New research from Cold Spring Harbor Laboratory explores how adult brains adapt through critical periods of learning, such as caring for young. MECP2 dysfunction causes neurodevelopmental disorder Rett syndrome, but the study finds that brain circuits can be rapidly rewired in adults.
A recent study by Northumbria University reveals that firms with LGBT CEOs are substantially underestimated and undervalued on the stock market. The researchers found that such companies outperform the market by 0.69%-1.08% per month, making them a hidden gem of an investment opportunity.
A study by the University of Exeter found that hot weather reduces workers' productivity even in climate-controlled factories. Productivity dropped by 0.83% for every 1°C increase in outdoor temperature, resulting in a worker producing 22.6 to 33.4 fewer wafers.
The Second International Consensus Report on Precision Diabetes Medicine addresses the need for personalized approaches in diabetes care. The report highlights the potential of precision medicine to improve prevention and treatment outcomes by accounting for disease heterogeneity.
Researchers developed a novel approach to predict therapeutic targets for aging and age-related diseases. They trained a domain-specific BioGPT model on biomedical literature, which improved its performance in identifying prospective targets.
The estimated ADHD prevalence among children and adolescents in the US was 10.08% to 10.47% from 2017 to 2022, similar to previous estimates. No significant annual change in prevalence was found during this period.
Researchers analyzed UK data to identify patterns of illnesses in individuals leading up to a type 2 diabetes diagnosis. High blood pressure, respiratory tract infections, heart conditions, and asthma were commonly observed, suggesting earlier diagnosis may be possible.
A new method using big data and AI models the interactions of entire ecological communities across continents, revealing patterns of biodiversity. The collaboration between Cornell Lab of Ornithology and Cornell Institute for Computational Sustainability provides vital information for conservation efforts.
A recent University of Helsinki study reveals that bird communities inside and outside protected areas are converging due to climate change, posing challenges for conservation. Southern species are accelerating community-level change, spreading northward in search of suitable climates.
Researchers developed a software that can accurately detect intricate details of emotions in parents, even in everyday family life. The study uses machine learning techniques to analyze facial expressions from videos taken at home, providing potential early intervention opportunities for mood and mental health disorders.
A team of researchers has developed a stable, long-lasting superhydrophobic surface with a plastron that can last for months underwater. The surface repels blood and prevents the adhesion of marine organisms, making it valuable for biomedical applications such as reducing infection after surgery.
A substantial burden of RSV-associated hospitalizations was found in Canadian pediatric hospitals, especially among infants under six months. The study suggests that preventive strategies for these young infants could lead to decreased RSV disease burden in children.
A genome-wide association study reveals 34 genes potentially involved in choosing a vegetarian diet, including those related to lipid metabolism and brain function. The findings suggest that genetics play a role in the ability to subsist on a vegetarian diet.
Researchers have identified a crucial host protein, SND1, that plays a key role in SARS-CoV-2 replication. The virus uses its own protein NSP9 as a primer for RNA synthesis, which is facilitated by SND1 binding to negative-sense viral RNA.
X- and y-type thioredoxins play a crucial role in maintaining the redox balance of photosynthesis during fluctuating light conditions. The study found that these proteins facilitate electron transport through the electron transport chain, preventing photoinhibition and promoting plant growth.
Simultaneous large wildfires will become more frequent in the Western United States due to climate change, putting a strain on firefighting efforts. The study found that peak seasons for simultaneous blazes could be several weeks longer by the end of the century, affecting resource allocation and prevention strategies.
Researchers at Chalmers University of Technology have shown that graphene oxide nanoflakes can reduce the accumulation of misfolded amyloid peptides in yeast cells, which are similar to human neurons affected by Alzheimer's disease. This suggests that graphene oxide may hold great potential for treating neurodegenerative diseases.
A new pilot study at the University of Illinois Chicago found that 30% of new dads screened positive for postpartum depression, highlighting the importance of asking new dads about their mental health. The researchers believe that addressing fathers' health can be a powerful untapped tool in improving maternal health.
The University of Missouri's Missouri Work Zone Safety Center of Excellence aims to reduce fatalities and serious injuries in highway work zones through research and outreach. The center will focus on integrating emerging technologies, data analysis, and countermeasures to address distracted driving and other safety concerns.
Researchers at the University of Vienna discovered that domestic cats can produce low-pitched purring sounds without cyclical neural input. This finding contradicts previous theories and suggests a more complex brain-body connection in cat vocalization.
The Australian Long COVID services lack several categories, including early investigation, accessibility, and trustworthy public health information. Researchers propose building a response on US and UK guidelines that prioritize early detection, mental health support, and referral to multidisciplinary clinics.
