Researchers found that Finnish mothers who had more children during periods of famine lived shorter lives, with each child shortening their mother's lifespan by half a year. The study suggests that reproductive effort can affect human aging under harsh conditions.
A new study confirms that Saturn's icy moon Enceladus has significant heat flow at its north pole, overturning previous assumptions and strengthening the case that it could support life. The sub-surface ocean is believed to be one of the best places in our solar system for life to have evolved outside Earth.
Researchers at UT Health San Antonio School of Dentistry are studying novel targets and approaches to treat oral squamous cell carcinoma, the most common type of oral cancer. The studies aim to reduce pain management and mucositis in patients undergoing radiotherapy.
Researchers have reviewed ceramic-based electromagnetic interference (EMI) shielding materials to optimize their electrical conductivity and microstructural design. The team emphasizes the need for comprehensive evaluation of synergistic interactions among electrical conductivity, dielectric properties, and microstructural characterist...
Research highlights the importance of mitochondria-endoplasmic reticulum cross-talk in colorectal cancer, regulating Ca2+ homeostasis and lipid metabolism. Novel therapeutic strategies targeting this crosstalk may suppress CRC progression and improve patient outcomes.
Researchers investigated GnT-V, a cancer-related glycosylation enzyme, and found its selectivity relies on protein structure and subcellular trafficking. Two enzymes, metalloproteases, were identified as major substrates in the kidney.
Researchers at University of Würzburg successfully tested an AI-based attitude controller for satellites directly in orbit, using Deep Reinforcement Learning. The test demonstrated the speed and flexibility of the DRL approach, which can automate control strategies and adapt to differences between expected and actual conditions.
Researchers at Michigan State University have uncovered the secrets of a native Death Valley plant that thrives in extreme heat. By studying Tidestromia oblongifolia, scientists have discovered a blueprint for engineering crops that can adapt to high temperatures, potentially transforming agriculture in a hotter world.
Researchers reveal how single genes producing multiple proteins impact health and rare diseases, providing a new understanding of genetic mutations and their effects. The study identifies cases where mutations affect only one protein, leading to distinct symptoms and severity.
A study by Brown University and Harvard University found that premature deaths among adults aged 18-64 increased by 27% from 2012 to 2022, with Black Americans facing a 38% higher rate. This trend prevents many from accessing Medicare benefits, highlighting the inequities in the social safety net.
A new radioimmunotherapy approach has been developed to treat HER2-positive breast cancer, resulting in complete and histologic cures with minimal toxicities. The treatment uses a pretargeted approach to directly target tumors, reducing the risk of radiation toxicity to healthy tissues.
Researchers from China have developed a bistatic dual-comb ranging approach that achieves nanometer-level absolute distance measurement over 113 kilometers, surpassing previous limitations. This technology provides breakthrough technical support for large-scale space research programs.
Cambridge scientist Dr Chris Macdonald creates the most effective treatment for public speaking fear using VR overexposure therapy. The platform has demonstrated remarkable results in reducing anxiety and improving performance.
Rice University researchers outline emerging solutions to make graphite production cleaner and more resilient, including synthetic graphite from renewable sources. The study emphasizes the critical role of graphite in energy storage technologies and the need for sustainable supply chain management.
Scientists from Rockefeller University have developed a powerful upgrade to IVIG therapy, an engineered antibody that delivers the effectiveness of IVIG at a fraction of the dose in mice. The new molecule is synthesized without human plasma and has shown significant improvement over current IVIG treatments.
The SQUIRE project deploys quantum spin sensors on the China Space Station to search for pseudomagnetic fields induced by exotic interactions. These interactions can induce energy shifts in atomic energy levels, which can be detected as pseudomagnetic fields by quantum spin sensors.
Researchers at Arizona State University discovered that SerpinB3 plays a natural role in the body's wound-healing process, helping skin recover after damage. The protein helps activate keratinocytes to rebuild tissue and improve skin strength.
Researchers from Nantong University have discovered four new species of Lepidosira springtails in China, representing the first record of this genus in the country. The findings, confirmed by molecular and morphological analysis, expand scientific understanding of springtail diversity and evolution.
A team of researchers from LMU München investigated why CO2 fluxes from land use are uncertain and how they can be estimated more accurately in the future. They found that differences in definitions, data sources, and model assumptions lead to substantial discrepancies and uncertainties.
Researchers have discovered a new way to make valuable industrial chemicals from propylene using lead dioxide as a catalyst. The oxygen atoms inside the catalyst play an active role in the chemical reaction, making it more sustainable and affordable. The study's findings were published in Catalysis Science & Technology on October 7, 2025.
