This study analyzed 740 endometrial polyps and found a low but notable risk of malignancy, particularly in postmenopausal patients. The results suggest that routine sampling of the background endometrium during polypectomy is essential for early detection of serous carcinoma.
A new HepaRG human hepatocyte model with enhanced CYP2D6 activity has been developed to predict drug-induced liver injury. The model enables more human-relevant evaluation of drug toxicity mediated by CYP2D6, offering a promising alternative to animal testing.
A new mechanism utilizing interfacial phase equilibrium regulates metal ion migration in CZTSSe photovoltaic cells, reducing deep-level defects and improving crystalline quality. The approach achieves a record-high open-circuit voltage of over 600 mV, overcoming long-standing energy losses.
Wataru Takeda has completely solved the polynomial analogue of the long-standing Brocard–Ramanujan problem, a breakthrough 150 years after its original proposal. The study resolves the problem for polynomials over finite fields and was published in the journal Finite Fields and Their Applications.
Nagoya University researchers have developed an iron-based alternative to expensive chiral ligands in metal-based photocatalysts, achieving a precise radical cation cyclization and the first total asymmetric synthesis of (+)-heitziamide A using blue LED light and abundant iron.
SynapTrack enables faster and more accurate detection of fraudulent activity using blockchains and cryptocurrencies, reducing false positives by a substantial margin. The system has been tested with real-life data from the Bybit hack, tracing hackers with 98% accuracy.
Approximately 40 cancer patients will receive LMP744 for five consecutive days, with biological analyses conducted on brain tissues before and after treatment. If results are favorable, treatment will continue for 12 cycles to evaluate parameters such as progression-free survival and overall survival.
A new study from Nagoya University and Gifu University found that multisensory museum experiences can engage visitors with culturally significant heritage. By incorporating sensory elements like smell and touch, visitors can form personal connections to the artifacts, leading to deeper engagement and conservation efforts.
Crude extracts from Tithonia diversifolia and Solanum torvum exhibit significant antibacterial activity against selected Shigella species. Hexane extract from S. torvum and dichloromethane extract from T. diversifolia inhibit bacterial growth with minimum inhibitory concentration values of 500 and 1,000 µg/mL.
Dr. Qiliang Ding, a trainee researcher, received the inaugural 2026 Rising Scholar Trainee Award for his innovative work on clinical implementation of emerging genomic technologies. His research focuses on data analytics and bioinformatics to advance genomic diagnostics.
KRISS has developed a low-power sensor capable of selectively identifying multiple hazardous gases. The new technology consumes significantly less power than conventional sensors, offering greater cost efficiency while delivering broad applicability.
Researchers have discovered a new species of jellyfish, Malagazzia michelin, found in Japanese waters. The species has distinctive brown spots and a hemispherical umbrella-shaped body.
Research from Washington State University found that women are willing to pay higher prices for wines made by female winemakers, particularly those featuring feminine gender cues. The study suggests that promoting women's ownership in wineries can increase sales among the largest group of U.S. wine consumers, who happen to be women.
Researchers studied Norwegians with reported chronic health problems linked to tick bites, finding no objective evidence of persistent infections. The study suggests that physical activity and labour force participation may be more related to symptoms than tick exposure.
Research reveals that liquid crystal monomers from household electronics accumulate in the brains of endangered dolphins and porpoises. The chemicals have been linked to altered gene activity and potentially negative impacts on marine mammals.
Astronomers have captured unprecedented detail of cosmic gas in the Milky Way's Central Molecular Zone, revealing intricate chemistry and complex star-forming processes. The dataset provides a unique view of the raw material from which stars form, shedding light on galaxy evolution and the birth of massive stars.
The study found that opioids provide only small, time-limited pain relief for certain pain conditions, such as stomach pain and dental surgery. Regular use of opioids comes with a risk of harm, including dependence and overdose.
Pyrochlore oxides represent a promising next-generation approach to efficient energy storage, offering high-energy density, thermal stability, and low dielectric loss. Their potential applications include multilayer ceramic capacitors, power conditioning circuits, and miniaturized capacitors for aerospace electronics.
Immune cells have been found to selectively extract nuclear DNA from dying cells, a regulated cellular function that challenges traditional views of the nucleus. This discovery, known as nucleocytosis, may hold implications for understanding autoimmune diseases, infections, and cancer, as well as informing drug development strategies.
Researchers have developed a printable enzyme ink that simplifies the mass production of enzymatic biofuel cells, paving the way for self-powered wearable sensors. The ink enables the creation of high-performance electrodes with minimal decay, suitable for real-world monitoring applications.