A new study using wastewater surveillance has predicted the start of the annual RSV season 12 days early, allowing hospitals to prepare and allocate resources effectively. The study used real-time wastewater measurements to forecast the surge in pediatric RSV cases, providing a population-level early warning signal for the community.
A new study has identified commonly prescribed antibiotic, antipsychotic and prokinetic drugs as being associated with a higher risk of sudden cardiac arrest (SCA) in individuals with type 2 diabetes. Low fasting blood sugar levels are also linked to SCA, a leading cause of death.
The new research project examines the associations between relationship events and partners' personalities, focusing on socialization effects. Couples will be asked about their everyday lives to understand how situations evolve.
A new analysis estimates that switching all pet dogs and cats to vegan diets could spare nearly 2 billion land-based livestock animals yearly in the US, and nearly 7 billion globally. This could lead to significant reductions in environmental impacts such as land use, water consumption, and greenhouse gas emissions.
A large-scale clinical study confirms the validity of the Vienna Prediction Model in identifying low-risk patients with venous thromboembolism who may not require long-term blood thinning. The model's accuracy was found to be 5.2% after one year for patients with a low relapse risk, but adjustments were made to correct imprecision.
Researchers from Imperial College London and the University of Nottingham used machine learning to identify 'atomic shapes' that form basic pieces of geometry in higher dimensions. The findings reveal unexpected patterns in these shapes and demonstrate the potential for machine learning to accelerate mathematical discoveries.
Researchers at Tohoku University have developed a model predicting torque generated from electrical stimulation in stick insect leg muscles, allowing for precise control of insect movement. The study's findings have the potential to refine motor control of tuned biohybrid robots and enable adaptable devices with various applications.
Researchers studied how insects evolved two distinct flight strategies using robots and biophysicists. They found that asynchronous flight evolved together in a common ancestor, but some groups reverted back to synchronous flight.
A new study from the University of Michigan found significant racial disparities in preparedness for aging in place, with 40% of older Black adults living with a disability. Researchers highlight factors such as income, disability status, and household composition that negatively impact minority aging.
Researchers at Wake Forest Institute for Regenerative Medicine successfully created full thickness human bioprinted skin, promoting quicker healing and more naturally appearing outcomes. The bioprinted skin facilitated human-like skin architecture in vivo, with improved wound closure, reduced scarring, and enhanced tissue formation.
Researchers from CHOP and the University of Pennsylvania found that teenagers living in lower-income areas are up to four times less likely to complete driver training and obtain their license before age 18. Long travel times to driving schools also impacted enrollment, affecting those from both high- and low-income areas.
Researchers present a groundbreaking approach to create detailed neuronal models that can represent individual cells or predefined types, offering insights into biophysical properties and generalizability. The workflow uses evolutionary algorithms and open-source tools to optimize model parameters and achieve high similarity scores.
A new study aims to identify environmental and social factors contributing to Alzheimer's disease in older Black adults, who are up to two times more likely to develop the condition. Using remote cognitive assessments and biomarkers, researchers hope to gain a better understanding of the biopsychosocial factors behind this disparity.
Researchers discovered NKG2A receptors as potential targets to overcome immunotherapy resistance in breast cancer, offering a promising approach for treating immunotherapy-resistant triple-negative breast cancer patients.
A research team at Heinrich-Heine University Düsseldorf identified a key gene and molecular mechanism that determine the sex of honeybees. The process is similar to a game involving two dice, where different protein variants activate a molecular switch for female development.
Researchers classify UGDH as a molecular indicator of tumor progression in multiple cancer types, describing its involvement in key canonical cancer signaling pathways. Methods to inhibit UGDH and its downstream products are also identified.
Researchers at Utrecht University have uncovered a sophisticated mechanism by which coronavirus spike proteins can be activated for cell entry. Sugar binding induces opening of the spike protein and exposure of the receptor binding domain, required for subsequent entry steps.
A recent study found that Black adolescents are underrepresented in suicide research, with only 13% inclusion rate. Another study suggests cultural consensus modeling can elevate Black youth's voices and improve prevention strategies.
University of Copenhagen scientists have successfully produced plant-based cheeses with firm texture and improved aroma profile using natural fermentation processes. The study explores the potential of fermentation to develop flavor and texture in non-dairy cheese, paving the way for a more sustainable dairy-free alternative.
Researchers propose MXene and MBene compounds for capturing carbon dioxide from the atmosphere, leveraging their high selectivity and mechanical stability. These two-dimensional materials can be engineered to selectively capture CO2, offering a potential solution to curb global warming.
