A new study reveals that consumers place a higher value on products from circular economies due to the concept of psychological ownership. This finding suggests that businesses and policymakers can align strategies with consumer values to promote sustainable initiatives.
Researchers at The Wistar Institute have engineered novel monoclonal antibodies that engage Natural Killer cells through Siglec-7, a conserved glyco-immune marker, to fight against cancer. These new approaches demonstrate preclinical feasibility and potential for treating treatment-resistant ovarian cancers.
A new research project will explore the potential for low-lying coral atoll islands to survive the impact of rising sea levels, contradicting previous forecasts. The five-year £2.8m ARISE project will conduct extensive field tests and laboratory experiments in the Maldives and Pacific.
A Finnish study found that maternal microbiota affects foetal development by altering gene activity in the intestine, brain, and placenta. The researchers identified previously unknown compounds in the fetus that are likely to be microbial, shedding light on the significance of the microbiota in individual development and pregnancy.
Researchers have made significant progress in understanding a pathway contributing to liver fibrosis. Paxillin has been found to play a key role in the activation of hepatic stellate cells, leading to excessive extracellular matrix production and scarring. This discovery holds promise for developing new treatments for liver fibrosis.
A new study provides preliminary evidence that an existing drug, α-difluoromethylornithine (DFMO), could be used to treat type 1 diabetes. The drug has already been FDA-approved for other indications and may offer a more convenient treatment option for patients.
A new study reveals that CD8+ T cells control HIV infection by both cytolytic effects and non-cytolytic suppression of virus production. The research team used computer modeling and experiments with macaques to understand the immune system's mechanism in controlling HIV infections.
Dr. Alan Jobe, MD, PhD, is recognized for his pioneering work in neonatal lung diseases, advancing the field of bronchopulmonary dysplasia research. The APS John Howland Award acknowledges his commitment to improving global health outcomes, particularly in low-income countries.
A large cross-sectional study of over 2,800 young men in Switzerland found an association between mobile phone use and lower sperm concentration. While no link was discovered to poor sperm motility or morphology, the results suggest that reduced semen quality may be linked to increased mobile phone usage.
Researchers found that fathers' reported symptoms of anxiety and depression were not associated with worse behavioral and cognitive outcomes in their children. In contrast, slightly higher levels of depressive symptoms among fathers during pregnancy were linked to fewer behavioral difficulties in their child at six to eight years old.
Researchers found that sperm flagellar waveforms are primarily influenced by viscosity rather than shear rate, promoting energy-efficient beating behavior. Sperm adjust their power generation to respond to fluid dynamics, enabling efficient swimming against the flow in high-viscosity media.
A recent meta-analysis found that women in low- and middle-income countries are disproportionately affected by obesity, with risks ranging from 2-3 times higher than men. This disparity is most pronounced in the Sub-Saharan region, where women are up to 10 times more likely to have obesity.
Researchers at the University of Arizona Health Sciences received a $13.1 million grant to study how to improve immune defense in older people. The goal is to create interventions that can help combat age-related decline in T cells, leading to better health outcomes and reduced healthcare expenses.
Researchers have genetically engineered mice with human-like ACE2 protein, allowing them to develop symptoms similar to young humans infected with COVID-19. This breakthrough model has the potential to study disease impact and treatment approaches more effectively.
Researchers will investigate the brain's signaling pathways when xylazine and fentanyl are used together, with the goal of identifying potential therapeutic targets. The study could lead to new strategies for treating individuals struggling with combined substance use.
Scientists identify pyroglutamination, a spontaneous chemical change, in peptide synthesis, leading to an amyloidal structure and potential implications for neurodegenerative diseases like Alzheimer's and Parkinson's. The process favors aggregation of molecules, forming plaques that interrupt neuronal flow.
Researchers introduce FragDPI, a novel method for predicting drug-protein binding affinity by merging sequence information of drugs and proteins. The model yields commendable outcomes compared to baselines, accurately identifying specific interaction parts of drug-target pairs.
Researchers found that cognitive decline quickened by 50% in the first year of the pandemic, with factors like loneliness, depression, and decreased exercise contributing to the impact. The study suggests that lockdowns had a lasting effect on brain health in people aged 50+, raising concerns about increased risk of dementia.
Researchers at Max Planck Institute of Molecular Physiology developed an innovative imaging technique to visualize the cardiac thick filament in its native environment. The resulting high-resolution image reveals new insights into the molecular organization and function of the sarcomere, a crucial component of heart muscle contraction.
A new classification system for heart attacks based on heart muscle damage is released, offering a more differentiated definition and improving understanding of acute atherothrombotic MI. This system has the potential to stratify risk more accurately and lay the groundwork for development of injury-stage-specific therapies.
