefs in scientific expertise and provision of direct care, not control of outbreaks. Lower trust was related to concerns about conflicting recommendations and perceived political influence.
A novel AI architecture, relational reasoning network, accurately identifies anatomical landmarks in CT scans for orthodontic treatments. The model learns spatial relationships between landmarks without explicit image segmentation, achieving accuracy comparable to conventional methods.
Researchers have found that honeybees use linear landscape elements, such as irrigation channels, to guide their search flights when looking for their hive in new areas. The bees retain a navigational memory of their home area based on these elements, which they generalize to the new area to find their way home.
A nationwide Danish trial found that emphasizing cardiovascular benefits and a repeat-letter strategy increased vaccinations by 0.89% and 0.73%, respectively. These low-cost interventions have the potential to overcome vaccine hesitancy in high-risk populations, preventing illnesses, hospitalizations, and deaths.
The study found that oxidized membranes accelerate the aggregation of certain peptides associated with Alzheimer's disease, while others are prevented from aggregating. The research provides new insights into the mechanisms underlying peptide aggregation near lipid membranes.
A recent study published in Cell Discovery found that high levels of folic acid supplementation may increase DNA mutation rates and impair DNA repair mechanisms. The researchers discovered a 'Goldilocks Effect' where too little or too much folic acid is detrimental to human health.
A Phase 1 clinical trial of AAHI's thermostable, freeze-dried single-vial ID93 + GLA-SE vaccine candidate showed higher levels of antibodies and favorable cellular immune responses compared to the two-vial presentation. The results represent significant progress in global efforts to combat TB.
Researchers at Fritz Haber Institute develop a new technique to analyze negatively-charged chiral molecules using PECD spectroscopy. The method offers improved sensitivity and ability to distinguish between enantiomers, enabling the study of isolated molecules at low concentrations.
Leading medical organizations have formed a coalition to combat the growing problem of firearm violence in the US. The Healthcare Coalition for Firearm Injury Prevention aims to promote education, advocacy, and community-centered approaches to reduce firearm-related injuries.
A new analysis finds that Canada's physician workforce is facing significant challenges due to an aging population and decreasing working hours. The study suggests that traditional metrics for workforce planning are misleading, and a more nuanced approach is needed to inform government and medical profession decisions.
A new cutaquig study found that increasing infusion volume per site resulted in a reduction of injection sites, while increasing infusion rates decreased infusion duration. The research also showed that dosing every other week demonstrated equivalency to trough levels with weekly dosing.
Researchers used drones to map large areas of Antarctica, capturing unprecedented high-resolution imagery of vegetation and biodiversity in protected areas. The vision identified areas with moss and lichen not previously picked up by satellite, providing valuable insights into the fragile ecosystem.
Researchers from Shanghai Astronomical Observatory detect radio recombination lines of carbon and oxygen ions for the first time, using the TianMa 65-m Radio Telescope. The discovery allows for accurate measurement of element abundances and has significant implications for studying interstellar chemistry and molecular formation.
A global study has found that greater gender equality is associated with longer life expectancy for both women and men. The study, published in the lead up to International Women's Day, suggests that addressing longstanding gender inequality can help extend longevity for all genders.
A new study by University of Vienna psychologists debunked the Mozart effect myth, finding no reliable evidence for symptom relief in epilepsy patients. The researchers attribute this alleged effect to selective reporting, small sample sizes, and inadequate research practices.
A nationwide study found that over 25% of parents lied about their child's COVID-19 status or didn't follow guidelines. Some parents misrepresented their child's age to get vaccinated, highlighting the challenges faced by parents during the pandemic.
A novel photoinduced electron transfer-triggered sensing system using g-C3N4 nanosheets and rhodamine B detects carbendazim residues selectively and quantitatively. The system shows a low detection limit of 5.89 nM, allowing for rapid visual response to trace levels.
Researchers found that mineral-organic carbon preservation slowed down decomposition, allowing atmospheric oxygen levels to increase unhindered. This process enabled complex life forms to evolve and ultimately led to the development of intelligent life on Earth.
The HALP score, a novel immune-nutritional marker, has been linked to prognostic ability in different cancer types. It integrates indicators of immune status and nutritional status, showing promise as a cost-effective biomarker.
Researchers developed a simple purification method using surfactants to separate hydrophobic DNA nanostructures from aggregates, enabling the construction of artificial cells and complex functions in molecular robots. The purified structures retain their ability to bind lipid vesicle surfaces.
A new study found significant links between sleep disturbances and the risk for developing dementia over a 10-year period. Sleep-maintenance insomnia was associated with a lower risk of dementia, while sleep-initiation insomnia and sleep medication use were linked to an increased risk.
Researchers found that no single helmet design consistently reduced concussion incidence, with the back of the helmet showing vulnerabilities. The study suggests combining lab tests with field-based impact tracking could provide better protection for athletes.
A new study of over 30,000 patients taking statins found that inflammation is a stronger predictor of cardiovascular risk than cholesterol. Aggressive treatment of vascular inflammation can help maximize patient outcomes and reduce cardiovascular events.
A recent study found that the incidence rates of type 1 and type 2 diabetes continue to rise in children and young adults in the US. Non-Hispanic Black and Hispanic youth were particularly affected, with higher incidence rates compared to non-Hispanic white peers.
Researchers found that levee building and extracting subsurface resources are the main causes of land loss in the Mississippi River Delta, accounting for 40% each. The study suggests that reducing subsurface resource extraction may have slowed down land loss, offering a rosier outlook for restoration projects.
Global virus network experts propose changes to global polio eradication strategy, emphasizing the need for high vaccination coverage and adaptable policies. They suggest using both inactivated and live, weakened vaccines, as well as reconvening a scientific advisory group to respond to new data and public health emergencies.
A team of scientists developed a humidity-resistant hydrogen sulfide sensor using polydimethylsiloxane, improving long-term stability and selectivity. The membrane acts as a molecular sieve to block larger molecules, ensuring the sensor's accuracy in detecting H2S.
A new study by Monash University found that almost nowhere on Earth is safe from air pollution, with only 0.001% of the global population exposed to safe levels of fine particulate matter (PM2.5). The study, which analyzed data from 2000-2019, revealed increasing pollution levels in Southern Asia, Australia, and Latin America.
Researchers from ETH Zurich have achieved groundbreaking cooling of a glass nanoparticle along two directions of motion, overcoming the 'Dark Mode Effect'. This breakthrough enables the creation of fragile quantum states and paves the way for ultrasensitive gyroscopes and sensors.
A new study found pregnant people with schizophrenia are three times more likely to experience emergency department visits for interpersonal violence. The research emphasizes the importance of routine violence screening in antenatal care settings to prevent harm to patients and their children.
Researchers explore how AI language models like ChatGPT understand and respond to user input, mirroring their users' intelligence. The Reverse Turing Test reveals that chatbots reflect the intelligence level of their interviewers, incorporating their biases into responses.
Researchers designed a heterostructured interface for Zn batteries with ultrahigh areal capacity and energy density. The new design stabilizes electrodeposition and dissolution of Zn at high capacities, enabling excellent cycling stability.