A free webinar explores the relationship between sleep and borderline personality disorder, featuring preliminary results from a clinical trial on the effects of a single-session sleep intervention. The study suggests that optimized sleep habits could be a crucial factor in preventing BPD symptoms.
A global study found that crop rotation increases total yields, energy and protein content, and micronutrient levels in crops such as iron, magnesium, and zinc. The practice also leads to higher farm revenues and less year-on-year yield variability compared to continuous monocultures.
Researchers have developed particles that can deliver an effective immune response at a much lower dose than traditional mRNA vaccines. The new particles, called AMG1541, use cyclic structures and ester groups to enhance mRNA delivery and improve biodegradability. This could potentially reduce vaccine costs and side effects.
A new study from the Complexity Science Hub found that European cities with a metro system have a significant reduction in car use, with an average of 37% of car trips compared to 50% in cities with only trams and 54% without rail. In contrast, tram cities show no measurable impact on reducing car use.
A study reveals how colorectal tumors use TGF-β to prevent immune cells from reaching and attacking the tumor. The researchers suggest strategies to improve immunotherapy efficacy by blocking this dual barrier and identifying new therapeutic targets.
Research reveals that early Holocene ice-shelf retreat in East Antarctica was driven by oceanic forcing enhanced by meltwater discharge from neighboring regions. This self-reinforcing feedback loop accelerated inland ice loss, indicating that Antarctic ice retreat can propagate across multiple sectors through oceanic connections.
Researchers have demonstrated that non-circular VCSEL cavity designs can fundamentally improve performance by redefining boundary conditions. The pentagonal VCSEL showed over twice the power density of traditional circular VCSELs, while the mushroom-shaped VCSEL offered high power and low spatial coherence.
Researchers developed a new deep learning method that boosts microplastic classification accuracy using the attention mechanism, outperforming traditional algorithms. The method achieves a classification accuracy of up to 98%, optimizing the model's performance and extracting more spectral features.
A research team from the Chinese Academy of Sciences found that lunar surface water has a global source in the solar wind, with its distribution mainly controlled by latitude and regolith maturity. The study used samples from China's Chang'e-6 mission and NASA's Apollo missions to analyze the abundance and origin of lunar surface water.
Scientists uncover a previously unknown function of the enzyme NUDT5, which acts as a molecular scaffold to control purine synthesis and DNA replication. This discovery sheds light on why some patients respond better to long-used cancer drugs.
A University of Houston biologist has received a $2.16 million federal grant to study how some coastal frogs survive in salty environments. The research could reveal how cells cope with salt stress and have implications for understanding the health risks of high-salt diets in humans.
A new study from the University of Lübeck introduces a 'lottery-first' approach to research grant allocation, increasing female representation by 10% and funded projects led by women by 23%. This method reduces estimated economic costs by two-thirds while maintaining scientific excellence.
Research detects three species of Rickettsia bacteria in dog ticks in Malawi, highlighting a significant knowledge gap and potential public health risk. The study suggests that dogs can serve as sentinel animals for detecting pathogens, emphasizing the importance of integrated surveillance approaches to understanding zoonotic diseases.
A new international study published in Insect Science offers a more complex picture of insect populations. High-flying migratory insects have remained largely stable over nine decades, but agricultural pests are on the rise, posing a persistent threat to food security.
Despite progress in controlling stomach, liver, and esophageal cancers, China's total cancer deaths continue to rise, projected to reach 2.4 million by 2030. Population aging and unequal access to healthcare drive these increases, with rural areas lagging behind urban regions.
A new rain correction approach using dual-frequency measurements from the WindRAD instrument aboard the FY-3E satellite significantly improves wind measurement accuracy during moderate rainfall. The method reduces wind speed root-mean-square errors by approximately 0.2 m s−1 and wind direction errors by about 1.6°.
Researchers developed a novel immobilization strategy for surface plasmon resonance (SPR) assays of membrane proteins, effectively addressing technical constraints. The approach allows stable and specific capture of membrane proteins on sensor chips, enabling precise quantification of binding kinetics.
Researchers developed a novel hydrogel that leverages radiative and evaporative cooling to efficiently manage heat in harsh outdoor environments. The breakthrough design offers enhanced fire safety and water autonomy, promising significant advancements in thermal management.
A new AI model uses machine learning to predict drug toxicity in humans by identifying biological differences between cells, mice, and humans. The model improved predictive power over existing state-of-the-art models and demonstrated practicality in predicting market withdrawal due to toxicity.
Researchers developed microalgal-bacterial granular sludge to efficiently degrade estrogenic compounds from wastewater. The system achieved up to 98% removal of estriol in low doses and adapted to repeated exposures.
