Physicists at the University of Bonn have experimentally proven the applicability of the fluctuation-dissipation theorem to Bose-Einstein condensates made of photons. The study reveals a direct relationship between fluctuation and sensitivity, enabling precise temperature determination in complex photonic systems.
Researchers identify vulnerable cell populations in the striatum, which contributes to loss of motor control and early mood disorders. Damage to striosomes may be responsible for mood disorders, while degeneration of matrix neurons likely contributes to motor decline.
The University of Kansas has received a five-year, $2.9 million grant to continue its work supporting Kansans with disabilities and their families. The grant will fund the core activities of the Kansas University Center on Developmental Disabilities, including research, community service, training, and education.
A phase 3 trial found that adding nab-paclitaxel to a standard gemcitabine plus cisplatin regimen did not significantly extend median overall survival for patients with advanced biliary tract cancers, but provided benefits for subsets of patients. The treatment also showed improved response rates and progression-free survival times.
Researchers at Children's Hospital of Philadelphia developed ESPRESSO, a new computational tool that can accurately discover and quantify RNA molecules from error-prone long-read RNA sequencing data. This will enable better diagnosis of rare genetic diseases and discovery of potential therapeutic targets in cancer.
A recent study published in Science Advances has deepened the understanding of circadian rhythm regulation in mammals. The research found that intracellular cyclic adenosine monophosphate (cAMP) is controlled by a neural network, whereas calcium ions are regulated by intracellular mechanisms.
Researchers at Okayama University have identified cycloartenyl ferulate as the main contributor to brown rice's health-promoting effects. The compound's antioxidant properties help protect cells from oxidative stress and inflammation, leading to benefits such as weight reduction and improved cholesterol levels.
A team of researchers from Japan has developed a single purely organic neutral molecule with an incomplete oxidation state for the first time. The new molecule exhibits multi-step phase transitions and crossover caused by intra- and intermolecular electronic interactions, leading to unique strongly correlated electron properties.
Researchers have created a technique that enables visualization of the retina and choroid with high resolution at distinct depths, revealing new insights into eye structure. The technology, called STOC-T, makes it possible to image all primary layers of the choroid for the first time.
A new study reveals that transient wind events trigger significant phytoplankton blooms near tropical reef islands, creating a large network of marine ecosystems. This process, driven by coastal winds, fuels the production of phytoplankton and supports critical feeding habitats for migratory marine species.
Scientists have discovered a quadratic relationship between the coefficient of T-linear resistivity and transition temperature in FeSe, indicating that spin fluctuations may play a common role in unconventional superconductors. This finding provides insight into high-temperature superconductivity.
A recent study found that DNA from domesticated chickens has been introgressing into the genomes of wild red junglefowl, leading to a loss of genetic diversity. The researchers estimate that wild birds have inherited 20-50% of their genomes from domestic chickens, which could make them less resilient to environmental changes.
A new American Heart Association scientific statement emphasizes the importance of rapid evaluation for TIA, which can lead to full-blown stroke. The statement offers a standardized approach to evaluating people with suspected TIA, including guidance for hospitals in rural areas with limited resources.
Lithium niobate (LN) is being developed to harness its exceptional properties for diverse future applications. LN photonic chips can transform industries beyond optical fibre communications by detecting signals in the infrared part of the spectrum.
A new study conducted at the University of Turku found that maternal gestational diabetes mellitus may have unfavourable effects on the neurodevelopment of 2-year-old children. A healthy diet during pregnancy supports child's neurodevelopment, while higher maternal body fat percentage is associated with weaker cognitive and motor skills.
A research team from the University of Southampton discovered that supermassive black holes are fueled by gas clouds from neighboring galaxies. The study found a link between misaligned gas and active supermassive black hole activity, suggesting that galaxy interactions provide a source of fuel for these phenomena.
Researchers found a link between astrocytes from schizophrenic patients and reduced vascularization in the brain, which may contribute to the disease's metabolic flux. The study suggests that astrocytes could be a target for novel therapies to address schizophrenia.
Researchers found that Sirtuin 7 regulates brown adipose tissue functions, leading to suppressed energy expenditure and thermogenesis. The study reveals a molecular pathway involving protein deacylation and mRNA binding, which will have implications for treating hypermetabolic conditions like cancer and obesity.
Scientists at Cold Spring Harbor Laboratory have found a way to reprogram cells causing Ewing sarcoma to behave like normal connective tissue cells. By blocking the protein ETV6, cancer cells can be forced to take on a new identity and grow less aggressively.
