Researchers at NUS have developed a non-invasive method to improve chemotherapy effectiveness while reducing side effects. By applying brief magnetic pulses, they demonstrated significant increase in doxorubicin uptake into breast cancer cells.
The study found that COVID-19-related disruptions led to frequent delays in investigations or treatments for children with brain tumors. Caregivers reported feeling traumatized by their experiences, including lack of access to healthcare facilities and social situations, which made it harder to evaluate their concerns.
A large study found that patients with diabetes taking GLP-1 receptor agonist drugs had lower rates of hospital readmission, wound re-opening, and hematoma after surgery. Improved blood sugar control was not the likely mediator, suggesting other mechanisms may be at play.
The 2024 Global Water Monitor Report reveals a worsening trend of intense floods, prolonged droughts, and record-breaking climate extremes. The report found that rising temperatures are changing the way water moves around the planet, with devastating consequences for human populations and ecosystems.
Researchers have mapped critical habitat characteristics for Canada lynx in western Colorado and southern Wyoming, revealing that over half of lynx habitats overlap protected areas. However, wildfire poses a major threat to lynx populations, with around one-third of potential habitat overlapping with disturbance areas.
The rollout of doxycycline as a prevention strategy for sexually transmitted infections (STIs) has shown promise in reducing syphilis and chlamydia rates, but its effectiveness on gonorrhea is limited. Close monitoring for antimicrobial resistance is necessary to ensure the long-term efficacy of doxy PEP.
Researchers have developed new models to explore the role of a membrane anchor on the folding and aggregation of PrP. Anchoring stabilizes folding and inhibits aggregation, with clumping induced by pre-formed aggregates, suggesting a potential mechanism for infectious prion diseases.
The January 2025 themed issue of Speculum reflects on the evolution of medieval studies, highlighting shifts toward global perspectives, feminist scholarship, and decolonization. The issue offers histories of para-academic groups, such as the Society for Medieval Feminist Scholarship, BABEL, and the Material Collective, and critiques t...
Scientists studied ancient whitebark pine forest on Beartooth Plateau, finding the tree line was 600 feet higher during a moderate climate period. The discovery sheds light on how dynamic ecosystems respond to temperature warming and offers insights into future changes for alpine environments.
The study reveals that directional connections propagate signals in a downstream flow, leading to more complex activity patterns. Mathematical models also suggest that modularity and connectivity interact to foster dynamical complexity.
Organoids, derived from stem cells, closely mimic human tissue for biomedical research and drug testing. Standardization is crucial for generating reliable results in organoid construction, requiring approved operating procedures and informed consent from donors.
Researchers found a core-collapsing self-interacting dark matter subhalo is responsible for the peculiar spur and gap features observed in the GD-1 stellar stream. This discovery provides insights into the nature of dark matter itself and offers a new explanation for the observed perturbations.
Weill Cornell Medicine has received a $2.3 million CDC grant to enhance care coordination for young breast cancer survivors, focusing on racially and socio-economically diverse groups to reduce symptom burden and improve survival outcomes.
A new study from Harvard T.H. Chan School of Public Health and colleagues reveals that less than 0.1% of privately insured US adolescents receive puberty blockers or gender-affirming hormones. No TGD patients under age 12 were prescribed hormone treatment, indicating low access to care among this population.
A study investigated gene-chemical interactions on bacterial growth, revealing varying impacts of chemicals depending on sugar presence. Machine learning analysis found a countervailing effect between genetic and environmental changes, suggesting a strategy for bacterial survival in nature.
The BfR is seeking experts from biochemistry, medicine, toxicology, pharmacology, statistics, and sociology to advise on risk assessment issues. The selected scientists will contribute their expertise to the commissions for a four-year term.
The study introduces Flexible-Spoke, Non-Pneumatic Tyres as a solution for manual wheelchair users. These tyres absorb impacts and vibrations, offering enhanced comfort and reduced weight compared to conventional options.
A new study found that intensive farming and shallow groundwater in the US Corn Belt increase precipitation recycling by almost 30%, providing a significant boost to rainfall during the growing season. The research, published in PNAS, used advanced computer modeling techniques to quantify the impact of these factors on regional climate.
A $5 million NIH grant will support research on the causes of chronic post-surgical pain, with the goal of developing personalized risk-assessment, prevention, and management tools. The study will examine genetic, molecular, neuro-immune, and behavioral patterns in over 300 surgery patients to identify key contributors to pain.
A new method called Annotatability helps identify mismatches in cell annotations and better characterizes biological data structures. This approach enables more precise downstream analysis of biological signals, capturing cellular communities associated with target signals.
