Researchers identified a genetic inflammatory signature that defines specific depression subtypes and influences antidepressant outcomes. Higher CRP polygenic scores were associated with reduced weight and appetite loss, earlier age of onset, and lower employment status after treatment.
A new study suggests a greater focus on hormone changes when diagnosing and treating TBIs in menopausal women, as researchers identify significant symptom overlap between TBIs and menopause-related conditions. The study proposes the development of a more comprehensive hormone-informed questionnaire to capture sex-specific symptom profi...
A new fabrication method using photolithography template-assisted processing (PTA) enables high-resolution full-color Micro-QLED devices with pixel sizes ranging from 2 to 20 μm. The technology demonstrates outstanding performance with 1184 ppi resolution and brightness over 10,000 cd/m².
Researchers developed a machine learning-driven design for a high-energy NASICON cathode that surpasses previous materials in terms of specific capacity, average operating voltage, and rate capability. The new cathode addresses sustainability concerns by replacing toxic vanadium with more environmentally friendly elements.
A new photonic chip called Gezhi achieves record-breaking speeds of 25 million images per second and consumes ultra-low light levels. This technology holds immense potential for large-scale expansion and high-performance applications in AI, autonomous driving, smart healthcare, machine vision, and language models.
Researchers developed a novel MoOX/Ag/MoOX sandwich-structured buffer layer to improve semi-transparent CsPbI₃-based perovskite solar cells and four-terminal tandem solar cells. The MAM buffer layer enhances light transmittance and charge carrier transport, achieving high efficiencies of up to 26.55% in 4-T tandem minimodules.
A periodized exercise program can improve physical function, reduce treatment-related fatigue, and enhance overall quality of life for cancer patients. Research shows that tailored exercise plans can also positively influence systemic inflammation, metabolism, and immune function, which could impact cancer progression and recurrence.
Researchers found that a pyrite-oxidizing microbe preserves up to 90% of atmospheric oxygen in sulfate, offering insights into microbial activity in ancient environments. This discovery could help analyze oxygen isotope data from Martian sediments for signs of life and provide clues to environmental conditions on early Earth.
Researchers developed a method to control crystal growth and orientation, leading to higher efficiency (25.85%) and improved stability under humid and thermal conditions. The in-situ reaction promotes directional growth, larger crystal sizes, and suppressed defect states.
A recent study published in the European Heart Journal found that female bodybuilders are at a high risk of sudden cardiac death, with a mortality rate 20 times higher than amateur athletes. The study also revealed a significant proportion of deaths from suicide and homicide.
A healthy microbiome promotes overall well-being, influencing areas like cognition, mood, immunity, and disease susceptibility. By incorporating proven dietary interventions, regular exercise, stress reduction, and adequate sleep, individuals can harness their microbiome for optimal health.
A new study reveals that middle-class Mancunians, including doctors and engineers, lived alongside working-class residents in the same buildings and streets. The research found that over 60% of buildings housing wealthy occupational classes also housed unskilled laborers.
The winners of the Applied Microbiology International Horizon Awards 2025 have been recognized for their groundbreaking contributions to global challenges through applied microbiology. The awards celebrate excellence across various domains, including drug discovery and sustainable agriculture.
Workers in Bangladesh's garment factories often face temperatures above 35°C, causing dehydration, heat exhaustion, and reduced productivity. Simple cooling solutions like insulated roofs, fans, and drinking water access can reclaim lost work output, improving worker health and wellbeing.
A*STAR researchers discovered that mosquito saliva not only transmits the virus but also influences how the body's immune system responds to chikungunya infection. Sialokinin, a bioactive peptide in Aedes mosquito saliva, binds to neurokinin receptors on immune cells and suppresses monocyte activation.
A study published in the Journal of Clinical Endocrinology & Metabolism found that people with higher muscle mass and stronger handgrip are less likely to progress to obesity, organ issues, or death. Grip strength was consistently associated with lower risk across multiple muscle metrics.
A surveillance study found that cancer incidence rates for 13 types of cancer rose in both younger and older adults worldwide, with increases related to obesity. This analysis suggests that research priorities should consider cancer types seen rising in both age groups.
A new study projects that US funding cuts will result in a catastrophic effect on pediatric TB, with children in Sub-Saharan Africa and Southeast Asia experiencing a significant spike in preventable cases and deaths over the next decade. The loss of US bilateral health aid is projected to result in an additional 2.5 million pediatric T...
A phase 1 trial has investigated the combination of a ribonucleotide reductase inhibitor with lutetium Lu 177 dotatate, showing potential for improved treatment outcomes in patients with progressive GEP-NETs. The results have led to a planned phase 2 randomized trial to assess progression-free survival.