Researchers analyzed over 600 genome sequences to chart the complex history of Y. pestis, the bacterium that causes plague. They found an unstable molecular clock and identified five populations throughout history, including ancient pandemic lineages.
Researchers at the University of Wisconsin-Madison have developed a machine-learning model that detects cancers at an early stage by analyzing fragments of cell-free DNA in plasma. The technique, which uses readily available lab materials, distinguished people with any stage of cancer from healthy individuals 91% of the time.
Researchers at Beckman Institute for Advanced Science and Technology will use a unique combination of MRI and mass spectrometry imaging techniques to study Alzheimer's disease on an unprecedented scale. By capturing detailed chemical information, they aim to understand the molecular-level changes that occur in aging brains and develop ...
Researchers at UC San Diego describe how pancreatic cancer stem cells leverage SMARCD3, a protein that normally suppresses tumors, to boost resistance to treatments and drive growth. Deleting SMARCD3 reduces tumor growth and improves survival rates.
The CABBI team successfully demonstrated precision gene editing in miscanthus, a promising perennial crop for sustainable bioenergy production. The results will accelerate efforts to tap the huge potential of this highly productive but genetically complex grass as a source for biofuels, renewable bioproducts, and carbon sequestration.
A Canadian-led research team has discovered how the protein PCSK9 degrades LDL receptors, leading to increased cholesterol levels. HLA-C plays a critical role in this process, which could lead to new treatments for cardiovascular diseases and certain cancers.
Researchers have identified the genetic secrets behind skullcap's anti-cancer activity, enabling the production of synthetic compounds. The discovery is expected to lead to more sustainable and rapid synthesis of cancer-fighting molecules.
A new paper by a University of Illinois legal scholar suggests that California's CalRx Biosimilar Insulin Initiative could lower insulin prices, saving uninsured patients up to $4,000 per year. The proposal faces regulatory and logistical challenges, including FDA approval and state budgeting issues.
Researchers at Tohoku University developed a microelectronic fiber that can analyze electrolytes and metabolites in sweat, enabling wearable bioelectronics for monitoring biochemical signatures. The breakthrough smart fabric has the potential to provide greater versatility in functions, larger sensing areas, and greater comfort.
Biomarkers of bone turnover are essential for diagnosing and treating metabolic musculoskeletal diseases. The International Osteoporosis Foundation, IFCC, and ESCEO have collaborated to publish authoritative reviews on the use and interpretation of these biomarkers.
A survey of 1,034 people found that most believe insects can be a sustainable source of protein in the future. Key factors improving acceptance include preparation methods and information on insect potential as a food source.
Researchers developed a novel strategy to engineer root nodule symbiosis in legumes and cereals using nanobodies. This approach, tested in barley and Lotus plants, initiates nodulation by bringing receptors together, revealing the core complex involved in symbiotic signaling.
Purdue University researchers employ a cellular signal processing system to analyze the migration of cancer cells, identifying the impact of chemical cues and fluid flow on cell movement. The study's findings have significant implications for understanding cancer metastasis and the development of more effective treatments.
Researchers at HKUST mapped out the fundamental mechanisms of C.elegans Microprocessor (cMP), revealing its distinctive molecular mechanism. The study suggests that cMP's two subunits, cDrosha and Pasha, determine cleavage sites using distinct methods, differing from human MP in multiple aspects.
Researchers successfully tested a real-time coherent transceiver prototype for continuous sensing over a 524-km long aerial fiber network. The approach uses information extracted from coherent digital signal processing to monitor polarization changes, enabling environmental and network sensing.
A new study found that sunrise and sunset trigger significant boosts in people's feelings of awe, improving mood and positive social behavior. Participants were willing to pay a premium to experience these phenomena, highlighting their potential value in boosting wellbeing.
Researchers connected global climate modeling with local hydrological data to improve water flow models. They found that using smaller tree samples and younger trees yielded better model validation results.
Researchers have designed a treatment that uses a modified bacterium to target and dissolve biofilms caused by Pseudomonas aeruginosa, a leading cause of hospital mortality. The treatment has shown significant efficacy in mice, reducing lung infections and doubling survival rates.
A worldwide Citizen Science project has collected data on light pollution over eleven years, revealing a faster decline in star visibility than previously thought. The rate of change is attributed to increased sky brightness, with dramatic consequences for stargazing and astronomy.
A new Lancet Series argues that a 'One Health' approach is needed to prevent, monitor, and respond to public health emergencies globally. The series calls for greater investment in preventive and preparedness interventions, as well as greater representation of environmental organisations.
Researchers have found evidence that high frequency brain waves in the motor cortex contain information about planned movements, providing a new understanding of how the brain controls movement. The study's findings could inform the development of brain-machine interfaces and reveal new insights into cortical function.
