A post-hoc analysis of the ASPREE trial found that low-dose aspirin was associated with a 20% increased incidence of anemia and decline in ferritin levels in healthy older adults. The study recommends periodic monitoring of hemoglobin for patients taking aspirin.
Researchers have reconstructed the face of a 16-year-old woman buried near Cambridge with an incredibly rare gold and garnet cross, revealing she moved to England from Central Europe as a young girl. Analysis shows that her diet changed significantly after arrival, indicating a short and challenging life.
Researchers found that probiotics help preterm babies achieve a balanced gut microbiome and eradicate harmful bacteria. The study also shows that probiotic-supplemented preterm newborns have lower risk of carrying antimicrobial resistant bugs despite frequent antibiotic treatment.
A new gene variant, RBL1, has been identified in a type of rice that can be modified to improve performance without yield penalties. This breakthrough could lead to more disease-resistant rice crops with high yields, addressing a major threat to the industry and meeting growing global demand.
A comprehensive dataset of neurotransmitter receptors has been made publicly available, revealing potential role in distinguishing internal thoughts and emotions from external influences. The study's findings have exciting implications for understanding brain function and developing new treatments.
Researchers have identified and fabricated a new electrocatalyst using theoretical predictions, significantly improving the oxygen evolution reaction. The discovery uses cerium-doped cobalt oxide to achieve an overpotential of only 261 mV at 10 mA cm−2, outperforming individual cobalt oxide.
A supersized database of over 45,000 traits tracks the behavior, distribution, and life patterns of fruit eaters and birds in Central and South America. The Frugivoria database provides crucial insights into their role in maintaining forest composition and health.
A recent study found a positive association between short-term exposure to fine particulate matter (PM2.5) and increased hospital admissions, length of stays, and associated costs in all major diseases. The study's findings suggest that improved air quality since 2013 saved CNY2.28 billion in medical expenses in 2017.
Researchers link Kawasaki disease to ultrafine aerosols rich in metals from intensive farming and urban pollution. Exposure to high levels of metals is associated with increased incidence of the disease.
A new study analyzing data from the ASPREE trial found that prolonged daily aspirin use increases the risk of anaemia by 20 per cent in people mostly aged 70 and over. Regular monitoring for anaemia should be considered for older adults taking low-dose aspirin.
Researchers have discovered anomalous quantum oscillations in twisted double bilayer graphene, which exhibit periodic behavior with the inverse of magnetic field. The oscillations are tunable by electric field and qualitatively reproduce calculations based on a phenomenological model.
Researchers discovered a new mechanism by which senescent cells resist redox stress, involving the hyperoxidation of peroxiredoxin 2, leading to decreased sensor activity and reduced RRC. This finding offers insights into aging and proposes delaying RRR as an effective strategy to intervene in aging.
Studies found that transport stress can cause weight loss, immunity damage, and reduced productivity in animals. The enteric nervous system plays a key role in regulating the effects of transport stress on intestinal health.
Astronomers have proposed a new method for measuring the distances of galaxies, utilizing double-period RR Lyrae (RR Lyr) stars. The study, published in Nature Astronomy, aims to improve the accuracy of distance measurements by leveraging the unique properties of these stars.
A Cambridge expert argues that politicians' neglect of evidence hampers plans to tackle health and climate change in the UK. The expert suggests two changes could mitigate this issue: engaging citizens more in policy-making and increasing politician accountability through legally binding systems.
The article discusses the growing challenge of food security in Africa, particularly with regards to rice production and consumption. The research reveals that socioeconomic developments have a more substantial influence on rice availability than gradual climate change, but climatic anomalies pose a significant threat to stability. Div...
Researchers developed Genome Architecture Mapping (GAM) to study DNA interactions, revealing novel three-dimensional configurations that were invisible to Hi-C. This technique provides a more comprehensive understanding of genome organization and its impact on health and disease.
A new research group led by Zoltan Nagy is working to understand megakaryocyte development and maturation. The team will use single-cell RNA sequencing to identify key factors controlling platelet production, with the goal of improving platelet counts for transfusions.
A study found that more than 60% of female first authors are not included as inventors on patents, while male first authors have a higher inclusion rate. The research highlights a gender gap in patent inclusion, with senior female authors also underrepresented.
Researchers from Complexity Science Hub highlight similarities in models used by economists and physicists to analyze financial markets. The study aims to create an overview of these models, promoting interdisciplinary collaboration and avoiding research that gets lost in translation.
