A recent study suggests that metabolic surgery can reduce the need for oral diuretics in patients with heart failure, resulting in a 65% decrease in diuretic use at 24 months after surgery. Patients who underwent metabolic surgery also experienced significant weight loss and improved quality of life.
A study by the University of Münster's research team led by Prof Markus Lappe found that smooth eye movements cannot be performed for all types of visual motion, leading to a disruption of spatial perception. The researchers also discovered that the compensation mechanism for rapid eye movements is overridden when certain non-rigid mov...
A new study found that COVID-19 travel restrictions and social measures reduced seasonal influenza cases globally, but allowed certain lineages to persist in tropical regions with fewer restrictions. The spread of influenza is closely tied to social behavior and air travel, which was severely impacted by the pandemic.
A new AI tool uses microbial communities as a 'microscopic fingerprint' to determine geographical source, opening up possibilities in medicine, epidemiology and forensics. The mGPS system achieves impressive precision, pinning down city sources for 92% of samples and distinguishing between handrails and kiosks in NYC.
Researchers found that hip implants with delta ceramic or oxidised zirconium head and highly crosslinked polyethylene liner or cup had the lowest risk of revision during 15 years after surgery. The study used data from over 1 million hip replacement patients in England and Wales to identify optimal implant materials.
Clinicians should avoid using 'never words' that can scare, offend, or diminish agency in patients and families dealing with serious illness. Researchers recommend alternative language and methods for clinicians to identify their own never words.
Researchers from the University of Nottingham have discovered how a chemical produced by a caterpillar fungus interrupts cell growth signals in cancer cells. The study shows that cordycepin, found in these mushrooms, can be an effective treatment for cancer, potentially causing less damage to healthy tissues.
Researchers identify biomarker Ki67 that indicates whether treatment with vedolizumab will be successful. The biomarker can help predict which patients are more likely to respond to the form of treatment, allowing for more targeted use and potentially improving patient outcomes.
Research analyzing European survey data from 113,884 men who have sex with men reveals that only 44% report being vaccinated against both hepatitis A and B. Strong public health support and creating an open environment are crucial to reduce outbreaks among MSM and eliminate hepatitis B.
Scientists from Duke-NUS Medical School have identified a genetic variation common among East Asians that contributes to drug resistance in cancer cells. The team's pioneering approach involves inhibiting the action of protein MCL-1, showing promising results in effectively killing resistant cancer cells.
The University of Kentucky survey found significantly higher dental decay rates for Kentucky children ages 2-5 compared to the national average. Demographic and geographic factors such as region, age, facility type, and rural location influenced tooth decay rates among the children screened.
Acute-on-chronic liver failure (ACLF) is characterized by metabolic alterations that disrupt immune function, contributing to disease progression. Metabolite imbalances, such as elevated lactate levels and reduced ketone bodies, further suppress immune responses.
A new study suggests that quieter zoo experiences can enhance visitors' understanding of animals and their habitats. By promoting silence, zoos can offer a more enriching experience for humans and non-human residents alike, while also restoring their original purpose as quiet spaces for contemplation.
The ECOG-ACRIN Cancer Research Group and PrECOG, LLC will present several abstracts at the 66th American Society of Hematology Meeting & Exposition. Promising results from a phase 2 study in acute myeloid leukemia and new data from the practice-changing E1910 phase 3 trial show improved outcomes for patients with B-cell acute lymphobla...
A new editorial suggests using syndemic theory approach to address disparities in COPD treatment, emphasizing the importance of considering comorbidities and socioeconomic factors. The authors aim to promote holistic care and increase research participation from minority populations.
Chemists at Emory University and Caltech have developed a revolutionary strategy for functionalizing carbon-hydrogen bonds, transforming low-cost materials into complex building blocks of organic chemistry. The breakthrough enables the synthesis of complex natural molecules with antimicrobial properties.
Researchers at University of Leicester developed a comprehensive fungal spore calendar to help patients manage symptoms through seasonal awareness. The study found two main peaks in spore concentrations: one in the summer and smaller peak in autumn, influenced by temperature and rainfall.
A new study reveals nearly one in five people in Small Island Developing States are exposed to coastal and inland flooding, trebling to over 60% in some countries. Climate change is exacerbating the risk of flooding across these nations, with even a 1.5°C increase projected to affect over 20% of populations.
Researchers developed an innovative automated wildlife camera network to monitor species in a Dutch coastal dunes nature reserve. The system, which combines autonomous cameras, wireless data transmission and AI-driven species identification, has been shown to be cost-efficient and efficient, providing new insights into the habitat use ...
