Researchers have developed a new sodium-ion battery cathode material that combines large grains, suppressed phase transitions, and improved Na+ transport kinetics. The material shows high energy density and good cycle performance, making it suitable for practical applications.
A nationwide Swedish study of 221,000 individuals with ADHD found that medication use was associated with lower rates of psychiatric and non-psychiatric morbidity. The results also showed a significant reduction in hospitalizations for both types of morbidity and suicidal behavior.
Researchers found that ageing reduces the ability of regulatory T cells to enhance myelin regeneration, which can have profound consequences for neurological functions. The study suggests that the loss of function may be reversible, and two new molecules, ITGA2 and MCAM, have been identified as potential therapeutic targets.
Medicare expenditures were higher for Black and Hispanic individuals compared to whites, with average total costs ranging from $136,326 to $165,730. The analysis attributed these differences to greater use of high-cost care during the last year of life.
Adding ribociclib to hormone therapy improves invasive disease-free survival by 90.4% at three years, distant disease-free survival by 90.8%, and recurrence-free survival by 91.7%. The study found a 25% relative reduction in recurrence rate for patients with stage 2 or 3 HR-positive, HER2-negative early breast cancer.
A new study from the University of Portsmouth found that people with musculoskeletal pain complaints tend to retire earlier compared to pain-free participants. Participants suffering from musculoskeletal pain were also 1.25 times more likely to cease work sooner, whether or not they described themselves as retired.
Researchers from Peking University developed a miniaturized implantable sensor that can wirelessly monitor health parameters without transcutaneous wires or bulky equipment. The system showed promising capabilities in measuring critical parameters such as cerebrospinal fluid viscosity and glucose levels in rat models.
Researchers developed generative AI tools to predict protein structures and understand enzyme function. The study reveals the link between evolutionary patterns and catalytic activity, enabling the successful engineering of proteins like luciferase.
Researchers found a link between low fiber diets, mucin-degrading bacteria, and increased inflammation in mice with IBD genetics. A high-fiber diet prevented inflammation and even reversed symptoms in some cases.
A 25% decline in doctors' real terms salary since 2008 has significantly reduced their purchasing power, with junior doctors facing particularly challenging affordability issues. The study reveals a substantial rise in the cost of living and house prices, making home ownership and financial stability unaffordable for many doctors.
Researchers developed FloorLocator, a game-changer in indoor navigation technology combining Spiking Neural Networks with Graph Neural Networks for remarkable accuracy and scalability. It surpasses traditional methods by leveraging deep learning without the drawbacks of extensive training data and high computational costs.
A new study has found that people are less likely to acknowledge war crimes on social media, citing fear of being stereotyped and judged. The research suggests that social media can be a barrier to post-conflict reconciliation, particularly when it comes to discussing the legacy of war.
Researchers at Lehigh University found that low- to mid-level flooding events are the most vulnerable to cyber attacks, which can overwhelm the system and cause a flood downstream. The study developed a mathematical framework to identify vulnerabilities in stormwater systems, allowing municipalities to assess their risks.
A new study from Ohio State University Wexner Medical Center found that treating anxiety and depression significantly improves heart disease outcomes, with a 75% reduction in hospitalizations or emergency room visits. The study suggests a collaborative care model is essential for managing cardiovascular and mental health.
A new study by Lund University finds that people's responses to the Cantril Ladder question often prioritize power and wealth over broader definitions of happiness and well-being. Tweaking the question to emphasize 'most harmonious life' reduces thoughts of wealth, but not entirely eliminates them.
A new commentary from Boston University School of Public Health emphasizes the need to address digital redlining, which disproportionately affects people of color, low-income communities, and rural populations. The authors propose standardizing social determinants of health screenings to include questions about broadband access.
A team of researchers decoded the origins and spread of the bottle gourd, a staple in ancient civilizations for over 10,000 years. The study mapped the genetic blueprint of 197 varieties, revealing its domestication in Southern Africa around 12,000 years ago.
Oxford researchers call for a more considered approach to AI development for children, highlighting four main challenges in applying existing ethical principles. The study recommends ensuring fair digital access, transparency, and safety, while involving children in system development.
A group of high school students from the Galaxy Explorer program made contributions to exoplanet research using backpack-sized digital smart telescopes. They observed and confirmed a warm and dense sub-Saturn planet, TIC 139270665 b, orbiting a metal-rich star.
Scientists identified key factors in developing long-lasting immunity against dengue virus through analyzing immune responses to natural infection and vaccines. The study revealed molecular markers that could be used in novel vaccine development.
