A study found that rats fed a high-fat diet exhibited 12% less body weight gain after ingestion of 10 μl of an ionic liquid composed of choline and geranate (CAGE) once a day for 30 days, compared with rats that were not treated with the ionic liquid; CAGE also reduced the amount of food consumed, intestinal fat uptake, and docosahexaenoic acid absorption by 60-70%, suggesting the potential of CAGE for controlling body weight.
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Article #19-14426: "Oral ionic liquid for the treatment of dietinduced obesity," by Md Nurunnabi et al .
MEDIA CONTACT: Samir Mitragotri, Harvard University, Cambridge, MA; email: mitragotri@seas.harvard.edu
Proceedings of the National Academy of Sciences