The study analyzed antibody profiles from humans in three countries to reconstruct historical seasonal influenza patterns and individual lifetime infection histories. The findings revealed variation in incidence and antibody dynamics over the life course.
Researchers found that disrupting the hepatic vagus nerve restored balance to both liver and brain circadian clocks, leading to reduced overeating behavior in mice. Severing the nerve alleviated overeating caused by deleted clock genes, suggesting a key role for this neural link in obesity.
A geospatial analysis found that areas with more tanning bed facilities experience higher rates of melanoma. The study identified six high-risk clusters and seven low-risk clusters, suggesting a significant association between access to tanning beds and increased melanoma incidence.
A study by the University of Missouri School of Medicine found nearly half of opioid overdose patients tested positive for hepatitis C. The infection can cause chronic liver disease and even liver failure or cancer if left undiagnosed.
Researchers gather data from 400 women to analyze the effects and interactions of Bacterial Vaginosis on immune cells and vaginal tissue, hoping to develop more effective personalized treatments.
Two strains of pathogenic fungi cooperate to share insect victims, dividing territories and utilizing unique specialties. This peaceful coexistence allows them to partition limited resources and adapt to their environment.
Researchers developed a software tool called Perseus that identifies critical tasks in AI training and slows down processors not on the path, eliminating unnecessary power use. This approach saves enough energy to power 1.1 million US homes in 2026 and reduces AI's carbon footprint.
Scientists at Oak Ridge National Laboratory are studying how a new type of battery fails to improve long-term storage of wind and solar energy. By analyzing the failure mechanisms, researchers can design more durable solid electrolytes that support storing renewable energy for longer periods.
Researchers found that only 70% of examinees completed braille text reading tasks within the extended time limit, while none finished table reading tasks on time. The study highlights the need to reassess examination frameworks to better evaluate individual skills regardless of disability status.
A recent study published in Stem Cell Reports has found that brief exposure to certain 'danger signals' can prime the body's innate immune system, leading to a long-term hyperreactive and inflammatory state. This mechanism can help fight infections but also increases the risk of cardiovascular disease.
A pooled data analysis of 35 studies found that exercise-only interventions reduced the severity of depression and anxiety after giving birth, with a significant reduction in postpartum depression risk. The minimum threshold for achieving effects was at least 80 weekly minutes of moderate intensity exercise.
A proof-of-concept study has demonstrated that off-the-shelf thermoelectric generators can convert CO2 into useful fuels and chemicals. The temperature differences encountered in various environments, from geothermal installations to the Martian surface, could power this conversion.
New research reveals microplastics can act as ice nucleating particles, affecting cloud formation and potentially influencing weather forecasting and climate modeling. The study found that microplastics can trigger ice crystals to form at warmer temperatures, altering precipitation patterns and aviation safety.
Researchers propose that human culture is uniquely open-ended, enabling humans to communicate and understand an infinite number of possibilities. This contrasts with animal cultures, which have constraints that limit their evolution and development. By comparing human cultures with those of other species, including animals and non-huma...
Researchers at Tufts University and Vanderbilt University developed a biomarker to detect inflexible thinking in schizophrenia. The study found that people with schizophrenia generate unique neural patterns when making decisions based on conflicting information.
Ancient DNA from Pompeii's body casts reveals diverse genomic backgrounds and cosmopolitan ancestry, contradicting long-held assumptions about sex and family relationships. The findings highlight the importance of integrating genetic data with archaeological and historical information to avoid misinterpretations.
A study by Aliza Fleischer, Yadin Gindin, and Yacov Tsur from the Hebrew University of Jerusalem introduces a new model that integrates recreational freshwater ecosystem services into water allocation decisions. The researchers found that increasing demand for these services leads to significant changes in water diversion, with a 24% r...
Researchers discovered a connection between the liver's internal clock and feeding centers in the brain, revealing that targeting this pathway could help people with disrupted circadian rhythms manage their weight. The study found that cutting the nerve connection in obese mice restored normal eating patterns and reduced food intake.
Researchers have introduced a novel Janus channel of membranes (JCM) system that can simultaneously separate oil and water from complex emulsions. The system achieves impressive separation performance, with oil recovery of around 71% and water recovery of roughly 94% – both exceeding 99% purity.
A new plastic device has been developed to secure the surgical field during robot-assisted heart surgery, allowing surgeons to operate with greater independence. The device, made from a type of plastic used in medical implants and aerospace industry, expands to a certain size and retains its shape.
Researchers developed a new imaging technique using fluorescence-guided surgery to enhance visibility of tumors and nerves during head and neck cancer surgery. The technique uses two near-infrared fluorophores, one for tumors and another for facial nerves, allowing for clear differentiation between cancerous tissues and nerves.
