Kumamoto University researchers discovered HMGA2's crucial role in regulating stress responses in hematopoietic stem cells. The gene enhances blood cell production recovery under stressful conditions, such as chemotherapy and infections.
A new non-hormonal hot flash treatment has been shown to significantly reduce symptom frequency and severity within weeks, while also improving sleep quality and overall well-being. The investigational drug elinzanetant was found to have a favorable safety profile with mild side effects.
Researchers have successfully infected gastrointestinal epithelial cells with Chlamydia trachomatis using lab-grown human organoids. This finding supports the theory that Chlamydia can form a reservoir in the human gut, highlighting the importance of further investigation into this potential reservoir.
Researchers at Tsinghua University Press have developed BiRefNet, a bilateral reference framework that captures tiny-pixel features and achieves highly accurate high-resolution salient object detection and concealed object detection. The framework has numerous practical applications in various fields.
Researchers have developed a bioinspired process to make marine sand more durable and resistant to erosion by applying a mild electric current. This natural cement reduces the need for expensive protection structures and provides a sustainable solution for strengthening global coastlines.
Experts predict EEG technology will enhance cognitive performance, detect learning disabilities, and provide real-time diagnosis of brain abnormalities. The technology may also enable reading dreams and memories, with personal portable devices potentially available in a generation.
Researchers at Uppsala University studied Northern krill and found extensive genetic variation critical for adaptation to different climates. The study identified hundreds of genes associated with heat and cold sensitivity, nutrient uptake, and reproduction.
A recent study published in PLOS Biology investigated the effectiveness of eLife's standard wording for evaluating scientific article importance. The research, conducted online, revealed that participants' implied rankings often diverged from the intended meaning.
A phase II clinical trial found that olaparib, a precision oncology drug, can induce durable complete remissions in recurrent prostate cancer patients with BRCA2 mutations. The study showed that 13 participants, including all 11 with BRCA2 mutations, had a decrease in PSA of at least 50% after treatment.
A pioneering study found that factories globally are not properly destroying emissions of a super-greenhouse gas emitted from the production of fluoropolymers like Teflon and refrigerants. The researchers used a novel technique to measure actual emissions, revealing a discrepancy between reported and real levels.
A groundbreaking study found that incorporating varied habitats into landscapes enhances biodiversity and ecosystem stability. Multi-habitat landscapes host a higher number of species and demonstrate improved ecological functions, including better pollination services.
Researchers directly observed Floquet states in colloidal nanoplatelets driven by visible pulses using all-optical spectroscopy. The study provided an all-optical direct observation of Floquet states in semiconductor materials and uncovered rich spectral and dynamic physics of these states.
A new technology can extract lithium from brines at an estimated cost of under 40% that of today's dominant extraction method. The approach uses redox-couple electrodialysis and is expected to be relatively inexpensive due mostly to lower capital costs.
A new study found that interval exercise is better suited for men with low blood sugar levels, while continuous exercise is more effective for women. The research suggests that gender-specific recommendations should be considered when prescribing aerobic exercise to patients with type-1 diabetes.
Researchers from Osaka University discovered that Ikaros binds to Foxp3 to inhibit the expression of target genes, including Ifng, in regulatory T cells. This interaction is crucial for maintaining immune homeostasis and preventing autoimmune disorders.
A new study by Neil Sehgal and Ashwini Sehgal found that US Congress members whose ancestors enslaved 16 or more people had a net worth five times higher than those without slaveholding history. The researchers noted limitations, including lack of information on pre-1776 slavery and potential biases in the dataset.
A recent study from the University of Delaware has analyzed a high-quality carbonate dataset to investigate anthropogenic carbon dioxide in coastal waters. The researchers found that surface water shows high levels of anthropogenic carbon dioxide, while middle and deep layers have lower concentrations.
University of Queensland researchers identified two enzymes that regulate adenine methylation in mitochondrial DNA, which controls disease-causing mutations. Enhancing levels of this modification may slow disease progression and provide a new perspective on genetic and epigenetic factors in health and disease.
A recent study published in Developmental Medicine & Child Neurology reveals that children born extremely preterm are at a higher risk of autism diagnosis. The screening test was effective in identifying autism in preterm children, with only a small percentage who screened positive later receiving no diagnosis.
A recent study published with the Arkansas Agricultural Experiment Station found that ChatGPT can be a useful tool in teaching agriculture students to program microcontrollers. The study, which aimed to determine the confidence of undergraduate agricultural students in using ChatGPT to write Arduino code for moderately difficult progra...