A new AI tool can predict which breast cancer patients are at risk of chronic arm swelling after surgery and radiotherapy. The tool, developed by international researchers, uses machine learning algorithms to analyze patient data and provides easily understandable explanations for doctors and patients.
A new material has been developed with adaptive durability, meaning it becomes stronger and more conductive when subjected to impact or stretching. The material's conductivity is also improved by adding a small amount of PEDOT:PSS, making it suitable for wearable devices and personalized medical sensors.
Researchers at Georgia Tech have developed a universal approach to controlling robotic exoskeletons that requires no training, calibration, or adjustments. The system uses deep learning to autonomously adjust assistance levels for walking, standing, and climbing stairs, reducing user effort and metabolic expenditure.
A Rutgers study reveals that nonprofits with a stronger utilitarian identity tend to acknowledge the importance of listening but fail to implement changes. In contrast, those with a normative identity prioritize stakeholder inputs and interests. The study highlights the need for mutually reinforcing identities in NPOs.
Researchers at CRAG have made groundbreaking discoveries on seed germination, identifying key regulatory features and non-coding RNAs that drive the process. The study reveals that transcription restarts much earlier than previously thought, opening up new avenues for investigation into the role of the non-coding genome.
A study published in Nature Metabolism reveals that the diabetes drug metformin and solid foods increase a hunger-reducing factor called Lac-Phe, while sugary drinks have minimal effect. This discovery could lead to new anti-obesity treatments and help explain why liquid calories drive obesity.
A new analysis published in Andrology found a higher genetic susceptibility to leisure computer usage was associated with a greater risk of erectile dysfunction in men. Each 1.2 hour increase in leisure computer usage predicted a 3.57-fold greater odds of erectile dysfunction.
A skin biopsy test detects abnormal alpha-synuclein protein in patients with Parkinson's disease, dementia with Lewy bodies, and related disorders. The test showed high accuracy rates, validating its reliability for early diagnosis and clinical drug development.
A new study reveals that US working-age adults are dying at higher rates than their peers in high-income countries, driven by highly preventable causes of death. Midlife mortality among younger US females has worsened significantly over the past three decades, with the UK and other high-income countries experiencing similar trends.
Researchers monitored astronauts' muscle health using a handheld device, revealing crucial lower leg muscles are at risk of weakening. The technology could also help monitor muscle health in neuro-musculoskeletal conditions like Parkinson's Disease.
A study of 3,000 middle-aged and older women found that those who perceived gender discrimination reported declines in wellbeing over time, including more depressive symptoms, loneliness, and lower quality of life. Perceived sexism was linked to depression, loneliness, and poor life satisfaction six years later.
A researcher at the University of Arizona is using a $750,000 NIH grant to develop methodology for reducing asthma risks among nurses. Preliminary survey data suggest that nurses prioritize lower asthma risks over increased infection risks.
A UNIGE team has identified the mechanism of action of PARP inhibitors, used to treat breast and ovarian cancer. By blocking one activity while preserving another, these inhibitors can maintain toxic effects on cancer cells while sparing healthy cells.
Researchers at Fred Hutchinson Cancer Center found that a specific subtype of Fusobacterium nucleatum is responsible for tumor growth in up to 50% of human colorectal cancers. The study identifies the exact bacterial lineage associated with colorectal cancer, offering opportunities for developing microbial cellular therapies.
Researchers unveiled a theoretical model that shows specific structural details on surfaces can influence water's freezing point. The model identifies angles between microscopic bumps on a surface that make it easier for water molecules to crystallize at relatively warmer temperatures.
Researchers have developed a new method to verify the accuracy of complex quantum systems using classical computers. The method allows for estimating error rates and is mathematically sound, providing a benchmark for analyzing errors in quantum computing systems. This breakthrough enables improvements to be measured effectively.
A combined PET-MRI scan improved treatment outcomes for 57 out of 205 patients with early-stage breast cancer. The scan helped doctors spot signs of tumour spread, enabling alternative treatments such as chemotherapy or different surgical approaches.
A new study found that while NHSC clinicians increased from 2003-2008 to 2009-2019, concordance with the target population remained low. After expansion, concordance was achieved for non-Hispanic White and Black individuals, but Hispanic clinicians were still underrepresented.
Researchers found that early antibiotic treatment accelerated recovery in COVID-19 patients. The study used a combination of antibiotics, including amoxicillin and rifaximin, within the first three days of infection. This treatment significantly reduced the risk of long-term COVID symptoms.