Researchers discovered that insects evolved ultrafast flight from a single common ancestor, with asynchronous beating and synchronous activation modes. They used physics models and robotics to test how these transitions could occur, finding that evolution can turn on and off this particular mode of flight.
A new study by the University of Göttingen reveals that oil palms' photosynthesis and response to meteorological and soil conditions play a significant role in N2O production. The research suggests that conventional measurement approaches can underestimate emissions by up to 49%.
A new study by Columbia University Mailman School of Public Health found that women living in more walkable neighborhoods have a lower risk of obesity-related cancers, particularly postmenopausal breast cancer. Neighborhood walkability is associated with increased physical activity and reduced car-dependency.
The Keck School of Medicine of USC has received a $2 million grant from the California Institute of Regenerative Medicine to further enhance its cutting-edge cGMP Laboratory. The funding will support the adoption of advanced technologies, including an electronic quality management system and optimized cell therapy manufacturing processes.
Researchers propose a new way to control moiré flatbands by adjusting the band offset of two photonic lattices, enabling the creation of novel multiresonant moiré devices. This breakthrough opens new opportunities in moiré photonics and promises to inspire future explorations into innovative moiré devices.
A new intervention for caregivers has been shown to reduce elder mistreatment of older adults with chronic illness, including dementia. The Comprehensive Older Adult and Caregiver Help (COACH) program provides personalized support to caregivers, reducing mistreatment rates from 22.5% to 0%.
A large-scale proteomics study from deCODE Genetics analyzed data from over 50,000 individuals across European, African, and Asian ancestry. The study identified over 80,000 associations between genetic variants and protein levels, as well as over 500,000 associations between diseases and other traits with protein levels.
A new study reveals that esketamine nasal spray is effective in treating treatment-resistant depression, with 27.1% of patients achieving remission after 8 weeks compared to 17.6% on quetiapine XR. Long-term data shows sustained remission rates at 21.7% for esketamine NS and 14.1% for quetiapine XR.
A new small-molecule drug candidate has been shown to increase the activity of immune cells and make tumors more vulnerable to immune attack. The molecule, ABBV-CLS-484, works by blocking proteins that normally shut down immune signals, resulting in a powerful dual response against cancer and immune cells.
A UK study found a 66% increase in freshwater invertebrates across England's rivers, with sensitive species like mayflies recovering most strongly. The improvement coincides with declines in pollutants and suggests effective water quality management.
A new CRISPR-based gene therapy platform will be developed to target genetic brain diseases like Angelman syndrome and H1-4 syndrome. The platform utilizes a novel delivery technology called STEP (Stimuli-responsive Traceless Engineering Platform), which has the capacity to revolutionize genome-editing therapy.
Researchers created a tiny 3D cell culture model that mimics the function of lymphatic vessels to explore how inflammatory substances affect the lymphatic system. They found that certain cytokines cause cells to tighten their junctions, leading to reduced fluid drainage and swelling. Inhibiting a protein called ROCK2 reversed lymphedem...
Researchers at Curtin University have created a piezoresistor the size of a human hair, revolutionizing chemical and biosensors. This breakthrough enables detection of diseases through molecular shape changes, offering new possibilities for health monitoring devices.
Current WHO TB prevention guidelines do not adequately address the needs of imprisoned populations, who are disproportionately affected by the disease. Researchers call for programs to prioritize prison inmates' access to preventive treatment.
A new study published in Nature Communications found that global sugary drink consumption increased by at least 16% since 1990, with the highest intakes observed in Latin America and Sub-Saharan Africa. The study also reveals significant regional differences and correlations between sugary drink intake and socio-economic status.
The study found an increase in eating disorder emergency department visits and hospitalizations among females aged 10-17, 18-26, 27-40, and 41-105 years during the COVID-19 pandemic. Risk factors such as isolation, social media use, and decreased access to care may have contributed to this surge.
Researchers found that relying on existing diagnostic CT scans instead of new ones for simple palliative radiation treatments reduced patient wait times from nearly five hours to under 30 minutes. This novel workflow can improve the patient experience and reduce costs, making it a promising approach for expedited care.
Research by Jamila Michener shows that organized tenants can immediately resolve direct problems and advance health equity through collective action. Tenants from diverse backgrounds across the US were interviewed for the study, highlighting the potential for power-sharing in rental housing.
Research reveals UK immigration system's reliance on anger, disgust, suspicion, and fear to cast migrants as 'threatening, polluting and irrelevant', leading to deportability and disposability. The system employs emotional governance to disenfranchise migrants, fostering racial categorization and domination.