The study found that robotic postural stand training with epidural stimulation improved trunk control during standing tasks, but had no significant impact on sitting outcomes for high-level motor-complete individuals with SCI. This suggests that rehabilitation strategies should be tailored to target specific postures.
Researchers have successfully produced biodegradable plastics with ring-like structures, which could be used for biomedical applications such as drug delivery. The bacteria-based production method has the potential to replace petroleum-based plastics, offering a sustainable alternative.
Researchers at Shenzhen Institute of Advanced Technology developed a novel approach to create degradable living plastics by programming spores to secrete enzymes that break down plastic. The 'living plastics' degrade efficiently within 6-7 days, outperforming regular plastics even with surface damage.
The MedPearl platform improved primary care clinician productivity, decreasing time waste on administrative tasks and enhancing the quality of referrals to specialists. Clinician users reported a 72% improvement in clinical management and workups, with a high user retention rate after system-wide integration.
A recent study published in the Scandinavian Journal of Medicine & Science in Sports found that reduced body flexibility is associated with poor survival in middle-aged men and women. After analyzing data from 3,139 participants, researchers discovered an inverse relationship between Flexindex scores and mortality risk.
Researchers found that floating objects can reach Antarctic waters from more sources than previously thought, threatening the continent's unique ecosystems. Non-native marine species can colonize Antarctica by catching a ride on kelp, driftwood, and plastic debris.
Michigan State University researchers have found a new way to prevent antibiotic resistance by unleashing 'DNA scavengers' in wastewater treatment plants. The enzyme, developed by Syed Hashsham and James Tiedje, breaks up strands of antibiotic-resistant DNA before bacteria can pick them up and take on their properties.
The WPI team will develop an inexpensive test kit that can quickly identify vulnerable species and track illegal wildlife trade on social networks. The project aims to disrupt the multi-billion-dollar industry by providing law enforcement with real-time results and long-term trends.
Researchers discovered a timer integrated into CRISPR gene scissors that enables them to switch themselves off after a viral attack. The CalpL protein triggers a signaling cascade to help the cell survive the viral attack, but breaking down cyclic oligoadenylates regulates the immune response and returns the cell to normal conditions.
A team of scientists developed a flexible mode-switching system utilizing an optical neural network chip to switch between different Orbital Angular Momentum (OAM) modes in a multimode fibre. The system achieved low-crosstalk mode switching, enabling efficient and flexible optical networks capable of meeting growing demands.
A study found that neuroticism can negatively affect general and inhibitory self-control, while a positive correlation was seen for extraversion and conscientiousness. Understanding the nuanced interplay between personality traits and self-control is essential for developing effective interventions.
Researchers have successfully assembled the first chromosome-level genome of Chinese cherry, providing insights into fruit firmness. The study identified key genes involved in pectin biosynthesis and modification, promising targets for future genetic improvements.
Octapharma USA, a US Army Medical Materiel Development Activity commercial partner, has received FDA emergency use authorization for octaplasLG Powder, a potentially lifesaving treatment option for blood replacement therapies in certain operational circumstances. The EUA authorizes military medical commands to procuring and administeri...
A new study reveals that fasting helps regenerate and heal intestinal injuries, but also increases the risk of developing early-stage intestinal tumors in mice. The researchers identified a pathway enabling this enhanced regeneration, which is activated during refeeding after fasting.
The distribution of outermost shell electrons was experimentally observed in organic molecules, revealing a fragmented electron cloud distribution. This demonstrates the quantum mechanical wave nature of electrons and validates a theoretical model proposed by quantum chemistry.
The University of Kansas has received a $26 million grant from the National Science Foundation to create a new Engineering Research Center focused on developing sustainable refrigerant technologies. The EARTH center will address the challenge of replacing hydrofluorocarbons with safer, more environmentally-friendly alternatives.
Scientists at IOCB Prague have developed a new compound that suppresses appetite and protects the brain against Alzheimer's disease. The modified molecule, derived from the neuropeptide CART, is effective in reducing pathology associated with Alzheimer's.
A new measure identifies school-age children and adolescents with the highest chances of having Long COVID based on long-term symptoms. Researchers found that prolonged symptoms affect almost every organ system, with distinct patterns in children and teens, highlighting the need for further study and monitoring.
A large study of female participants found no association between migraine and the development of Parkinson's disease, contrary to previous research. The study followed over 39,000 women for an average of 22 years and adjusted for various risk factors.
A randomized clinical trial found camu-camu extract reduced liver lipids by 7.43%, while a placebo increased them by 8.42%. The effect is attributed to polyphenols and their relationship with intestinal microbiota.
