Articles tagged with Blood Flow
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
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Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers tracked 120 older veterans taking gabapentinoids and loop diuretics, finding that only 4 doctors correctly identified the gabapentinoids as the cause of leg swelling. The study highlights the dangers of 'prescribing cascades' and emphasizes the need for regular monitoring and alternative treatment options.
Researchers discovered how newly created neurons rely on blood flow to migrate through the brain. The study found that blood vessels act as physical 'scaffolds' and that blood flow influences migration speed, with higher speeds seen in regions with abundant blood flow.
Researchers have developed novel nanomaterials to combat myocardial ischemia-reperfusion injury, demonstrating significant cardioprotective effects in preclinical models. These nanoplatforms improve drug enrichment efficiency and reduce systemic toxicity, showing considerable clinical translation prospects.
Researchers from USC Neurorestoration Center and Caltech created a simple, noninvasive device using laser technology to measure brain blood flow. The tool has already been tested with humans in small proof of concept studies demonstrating its utility for assessing stroke risk and detecting brain injury.
A new dual-imaging system simultaneously maps retinal structure and capillary oxygen levels in live mice, allowing researchers to study vision-threatening diseases like glaucoma and diabetic retinopathy. This non-invasive approach offers a powerful tool for elucidating local capillary values and tracking changes in retinal oxygenation.
UCLA researchers have identified two key proteins, HuR and CEACAM1, that act as protective switches to prevent damage in damaged livers. By boosting this protection, organs deemed unsuitable for transplantation could be made suitable for use.
A new study using two-photon microscopy shows that brief interruptions in brain capillary flow can cause rapid drops in oxygen levels, potentially leading to tissue damage. The research found that even minor stalls can lead to significant hypoxia, highlighting the importance of uninterrupted blood flow to the brain.
A study found that prolonged sitting decreases cutaneous vasodilatory function under both constant and alternating temperature conditions. Alternating exposure to cooling and heating did not significantly suppress these changes.
Researchers at Harvard Medical School have discovered a cellular signaling highway in the brain's blood vessels that enables blood flow to be directed on demand. The findings could improve understanding of neurodegenerative diseases and enhance interpretation of functional MRI scans.
Researchers developed a low-radiation dose imaging protocol and a deep learning model to generate vital blood flow maps for assessing stroke patients. The innovation slashes radiation exposure by over 80% compared to current methods, making stroke diagnosis safer and more accessible.
A new computational method combines 4D flow MRI, CFD, and data assimilation to estimate blood flow in brain aneurysms with greater accuracy and efficiency. The approach focuses on the aneurysm region, reducing computational cost while improving flow estimation.
Researchers used a new fMRI analysis method to measure cerebrovascular reactivity in 53 adults aged 51-83. They found an unexpected improvement in brain health in postmenopausal female participants, primarily in areas related to movement and memory.
Researchers are developing a cutting-edge blood test that can accurately track clot formation and breakdown. This innovative approach has the potential to improve patient treatment and reduce complications associated with current treatments.
Researchers discovered a promising new approach to treating hemorrhagic shock, which tripled survival rates and maintained healthy organ function. Activating Protein Kinase C epsilon (PKC-ε) significantly improved early survival rates and physiological stability following severe hemorrhage.
Recent high-quality deepfake videos can feature realistic heartbeats and minute changes in face color, making them challenging to detect. Researchers found that even small variations in skin tone and facial motion can replicate the original pulse in deepfakes.
Researchers have discovered a new pathway that may lead to a treatment for high blood pressure and aortic aneurysms. By targeting the protein DUSP-3, the team was able to block the development of aortic aneurysms and reduce hypertension in mice.
Researchers at Aarhus University have developed a new understanding of how brain blood vessels react after a stroke. By mapping the molecular changes, they hope to find targeted therapies to improve patient outcomes.
A POSTECH research team developed a photoacoustic computed tomography (PACT) system that non-invasively monitors cerebrovascular changes in small animals with early stages of an ischemic stroke. The technology also measures oxygen saturation in blood vessels, allowing precise tracking of vascular recovery after stroke.
A recent study found an association between chronic stress and an increased risk of stroke in younger women, but not men. The study, which looked at 426 participants aged 18-49 who experienced an ischemic stroke with no known cause, found that moderate stress levels were associated with a 78% increased risk of stroke.
Researchers at UCSF have discovered that human lung tissue contains hematopoietic stem cells (HSCs) capable of producing red blood cells, platelets, and immune cells. The finding suggests the lungs could be a potent source for life-saving stem cell transplants, particularly for patients with leukemia.
Kennesaw State researcher Chen Zhao has earned the 2025 American Heart Association Institutional Research Enhancement Award for his innovative study on non-invasive blood flow prediction in cardiovascular disease diagnosis. His technology uses coronary computed tomography angiography (CCTA) scans to measure Fractional Flow Reserve (FFR...
A study published in Mayo Clinic Proceedings found that patients who can exercise during cardiac stress testing have a lower mortality rate than those who cannot. The researchers discovered that assessing a patient's ability to exercise during testing provides a stronger distinction between high- and low-risk patients.
Researchers analyzed data from three trials and found nerinetide provided a clinically significant benefit to patients. The findings suggest that treating early, fast, and administering the drug can lead to improved patient outcomes.
