Researchers found SARS-CoV-2 in 18.2% of tear samples from patients with COVID-19, and in 12.1% of those collected using the Schirmer strip test. The method may predict patient prognosis and provide an alternative to uncomfortable nasopharyngeal swabbing.
The new Cell Atlas updates reveal that 20% of all neurons in the mouse brain are inhibitory, with detailed information on morphological and electrophysiological properties. The atlas combines various datasets to create a coherent framework for simulating neural circuits.
Researchers found that gadolinium nanoparticles from MRI contrast agents can infiltrate kidney cells, causing severe side effects like nephrogenic systemic fibrosis. The study used electron microscopy to detect tiny deposits of gadolinium in the kidneys of people who had been injected with contrast agents prior to their MRIs.
A modelling study by an international team of researchers found that climate change will likely disrupt core habitats of marine species, reducing suitable ranges by the end of this century. The results highlight the need for effective conservation management to protect marine biodiversity and resources.
A new study finds that flood zone property prices are overvalued by $121–$237 billion, with low-income households losing up to 10% of their market value. The study warns of a real estate bubble threatening the US housing market's stability.
Physicists at the University of Wisconsin–Madison directly measured the fluid-like flow of electrons in graphene for the first time at nanometer resolution. This breakthrough study provides new insights into the behavior of electrons in this material, shedding light on its potential applications.
Researchers found that single copy loss of CDKNA/B genes accelerates aggressive meningioma recurrence and offers a poor prognosis. The study suggests refining diagnosis by identifying group C tumors and further checking for CDKN2A/B gene loss.
Researchers analyzed two US Army Corps of Engineers flood megaprojects in Rhode Island that emerged simultaneously after hurricane activity around the 1950s. The study found that strong public support and political backing were crucial factors in advancing one project, while the other failed to gain momentum due to environmental concer...
Scientists at Rice University have developed a new technique using the 'flash Joule' method to transform plastic waste into high-value carbon nanotubes and hybrid nanomaterials. This process is more energy-efficient and environmentally friendly than traditional methods, making it a promising solution for recycling plastic waste.
Rice University scientists have developed a method to engineer wood that traps carbon dioxide while increasing its strength. This process involves removing lignin and hemicellulose from the wood and replacing them with metal-organic framework particles, making it a sustainable alternative to traditional materials.
A comprehensive review and meta-analysis published in The Lancet suggests that natural immunity from COVID-19 infection provides significant protection against hospitalization, symptomatic disease, and severe illness for at least 10 months. However, this protection declines over time, with an estimated 85% protection rate at one month ...
Scientists from SUTD design a novel thermal-based therapy nano-system that destroys over 20% of pancreatic cancer cells using microsecond electrical pulses, improving cancer cell targeting accuracy and bio-compatibility. The introduction of the M13 virus enhances electro-thermal therapy performance by assembling more on cancer cells.
Researchers analyzed data on European travellers arriving from Africa between 2015 and 2019, finding malaria as the most common arthropod-borne disease. The study highlights the importance of using travellers' health data to complement local surveillance systems in Africa.
A European-wide recall of Kinder Chocolate products, including eggs, prevented thousands of extra cases of Salmonella Typhimurium. The recall, triggered by intensive collaboration between public health experts, food safety agencies, and regular surveillance, saved lives and reduced the risk of devastating global outbreak.
Researchers at Yale University have discovered a volatile pheromone emitted by the tsetse fly, which could be used to control their populations and slow the spread of diseases like African sleeping sickness and nagana.
Researchers at the University of Virginia Health System have identified a vital contributor to hyperactive immune responses and neuroinflammation in multiple sclerosis. Blocking this regulator alleviated harmful inflammation in lab mice, suggesting a potential therapeutic target for new treatments.
A new study from Lund University suggests that allowing patients to describe their mental health in free language can provide more precise diagnoses than traditional rating scales. The AI-tool, developed by researchers, enables doctors to analyze patients' answers and provides individualized care.
Researchers use heavy hydraulic presses to mimic early Earth's conditions and recreate the differentiation process in miniature. They found that iron melts could pass through grain boundaries, exchanging chemical elements like oxygen and sulfur with the surrounding mantle.
The article analyzes digital microfluidics' (DMF) benefits for bacterial protocols, highlighting its versatility and potential applications in synthetic biology and diagnostics. DMF's electrostatic forces manipulate microdroplets on a plate, enabling sample preparation and nucleic acid detection.
Researchers at Virginia Tech have identified a critical molecule in the development of brain's stress response, which may lead to better understanding of stress-related mental health disorders. Deficiencies in DSCAML1 disrupt brain development and increase cortisol levels, leading to imbalanced stress responses.