The University of Cincinnati's Center for Clinical & Translational Science & Training has received a seven-year, $37.2 million grant renewal to support its mission in advancing translational science and research. The center will transform into an integrated Clinical and Translational Learning System to accelerate the discovery, dissemi...
This review of research on music- and nature-based strategies for mental health and wellbeing found that these interventions can offer adaptable low-cost, multi-sensory approaches for people of all ages. Studies showed that combined therapeutic use of music and nature facilitates self-expression, improving mood and emotional well-being.
A new study by Texas A&M University Health Science Center reveals how TFE3 oncofusions hijack RNA to build liquid-like hubs that promote cancer growth. The researchers also created a molecular switch to dissolve these hubs, cutting off tumor growth at its source.
A team of scientists analyzed 300,000 years of genetic history of Franklin's bumble bee and found that population bottlenecks and environmental issues such as fire and drought led to its decline. The study suggests that the species' extinction vulnerability arose from historically low effective population size and genetic diversity.
Researchers found that wildflowers are blooming about 17 days sooner than a century ago, while pollinators start flying 11 days earlier. However, some species, like the western bumblebee, are emerging later, which could leave them struggling to find food.
A recent study suggests that unconscious cognitive processes, such as cumulative redundancy bias, can lead people to believe in election fraud. The researchers found that the way vote counts are reported can influence perceptions of candidate strength and even beliefs in voter fraud, regardless of party affiliation.
A new survey conducted by UC Berkeley researchers found that approximately 75% of agricultural workers in Sonoma County have worked during wildfires since 2017. The study also found that half of the farmworkers reported having ailments like headaches or sore throats after working during a wildfire.
A new study found that safety reviews on Airbnb can reduce bookings and lower nightly prices, but the increased transparency can mitigate this effect. The researchers analyzed 4.8 million guest reviews from five major US cities between 2015 and 2019.
Scientists have discovered a family of enzymes produced by Phytophthora infestans that disable plants' early warning system, weakening their defenses before they can respond. Disabling the genes for these enzymes rendered the pathogen incapable of infecting the host.
Protein clumps associated with Parkinson's disease can actively break down ATP, draining brain cells of vital energy. Researchers discovered that these clumps transform into molecular machines when they bind to ATP, highlighting a new mechanism of damage.
Research shows strong Midwest summer storms can puncture the stratosphere, bringing aerosols and burning biomass from western wildfires. This could affect the ozone layer's stability and warm the stratosphere.
A study measuring the impact of a data-driven health strengthening project in Madagascar demonstrates success with a 30% reduction in child deaths. The project provides universal access to basic healthcare, improving outcomes despite challenging conditions.
Mike Leach, the mastermind of the air raid offense, will be recognized posthumously for his exceptional contributions to college football. The American Heart Association's Paul “Bear” Bryant Heart of a Champion Award honors Leach's larger-than-life impact on the game and communities he touched.
A team of scientists from Chile and the US discovered dozens of red cusk-eels embedded in tubeworm bushes at a methane seep. The finding suggests these seeps are not just habitats for obscure creatures but also important for commercially fished species like cusk-eels.
Researchers discovered that folate receptor beta is widely expressed in various pediatric and adolescent solid tumors, making it a promising target for improving tumor surgery accuracy. Pafolacianine, a next-generation dye targeting folate receptors, shows promise as a tumor-agnostic imaging strategy for pediatric cancer surgery.
The ESMO Guidance on the Use of Large Language Models in Clinical Practice (ELCAP) provides a structured set of recommendations for safely adopting AI language models in oncology. The guidance emphasizes the importance of human oversight, transparent tools, and continuously monitored systems to ensure trust in AI-driven cancer care.
A new study found that crayfish with larger but weaker claws swam more slowly due to energetic trade-offs. Removing one or both claws improved swimming performance, highlighting the physical burden of carrying oversized weapons.
An international research team proposed a new sustainable management concept for krill stocks in the Southern Ocean, integrating fishing activities with closely-meshed scientific monitoring. This approach aims to ensure the long-term protection of the ecosystem and align commercial interests with conservation goals.
A recent study published in JAMA Ophthalmology found that corneas from donors with diabetes are just as effective for surgery as those without the disease. The results suggest that the number of corneas available for transplant worldwide could be significantly increased, improving outcomes for patients seeking sight-restoring transplants.
A new digital health program has been found to significantly increase lung cancer screening rates among people at high risk. The study, which tested a direct-to-patient program, showed that 24.5% of participants completed a screening CT scan within 16 weeks, compared to 17% in the usual care group.
Researchers at the University of Galway have discovered that structural stromal cells in bowel cancer can 'switch off' the immune system and how targeting these cells could reactivate natural killer cells to fight cancer. The study's findings have significant implications for immunotherapy treatment.
