Northwestern University engineers developed the world's smallest pacemaker that can be non-invasively injected into newborn babies' hearts with a syringe. The device, paired with a wearable wireless controller, stimulates pacing through light pulses, dissolving after use without surgical extraction.
The Mount Sinai Hospital has launched an AI Small Molecule Drug Discovery Center to revolutionize the creation of life-saving medicines. The center will use cutting-edge AI to design and optimize novel therapeutics with unprecedented speed and precision.
Researchers from Vietnam, USA, Canada and Germany will discuss decolonization, cultural perspectives and daily lives under financial logic. The event features talks, readings and a panel discussion with renowned authors and artists.
The European HTA agencies and EMA have developed joint positions to address methodological challenges in assessing new drugs. Key findings include the need for randomized controlled trials and flexible study designs that can reduce sample size requirements and development timeframes.
Researchers found that Earth's first crust, formed 4.5 billion years ago, likely had chemical features similar to modern continental crust, rewriting the geological timeline. This suggests the distinctive chemical signature of continents was established at the beginning of Earth's history.
A new imaging technology has been developed that combines super-resolution imaging with artificial intelligence to reveal subcellular structures and dynamics in living cells. This breakthrough enables scientists to better understand the root causes of diseases, leading to improved treatments.
A recent Nature study found that human activities negatively affect wildlife biodiversity hundreds of km away, with only one out of five suitable species present in heavily impacted regions. Maintaining at least 30% pristine surrounding land supports conservation targets to protect about 1/3 of the land.
Three Taylor & Francis journals will be published open access in 2025 volumes with no cost to authors. Institutional support has reached the required threshold for the Subscribe to Open pilot, enabling OA publishing.
Researchers developed an integrated technology framework for urban transportation demand simulation and prediction. The framework incorporates various variables to capture inter-submodule interactions, achieving accurate predictions of up to 85%. It leverages spatiotemporal big data for fine-grained forecasts at a kilometer grid scale.
A scoping review of Rezum therapy for Benign Prostatic Hyperplasia (BPH) found that the treatment may improve or have no negative effect on erectile function in some cases. However, limitations were identified, including heterogeneity in patient demographics and follow-up periods.
Researchers explored how XR affects eating experiences, creating more attractive vegetarian food and improving satiety. The study used AR, VR, and MR to add pleasant fragrances and sensations, paving the way for more diverse and healthy food options.
Researchers found that NSD2 helps maintain MM cell identity by reorganizing DNA and influencing gene activity. This discovery could shape future treatment approaches for patients with t(4;14) myeloma.
A new study reveals that YTHDF1 plays a crucial role in suppressing immune-mediated liver injury and modulating inflammatory responses. YTHDF1 deficiency exacerbates liver damage, inflammation, and proinflammatory cytokine production.
The CONCERTO Project aims to advance the understanding and modelling of the terrestrial carbon cycle, reducing uncertainty in climate predictions. By integrating Earth observation data and innovative models, the project will contribute to improved climate policy and global efforts towards carbon neutrality.
Princeton neuroscientists pinpoint the central amygdala as the brain region responsible for forming lasting memories of food poisoning, which may shed light on PTSD and inform future clinical treatments. The study found that novel flavors can 'tag' specific brain cells to remain sensitive to illness signals.
Researchers at the University of Colorado Boulder have designed biodegradable press-on nails called Bio-e-Nails, made from algae or shellfish-derived ingredients. These customizable, colorful nails can be easily remelted and reshaped for new uses, promoting a more sustainable beauty industry.
A recent study published in Nature Communications found that exposure to phthalates during pregnancy can affect newborns' metabolisms and brain development. The study, led by researchers at Emory University, discovered that these chemicals can cross the placenta and impact baby's biology before birth.
KTU researchers have discovered an innovative solution to store excess heat underground, reducing heat loss and increasing energy efficiency. The ground-based heat accumulator stores heat in the soil, making it available when demand peaks, and can even reduce carbon dioxide emissions.
Researchers from Florida Atlantic University challenge the current aspirin guidelines based on a flawed trial, advocating for healthcare providers to make individual clinical judgments about prescribing aspirin. They stress that patients should consult their primary care provider to balance the benefits of clot prevention against bleed...
Researchers have developed a novel approach to detect Fusarium wilt in tomato plants by analyzing subtle changes in water use, allowing for early detection before visual symptoms appear. This method provides a quantitative approach to assess disease severity, pathogen virulence, and plant susceptibility.