Researchers at Boston University developed a new bedside cardiac assessment curriculum to improve patient-centered communication and medical training. The curriculum, called 'Listen Before You Auscultate,' uses an active-learning approach to teach students the skills needed for effective bedside care.
A collaborative study has developed an agarose spot migration assay to examine the ability of extracellular vesicles to attract other cells in a controlled environment. The assay revealed differences in EVs' recruitment capability for endothelial cells, particularly in highly metastatic cancer cells.
The American Heart Association statement proposes next-generation biomarkers for earlier detection of cardiometabolic risk factors in children, which can be influenced by heart-healthy nutrition and lifestyle factors. This could lead to better prevention and intervention strategies for obesity, diabetes, and heart disease.
Michele Starnini and colleagues studied two online communities on Reddit: GreatAwakening and FatPeopleHate. Despite deplatforming, these communities became more resilient due to their engaged members who migrated to Voat, a new platform.
Researchers developed a fast-charging hybrid battery system that combines electrochemical generation of formic acid with a microbial fuel cell, enabling efficient energy storage. The system produced enough current for 25 hours of discharge and demonstrated potential applications in monitoring water toxicity.
The Ghose lab will use the new SRM to study programmed cell death in tiny embryonic cells of the roundworm C. elegans. This technology will allow for finer detail and pinpoint documentation of cell death, advancing research on cell biology.
Researchers at the University of Adelaide have discovered a novel population of stem cells responsible for osteoarthritis progression. Treatment with fibroblast growth factor 18 (FGF18) stimulated cartilage recovery and reduced osteoarthritis, offering a potential pharmaceutical treatment to address the disease.
Researchers discovered that sunflowers don't rely on phototropin for heliotropism; instead, they exhibit a unique gene expression pattern when growing outdoors, suggesting multiple pathways for light-sensing and growth.
Research from Cornell University reveals that digitization can stimulate demand for physical copies, particularly for less popular books. The study found a strong 'discovery effect' driving increased sales, with book lovers often preferring physical books over digital versions.
Thyroid cancer incidence is significantly higher in more affluent areas of São Paulo State, Brazil, compared to less developed regions like Barretos. The study suggests overdiagnosis may be responsible for this trend, with mortality rates remaining similar across socioeconomic groups.
A recent study investigating the thermal response of temperate lakes to atmospheric warming found that local climate, land cover, geomorphology, and water transparency play significant roles in shaping lake responses. Clear, cold, and deep lakes are more responsive to warming, while those with nutrient pollution exhibit lower sensitivity.
A study led by the University of Sydney found that many antibiotics for childhood infections have less than 50% effectiveness, leading to thousands of unnecessary deaths globally. The World Health Organization has declared antimicrobial resistance a top public health threat, emphasizing the urgent need for updated guidelines.
Economic sociologist Oliver Nachtwey analyzes Silicon Valley speeches and articles to show the emergence of a new spirit of digital capitalism. Solutionism is prevalent among tech elites, but its impact on worker protections and democratic processes remains uncertain.
The BioRescue project evaluated 65 advanced assisted reproduction procedures in white rhinos, showing the technology is safe for donor females and yields successful embryo generation. Regular OPUs improve reproductive health in individual female rhinos.
Researchers at Rensselaer Polytechnic Institute found that frequency pictograms can induce optimism when presented in a sorted way. This could have implications for attribute framing in marketing and public policy. Sorted verses unsorted pictograms should be used strategically to make consumers feel favorably or negatively.
Researchers train AI to analyze data from over 100 cellular drug targets and their genetic variations. The algorithm predicts with more than 80% accuracy how cell surface receptors respond to drug-like molecules.
A research team has developed a new method for mapping brain activity to understand behavior changes in patients with neurological disease. The technique uses CaMPARI images to track brain activity and can be used to study the effects of Alzheimer's disease on brain function.
A national-level study found that the median UVC dwell time was 7 days, and CLABSI incidence did not differ significantly between 0-7 days and 7-15 days. The study also highlighted high rates of antibiotic exposure without reduction in CLABSI rates, emphasizing the need for nuanced approaches to antibiotic administration.
Researchers developed a novel wearable ECG patch with active dry electrodes that improves upon traditional Ag/AgCl electrodes by increasing user comfort, reducing skin irritation, and enhancing diagnostic accuracy. The compact and lightweight design enables continuous monitoring and remote sensing capabilities.
New studies show that giant gas planets in nearby star systems can prevent life on smaller, rocky planet neighbors by kicking them out of orbit and wreaking havoc on their climates. Researchers found that four giant planets in the HD 141399 system are likely to destroy the chances for life on Earth-like planets.