A pioneering eye device has restored reading vision to people with sight loss, allowing them to read letters, numbers, and words through a prosthetic eye. The PRIMA chip operation involves an implant paired with augmented-reality glasses, enabling patients to regain their independence and confidence.
The Damon Runyon Cancer Research Foundation has named the newest cohort of SPARK Scholars, providing post-baccalaureate scholars with research training, mentors, and networking opportunities. The program's recipients will conduct cancer research in top institutions and present their findings at the annual Damon Runyon Fellows' Retreat.
A direct-to-patient digital health intervention increased lung cancer screening rates compared to enhanced usual care. The study's findings suggest that such interventions could improve lung cancer screening across diverse populations and healthcare settings.
The new textbook explores the environmental consequences of medicine production, use, and disposal, highlighting pharmaceutical residues in ecosystems and resource consumption. It emphasizes the need for multidisciplinary collaboration to develop environmentally sustainable medicinal products and medications.
The acquisition unifies genetics and stem cell research expertise to accelerate discovery and translate science into therapies. Researchers will gain access to advanced platforms, including the NYSCF Global Stem Cell Array, to study disease mechanisms and test treatments.
Researchers from Trinity College Dublin have found a universal thermal performance curve that unifies seemingly different temperature curves for various species. This discovery suggests that species are more constrained than expected in adapting to global climate change, as temperatures rise.
Researchers found that even extreme athletes cannot surpass an average metabolic ceiling of 2.5 times their basal metabolic rate in energy expenditure. The study tracked ultra-runners and cyclists, finding that while they can burn six to seven times their BMR during multi-day races, longer periods see a return to the predicted ceiling.
Researchers mapped greenhouse gas emissions associated with producing meat for cities across the contiguous US, providing city-specific information to reduce environmental impact. The study found that cutting half of beef consumption can result in similar greenhouse gas savings, and transportation emissions are not a major factor.
A new national study published in the Proceedings of the National Academy of Sciences found that public Montessori preschool programs deliver stronger early learning outcomes for children, including elevated reading, memory, and executive function. The study, which tracked nearly 600 children across 24 public Montessori programs nation...
A new technique allows engineers to more precisely place patches on microscopic building blocks, controlling their assembly into designer structures. This stenciling method provides a quantum leap in control over the building blocks' designs, enabling the creation of sophisticated materials from nanoparticles.
The study found a 6.3% increase in participating physicians between 2013-2023, with those in nonmetropolitan counties and full-shortage Health Professional Shortage Area counties more likely to exit the program. This trend is expected to reduce access to care for already underserved communities.
A new mathematical framework, STIV, can predict larger-scale effects like proteins unfolding and crystals forming without costly simulations or experiments. The framework solves a 40-year-old problem in phase-field modeling, allowing for the design of smarter medicines and materials.
Researchers have published a comprehensive review on the latest advances in regulating Bi-based catalysts for photoelectrocatalytic CO2 reduction, providing guidance for high-performance catalyst design. The study aims to promote the development of efficient CO2 reduction technologies with enhanced activity and selectivity.
The study found that using circulating tumor DNA to guide treatment resulted in fewer recurrences, hospitalizations, and treatment side effects among patients who tested negative for ctDNA. Patients with positive results did not see improved outcomes from escalated therapy.
A national poll found that 1 in 10 young children play outdoors as infrequently as once a week, while nearly all engage in screen time daily. Parents are encouraged to create space for active, imaginative, and social play to support healthy development.
Researchers developed a machine learning model that uses MRI scans to predict which patients with mental illnesses will gain weight after diagnosis, and which ones won't. The BMIgap tool has the potential to prevent future weight gain and reduce the risk of metabolic diseases.
A photovoltaic thermo-electro dual module system (PTEDMS) integrates solar energy, electrical resistance heating, electrokinetic transport, and thermal storage to efficiently remove organic pollutants. Machine learning optimizes solar energy allocation, ensuring continuous operation under fluctuating sunlight conditions.
A new study analyzed Estonian BMI data and identified unique genetic traits influencing appetite and body weight. The research found a link between genetic variants in the MC4R and POMC genes and body mass index (BMI), with some individuals tending to have lower or higher BMIs due to these variations.
A recent study found that telehealth medication abortion requests doubled in 18 states following the Dobbs decision, with the majority of requests occurring before 6 weeks of pregnancy. This increase builds upon previous findings indicating a rise in telehealth requests among individuals living far from in-person abortion services.
Rebecca Richards-Kortum has been elected to the National Academy of Medicine for her major contributions to global health. She created low-cost, lifesaving technologies for underserved communities, transforming health systems worldwide through her innovations in cervical cancer diagnostics and neonatal care technologies.