A new study introduces a minCluster portfolio optimization method specifically designed for highly volatile markets, including cryptocurrencies. The method consistently outperforms traditional approaches and considers downside risk to find the best asset allocation.
The Great Sitkin Volcano in Alaska has two magma chambers that drive its long-lived and explosive eruptions. Scientists have discovered a six-stage eruption cycle, with the interaction between the chambers contributing to lava effusion. This study helps predict volcanic eruptions and assess hazards.
Researchers in China have developed a new NMR-based wettability index for rocks, utilizing magnetic susceptibility contrast and internal gradient measurements. This method enables accurate assessment of wettability in complex reservoirs like tight oil and shale oil formations.
The PanDrugs2 programme analyzes alterations in tumour genes, relates them to existing available drugs, and reports on the most suitable ones. It handles data on over 4,600 genes and 14,600 chemical compounds, generating information on around 74,000 associations between drugs and genes.
Researchers at Cornell University have developed a novel strategy for making recyclable polyolefins by introducing masked double bonds, known as 'Trojan horse' functional groups. These polymers can be chemically deconstructed and re-polymerized without losing quality.
A recent study suggests that songs with high energy and positive emotions are more likely to match prevailing weather conditions, influencing listener preferences. The research found a strong association between energetic and positive music and warm and sunny weather, but only for popular songs.
The UK is investing £11 million to improve forecast accuracy for extreme weather events like storms, floods and droughts. Scientists are focusing on atmospheric turbulence to create more detailed models.
A new study from the University of Eastern Finland explores how digital-based start-ups can leverage digital artifacts for early and rapid internationalisation. The research model provides a toolkit to identify opportunities for companies to adapt their digital services to international markets.
A new study published in Sleep Health found that habitual daytime napping is associated with a larger total brain volume, a marker of good brain health linked to lower risk of dementia and other diseases. The research team used Mendelian randomisation to establish a causal link between napping and brain health.
Researchers used cryo-electron tomography to study the dynein motor protein, revealing new details about how it generates force and coordinates with other proteins. This knowledge may help develop treatments for diseases related to cilia dysfunction, such as fertility issues and lung disease.
A study by climate experts reveals that while some aspects of sea level rise risk assessment have improved, others remain imperfect, particularly in conveying 'unquantifiable' uncertainties. Improvements in language and graphics are being incorporated into climate reports, informing civic leaders to counter rising seas effects.
Scientists at the University of Cambridge have developed a solar-powered reactor that captures CO2 from industrial processes or directly from the air and converts it into sustainable fuels. The technology also uses plastic waste, converting it into glycolic acid and other valuable chemical products.
Researchers employ DFT and NEST analysis to investigate pyrrolidinyl gold(I) complexes, revealing enhanced understanding of electronic and steric effects. The findings facilitate the design of novel chiral ligands for enantioselective reactions.
A McMaster University study found that cognitive behavioral therapy (CBT) for new mothers can lead to adaptive changes in infant brain functioning and reduce post-partum depression symptoms. The study tracked 73 pairs of mothers and babies undergoing PPD treatments between 2018 and 2020.
Researchers found female babies with CDH have a 32% higher risk of dying within 30 to 60 days of birth compared to males. The study, using medical records from an international registry, suggests that lower birth weights for females may be linked to the disparity in survival rates.
Researchers developed a novel method using nucleoside analogs to label and sequence messenger RNA, allowing for the tracking of dynamic changes in cellular gene expression. This approach enables researchers to investigate transcripts over time and gain insights into cellular biological processes.
Scientists at the University of Copenhagen discovered a new type of fat cell called SWAT cells that provide structural integrity to adipose tissue. These flexible cells can differentiate into various types, including fat cells and progenitor cells, suggesting a crucial role in adapting to metabolic conditions.
Research at Umeå University reveals unique muscle fibers in extraocular muscles are resistant to ALS and increase in proportion when other fibers decrease. This finding could lead to new treatment strategies for slowing down the disease.
A study by Lund University researchers discovered that predatory bacteria, like Bdellovibrio, grew in number and consumed other bacteria when chlorine was removed from drinking water. This finding suggests that efficient filtration systems can reduce the need for chlorine, offering hope for a chlorine-free future.
Researchers at the University of Ottawa have invented a method to create better molecule-based magnets, enabling high-density storage and processing capabilities. The breakthrough discovery involves a two-coordinate lanthanide complex with intrinsic magnet-like properties.