Researchers at the University of Bern and Empa have developed a new technique to measure greenhouse gases in ancient ice cores, enabling more accurate climate records. The method allows for high-resolution analysis of the oldest ice, which contains 15,000 to 20,000 years of climate history compressed into one meter.
A comprehensive analysis of over 1,000 studies reveals risk factors for severe COVID-19, including age, underlying diseases, sex, pregnancy, genetic polymorphisms, lifestyle, and environmental factors. The study highlights the complex interactions between these factors and their impact on disease outcomes.
A new UC San Diego model uses internet search data to predict housing price declines, with a national forecast of a 5% decrease. Cities like San Diego and Phoenix are predicted to experience significant price drops, while others, such as Scranton-Wilkes-Barre-Hazleton and Kansas City, are expected to see stable prices.
Researchers have discovered a late-stage small molecule inhibitor called rebecsinib that reverses ADAR1-induced cancer stem cell cloning capacity. This breakthrough has significant implications for treating various types of cancers, including acute myeloid leukemia and chronic myeloid leukemia.
Pediatric patients with LEP face challenges in emergency rooms, but a CHOP study shows that implementing quality improvement measures can increase the use of medical interpreters and improve documentation of language needs. The research team introduced new processes to identify language needs and offer interpreters as needed, leading t...
A team of scientists has discovered that changing the structure of psyllium fibre can promote healthy gut bacteria and reduce gas formation. The findings have significant implications for people with fiber intolerances and irritable bowel conditions.
A new study found that Black and Hispanic patients are more likely to experience persistent symptoms or be diagnosed with a new medical condition after COVID-19. The study analyzed data from over 60,000 patients and found significant racial and ethnic disparities in the frequency and types of post-COVID-19 symptoms.
Replacing red and processed meat with Quorn's mycoprotein reduces intestinal genotoxins, a risk factor for bowel cancer, and increases beneficial gut bacteria. The study found significant reductions in harmful chemicals and improvements in gut health in participants consuming the mycoprotein diet.
Researchers found that the Paleocene-Eocene Thermal Maximum, a 5-8°C warming event, was caused by high carbon dioxide and methane levels. The team's study provides new insights into sedimentary systems and the impact of seasonal changes on ocean turbidity.
Researchers at UC Davis found that engaging serotonin 2A receptors inside neurons promotes growth of new connections, while the same receptors on cell surfaces do not. This discovery guides efforts to develop new treatments for depression and PTSD.
Researchers have discovered a method to detect α-synuclein aggregates in stool samples, indicating an early form of Parkinson's disease. This finding could lead to the development of a non-invasive diagnostic tool, enabling therapies to be initiated at an early stage.
A decade-long experiment found that high-intensity fires did not reverse bush encroachment in the long term, despite an initial decline in woody plant cover. The study suggests that fire management strategies must be tailored to each local context and that long-term monitoring is crucial for effective conservation.
A new approach, CAITE, leverages copyleft licensing and patent trolling to regulate AI development and deployment. The system would enforce ethical terms and conditions on AI products and derivatives.
The third annual Rising Black Scientists Awards recognize four winners from diverse scientific disciplines, including computer science, biochemistry, and conservation biology. The recipients share their aspirations and research goals, highlighting the importance of diversity and inclusion in STEM fields.
New research from Texas McCombs finds that most nonrecurring income taxes are driven by legitimate business causes rather than efforts to manipulate earnings. The study analyzed 68,139 quarterly earnings reports and found no predictive power for future profits or tax rates.
Researchers at the University of Groningen have discovered the exact structure of polydopamine coatings, which could lead to new applications in surface adhesion and neurodegenerative disease treatment. The study found that these coatings form through auto-oxidation, crosslinking and isomerization processes.
Researchers at Washington State University found that CBD inhibits a key enzyme for nicotine metabolism, slowing down its effects and allowing smokers to wait before feeling the urge to smoke. The study suggests that CBD could be a useful tool in reducing harm from smoking and quitting nicotine addiction.
The new clinical document defines the required competencies for interventional cardiology, providing trainees with information to support training across all areas. Trainees must acquire experience working as part of a multidisciplinary team and complete a minimum of 250 procedures.
A new study reveals that rising energy prices triggered by the Russia-Ukraine conflict could push up to 141 million more people around the globe into extreme poverty. Households' energy costs are likely to rise by 62.6% - 112.9%, contributing to a 2.7% - 4.8% hike in household expenditure and cost-of-living pressures.