Researchers used grocery store purchase data to identify areas with nutritionally deficient diets, focusing on low-income and minority communities. The study found that neighborhoods in London's east and northwest had high-sugar and high-carbohydrate purchases, suggesting residents were not accessing a nutritious diet.
The study found that a nine-month programme of supervised exercise improved muscle mass and strength, particularly in the arms and legs, and physical performance in patients with breast cancer that had spread to other parts of the body. Muscle mass increased by an average of 0.79 kg after three months and 0.32 kg after six months compa...
Researchers have discovered a single organic molecule can induce the Kondo effect, challenging long-held beliefs that it requires vast metallic electrons. The cobalt phthalocyanine molecule creates a 'molecular Kondo box' by hybridizing with conduction electrons of an underlying metal substrate.
Researchers developed a novel electrocatalyst with double heterojunctions that enhance oxygen reduction and oxidation reactions, improving lithium-oxygen battery performance and stability. The discovery paves the way for scalable and efficient high-performance lithium–oxygen batteries.
Dr. Lovly brings nearly two decades of experience in clinical care, research and academic leadership to her new role, shaping the modern landscape of lung cancer care. Her expertise in precision medicine will be instrumental in accelerating progress for patients with lung cancer across the country.
A new national quality framework has been developed to evaluate medication management and clinical services provided by pharmacists in residential aged care. The PHARMA-Care National Quality Framework promotes a transparent, person-centred approach to medication management, aiming to reduce risks linked to polypharmacy.
UCLA researchers create optical processor that performs massive parallel computation of nonlinear functions, executed rapidly and simultaneously at extreme spatial density. The study demonstrates the use of diffractive optical processors to approximate arbitrary sets of bandlimited nonlinear functions.
Researchers at Hefei Institutes of Physical Science developed an ultra-compact excimer laser, eliminating mechanical gas pumps and reducing system volume. The laser achieved outstanding energy stability with a pulse energy exceeding 2 mJ while maintaining energy stability.
Higher levels of urban greenness are associated with a 7% reduction in hospital admissions for all cause mental disorders, with stronger associations for substance use disorders and psychotic disorders. The study suggests that greater exposure to greenness increases the protective effect on mental health.
Engineered biochar emerges as a powerful tool to combat water pollution, removing hazardous substances from wastewater. Its tailored surface chemistry and structure make it an ideal candidate for environmental cleanup, capturing both heavy metals and organic contaminants simultaneously.
A recent study revealed sharp increases in mental distress among international students in the US, with anxiety rising from 20% to 36%, depression from 20% to 35%, and suicidal ideation from 5% to 10%. Despite modest increases in counseling services, the gap between psychological needs and access to care remains significant.
Researchers identified NUDT5 as a structural regulator that controls purine synthesis by physically restraining the key biosynthetic step. This mechanism may also explain cancer drug resistance and informs new therapeutic approaches for diseases caused by MTHFD1 deficiency.
Plant biologists developed a method to grow transgenic plants in weeks instead of months by hijacking a plant's natural regeneration abilities. The technique uses bacteria carrying genetic instructions for wound healing and regeneration to trigger plant growth.
The BioHub aims to complete over 24 pilot projects, train over 500 individuals, and create 3,000 new jobs within three years. Powered by breakthroughs in genetics, genomics, process engineering, and artificial intelligence, Central Massachusetts is poised to lead a new era of biology-based manufacturing.
Researchers used high-resolution imaging to map brain regions involved in regulating body's energy needs and sensing internal conditions. The study replicated previous findings and expanded upon them, confirming connections between brain areas that help manage the body's needs and sense what's happening inside.
Researchers found that selective enrichment of adhesion proteins like fibronectin and vitronectin maximizes optimal cell adhesion on plastic surfaces. The optimal UVO treatment time creates a mix of hydrophilic and hydrophobic regions, promoting attachment protein replacement and secure cell binding.
Japanese primary care physicians derive a sense of meaning from managing diverse health problems, fostering rapport through continuous care, and collaborating with other healthcare professionals. These experiences promote professional growth and contribute to broader societal goals, building fulfilling careers.
Eczema's duration and severity significantly impact a child's likelihood of outgrowing food allergies. Children with longer-lasting, more severe eczema are less likely to overcome food allergies.
Researchers at New York University have discovered gyromorphs, a new class of materials that outperform existing structures in blocking light signals. These materials have the potential to revolutionize light-based computers by maintaining signal strength and enabling faster calculations.
Microbial metabolites from the gut microbiome influence gene expression, cellular function, and host health. The MDME axis proposes a unified theoretical framework explaining this complex dialogue.