In an accompanying commentary, Mark Gladwin from the National Institutes of Health discusses the broad biology of the nitrite anion and its potential utility in the treatment of gastric ulcers, or conditions associated with scavenging of nitric oxide, such as sickle cell anemia. Gladwin suggests "At the very least, perhaps we should avoid mouthwash and feel less guilty about eating hot dogs at the ball park."
TITLE: Nitrite in saliva increases gastric mucosal blood flow and mucus thickness
AUTHOR CONTACT:
Jon Lundberg
Karolinska Institutet, Stockholm, Sweden.
Phone: 46-8-728-7952
Fax: 46-8-332-278
E-mail: jon.lundberg@fyfa.ki.se
View the PDF of this article at: http://www.jci.org/cgi/content/full/113/1/106
ACCOMPANYING COMMENTARY: Haldane, hot dogs, halitosis, and hypoxic vasodilation: the emerging biology of the nitrite anion
AUTHOR CONTACT:
Mark T. Gladwin
National Institutes of Health, Bethesda, Maryland, USA.
Phone: 301-435-2310
Fax: 301-402-1213
E-mail: mgladwin@nih.gov
Journal of Clinical Investigation