NeXT Personal assay detects up to ~1,800 somatic variants specific to the patient's tumor with a detection threshold of 1.67 PPM and 99.9% specificity. The assay showed linearity over a range of 0.8 to 300,000 PPM.
Scientists from UC3M and Johns Hopkins University have developed a computational model that simulates the invasion process of cancer cells based on the characteristics of surrounding tissue and cell junctions. The model allows for predicting tumor evolution in patients by analyzing mechanical properties of the microenvironment.
The study provides reference electrocardiographic data for elite female basketball athletes, highlighting common international criteria-defined training-related findings. Abnormal ECG findings were rare in this athlete group, suggesting a low risk of cardiovascular issues.
The DTEP model accurately predicts delayed treatment effects (DTE) in immuno-oncology trials, allowing for optimized trial designs. By tailoring trial lengths, the model enhances statistical power and accelerates immunotherapy development.
Researchers propose changing election certification to use independent, nonpartisan commissions to minimize politics' influence. Broad public support exists for this reform, with over 70% of voters supporting its use.
Researchers tested publicly accessible AI assistants on two health disinformation topics, finding that many consistently generated disinformation despite having built-in safeguards. Experts call for enhanced regulation, transparency, and routine auditing to prevent LLMs from contributing to the mass generation of health disinformation.
Researchers used ChatGPT to design a university field course, finding it an effective tool for planning educational trips. The AI model was also adaptable for other industries, such as environmental impact studies and business trips.
A new study from the University of Sheffield found that around 32% of the global population is at risk of serious health issues due to high levels of arsenic in drinking water. The majority of these countries are in Asia, where rice is a staple food and exposure can be exacerbated by cooking with contaminated water.
Research highlights advances in developmental executive functions study from Latin American regions, finding both universality and cultural specificity in EFs development. This contextualized approach fosters effective pathways for supporting children's cognitive and emotional development.
A recent study from University of Nebraska-Lincoln scholar Ciera Kirkpatrick explores the impact of idealized social media portrayals of motherhood on new mothers. The research found that exposure to such idealizations increases anxiety and envy among moms, particularly those with a higher social comparison orientation.
Researchers analyzed large craters on Europa to determine the ice shell's thickness, finding it to be at least 20 kilometers thick. This conclusion is based on the study of impact cratering and the combination of physical characteristics that could have created such a surface structure.
A two-question survey identifies patients at risk of poor pain outcomes, who are then steered to holistic services with significant reductions in morphine dose. Holistic interventions, including pain management and behavioral health programs, lead to better outcomes than traditional chronic pain management approaches.
The new campus brings together expertise on atmospheric and biodiversity research to study interactions between the atmosphere and biosphere, particularly in the context of rapid climate change. Researchers will investigate effects of aerosol particles from vegetation on air quality, Earth's radiation balance and vegetation patterns.
A recent study analyzed 306,800 US suicide deaths between 2003 and 2020 and found that physical health concerns were a significant risk factor for suicide. The largest subgroup of individuals who died by suicide had no documented mental health issues or antidepressant use.
A new species of freshwater dolphin, Pebanista yacuruna, was found in the Peruvian Amazon region and is dated to be 16 million years old. The discovery sheds light on the evolutionary history of freshwater dolphins, revealing a deep connection with South Asian river dolphins.
A Mayo Clinic study found that microglia shield neurons from the aftereffects of anesthesia, enhancing and boosting neuronal activity to awaken the brain. This discovery could lead to new treatments for post-anesthesia delirium and hyperactivity.
A recent NIH-supported study found that SARS-CoV-2 can damage the heart by triggering inflammation in cardiac macrophages. The research suggests that suppressing this inflammatory response may help minimize cardiovascular complications.
Researchers at Boston University School of Medicine created a new scale for hyperpigmentation, the Post-inflammatory Dyspigmentation Area and Severity Index (PIDASI), which performs well in patients with varying skin tones.
A survey of UK, Austria, and Denmark pet owners found that 6 in 10 believe their pets should have access to the same healthcare treatment options as humans. Those with strongest emotional attachments to their pets were more likely to desire advanced care options.
Researchers at Yale University and NOVA University Lisbon discovered that a single family of proteins in soil bacteria acts as plugs to power nanowires, creating a natural electrical grid. This finding has implications for developing new energy sources and biomaterials, as well as mitigating methane emissions.
The study found that the improvement in air quality has led to a significant reduction in fine particles and nitrogen oxides, resulting in large health gains. Despite improvements, many residents are still exposed to high levels of air pollution, highlighting the need for continued efforts to reduce emissions.