Researchers at UTHealth Houston have discovered two novel genes, DYRK1A and EGFR, linked to genetic mutations causing epileptic brain lesions. This breakthrough offers a new framework for understanding epilepsy and developing targeted therapies.
Physicists at MIT have devised a formula predicting which invasive species will succeed in an ecosystem, based on analysis of soil bacteria. The researchers found that population fluctuations are key to invasion success, and that diversity can either help or hinder the invader.
Researchers have developed a way to detect circulating tumor cells in the bloodstream using biolasers, which can provide valuable information about the DNA organization inside cancer cells. The technique has been successfully tested on pancreatic and lung cancer patients, showing high accuracy rates of up to 99%.
A new study found that nearly two-thirds of schools in Chicago's Englewood neighborhood had at least one gun incident within 400 meters of where children were walking home during the 2021-22 school year. The researchers used acoustic sensors to detect gunshots and found that children are exposed to violence on their way to and from sch...
Researchers developed a high-power tunable laser on silicon photonics, reaching close to 2 Watts of output power. This achievement has the potential to disrupt the field of photonics and enable large-scale deployment of integrated photonics systems.
A new model for treating loneliness in borderline personality disorder suggests extending treatment beyond therapeutic relationships to foster social connections with others. This approach aims to provide patients with a sense of self and improve functional roles, promoting overall well-being.
A recent case series suggests that an extended course of Paxlovid may help some patients with long Covid experience sustained improvements in their symptoms. The study, published in Communications Medicine, found that five out of 13 patients experienced significant symptom relief after taking the antiviral drug for 15 days.
A new study by KAUST researchers predicts that the Arabian Peninsula will experience extreme temperature rises, with some areas warming three times faster than global averages. The findings highlight the urgent need for good climate policy to mitigate the effects of climate change in the region.
Researchers propose a novel two-branch network to decompose visual changes into speech-relevant and speech-irrelevant components. By introducing high-frequency audio signal guidance, the method learns discriminative disentangled speech representations for lip reading tasks.
A novel nitrogen-doped porous carbon material improves lithium-sulfur battery performance by increasing sulfur loading and reducing lithium polysulfide migration. The battery achieves a high capacity of 705 mAh g⁻¹ under rapid charging conditions, demonstrating excellent stability.
Researchers analyzed data from 12,794 participants and found that those who experienced childhood maltreatment were three times more likely to experience intimate partner violence at age 21. The risk continued to grow over time, with a four-fold increase by age 26.
NRG Oncology has established a new Theranostics Subcommittee to develop a more robust theranostics program within its portfolio. The subcommittee will serve as a resource for research investigators and collaborate with other organizations to enhance the effects of treatment on targeted cancer.
Research by Stephen Shea and Alexandra Nowlan reveals that smell and hearing signals merge in the brain's auditory cortex during pup retrieval, a crucial maternal behavior. This study may provide insights into how autism affects social cue interpretation and offer new avenues for understanding human connection.
A new study by Columbia University Mailman School of Public Health evaluated the career services programs and employment outcomes of its graduates. The study found that neither program usage nor employment outcomes were statistically different by race or ethnicity, with room for improvement in other areas.
Researchers from Singapore, Japan and US developed an advanced swarm navigation algorithm for cyborg insects that prevents them from getting stuck in challenging terrain. The new algorithm represents a significant advance in swarm robotics and could pave the way for applications in disaster relief and search-and-rescue missions.
A recent study published by Dr. Matthew Nystoriak of Masonic Medical Research Institute has uncovered groundbreaking insights into heart health. Elevated levels of β-hydroxybutyrate, a ketone body produced by the liver, have been shown to improve cardiac blood flow and reduce ischemic heart disease.
New research reveals widespread resistance to benzimidazole-based dewormers among canine hookworms in Australia. This increases the risk of gastrointestinal parasites, anaemia, diarrhea, and malnutrition in dogs, as well as cutaneous larva migrans disease in humans.
A new study published in Atmospheric and Oceanic Science Letters explores the relationship between meteorological conditions and PM2.5 concentrations, finding that wind speed, temperature, and humidity play a crucial role in pollutant accumulation and dispersion. The joint data assimilation system developed by the research team improve...
A study by North Carolina State University found that 24% of developed land in the US is within 250 meters of a 100-year floodplain, despite efforts to reduce flood risk. This 'safe development paradox' creates a false sense of security, leading to increased development in areas threatened by flooding.
Dr. Marco Demaria joins Aging-US as Editor-in-Chief with expertise in cellular senescence and aging research. He aims to develop new therapeutic approaches to mitigate age-related diseases.