A new study by UNSW Sydney researchers has discovered the sound frequencies of a cluster of stars 2700 light years away, allowing scientists to map the history of the Milky Way and other galaxies. The discovery uses oscillation frequencies to determine a star's age and mass, providing insights into galaxy formation and evolution.
A UC Irvine study found that machine learning algorithms using electronic health records can predict two-year dementia risk among American Indian/Alaska Native adults. The researchers identified novel predictors of all-cause dementia, including health service utilization.
A team of NYU computer scientists has developed a new blockchain system called Bounce that leverages satellites to ensure security, reduce energy consumption, and achieve low response times. Bounce processes over five million transactions per second, outperforming its nearest competitor by 30-100 times.
A study explores how large language models (LLMs) can transform teaching by generating customized educational materials, assessing student progress, and providing targeted feedback. LLMs excel at automating routine tasks, reducing teachers' workload and enabling them to focus on mentoring students.
A new study finds that increased screen time in teen girls leads to deteriorated sleep quality, with poor sleep mediating the association between screen time and depressive symptoms. Screen time also disrupts multiple aspects of the human sleep-wake cycle.
The Human Frontier Science Program has awarded 2025 Research Grants and Accelerator Awards to 104 of the world's most innovative scientists, spanning 30 nations. The grants support research on epigenetics, tick-borne diseases, and other life science topics.
Peyronie's disease is characterized by fibrous plaques leading to penile curvature and pain. Current management strategies focus on pain control and correcting deformity, with non-surgical treatments like traction therapy showing promise.
International team improves asteroid impact threat estimates from 3% to below 0.001%, with a new risk of 4% chance of impacting the Moon instead, threatening human space infrastructure.
Researchers developed an AI system, Plant Doctor, to monitor urban plant health at the individual leaf level using machine vision techniques. The system can automatically diagnose diseased areas on leaves and provide accurate diagnoses across various urban flora.
Low testosterone levels are linked to sexual dysfunction, decreased muscle mass, and increased risk of osteoporosis and metabolic disorders. Precision medicine offers hope in managing testosterone-related disorders through personalized treatment plans and biomarker-based diagnosis.
A new study reveals that tomato plants adapt to heat stress by delaying shoot apical stem cell development, allowing for stable yields. This redox-controlled mechanism enables the plant to temporarily suspend its maturation program during adverse conditions, resulting in significant yield losses prevention.
A French research team has discovered that an organogold(III) complex accumulates selectively in the mitochondria of lung cancer cells, demonstrating its potential as an anticancer treatment. The complex's antitumor activity is attributed to its interactions with specific biological molecules, disrupting their function.
A study found that alcohol consumption boosts the production of sex pheromones in male fruit flies, increasing their attractiveness to females and mating success. This effect is mediated by three neural circuits that balance attraction and aversion to avoid intoxication.
The partnership streamlines access to biodiversity data, enabling users to search and refine queries based on various criteria. Pensoft's hosted portals provide a scalable solution for 30 journals, fostering greater connectivity between scientific research and evidence.
A new compound has been discovered that shows neuroprotective and anti-inflammatory effects in two murine models of Alzheimer’s disease. The compound inhibits soluble epoxide hydrose (sEH), increasing levels of epoxyeicosatrienoic acids, which promote neuroprotection and reduce neuroinflammation.
A new study found that sending young women twice-daily text messages prompting them to reflect on fitness content significantly reduced social comparison, a key mechanism contributing to poor body image. However, the study also found no significant change in body appreciation scores.
A project aims to understand how temperature, light pollution, and bird abundance affect West Nile virus transmission in mosquitoes. The goal is to advise health departments on the best time to kill bugs and limit transmission.
Despite free treatment in many countries, TB patients incur catastrophic costs due to hospitalization and lost income. A systematic review found that these costs can be prohibitively high for individuals in low-, middle-, and high-income settings.
A new study published in Nature Medicine has investigated the potential of specific biomarkers to predict dementia risk up to ten years before diagnosis. The study found that low levels of certain biomarkers may rule out future dementia, but elevated levels alone are not reliable for identification.
A small study found 19 types of microplastic particles in cat placentas and fetuses during early pregnancy. The researchers suggest that microplastics may accumulate in cat placentas and potentially impact fetal health, highlighting the need for limits on plastic use and mitigation strategies.
A cohort study found early-life ozone exposure was associated with increased asthma and wheeze outcomes at ages 4-6, but not at age 8-9. Regulating ozone exposure may help mitigate the significant public health burden of asthma among US children.