Researchers at the University of Córdoba found that silicon fertilization increases olive trees' tolerance to biotic and abiotic stresses. The ideal dose is 20 mg/liter, and application methods include foliar treatment and soil irrigation.
Researchers found SARS-CoV-2 virus in almost all plane wastewater at three UK airports during a period of COVID restrictions. The study suggests that wastewater testing could be used to monitor the general health of passengers on flights entering the country, potentially capturing 8-14% of SARS-CoV-2 cases.
A recent study found that patients who met with surgeons for first-time surgery consultations via telemedicine were satisfied with the quality of communication, comparable to in-person visits. The study suggests that either method is appropriate, depending on what the surgeon and patient prefer.
Researchers found that rephrasing original questions and using bot-specific wording significantly improved resolution rates. Upskilling individuals to effectively interact with chatbots can help bridge the digital divide.
The Chinese Academy of Sciences is reorganizing its institutes into four categories to focus on basic research, applied science, and regional development. However, concentrating resources on creating centers of big-science research infrastructure may bring more distinct competitiveness to the CAS.
Researchers discovered that baboons employ an efficient strategy to transition from quadrupedal to bipedal walking by 'crouching' their hindlimbs and 'sprinting' them forward under their torso. This process enables the animals to maintain a natural gait while standing upright, requiring minimal energy expenditure.
Researchers developed the Functional Assessment of Cancer Therapy – Radionuclide Therapy (FACT-RNT) questionnaire to identify key symptoms and side effects associated with radionuclide therapy. The tool aims to improve patient-centered care and guide treatment decisions for prostate cancer patients.
A recent study from UW's Center for Healthy Minds found that COVID-19's impact on K-12 schooling took a toll on educators' mental health, with 78% reporting clinically meaningful anxiety symptoms. Meditation-based interventions showed promise in reducing symptoms of anxiety and depression among school system employees.
Researchers believe microalgae could be a new kind of superfood due to its high protein and nutrition content. Algae can produce 167 times more biomass than corn annually while using the same amount of land, making it a more efficient food source.
A new study in Scientific Reports identifies four genes associated with whales' massive size, including GHSR, IGFBP7, NCAPG, and PLAG1. These genes promote large body sizes while mitigating potential drawbacks like increased cancer risk.
Women with cancer suffer accelerated physical function declines post-diagnosis and years later compared to age-matched controls. Supportive interventions are crucial for preserving physical functioning in these patients.
A new study by Globe at Night reveals that artificial lighting is dulling the night sky more rapidly than satellite measurements indicate. The loss of visible stars has alarming implications for human health and wildlife.
Researchers at the University of Essex have developed a new technique that uses non-invasive brain wave monitoring to accurately identify the music someone is listening to. The method has been successfully tested on a dataset of simple piano music and shows promise for decoding language signals from the brain in the future.
Scientists propose an 'essential use approach' to eliminate harmful chemicals from daily use and exposure, benefiting public health and the environment. This approach advocates for restricting the use of chemicals only where necessary for health or societal functioning, with feasible alternatives available.
In a new study, red squirrels that gamble with their reproductive strategy outperform those that play it safe, especially during mast years. Despite short-term costs, female squirrels that increase litter sizes in low-food years experience greater lifetime fitness if they get to experience a mast year.
Fire ants exhibit activity cycles and waves that propagate upwards in high-density conditions, driven by social attraction and collective motion. The study reveals the importance of density in determining these behaviors, which are similar to those observed in flocks of birds and schools of fish.
Researchers at UW-Madison developed silica nanocapsules that can carry CRISPR tools across the blood-brain barrier, enabling brain-wide gene editing for disorders like Alzheimer's and Parkinson's. The technology has potential for non-invasive delivery of gene therapies.
A Dartmouth-led study found that team-based coaching significantly improves the risk of acquiring post-procedural acute kidney injury (AKI) when compared to other interventions. The Collaborative with Surveillance intervention reduced the odds of AKI by 46 percent, making it a promising approach to address this prevalent adverse event.
Researchers developed a technique that introduces a phosphonic acid-functionalized fullerene derivative and a redox-active radical polymer to strengthen the perovskite crystal structure and increase conductivity. This approach improved the stability of perovskite solar cells, achieving efficiencies comparable to traditional solar cells.
Researchers found that metabolite changes were most evident in ripe fruit, with nitrogen deficiency increasing some compounds and phosphorus deficiency decreasing diversity. Salinity threshold above which metabolites change was identified, which could impact harvested pepper resistance to pathogens.