A Duke-NUS study found that mandatory Nutri-Grade front-of-pack labels on beverages redirected household consumers to healthier drinks and encouraged manufacturers to reformulate products with less sugar. The study resulted in an 18% reduction in sugary drink consumption and a 44% decrease in purchases of unhealthy drinks.
Generative AI is transforming pharmaceutical RÝ into a highly efficient, end-to-end new era. Insilico Medicine has accumulated extensive experience in AI-driven drug discovery, sharing breakthroughs and latest advancements in molecular design, multi-target synergy, and clinical translation success rates.
Scientists from the University of Osaka have identified a previously unknown molecular mechanism linking mitochondrial morphology to innate immune activation. Abnormally long mitochondria can trigger the release of mitochondrial RNA into the cytosol, activating RNA-sensing proteins and leading to anti-tumor immunity.
A new device inspired by fish's lateral line senses the pulse of lab-grown heart tissue, enabling real-time monitoring of hundreds of tests. This breakthrough could revolutionize drug screening and personalized medicine with more accurate human tissue simulations.
Researchers identified a hierarchically organized nerve network in mouse aorta that drives blood pressure rise after cold exposure. Local ablation of sympathetic nerves in aPVAT prevents cold-induced hypertension, underscoring the specificity of aPVAT.
A large longitudinal cohort study of 64,371 men aged 50 and above found no statistically significant association between low handgrip strength and prostate cancer risk. The study suggests that grip strength is unlikely to be a reliable tool for early detection or predicting disease progression.
A new genome assembly provides insights into the genetic system behind oregano's valuable oil, revealing a JA-inducible transcription factor that directly regulates EO biosynthesis. The study identifies OvbHLH13 as a molecular target for improving EO yield and quality in Greek oregano.
A new SPR holographic microscope has been developed with high sensitivity, label-free, non-invasive, and real-time measurement capabilities. It achieves ultrahigh RI resolution of 2.58 × 10⁻⁷ RIU and sub-nanometer thickness profiling resolution of 0.6 nm for atomic layer materials.
Researchers have developed new catalytic routes for ammonia synthesis under mild conditions, including one-step thermal catalysis, electrocatalysis, and photocatalysis. These emerging strategies aim to reduce energy consumption and emissions, offering promising alternatives to the Haber-Bosch process.
The UJI Institute of Advanced Materials has developed a new methodology for producing advanced catalytic materials with improved catalytic activity and efficiency. The process uses transition metals, reducing the need for expensive noble metals and generating high-purity hydrogen.
Researchers analyzed tar-rich and tar-inclusive coals using thermogravimetry and differential scanning calorimetry. Tar-rich coal exhibited lower characteristic temperatures and activation energies, making it more prone to ignition but also suitable for in-situ thermal decomposition mining.
Researchers developed AdapGNN to improve graph neural network explainability in molecular property prediction. The framework achieves better predictive accuracy and explainability, especially for molecule energy prediction.
Endothelial CPT2 loss impairs long-chain fatty acid oxidation, activating an EndoMT-like program that promotes renal injury and fibrotic remodeling. Acetate supplementation partially suppresses this phenotype.
KAIST researchers have discovered a new way cancer 'hijacks' the blueprint for blood vessel development to fuel its growth. By reactivating a pre-existing gene regulatory program, tumors can drive angiogenesis without evolving entirely new mechanisms.
An international team of scientists has rediscovered a set of gigantic Megalodon vertebrae in Denmark, shedding new light on the prehistoric shark's biology and lifestyle. The discovery confirms the maximum vertebral diameter of 23 cm reported in literature and represents the largest fish vertebrae ever recorded.
A new scanning technique has shown that lithium levels in the brain and blood are closely matched across the day, regardless of dosing regimen. This finding could lead to more personalized treatment options for patients with bipolar disorder.
A new study led by King's College London finds that human-driven climate change has intensified the retreat of Pine Island Glacier, one of the single biggest contributors to global sea level rise. The glacier retreated by around 18-20% since the 1940s, adding several kilometers to its landward withdrawal.
A bio-inspired robotic bird is helping researchers unravel the mysteries behind kestrels' exceptional hovering capabilities. By mimicking key movements, the team discovered unique techniques that could improve manoeuvrability of small aircraft and enhance their ability to cope with turbulence.
A 57-year-old MDS patient presented with CD34+ micromegakaryocytes and giant platelets in peripheral blood, raising concerns for acute leukemia misdiagnosis. Follow-up studies showed persistent iron-deficiency anemia and easy fatigability, while laboratory results revealed pancytopenia.