Researchers from UC Irvine have discovered the neurons responsible for item memory, a crucial component of cognitive function. The study sheds light on how the brain stores and retrieves memories, particularly in relation to rewards or punishments.
A large-scale study investigated the relationship between childhood obesity and immune-mediated skin diseases (IMSDs), such as atopic dermatitis and psoriasis. The study found that obese children were more likely to develop these conditions, with changes in body weight affecting their risk of developing these diseases.
The new ERC EARTH research center will focus on developing sustainable refrigerant technologies and practices to improve quality of life and combat climate change. Lehigh University's team, led by David Vicic, will work on reclamation and repurposing of high-GWP legacy refrigerants.
A pilot study found that partially substituting soil with recycled glass fragments speeds up plant development and reduces unwanted fungal growth. The researchers grew cilantro, bell pepper, and jalapeño plants in pots containing different ratios of glass to soil.
Researchers at TU Graz have observed where lithium ions are stored and released from battery material during charging and discharging cycles. They found that even fully charged batteries retain lithium ions in the crystal lattice of the cathode, leading to a capacity loss. This knowledge can help increase battery capacity further.
Researchers at McGill University found that zebra finches deprived of early social experiences can still form strong bonds with a partner later in life. Female finches developed a preference for their partner's song only when they lived together, suggesting quality time is essential for forming strong bonds.
A novel PET/CT technique has been developed to detect neuroblastoma in children with high sensitivity and short scan time, eliminating the need for sedation or anesthesia. The new technique uses a novel tracer and next-generation scanner, resulting in improved diagnostic accuracy and reduced radiation exposure.
Researchers discovered that pythons' hearts grow 25% in the first 24 hours after eating, with specialized genes kicking into action to boost metabolism fortyfold. This process could lead to novel treatments for cardiac fibrosis and other modern-day ailments.
A recent study published in JAMA Psychiatry found that children with persistently raised inflammation are at a higher risk of experiencing serious mental health disorders, including psychosis and depression, in early adulthood. The research also discovered that those who experienced inflammation at a young age were more likely to devel...
The Adaptive-k method adapts the number of samples selected for updating from mini-batches to effectively separate noisy samples. It outperforms other algorithms on various image and text datasets, demonstrating its potential to revolutionize deep learning model training in label noisy datasets.
A preclinical study found that enhancing PGK1 activity can restore neuronal energy supply in low-fuel conditions, preventing axon dysfunction and degeneration. The researchers also discovered the unexpected role of DJ-1 as an energy-supplying partner of PGK1.
Pediatric functional gastrointestinal disorders are complex conditions with a significant impact on children's health and quality of life. The ROME IV criteria facilitate earlier and more accurate diagnosis, while a multidisciplinary approach to management offers hope for improved outcomes.
Researchers found that honey bees consistently had higher levels of viruses than bumble bees, suggesting they may be reinfecting native bee communities each spring. Good honey bee colony management is crucial for healthy pollinator communities.
A recent study by Professors Eunseok Ro and Josephine Mijin Lee from Pusan National University reveals that self-deprecation serves different interactional goals, such as defense, reprimand, and accusation, depending on the context. The researchers analyzed three excerpts from Korean TV shows, Infinite Challenge and I Am Solo, demonstr...
Researchers have developed a chalk-based coating that cools the air underneath treated fabric by up to 15 degrees Fahrenheit. The innovative coating uses natural materials and can be applied to nearly any commercially available fabric.
LMU physicists have developed a new theoretical model that explains the formation of active foams from protein filaments and molecular motors. The research reveals that increasing microtubule density leads to the emergence of these complex patterns, which have an ordered structure and can rearrange themselves repeatedly.
A recent study found that Chinese patients with ovarian cancer often carry a specific variant of the RAD51D gene, which can promote tumor growth. The variant also makes these patients more sensitive to PARP inhibitors, leading to a favorable prognosis and potential new treatment methods.
Researchers analyzed public perceptions of historic urban landscapes in Shaoxing, China, revealing that different characteristics affect sentiments differently on weekdays and weekends. Urban designers should develop targeted plans to balance preservation with development, ensuring a sustainable environment and people's well-being.
By 2070, human-wildlife overlap is projected to increase in about 57% of global lands, primarily due to expanding human populations. This shift will lead to more conflicts between humans and animals, highlighting the need for conservation efforts.
A new study led by Dartmouth researchers questions the rapid polar ice collapse model used in the IPCC's sixth assessment report. The team found that the expected rate of retreat is significantly lower than predicted, making the worst-case scenario less likely, but still dire due to ongoing ice loss from Greenland and Antarctica.