Researchers have discovered compounds that convert the Bcl-2 protein, which protects cancer cells, into a tumor killer. The findings open the door to promising therapies for breast cancer and other malignancies that rely on Bcl-2 to evade treatment and develop drug resistance.
SourceOregon State University·JournalACS Pharmacology & Translational Science·TypeExperimental study·DateJun 29, 2024
Ephemeral streams are a substantial pathway for water transfer with significant implications for water quality, transporting pollutants and sediments to rivers and lakes. A recent study found that these streams account for over half of annual discharge from U.S. drainage networks, highlighting the need for enhanced regulation.
A new mouse study suggests that elenolic acid can lower blood sugar levels and promote weight loss in obese mice with diabetes. The compound was found to induce the release of metabolic hormones GLP-1 and PYY, leading to improved glucose regulation and insulin sensitivity.
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A recent study published by American Society for Nutrition found that paternal fish oil supplementation can lead to lower body weight and improved metabolic health in offspring. Researchers gave male mice a high-fat diet with or without added fish oil, then mated them with female mice on a healthy low-fat diet.
A recent study found that nearly half of those who lost Medicaid coverage during the Medicaid unwinding process were left uninsured by late 2023. The researchers also discovered that individuals who had been disenrolled reported significantly worse access to healthcare, including more cost-related delays in care and less affordability.
SourceHarvard T.H. Chan School of Public Health·JournalJAMA Health Forum·TypeSurvey·DateJun 29, 2024
Research findings suggest that higher intakes of calcium and zinc before conception can lower the risk of hypertensive disorders during pregnancy. Participants with higher pre-conception intakes of these essential minerals were 24% less likely to experience hypertensive disorders compared to those with lower intakes.
A survey study found that 6 months into Medicaid unwinding, 1 in 8 beneficiaries reported exiting the program, with wide state variation. Many who lost coverage experienced gaps in care, and adults exiting Medicaid faced more difficulties accessing healthcare services than those remaining enrolled.
SourceJAMA Network·JournalJAMA Health Forum·DateJun 29, 2024
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