The Carnegie Mellon Portugal initiative offers up to 12 Ph.D. scholarships for the 2023/2024 academic year in selected ICT areas. The selected candidates will be hosted by Portuguese universities and benefit from a research period at CMU, with full tuition fees and stipend support.
Verkko software assembles gapless human genome sequences quickly and precisely, enabling better assessment of genomic diversity and comparative genomics. This innovation accelerates efforts to generate complete genome sequences of various species, improving research and discovery in the field.
Researchers have developed a hand-held device that can rapidly and accurately identify lesions in the mouth that will develop into cancer. The Liverpool Diagnostic Infrared (LDIR) Wand employs infrared lasers to predict future cancer risk based on machine learning analysis.
A new study by the University of Illinois at Urbana-Champaign demonstrates an approach for integrated capture and conversion of nitrate-contaminated waters into valuable ammonia using a single electrochemical cell. The device shows significant enhancements in energy efficiency, nitrate removal, and ammonium production rate compared to ...
A study found that dog puppies but not kittens and wolf pups spontaneously imitate human actions, even when unrewarded. The researchers believe this can inform novel training methods less dependent on food rewards.
Research suggests that tropical tent web spiders can eat a devastating pest moth of commercially important crops like tomato and potato. The spiders' ability to form groups and create large webs makes them effective biological control agents.
The Operation Pangolin project aims to save the world's eight pangolin species by generating data to inform conservation strategies and implementing wildlife crime prevention efforts in Central Africa. The team will use novel technology and artificial intelligence methods to address the illicit wildlife trade and prevent extinction.
The American Society for Nutrition has published a comprehensive summary of the landmark White House Conference on Hunger, Nutrition, and Health. The conference outlined ambitious goals to end hunger and improve nutrition security by 2030, with recommendations from President Biden's National Strategy.
The US is not prepared to combat the spread of animal-borne diseases due to gaps among governmental agencies. A 'One Health' approach is needed to govern human-animal interactions effectively.
Researchers found serial dependence bias in tasks that require guessing coin values, indicating its impact on higher-order cognitive processing. The study suggests this bias can be minimized by presenting information in an environment that reduces human error.
A new study published in Biogeosciences suggests that agricultural soil erosion may actually create an organic carbon sink, rather than a source. The researchers argue that the 'geomorphic OC pump' transfers organic carbon from the atmosphere to upland soils, which can be stored in sedimentary environments.
Researchers at the University of Rochester have developed a novel method to boost the light conversion efficiency of perovskites by 250 percent using substrates of metal and dielectrics. This breakthrough could lead to more efficient solar cells and detectors.
Researchers have made significant progress in developing high-performance Pt-based nanocatalysts for oxygen reduction reactions, focusing on increasing activity per site and active sites. The study aims to reduce the cost of PEMFCs by overcoming the challenges associated with Pt metal catalysts.
Researchers developed an antibiotic that cured mice infected with nearly untreatable bacteria, with virtually undetectable resistance to the drug. The unique mechanism of action targets multiple bacterial functions, disrupting the bacterial membrane and leading to broad-spectrum antibacterial activity.
Researchers at UToledo discovered a way to enhance adhesion and mechanical toughness in perovskite solar cells using DPPP, improving durability and power conversion efficiency. The breakthrough allows for the commercialization of new photovoltaic technology to replace silicon and lower cost of solar electricity.
Researchers developed a machine learning algorithm to predict the chances of successful prime editing gene edits, assessing thousands of DNA sequences and identifying key factors such as sequence length and DNA repair mechanisms. The tool promises to speed up efforts to bring prime editing into the clinic.
Researchers used AgRenSeq genomic discovery method to identify two genes protecting experimental wheat plants against wheat blast. The study highlights the power of heritage wheat varieties and wild grass relatives in providing disease-fighting diversity.
Aleksandar Obradovic's work harnesses anti-tumor immune response with tailored cancer immunotherapy, combining drug treatments and immune-response therapeutics. He developed algorithms to predict drug sensitivity and identify groups of cells associated with treatment resistance.
Researchers at UEA have engineered antibody fragments that can be activated by UV light to target cancer cells, offering a new generation of highly targeted treatments. This breakthrough could lead to reduced side effects and improved efficacy for patients with skin or solid tumours.
A new study by the University of Illinois at Urbana-Champaign reveals that even with broad coverage, public transit systems may still exclude low-income and vulnerable populations. The researchers used a GIS-based approach to evaluate travel times by location and economic conditions, finding that routes often leave behind those who rel...
Researchers discovered that sensory signals are underrepresented in cortical pyramidal neurons of people with Fragile X syndrome (FXS), a common cause of autism. This finding could lead to new therapeutic strategies and improved perception of sensory signals.