A new study reveals DNAN, a chemical compound replacing TNT in explosives, harms plants by accumulating throughout the plant and lingering for longer. This poses a risk of animals consuming infected plants, introducing toxin into the food chain.
The new RTG EpiSignal focuses on the interaction between chromatin modifications and cell signaling networks in regulating cellular processes. The researchers aim to uncover molecular mechanisms that determine their interplay, shedding light on fundamental mechanisms underlying cellular decision-making.
Researchers analyzed hundreds of malaria parasite genomes to identify genetic variants associated with drug resistance. The study's findings can help scientists predict antimalarial drug resistance and prioritize experimental treatments.
Scientists have developed a novel enzyme, SUPer RNA EcoGII Methyltransferase (SUPREM), which can selectively modify RNA and has high methylation activity. This tool can be used to investigate RNA modifications in various diseases, providing new insights into their role in cell health.
A new study from the University of Leeds found that eating oily fish, fruits, cereals, and drinking moderate amounts of beer can lower the risk of rheumatoid arthritis. The research suggests that a tailored diet approach may be more effective for people with autoimmune diseases.
Researchers discover two distinct patterns of bipedalism among Pleistocene hominids in East Turkana region, suggesting contemporaneous use of lake habitats by different species. The findings provide evidence for the co-existence of multiple hominid lineages and challenge previous inferences based on fossil dates.
Researchers at Heriot-Watt University have proposed a new method to filter out daylight noise from quantum signals, enabling all-day satellite transmission. The approach uses time and phase encoding to overcome the issue, allowing SatQKD to operate during dawn and dusk hours.
Scientists at the Swiss Federal Laboratories for Materials Science and Technology have successfully created luminous wood by combining fungal threads with hardwood. The process involves a two-stage enzymatic reaction that stimulates the production of luciferin, emitting green light from the treated wood.
A new study by Killian McLoughlin and colleagues reveals that moral outrage evokes more sharing of misinformation on social media. Outrage-driven posts can spread misinformation as strongly as trustworthy news, with people sharing them without verifying accuracy.
Researchers create high-quality hexagonal boron nitride (hBN) films just one atom thick using a new growth method. The films exhibit excellent insulating properties and are suitable for high-performance electronic devices.
Researchers have developed a mathematical model that provides strong evidence for the cosmic censorship conjecture in three dimensions, suggesting singularities inside black holes will always be hidden. The model has implications for quantum gravity and advances efforts to understand thermodynamic properties of black holes.
Time-to-event (TTE) analyses in systematic reviews provide crucial insights but are often inadequately documented. A study of 100 reviews found inconsistencies and inadequate reporting standards. The authors suggest using methodological guidelines to improve the quality of TTE analyses.
Researchers identify caveolae's role in protecting adipocytes from rupture and inflammation; this discovery opens new avenues for treating metabolic diseases like obesity. The study highlights the importance of the caveolin-1 protein in maintaining cellular integrity.
Researchers found effective peptidomimetics that can bind to and inhibit Aurora-A's interaction with TACC3 without inhibiting its enzymatic function. This inhibition also showed promise in targeting a different protein-protein interaction between N-Myc and Aurora-A, which is crucial in childhood brain cancers.
A team of international scientists, including University of Michigan researchers, have discovered how ribosomes recruit to mRNA while it's being transcribed by an enzyme called RNA polymerase. This understanding holds great potential for developing new antibiotics targeting specific pathways in bacterial protein synthesis.
Dr Bøsch's work explores betalains' potential to impact blood pressure, diabetes, cardiovascular health, and gut microbiota. The award highlights the significance of her research in advancing functional food and feed applications with implications for human and animal health.
The United Nations has recognized the significance of agriculture in addressing climate change through its value chain approach. Small businesses play a crucial role in supporting small- and medium-sized farms by providing resources, training, and loans, leading to 'climate smart' practices.
Researchers have shed new light on gene expression by visualizing ribosomes in unprecedented detail. The study reveals a molecular mechanism for mRNA delivery to the ribosome, advancing our understanding of gene expression at the molecular level.
Extended Depth-of-Field Random Illumination Microscopy (EDF-RIM) offers a breakthrough in fluorescence microscopy, combining super-resolution with extended depth-of-field detection. This innovation allows for efficient imaging of large and complex 3D structures, minimizing light exposure and acquisition time.