Researchers at IMDEA Networks Institute discovered that tire pressure sensors in modern cars can be used to track vehicles and infer movement patterns. The study highlights the need for stronger security measures in future vehicle sensor systems.
A global analysis of over 40 years of scientific research reveals that vessel traffic affects animal behavior, communication, and stress physiology in marine megafauna. The study identifies stronger responses from species like sea turtles and weaker impacts on others, such as large fishes and sharks.
A new study reveals that air-conditioning use will more than double by 2050, causing up to 8.5 GtCO₂‑eq per year in the worst-case scenario. This is equivalent to around 74–183 billion transatlantic return flights and adds 0.03°C to 0.07°C of global warming.
Research found that people living in deprived areas have less diverse gut microbiomes, leading to increased inflammation and poorer metabolic health. The study identified 12 bacterial species associated with deprivation, including those negatively linked to anxiety and diabetes.
A new study reveals that ocean warming is driving a nearly 20% annual decline in fish biomass, with extreme marine heatwaves sometimes masking this trend. The research highlights the importance of international cooperation and long-term planning in fisheries management to address the ongoing rise in temperature.
A ketogenic diet reduced high blood sugar and improved aerobic capacity in mice with hyperglycemia. The diet caused remodeling of their muscles, making them more oxidative and reactive to aerobic exercise. Researchers believe that combining the keto diet with exercise may be key to achieving optimal health benefits.
A new American Heart Association scientific statement projects that nearly 6 in 10 US women will have some type of cardiovascular disease by 2050, driven by rising rates in high blood pressure and other health factors. The economic burden is expected to be at least $200 billion annually.
A new study by Manchester researchers argues that directional terms like 'upcycling' and 'downcycling' can skew perceptions of plastic sustainability. The study suggests that a more nuanced approach is needed to evaluate the environmental impact of recycling technologies.
A new study from Chalmers University finds that local water supply is critical to the success of Europe's hydrogen initiative, with some regions facing severe water shortages if production is not planned carefully. The research suggests that areas like Sweden's Sörmland and Roslagen could be hard-pressed even without hydrogen production.
A new blood test score, MetALD-ALD Prediction Index (MAPI), has been developed to identify when fatty liver disease is driven by excessive alcohol use. The tool uses five standard lab values and can estimate whether a person with fatty liver disease may have alcohol-related liver injury.
Researchers identified nine piRNAs linked to longevity, which could be detected through simple blood tests. The study suggests that these molecules may help predict survival and guide therapeutic targets for older adults.
The European Centre for Medium-Range Weather Forecasts (ECMWF) is launching its 2026 climate and weather data challenges to improve rapid decision-making during wildfires, explore flood forecast data from 10,000 stations globally, and detect implausible behavior in machine learning. The deadline for applications is April 9, 2026.
A study published in European Heart Journal found that nearly half of hospitalised heart failure patients are readmitted within a year, with the risk of death also remaining high. Patients with severely reduced heart function face the highest risk, highlighting the need for careful follow-up and tailored care.
A new study from Duke University Medical Center suggests that a simple blood test can accurately predict short-term survival in older adults by detecting specific piRNA molecules. Lower levels of these molecules are linked to longer survival, echoing patterns seen in simple organisms where reducing them can extend lifespan.
The Blavatnik Awards recognize exceptional early-career achievements in Life Sciences, Chemical Sciences, and Physical Sciences & Engineering. The 2026 Laureates are Maxie M. Roessler, Thi Hoang Duong Nguyen, and Paola Pinilla.
A study found that Targeted Regulation of Abortion Providers (TRAP) laws significantly reduced the supply of obstetricians and gynecologists, particularly older and newly trained doctors. This led to a decline in more than 2 obstetrician-gynecologists per 100,000 females aged 15–44 years.
A study found that international guidelines for preterm delivery are often not followed, leading to varying levels of exposure to life-saving medications. In high-income countries, there were significant discrepancies in the use of these treatments.
New research reveals that skeletal muscle retains a 'molecular memory' of repeated disuse, which differs between young and old muscles. Younger muscles show resilience, while older muscles become increasingly susceptible to atrophy. The study provides insights into how muscle responds to inactivity and its potential for recovery.
A global analysis of two antenatal treatments reveals significant international variation in implementation, with higher-income countries showing better uptake. The study highlights the need for further research to understand the reasons behind these disparities and improve global equity in essential antenatal treatments.
A major new study found that high-risk patients, who tend to be older and live with several long-term health conditions, have poor outcomes after surgery. The study highlights the need for greater investment in specialist perioperative services to focus on the care of older, high-risk patients before, during and after surgery.
