A study published in Science of The Total Environment found that Legionella pneumophila bacteria can withstand thermal stress and remain viable but non-culturable. This highlights the limitations of current detection methods and emphasizes the need to consider this subpopulation in assessments.
Astronomers propose a new model to explain the origin of phosphorus, with ONe novae as a major source. The theory predicts a large amount of phosphorus will be released in these events, which would have been readily available when the Solar System formed.
Researchers from the University of Hong Kong develop a novel fluidic system called VasFluidics, which can modulate fluid compositions via spatially-different reactions. This discovery has promising applications in developing artificial blood vessels and biomimetic platforms for various biomedical applications.
Researchers have developed a prototype 'smart' contact lens that measures eye pressure accurately, regardless of temperature. The dual-circuit design removes temperature-related errors, enabling early detection and monitoring of glaucoma.
A new study links interpersonal discrimination to changes at the molecular level, revealing a potential root cause of disparities in aging-related illness and death. Discrimination is consistently associated with accelerated biological aging, with everyday and major forms being linked to faster aging.
Researchers analyzed genome of Oikopleura dioica, finding it has wildly different languages despite identical physical characteristics. The 'scrambling' phenomenon suggests genes are regulated differently, challenging assumptions about species identity.
Dr. Jedd Wolchok joins the Vilcek Foundation board with a wealth of experience in immunotherapy and oncology, having previously served as a juror for the foundation's Creative Promise prizes. His appointment comes after establishing himself as a leader in his field through groundbreaking research and clinical trials.
A study found that healthcare professionals attending certain endoscopic gastrointestinal procedures can be exposed to dangerous toxin levels, similar to smoking a cigarette. The researchers suggest possible solutions such as using insufflators or masks to reduce smoke exposure during procedures.
This study found that perceiving high glossiness in images induces greater pupillary constriction than perceived low glossiness, even when physical luminance is adjusted. The results suggest that the visual system responds to specular highlights in glossy images, leading to pupil constriction.
Researchers used field observation and atmospheric chemistry models to explore the source of ammonium in PM2.5 during haze pollution in Beijing's winter. Combustion-related ammonia sources, including fossil fuels, biomass burning, contribute significantly to ammonium formation.
A Rutgers Health study examines the importance of social support networks for older adults living with HIV, finding that strong connections can reduce stress and anxiety. The research also emphasizes the need for increased funding and programs to foster positive social interactions and improve overall quality of life.
A study by Brigham and Women's Hospital found that patients with limited English proficiency are more likely to rate video health care visits as worse than in-person appointments, despite having access to telehealth services. The study highlights the need for designing telehealth platforms that better serve marginalized populations.
Residents in the UK have complex views on the introduced ring-necked parakeet, with acceptance of urban presence but resistance in rural areas. Concerns include competition with native birds and unknown impacts on local ecosystems. The study suggests a possible generational divide in perceptions.
In Brazil, deaths from diabetes and hypertension have increased significantly since 2020, even after excluding those linked to COVID-19. This persistent trend highlights the need for continued efforts to address these major public health concerns.
Researchers have identified a population of mesothelial-like cells in omental adipose tissue that limit fat cell formation, offering new insights into the mechanisms underlying obesity. These cells secrete Insulin-like Growth Factor Binding Protein 2, which inhibits adipogenesis and regulates metabolic behavior.
A new study found that sea surface temperature anomalies in the Indian Ocean can predict the magnitude of global dengue epidemics. The research, published in Science, suggests that this climate indicator could enhance forecasting and planning for outbreak responses.
Researchers have successfully grown functional human liver cells in a different species, offering a potential solution to the shortage of donor organs for liver transplants. The breakthrough uses interspecies blastocyst complementation to produce transplantable human liver cells, which can effectively mitigate chronic liver fibrosis.
Between 1999 and 2020, colorectal cancer incidence grew by 500% among children ages 10-14, 333% among teens aged 15-19, and 185% among young adults ages 20-24. Researchers highlight the need for tailored approaches to screening and awareness of signs and symptoms.
Researchers have identified a promising new vaccine adjuvant called C100, derived from chitin, which stimulates key sensing and signalling molecules to regulate anti-tumour immune responses. The discovery offers hope for developing effective adjuvants for in situ vaccines in cancer immunotherapy.
A recent study by University of Nebraska-Lincoln professor Cory Armstrong found that roughly 50% of those surveyed in the mid-south region couldn't accurately define a tornado warning. Meanwhile, 35% correctly identified a warning as a tornado being sighted or indicated on weather radar.