A large-scale study analyzed the gut microbiomes of over 21,500 individuals and found that vegan diets had the healthiest microbiomes, followed by vegetarians and omnivores. The researchers discovered unique microbial signatures for each dietary pattern, with vegans having more beneficial bacteria associated with fiber fermentation.
Researchers observed a galaxy nearly 6.5 billion light-years away, revealing a large number of individual stars made visible through gravitational lensing. The discovery provides new insights into the universe's greatest mysteries, including dark matter and stellar populations.
CircRNAs regulate cellular events, modulate signaling pathways, and contribute to drug resistance. Monitoring their expression levels can help assess treatment response and predict clinical parameters.
A systematic review of randomized controlled trials found GLP-1 RAs and co-agonists to be effective for weight loss in adults with obesity, including promising options not yet FDA-approved. The study also showed similar safety profiles across agents, with mild gastrointestinal side effects being the most common.
Researchers developed a novel strategy to synthesize single-crystal sp²c-COFs, which exhibit enhanced electronic conductivity and magnetic properties compared to classical COFs. The synthesized single crystals show room-temperature metal-free ferromagnetism, addressing the bottleneck in synthesizing single-crystal COFs.
The 2025 SSA Annual Meeting will present 48 technical sessions covering topics like earthquake forecasting and ocean-bottom seismology. Working journalists can register for free access to plenary talks and poster sessions.
The Microelectronics Energy Efficiency Research Center for Advanced Technologies (MEERCAT) will focus on energy efficiency, exploring solutions that bridge sensing, edge processing, artificial intelligence and high-performance computing. Sandia is leading one of the eight energy efficiency-related research projects within the center.
A study in Nature Medicine reveals large floods are associated with higher death rates from major mortality causes, including infectious diseases and cardiovascular conditions. Floods disproportionately affect older people and females, with increased risks of injury deaths and neuropsychiatric conditions.
Researchers at McMaster University discovered a critical vulnerability in drug-resistant bacteria: zinc deficiency. By depriving bacteria of zinc, they found that it becomes vulnerable to azithromycin, an existing antibiotic. This study opens the door to new clinical utility for old drugs and cementing nutrient stress as a viable path ...
The study analyzes 40 years of climate data to identify trends in six metrics impacting apple growth, including extreme heat and cold days. The top three largest apple producing counties in the US are among the most impacted, with Yakima County facing significant challenges.
A single iron infusion in the third trimester significantly reduces anaemia in pregnant women, with a lower prevalence at delivery compared to iron tablets. The treatment also boosts iron stores postpartum, offering a potential game-changer for maternal care and birth outcomes worldwide.
Researchers develop core-membrane microstructured amine-modified mesoporous biochar for efficient CO2 capture, demonstrating exceptional sorption capacity and thermal stability. The innovative material shows promise in mitigating climate change through cost-efficient and sustainable CO2 capture technologies.
The study explores how light energy can induce thermal expansion and mechanical deformation in semiconductors, enabling precise control over material properties. This research has the potential to advance sustainable energy technologies and reduce environmental impact of electronic devices.
A new study reveals that nutrient enrichment driven by agriculture and fossil fuel combustion poses a significant risk to tropical forest dynamics. This phenomenon can disrupt forest composition and resilience, particularly in the face of global climate change.
Research on hornwort genomes uncovers the secrets of plant evolution, revealing stable autosomes despite deep evolutionary history. The study also identifies dynamic accessory chromosomes and potential sex chromosomes, providing insights into plant reproductive strategies and adaptation to environmental challenges.
Researchers have identified clinoptilolite and biochar as cost-effective options for removing siloxane compounds from landfill gas. These natural materials can enhance the performance of adsorbents with modification techniques, offering an environmentally friendly solution to mitigate damage to energy equipment.
Researchers will analyze tissue samples from 100 patients over three years to understand why some respond better than others to biologic and targeted therapies. The study aims to improve matching of treatments to individual patients, reducing the guesswork and cost associated with ineffective treatment.
A recent study has uncovered the crucial role of enzyme G6PC2 in regulating blood sugar levels by controlling glucagon secretion from pancreatic alpha cells. Genetic variations in G6PC2 impact its expression in alpha cells, and inhibiting this enzyme may provide a new therapeutic strategy for type 2 diabetes.
A new study has found HSV-1 proteins embedded in Alzheimer's brains, linking the virus to tau protein changes. Researchers suggest that inhibiting viral activity or modifying the brain's immune response could slow or stop Alzheimer's progression.
Researchers develop strategies to address mechanical and electrical properties, implantation, and multimodal functionality in hydrogel-based bioelectronics. The team explores conductive polymers, stimuli-responsive hydrogels, and wearable/implantable devices to create seamless human-body interfaces.