The University of Leicester is collaborating with NASA to develop a novel Radioisotope Power System design and conduct laboratory tests. This collaboration aims to improve the efficiency of electrically heated simulators and Stirling convertor technologies, enabling spacecraft to venture into new frontiers. The project builds on previo...
Allophone children who attended preschool services show improved cognitive development, social emotional skills, and communication abilities compared to those who did not. Preschool education is a key factor in bridging the language gap for these children.
A new legal framework proposes addressing climate change through the lens of unjust enrichment, circumventing challenges of quantifying abstract harms and allowing for accountability without strict proof of wrongdoing. This approach offers a means to address environmental violations even when specific damages are difficult to establish.
The study utilized biocompatible polymethyl methacrylate microspheres for controlled antigen delivery, demonstrating improved immunogenicity of tetanus toxoid. Microsphere formulations showed significant immune response, with optimal polymer concentrations required to meet I.P. requirements.
A study found that cerebral stroke in hypertensive animal models impairs artery function and causes structural changes, including thickened walls and increased size. The use of suberoylanilide hydroxamic acid provided long-term protection against brain damage.
During winter hibernation, thirteen-lined ground squirrels reduce the activity of neurons in circumventricular organs, suppressing their sensitivity to physiological cues for thirst. This adaptation enables them to survive for months without drinking, despite their bodies crying out for water.
The project uses generative AI to examine whether scientific toolkits can help better study consumer behaviour in an effective way. By leveraging modern AI models and data from platforms like YouTube, researchers aim to extract meaningful patterns without needing to build a model from scratch.
A new study from Reichman University explores the impact of conflicting assessments on the FDA's role in regulating breast implants. The agency faces challenges in balancing the interests of the medical industry and public health, leading to underreporting and inconsistent enforcement of regulations.
New research shows that migrating marmalade hoverflies in the Pyrenees flew twice as far as non-migratory ones in the UK. The study found that stored energy in their abdomens is crucial for long-distance migration, and that throttle-speed can be more energy-efficient than flying faster.
A Curtin University study uses eDNA metabarcoding to track insect interactions with avocado flowers, detecting five times more unique pest species than digital video recordings. This method could help improve yields and make agricultural operations more efficient by identifying beneficial pollinators and pests.
CNIO researchers have identified significant inaccuracies in widely used epigenetic clocks, which are now being refined by the team. The new epigenetic clock model provides more accurate measurements, reducing errors by up to 25 years for some tests.
Researchers from Delft University of Technology have developed a new 3D electrode design for the Battolyser, enabling it to store twice the amount of electricity and charge four times faster. This innovative design reduces space and costs while producing green hydrogen comparable to existing electrolysers.
A study by the University of the Basque Country found that seven global nutrition labeling systems disagree significantly on assessing cooked dishes. The research suggests a need for developing new tools to evaluate food quality, taking into account local culinary and socio-cultural realities.
The German Research Foundation has approved renewed funding for SFB 1432 until 2028, expanding the project's scope to investigate fluctuations in ferroelectric and magnetically nonlinear materials. The team will also develop advanced mathematical analysis methods for complex dynamic systems.
Archaeologists have found evidence that Roman-era barbarian warriors used stimulants before battle, including small spoon-shaped objects attached to their belts. The researchers believe that these stimulants may have been widely used throughout history to motivate soldiers and reduce stress and fear during warfare.
Researchers developed miniature, multifunctional iontronic devices using biocompatible hydrogel droplets, outperforming previous soft iontronic devices. The dropletronics devices can interface with cells and record biological signals, offering a biocompatible approach to direct ionic communication.
A U-shaped association between waist circumference and all-cause mortality was found in women, while a J-shaped trend was observed in men with type 2 diabetes. The study suggests that optimal waist circumference thresholds for minimizing mortality risk are 107 cm for women and 89 cm for men.
Researchers designed DH-MTMs for self-powered wireless monitoring of water flow and structural deformation. The materials demonstrated high sensitivity, accuracy, and stability under various test conditions.
A recent study suggests coral heat tolerance adaptation may not keep pace with ocean warming, and some sensitive species may face extinction. The research modelled different climate scenarios, revealing that natural selection may be insufficient to ensure coral survival under expected warming levels.
Researchers analyzed seismic data from southern Israel and found weak ground motions caused by Hamas forces' unusual vehicle movement. This breakthrough highlights the potential of using seismic data to provide early warnings for future terrorist activities.
Scientists discovered iron sulfides could catalyze CO2 reduction into prebiotic organic molecules at high temperatures. The reaction was enhanced by sunlight and water vapor, suggesting terrestrial hot springs as a possible origin of life.