Researchers found that weaker ocean currents during the Younger Dryas period led to a decline in nutrient availability, resulting in decreased biological productivity in the North Atlantic. This study supports predictions about the impact of climate change on ocean circulation and life.
A study by IBS researchers has identified the anterior cingulate cortex (ACC) as a key region responsible for sensory hypersensitivity associated with autism spectrum disorders. The team discovered that ACC hyperactivity and brain-wide hyperconnectivity contribute to sensory abnormalities in Grin2b-mutant mice.
Researchers have discovered a radically different molecular switch that determines sex in African butterflies, relying on recognition of sequence differences within the Masculinizer gene. This alternative mechanism leads to hypervariability of the Masculinizer gene and drives the production of more females than expected.
Scientists have discovered that aging clocks measure stochastic changes in cells, rather than damage accumulation. This finding suggests that aging can be predicted using the variation in cellular processes.
A new study from Washington State University found that just a few days on a night shift schedule can disrupt protein rhythms related to blood glucose regulation and energy metabolism. This dysregulation may lead to chronic metabolic conditions such as diabetes and obesity.
A team of Harvard researchers, led by Jeff Lichtman, has created the largest synaptic-resolution, 3D reconstruction of a piece of human brain to date. The dataset contains 1,400 terabytes of data on neural connections in a tiny piece of human temporal cortex.
A UC San Diego study found that people injecting drugs in San Diego and Tijuana often lacked access to drinking water, toilets, handwashing facilities, and showers. The study highlights the need for improved access to safe water, sanitation, and hygiene services in both cities to reduce health disparities.
Researchers introduce novel deep learning methods for channel extrapolation and beamforming in terahertz communication systems. These methods offer significant improvements in efficiency and robustness, addressing challenges in imperfect channel state information conditions.
A team of chemists discovered that cyclopropanation reactions can take the scenic route, producing intricate molecular structures and unexpected side-reactions. Advanced techniques revealed a complex network of forking chemical pathways, showcasing the need for open-minded research and consideration of all possible side-reactions.
A new analysis of 100 largest MPAs reveals slow implementation and inadequate regulations, raising concerns about conservation efforts. Effective design and management are crucial to achieving the goal of protecting at least 30% of the ocean by 2030.
An international team of researchers has discovered that the quantum particles responsible for material vibrations can be classified through topology. The study found that at least half of materials exhibit non-atomic cumulative phononic band sets, leading to potential applications in frequency filtering and mechanical energy attenuation.
A team of scientists at NIMS and Nagoya University has developed a novel method to create transverse thermoelectric conversion materials from common soft magnetic alloys. By applying a short period of heat treatment, they significantly improve the performance of anomalous Nernst effect, leading to enhanced energy efficiency and thermal...
A new endoscopic procedure has been developed to reduce production of ghrelin, a key hunger hormone, by ablating the stomach lining. This process resulted in a 7.7% body weight loss and a 40% reduction in fasting ghrelin levels in a six-month trial involving 10 female patients with obesity.
Researchers have developed a novel strategy to boost the ability of human natural killer cells to combat hematologic malignancies by blocking CD300A, a known immune checkpoint. This approach led to a significant improvement in survival rates of mice with xenografted human blood cancer cells.
The Penn State research project, funded with a $1.33 million DOE grant, focuses on replacing coal-based materials with biomass in steel manufacturing to reduce greenhouse gas emissions. Additionally, the researchers plan to introduce a microcredential program to provide industry-specific training for underrepresented groups.
Researchers at PolyU developed a new class of 2D all-organic perovskites with high dielectric constants, surpassing those of silicon dioxide and hexagonal boron nitride. These materials show promise for use in 2D electronics, enabling superior control over current flow and potential applications in capacitors and transistors.
Researchers have developed cold sintering to recycle materials repeatedly without a decrease in quality. This process combines powder-based materials into dense forms at low temperatures and allows for recycling multiple times.
A new approach developed by Duke Human Vaccine Institute guides the immune system through specific steps to make broadly neutralizing antibodies against HIV. The mutation-guided vaccine strategy has shown promise in triggering the immune system to produce desired antibodies, potentially applicable to vaccines targeting other diseases.
A new framework aims to facilitate better communication between authors, reviewers, and readers of observational studies. The proposed guidelines promote the adoption of intervention effects in medical journals, enabling more accurate causal inference.
Environmental and hydrologic models predict a larger-than-expected decline in suitable malaria transmission areas in Africa, starting after 2025. The new study incorporates hydrologic metrics that account for river inflow and densely populated areas near large-scale river networks.