Scientists at University of Konstanz have developed a method to compress an electron beam into short pulses using femtosecond light flashes. The resulting electron pulses exhibit temporal superposition and can be used to study ultrafast phenomena in quantum mechanics, including the interaction between electrons and light.
Researchers mapped receptor densities across the cortex, identifying two main arrangements that align with functional systems. The findings provide insights into how the brain adapts to a changing world, with potential applications for computational models and neuroscientific research.
Finnish older golfers experience significant increases in physical activity levels, including moderate exercise and walking. Quality of life also remains high, with over 90% reporting good well-being during the pandemic.
Researchers at Tsinghua University Press have synthesized a new silver-molybdate nanocluster with the help of thiolate and phosphine ligands to increase stability and uniformity. The use of protective ligands opens the door to isolating novel structures with diverse properties.
A new study finds that de facto decriminalization of drug possession in Baltimore led to significant reductions in low-level drug-related arrests, mainly among the Black community. However, racial disparities persisted, with the ratio of street arrests in Black residents increasing after the policy change.
Researchers found that leukemia cells use messenger particles to navigate and release molecular cargo at distant sites, driving cancer metastasis. A potential therapeutic strategy involves targeting these particles with an antibody drug that blocks E-selectin activity.
Researchers at Rensselaer Polytechnic Institute found that women are more likely to hide their LGBTQ+ affiliation when they expect discrimination against LGBTQ+ individuals. This behavior is linked to the experience of gender-based discrimination and the expectation of unequal treatment.
Researchers have developed a new method to control the movement of individual DNA molecules through a nanopore, allowing for higher accuracy in sequencing and analysis. This breakthrough has the potential to improve diagnostic and sequencing applications, including peptide sequencing.
Researchers from KIT developed a new strategy for producing highly efficient and stable deep-blue organic light-emitting diodes. The new molecule exhibits dual-channel intra-/intermolecular exciplex emission, resulting in high external quantum efficiency of 20.35% and luminance of 5000 cd/m2.
Fossil evidence confirms that long-necked marine reptiles like Tanystropheus were vulnerable to predation. Researchers found bite marks on two specimens with severed necks, suggesting they were decapitated during a violent event.
Teleost fishes have developed distinct ways to generate heat, with mackerel tuna utilizing muscle differentiation and sailfish relying on ATP decomposition. These findings suggest that organisms adapt to achieve endothermy through different pathways, maximizing existing biological foundations.
A new study reveals that neurons expressing steroidogenic factor 1 (SF1) influence inflammation in white and brown adipose tissue. SF1 neurons help suppress inflammatory responses in inguinal WAT, but not in epididymal WAT, and activate thermogenic activity in BAT.
Scientists have discovered that dimethylfumarate can block blood clotting during infection, potentially treating life-threatening DIC and severe COVID-19. The mechanism involves blocking interferon production, which promotes tissue factor releases.
Researchers discovered a probiotic that can convert toxic mercury into less harmful forms, reducing neurological damage and improving iron absorption. The probiotic uses genes from a resistant bacteria to detoxify methylmercury, a neurotoxin found in fish-based diets.
A study examined the seismic performance of 12 hospitals in Turkey's southcentral region, finding that base-isolated structures performed better than fixed-base ones during the 2023 earthquakes. The report provides valuable insights for policymakers and engineers to enhance hospital resilience and disaster response strategies.
A new study tracking 554 UK undergraduates from May 2020 to May 2021 found high levels of psychological distress and anxiety during the pandemic. Students reported significantly lower wellbeing, happiness, and life satisfaction compared to pre-pandemic levels.
A communication robot is being developed to prevent elderly isolation by facilitating self-disclosure through different communication options. The study found that the most appropriate option depends on the recipient, message content, and sender's gender and personality traits, reducing participants' anxiety in self-disclosure.
Researchers at USTC developed a high-performance cellulose-based nanopaper with excellent mechanical and electrical insulating properties under extreme conditions. The material exhibits high tensile strength, toughness, and electric breakdown strength, making it suitable for protecting equipment in harsh environments.
A Singapore study found that COVID-19 vaccination remained effective against Omicron BA.4/BA.5 and XBB infections in children and adolescents. Vaccination before the first infection provided the highest immunity, with protection levels reaching up to 85.3%.
Researchers found that individuals with AUD displayed less impairment on fine motor and cognitive tasks when consuming a standard dose of alcohol, but showed significant impairment at a higher dose. This suggests that the physical effects of alcohol accumulation contribute to impaired performance beyond mere tolerance.