Scientists at Queen Mary University of London have developed a new material that creates synthetic heart valves as effective as native ones. The innovative material, created by Dr Roberto Volpe, has anisotropic properties that mimic natural tissue and can be fine-tuned for rigidity and flexibility.
A recent Lancet review highlights racial disparities in sudden cardiac arrest and death among athletes, with Black athletes facing a significantly higher risk. The study emphasizes the need for increased research into social determinants of health and adequate pre-participation evaluation to mitigate these disparities.
Theoretical physicists establish a close connection between quantum information theory and non-invertible symmetries in particle and condensed matter theories. A recent study proves that any non-invertible symmetry operation is a quantum operation, providing a general property of these operations.
A new study suggests that coral heat tolerance adaptation via natural selection may be insufficient to overcome the impacts of ocean warming, unless Paris Agreement commitments are realized.
The Eastern Tropical Pacific's Oxygen Deficient Zone (ODZ) expands and contracts every ten years, driven by Pacific decadal climate variability. This dynamic process has important consequences for marine ecosystems, as ODZs could respond quickly to climate changes.
The article presents SS-Pro, a simplified siamese contrastive learning approach for protein surface representation. The method leverages large unlabeled datasets for pre-training and fine-tuning downstream networks, achieving performance enhancements across various protein surface networks.
Researchers demonstrated the quantum optical properties of high-harmonic generation in semiconductors, aligning with theoretical predictions. The experiment showed entanglement and squeezing in the emitted light, which are key resources for many quantum technologies.
A research team has developed three new rice varieties resistant to bacterial leaf blight, a detrimental crop disease affecting smallholder farmers in East Africa. The varieties were created using marker-assisted backcross breeding and are expected to protect local rice harvests against aggressive strains.
Researchers found that immunosuppression in prostate cancer is associated with a specialised epithelial subtype. This interaction between the immune system and club-like epithelial cells can lead to treatment resistance in patients with advanced, treatment-resistant prostate cancer.
A machine learning algorithm developed by researchers at Aarhus University can identify patients at high risk of involuntary admission within six months. The study, based on electronic health record data, suggests that the algorithm can improve targeted treatment and prevention in psychiatric services.
Long-term hormone therapy in transgender individuals leads to significant changes in body composition and risk factors for cardiovascular disease. Transgender men experience increased muscle volume and abdominal fat, while women's muscle mass decreases, according to a new study published in the Journal of Internal Medicine.
Scientists develop high-performance Sb2S3 solar cells using additive engineering, achieving record-breaking 17.55% efficiency under 1000 lux illumination. The innovation enables sustainable power for IoT devices and holds promise for environmental-friendly energy harvesting.
The review explores the pathophysiological relationship between OSA and MetS, revealing a complex cycle of increased cardiovascular risks. Treatment options, including CPAP, weight management, and metabolic surgery, are discussed for improving patient outcomes.
Stanford Medicine researchers used a new gene-screening method to identify the CA12 gene as a key factor in doxorubicin-induced heart cell damage. They found that a drug called indisulam may be able to prevent this toxicity, and have tested it in mice with promising results.
The McCombs School of Business at UT Austin took first place in the National Real Estate Challenge, outperforming 18 other teams with a winning strategy focused on improving liquidity and optimizing the portfolio. The team won $12,500 and national recognition from corporate sponsors and judges.
Insilico Medicine has developed an innovative platform using generative AI to discover novel molecules. The company has nominated over 20 preclinical candidates and received IND clearance for 10 molecules.
The Institute of Open Science Practices (IOSP) is hosting its inaugural global conference, exploring cutting-edge scientific infrastructure and open science principles. Notable members will discuss technologies that make open science the default practice across diverse academic fields.
The University of Texas at Austin's McCombs School of Business has received a transformative gift from John and Candace Langston to establish the Langston Wealth Management Center. The center aims to transform the wealth management industry through student education, research, and industry partnerships.
Intracellular checkpoint molecules in NK cells, such as FBP-1 and EZH2, contribute to exhaustion, while TIPE2 and HIF-1α negatively regulate IL-15 signaling. Targeting these checkpoints may improve cancer immunotherapy outcomes.
32 UNC-Chapel Hill faculty recognized for broad influence in their fields, with multiple top-1% cited papers over the past decade. Researchers from 59 countries earn distinction, including those who moved to different institutions.