A new study by the University of Plymouth found that saturated soils in upland regions could negatively impact the survival rates of young oak saplings and acorns. The research highlights the importance of considering soil conditions when creating temperate rainforests to combat climate change.
Neighborhoods of high need offer opportunities to improve health through social care integration, which requires infrastructure development and financial investment. Building and maintaining this infrastructure will cost $1-3 million per year for 5-10 years, according to a case study by Eskenazi Health.
Researchers developed a Pix-2-Pix GAN model to correct PSMA PET/CT images, improving image quality and quantitative markers. The AI-generated images show high correlation with original images and potential for reducing CT scans without compromising image quality.
Researchers identified distinct differences between oral microbiomes of healthy patients and those with gastric cancer or pre-cancerous conditions. The findings suggest that oral bacteria could serve as biomarkers for gastric cancer risk, potentially leading to practice-changing tests and guidelines.
A six-center case-control study investigated the association between miR-146a rs2910164 C>G polymorphism and Wilms tumor susceptibility in Chinese children. No significant relationship was found, suggesting no association with increased risk.
A new study found that communities with higher-than-average illegal market opportunities are more likely to be targeted by organised crime groups. Organised crime offenders tend to move into areas with similar socio-demographic profiles and target urban communities with higher levels of criminal activity.
Researchers will use high-resolution scans and data analysis to investigate the influence of genes and environment on tooth morphology in two primate species. The study aims to advance bioanthropological practice and provide a comprehensive understanding of dental genetic architecture.
Researchers have achieved fast photoionisation detection of single Er3+ ions in silicon, enabling rapid readout of optical centers with time resolution better than 100 nanoseconds. This breakthrough has significant implications for scalable quantum systems and high-precision sensing applications.
A recent study published in Blood Neoplasia found that older adults with acute myeloid leukemia (AML) can derive benefit from the VEN-HMA regimen, which is the standard of care for older AML patients. The treatment was shown to durably prolong survival in approximately 20-25% of treated patients.
Researchers found that neural networks struggle to precisely resolve both conjugate variables simultaneously, hinting at an intrinsic vulnerability. This insight is crucial for developing new protective measures against sophisticated threats.
Research by the University of East Anglia reveals that net zero plans show limited ambition in dealing with residual emissions, which are expected to come from hard-to-abate sectors such as aviation and agriculture. The study analyzed national climate strategies for 71 countries, finding that only 26 quantify residual emissions, with m...
A new study analyzed 31 previous studies on global health programs to find common themes in public health success. The researchers identified eight key drivers, including efficient data systems, effective leadership, and women's empowerment, that contributed to exceptional outcomes.
Researchers found a significant association between neighborhood deprivation and DNA methylation in brain tissue, which may be linked to immune response. The study identified one CpG site (cg26514961, PLXNC1 gene) significantly associated with neighborhood deprivation after controlling for covariates.
A new assessment tool developed by researchers at Northwestern University predicts suicidal thoughts and behaviors with an average accuracy of 92%. The tool uses a simple picture-ranking task along with contextual variables to identify individuals at risk of self-harm.
A groundbreaking study published in Cancer Biology & Medicine found female recipients experience significantly better post-transplant outcomes than male counterparts. The research suggests that organ allocation should account for recipient sex, potentially leading to improved care and fairness in the process.
Generative artificial intelligence and social media can erode capacities for creative thinking and problem-solving, foster feelings of hopelessness, and reduce attention on the climate crisis. Researchers are calling for a cautious review of generative AI to mitigate its indirect impacts on climate change.
Researchers at the University of Arizona and Sandia National Laboratories have developed a new class of synthetic materials that enable giant nonlinear interactions between phonons. This breakthrough could lead to smaller, more efficient wireless devices, such as smartphones or other data transmitters.
The project aims to extract and concentrate rare earth elements from domestic coal-based acid mine drainage, producing high-purity materials for magnet and super alloy applications. The goal is to establish a 100% domestic supply chain, reducing U.S. reliance on foreign suppliers.
A new COVID-related syndrome, MDA5-autoimmunity and Interstitial Pneumonitis Contemporaneous with COVID-19 (MIP-C), has been identified in patients with severe lung scarring and autoimmune diseases. The syndrome was discovered through a retrospective observational study by UC San Diego researchers and UK colleagues.
Researchers have found a novel hexa-coordinated Ti site on the surface of mesopores that enables efficient oxidative desulfurization. The team discovered that two Ti-OH groups interact with oxidant via hydrogen bonds, leading to a low-energy reaction pathway.