Researchers found caterpillars mimic ant signals using precise rhythmic beats to gain acceptance, feeding, and protection. The most ant-dependent species produce regular, complex rhythms similar to those used by ants.
A solitary bottlenose dolphin in the Venetian Lagoon is monitored by researchers who assess its remarkable adaptation to urban surroundings. The team highlights the need for human behavior management to ensure the dolphin's welfare, rather than focusing on wildlife protection measures.
A new Tulane University study reveals that SARS-CoV-2 infection causes persistent brain inflammation and small blood vessel injury, even after the virus is no longer detectable. This finding helps explain why long COVID often includes neurological symptoms such as brain fog and fatigue.
A recent study reveals that creators who disclose using AI face negative judgments from others, despite their reputation. This gap between technological capability and social perception highlights the need for creators to manage perceptions surrounding how their work was created.
A new Flinders University study reveals that fear of punishment and lack of trust in management are major barriers to tackling alcohol and drug risks at work. SBIRT, a health-based approach, is proposed as a solution, but its effectiveness depends on trust and confidentiality.
The nanozymes hypothesis suggests that natural mineral nanozymes played a crucial role in the origin of life on Earth, catalyzing the generation of prehistoric small life molecules from nonliving matter. These nanozymes enabled informationization of energy into molecules necessary for living systems.
A Korean research team developed a technology that resolves the most critical challenge of lithium-metal batteries, interfacial instability, by creating an intelligent protective layer. This allows lithium ions to move stably along the electrode surface, suppressing dendrite growth and extending battery lifespan.
Early land plants began reshaping Earth's surface environments approximately 455 million years ago, boosting organic matter production on land. This increased terrestrial photosynthesis led to elevated organic carbon-to-phosphorus ratios in marine sediments, indicating a significant impact on the Earth system.
Researchers at Flinders University have developed a new method to remove toxic PFAS chemicals from water using nano-sized molecular cages. The study successfully captures short-chain variants of the pollutants, which are notoriously difficult to isolate.
Chinese scientists have developed a dual-side electrical refinement strategy for large-area TOPCon solar cells, achieving an open-circuit voltage of 744.6 mV and a fill factor of 85.57%. The breakthrough sets a new record for industrial-scale solar cells, narrowing the gap between mass-production efficiency and theoretical limit.
Recent advances in biochar-polymer composites suggest the use of renewable materials for additive manufacturing. Biochar enhances mechanical and thermal properties, reducing environmental impact while improving material performance.
Researchers developed a machine learning-guided strategy to design advanced biochar materials that remove phosphorus efficiently while lowering treatment costs. The study provides a practical pathway for restoring eutrophic waters at large scale.
Researchers developed a nickel-enriched biochar from marine microalgae that can detect hydrogen peroxide at low concentrations, with fast response times. The sensor's stability and sensitivity are improved by the uniform distribution of catalytic sites.
A recent study has confirmed that wild African chimpanzees consume significant quantities of alcohol, with 17 out of 20 urine samples containing ethyl glucuronide, a metabolic byproduct of ethanol. The chimps' diet likely consists of fermented fruits, which provide around 14 grams of ethanol per day.
Lifespan-extending treatments and dietary restriction have increased variance in age-at-death in vertebrates, failing to 'square the survival curve'. The findings highlight that current interventions do not equally benefit all individuals, leading to a biological lottery.
A new study based on extensive data from Swedish school surveys found that changes in average cannabis use among adolescents are reflected across the entire group. The distribution of cannabis use has remained highly stable over time, with increases or decreases occurring in parallel across all user groups.
Researchers propose a new electrolyte additive strategy to solve three core challenges in zinc-iodine batteries: sluggish iodine reaction kinetics, polyiodide shuttle effect, and zinc dendrite growth. The study achieved ultra-long cycle stability and excellent performance with minimal capacity decay.
Research published in the journal Gut found that pre-pregnancy parental overweight and obesity are independently associated with increased odds of developing metabolic dysfunction associated steatotic liver disease (MASLD) in children by age 24. Cumulative excess weight in childhood significantly influences this risk, with children who...
The Barshop Institute will conduct the VITAL-H trial, evaluating the repurposing of FDA-approved medications to delay age-related health decline in generally healthy middle-aged adults. The trial aims to preserve everyday abilities during a critical window of midlife aging.
A new volume of comics studies argues that comics from the Global South need to be read on their own cultural terms, highlighting their use as a tool for resistance, identity assertion, and social change. The book showcases diverse case studies from Latin America, Africa, Asia, and beyond.