A mass mortality event occurred in Triassic Wyoming, where dozens of giant amphibians called metoposaurid temnospondyls died together on an ancient floodplain. The study provides a unique snapshot of a single population and doubles the known number of individuals of the species Buettnererpeton bakeri.
A recent study by Chris O'Meara from the University of Exeter Law School argues that existing laws can be used to limit when and how states may lawfully target satellites using ASAT technologies. This could help address pressing international concerns regarding space militarization and the fear of wars between states.
Tadashi Isa returns to NIPS as director with goal to foster young researchers and maintain balance between cutting-edge research and collaborative studies. He aims to elevate physiological and neuroscience research in Japan to a world-class level.
The study found that almost 600 of the over 125,000 known fly species are likely to be migratory, highlighting their importance as pollinators, decomposers, and pest controllers. The review emphasizes the need for connected habitats to support flies along their epic journeys, as climate change and human impacts threaten many species.
Astronomers have discovered that stars in a specific region of our galaxy exhibit fluctuations in brightness, caused by 'starquakes'. These fluctuations can be translated into frequencies, providing clues about a star's age and properties. The study, led by Dr Claudia Reyes, offers new insights into how our galaxy formed.
The 2025 Schmidt Science Fellows will apply their knowledge to new fields, accelerating discoveries and driving breakthroughs. They will work on various problems, including developing smart artificial blood vessels for regrowth and real-time health monitoring.
Scientists successfully fermented miso on the International Space Station, discovering differences in bacterial communities and flavor profiles compared to Earth-made miso. The study's findings suggest that food fermentation can thrive in space, opening up new possibilities for astronaut well-being and performance.
Researchers develop sustainable passive cooling solution using mycelium-bound composites, outperforming conventional insulation materials in tropical climates. The 'fungi tiles' mimic an elephant's ability to regulate heat from its skin, improving cooling rates and thermal conductivity.
A recent study published in the Journal of Ageing and Physical Activity found that older adults exhibit similar or even less muscle damage than young adults after exercise. Muscle soreness was consistently lower in older adults, with reductions of around 34% at 48 hours and 62% at 72 hours compared to younger individuals.
Researchers have identified a new class of antibiotic that targets Neisseria gonorrhoeae, the bacterium causing gonorrhoea. The novel substance uses a unique mechanism to activate a self-destruction program in gonococci, killing the bacteria without harming other microorganisms or human cells.
Researchers warn of a growing crisis due to widespread availability and enticing marketing of nitrous oxide, also known as laughing gas. The number of hospitalizations and deaths attributed to its misuse have increased exponentially, posing significant public health concerns.
A new study models the demography of agricultural transitions, finding that population dynamics played a crucial role in the adoption of farming. The researchers used an ecological model to analyze interactions between farmers and hunter-gatherers, highlighting the impact of factors such as group migration and cultural assimilation.
A study found that spending on GLP-1 RAs increased from 2018 to 2023, with the largest growth rate between 2022 and 2023. The total spending on these medications exceeded $71 billion.
A recent discovery reveals that massive quiescent galaxies formed even earlier and more rapidly than previously thought. The study found a galaxy named RUBIES-UDS-QG-z7, which formed a stellar mass of over 10 billion solar masses within the first 600 million years after the Big Bang before ceasing star formation.
Tubular ectasia of rete testis (TERT) is a benign yet elusive condition linked to infertility. A 33-year-old patient with obstructive azoospermia was diagnosed with TERT after scrotal ultrasound and transrectal ultrasonography revealed extensive cystic changes in the rete testis area and patent vasa deferentia.
A coalition of sociological organizations led by the American Sociological Association condemns recent federal actions undermining academic inquiry and free speech. The letter urges university leaders, policymakers, and the public to resist efforts that harm individual researchers and diminish public knowledge.
Elite female athletes in the UK shared their experiences with pregnancy, citing a lack of guidance on nutrition and training that complements athletic ambition. They also expressed concerns about the impact of training on pregnancy and child development, as well as limited support networks within the sporting community.
Michigan State University researchers have created a new light-activated treatment for metastatic breast cancer, offering a targeted option with reduced side effects. The innovative cyanine-carborane salts work like a 'smart' bomb to kill cancer cells while sparing healthy tissue.
A study from the University of Vaasa examines the effects of insufficient sleep on work performance and presents practical methods for identifying and managing its impacts. Employees who suffer from fatigue should enhance their coping skills by scheduling tasks based on difficulty and slowing down their work pace.