A new database containing thousands of solar mirror samples offers valuable insights into degradation trends over decades. The Solar Mirror Materials Database (SMMD) provides natural and accelerated exposure data for accelerating test development, design optimization, and manufacturing guidance.
Novel vaccine candidates using Computationally Optimized Broadly Reactive Antigens (COBRAs) protect against multiple influenza B strains, including those from different lineages. These vaccines show long-lasting protection, potentially reducing the need for yearly updates.
The study found that funding for supportive services is a significant hurdle, and innovative solutions are needed to secure reliable funding. Housing models with integrated services have proven popular among better-off individuals, but limited options remain for older people with fewer resources.
Researchers used transcription factors to stimulate production of specialized steroids in petunia, which are likely involved in plant defense. The discovery has significant potential for bioproduction of bioactive natural products in various plant families.
A study by Queen Mary University of London reveals that trust is the key factor in British South Asians' participation in genetic testing. Participants emphasize the importance of General Practitioners (GPs) as trustworthy professionals and personalized prescribing with genetic information to enhance trust and medication adherence.
Robust data supports face mask use to reduce SARS-CoV-2 transmission in community settings. The study recommends masks as part of future pandemic responses to respiratory viruses.
The DGIST Academy-research integration research team developed a new technology that can analyze high-speed electrons within thin components in extreme environments. This achievement was made possible through the systematic establishment of academy-research integration programs, enabling significant outcomes to emerge.
A new study in Nature Communications presents a large-scale chart of cognitive development in teens, revealing that executive function usually matures by 18 years old. The findings have significant implications for psychiatrists, neuroscientists, parents, educators, and the judicial system.
Researchers developed a new method to improve air quality models by assimilating sulphate reaction rates. This approach resulted in improved accuracy, reducing mean bias for SO4^2− and SO2 concentrations from -13.1 μg/m^3 to 3.5 μg/m^3 and 17.0 μg/m^3 to 6.3 μg/m^3 respectively.
A new study reveals that sunflowers use different molecular pathways to initiate and maintain tracking movements, involving multiple light signaling pathways. The research also found that depletion of one or more light triggers has little effect on the sunflower's ability to track the sun.
The Portuguese team TWIZ from NOVA School of Science and Technology secured 1st Place in the Alexa TaskBot Challenge 2 with a multimodal conversational agent. The winning team was led by João Magalhães and included CMU Portugal Affiliated Ph.D. students Diogo Tavares and Diogo Silva, who improved their visual interface as their biggest...
A new study led by University of Maryland Professor Sujay Kaushal reveals that human activities are making the planet's air, soil, and freshwater increasingly salty. This acceleration of the natural salt cycle poses an 'existential threat' to ecosystems and human health if current trends continue.
Researchers at Karolinska Institutet have discovered that a metabolic increase in the hippocampus is an early indicator of Alzheimer's disease. The study found that changes in mitochondrial metabolism precede synaptic disorganization and impaired autophagy, highlighting potential new methods for early intervention.
A recent study by Durham University suggests that graphic warning labels on meat options could reduce people's meat consumption, improving public health and reducing the UK's carbon footprint. The labels, which show a graphic image alongside text, were found to be effective at discouraging people from choosing meals with meat.
A team of researchers, led by L. Mahadevan, combines physics and machine learning to create a 3D printing technique inspired by Jackson Pollock's drip painting method. They can quickly create complex shapes with the new technique, which harnesses fluid instability for accurate print creation.
NYU Tandon's new 3D video technology is being used to enhance dance education by allowing students to learn techniques and choreography from various angles and distances. The project aims to make Point-Cloud Video suitable for streaming on standard devices, reducing bandwidth consumption and increasing accessibility.
A new diagnostic tool has been developed to help diagnose tuberculosis in children, with a focus on providing accurate results quickly and conveniently. The tool uses blood samples taken from the fingertip and identifies specific gene activity to detect the disease, offering improved accuracy compared to traditional methods.
Researchers discovered that D. sechellia's nervous system has evolved to tolerate the toxins in noni fatty acids, allowing it to prefer and lay eggs on the fruit. The study reveals differences in taste sensitivities among three closely related fly species, providing insights into how insects adapt to host plants.
Researchers used AI to identify 2 promising antigens as candidates for a gonorrhea vaccine, which accurately predicted reduction of bacterial populations. The antigens were tested in lab and animal models, showing efficacy in killing bacteria and decreasing bacterial burden.
Researchers found a total of 4,721 proteins altered with age in the murine ovary, including upregulated ECM proteins associated with fibrosis. Age-dependent changes also affect immune response pathways and unique immune cell populations.