The EVEREST project, funded by the EU, aims to standardize methods for isolating and characterizing extracellular vesicles. This could lead to non-invasive diagnostics and personalized therapies for complex diseases like cancer and cardiovascular conditions.
A new study published in The British Journal of Cancer found that whole genome sequencing can help identify treatment recommendations for cancer patients. The study evaluated the regional implementation of the 100,000 Genomes Project and found that different types of cancer were associated with varying rates of recommended actions.
Researchers developed a 36-gene predictive score that surpasses conventional methods in predicting tamoxifen treatment resistance. The polygenic score UAB36 has potential as a tool for personalized medicine, helping identify patients at higher risk of poor survival and suggesting alternative treatment strategies.
Scientists at WashU Medicine have successfully forced glioblastoma cells to display immune system targets, potentially making them vulnerable to immunotherapies. The strategy involves a combination of two FDA-approved epigenetic therapy drugs that induce the production of unusual proteins called neoantigens.
A significant increase in carbon dioxide emissions from private aviation has been found, with annual emissions rising by 46% between 2019 and 2023. The study also reveals that some individuals account for almost 500 times more CO2 emissions than the average person.
A recent study found that over a quarter of new mothers have fallen asleep while feeding their babies, increasing the risk of sudden infant death syndrome (SIDS). Researchers are urging care providers to inform new moms about the potential risks and provide guidance on safe feeding practices.
This special issue focuses on critical identification cases, emphasizing collaborative approaches and utilizing cutting-edge technologies. Research articles explore methods for re-associating fragmented remains, applying radiocarbon dating in forensic case work.
The new research highlights the complexity of plastics pollution, emphasizing its far-reaching effects on climate change, biodiversity loss, and freshwater usage. The study suggests a set of control variables to address plastics pollution in the Planetary Boundaries framework, promoting more sustainable responses.
A new study analyzed how seasonal flu viruses moved and evolved during the COVID-19 pandemic, finding that they remained in certain regions despite reduced global mobility. The study suggests increased genomic surveillance capacity will help monitor seasonal influenza to reduce vaccine mismatches and inform effective interventions.
A computer model developed by Kirsten Ten Tusscher's team provides fundamental insights into the control of plant thickness growth. The model found that overlapping gradients of chemical signals within the cambium layer guide stem cells to produce wood tissue, ensuring steady growth throughout a plant's life.
Researchers at Michigan Medicine found that SLC13A3 transporter impairs tumor immunity by endowing ferroptosis resistance. This discovery suggests a potential target for improving immunotherapy responses in cancer patients.
A team of researchers at Vanderbilt University has developed robotic sensory cilia that can monitor mucus conditions in human airways, detecting infection, obstruction, and disease severity. The technology leverages external magnetic fields to sense mucus viscosity and layer thickness, paving the way for real-time monitoring and early ...
Researchers from FSU and National High Magnetic Field Laboratory found that twisted bilayer graphene's conductivity depends on minute geometry structure changes upon interlayer twisting. The study reveals the potential of multilayer moiré systems in constructing materials with on-demand optical properties.
A new University of Cincinnati Cancer Center study reveals how copper helps clear cell renal cell carcinoma cells grow and advance. Copper accumulation is associated with worse outcomes for patients with ccRCC, and it boosts energy and growth in cancer cells.
A new study reveals that plant species invest less in defense to prioritize growth, with a negative correlation between defense genes and growth traits observed. Researchers identified significant variation among plant species in their investment in disease defense, using open databases to analyze 184 plant species.
Researchers at the ATLAS experiment have expanded their knowledge of Higgs boson interactions and found stronger constraints on 'new physics' phenomena. The study used machine learning to analyze data from the Large Hadron Collider, but no signs of unknown physics were detected.
A recent study by researchers from Zhejiang University and Nankai University estimates that AI systems could emit more than 102 million tons of CO₂ annually. The study analyzes energy consumption from 79 major AI systems between 2020 and 2024, highlighting the need for regulatory measures and standardized emissions caps.
A comprehensive analysis of 52,000 men with prostate cancer treatment found substantial long-term risks of urinary and sexual complications. Men treated with radiotherapy faced a threefold risk of bladder cancer diagnosis, while those who underwent prostatectomy had a sixfold increased risk of complications.
A new study by University of Arkansas researchers found that school suspensions and expulsions can lead to higher rates of depression through adolescence and into early adulthood. Adolescents who were suspended or expelled showed significantly higher depressive symptoms, which increased over time.
A longitudinal study found that bacteria associated with inflammation in the gut increases ten months before patients develop clinical rheumatoid arthritis. Researchers are exploring potential treatments at this early stage to prevent disease progression.