A new method allows for accurate measurement of blood-brain barrier permeability, revealing that many CNS drugs penetrate the barrier rapidly. The study found that plasma proteins play a crucial role in maintaining brain delivery of lipophilic agents.
A new study suggests that delivering tenecteplase directly into a large brain artery after removing a blood clot can improve stroke survivors' function 90 days later. The treatment, which was tested in 127 patients, showed promising results compared to standard medical care.
UCalgary researchers confirm that endovascular thrombectomy (EVT) is not effective for patients with blockages in medium-sized blood vessels. The ESCAPE-MeVO clinical trial found no improvement in outcomes for these patients compared to standard care. EVT was previously shown to improve patient outcomes after large-vessel strokes.
A recent study investigated hybrid diffuse optics to monitor changes in blood flow and oxygen levels noninvasively. The technology provided detailed insights into how oxygen is delivered and utilized in the body, suggesting improved outcomes for critically ill patients undergoing red blood cell transfusions.
A new nanotechnology-based drug delivery system has been developed to save patients from repeated surgeries. The approach, called Pericelle, uses a paste of nanoparticles containing hydrogel on transplanted veins to prevent blockages, which can lead to repeated surgeries in heart and dialysis patients.
Persistent microvascular over-dilation may cause muscle hypoxia, worsening chronic limb-threatening ischemia outcomes. Research suggests this phenomenon could be used to screen and treat patients with the disease.
Researchers discovered that norepinephrine triggers blood vessel constriction to propel cerebrospinal fluid through the brain, clearing out waste. The findings suggest that sleep aids may disrupt this process, potentially affecting long-term cognitive health.
Researchers used STOC-T to visualize retinal microcirculation in real-time, providing insights into the mechanisms of retinal function. The study offers a groundbreaking opportunity for precise monitoring of hemodynamic changes in the retina, enabling early detection and treatment of diseases such as Alzheimer's and Parkinson's.
Researchers have developed a non-invasive strategy that assesses blood flow through skeletal muscle to detect early signs of sepsis. The technique, combining hyperspectral near-infrared spectroscopy and diffuse correlation spectroscopy, was tested in rodents and detected sepsis before vital organs were affected.
Ken Perry, a UTA senior, has been recognized for his research on the connection between high-fat meals and cardiovascular health. He won two awards from the American Physiological Society for his work analyzing data collected from previous studies, which showed a correlation between high-fat consumption and changes in brain blood flow.
Researchers found a novel link between aortic stenosis and insulin resistance, with certain biomarkers increasing the risk of the disease. The study's findings suggest that managing metabolic health could be a new approach to reduce the risk of AS and improve cardiovascular health in aging populations.
Researchers identified acute effects of cigarette and e-cigarette smoking on vascular function, including decreased blood flow velocity and venous oxygen saturation. The study found that vaping with and without nicotine led to significant changes in vascular function, highlighting the potential harm of vaping even without nicotine.
Researchers from Salk Institute found that specific dietary fats are incorporated into sphingolipids to drive the development of atherosclerotic cardiovascular disease. The team discovered that trans fats are preferentially metabolized by an enzyme, leading to increased lipoprotein secretion and plaque formation.
Researchers found that a high-flavanol cocoa drink can protect the body's vasculature against stress even after eating high-fat food. Flavanols in green tea and other foods also showed benefits for cardiovascular health.
Researchers found that ablation reduced ICD shocks for ventricular tachycardia and episodes of VT not detected by the ICD. This minimally invasive procedure destroys abnormal heart tissue causing VT, offering a better alternative to long-term medication side effects.
A new system combining high-speed video and an AI algorithm can detect high blood pressure and Type 1 or Type 2 diabetes from subtle changes in blood flow, potentially leading to early detection and treatment. The technology is still in its preliminary stages but holds promise for non-invasive monitoring of health at home.
A new hourglass-shaped stent could improve blood flow and alleviate severe chest pain in people with microvascular disease. The study found that 76% of participants experienced improvement in their daily activities, including walking and climbing stairs without pain.
Scientists from Kaunas University of Technology and Lithuanian University of Health Sciences developed a non-invasive ultrasonic foot stimulation device to improve blood circulation in the lower limbs. The device uses low-frequency ultrasound to stimulate blood flow and regulate thrombogenesis, immune response, and inflammatory processes.
The world's first combined face and whole-eye transplantation successfully used personalized surgical cutting guides and a novel 'shortcut' to maintain blood flow. Innovative techniques ensured optimal blood flow to the retina, safeguarding the viability of the transplanted eye during the procedure.
Researchers at the University of Leeds have found that bile production is affected by blood flow in the portal vein, which can contribute to high cholesterol levels and fatty liver disease. This breakthrough provides an opportunity for the development of new treatments for cardiovascular disease.
Researchers used fluorescein angiography to visualize neural blood flow in rats and rabbits with chronic nerve compression neuropathy, correlating findings with electrodiagnostic testing. The study showed promising results for the method's potential to improve diagnosis and treatment outcomes in carpal tunnel surgery.
Researchers identify modifiable determinants of cerebral blood flow (CBF) and arterial transit time (ATT) in older adults. A higher BMI was associated with lower CBF and longer ATT, while cardiorespiratory fitness linked to longer ATT in specific brain regions.
A team of researchers from USC and Caltech developed a new noninvasive tool to measure brain blood pressure, assessing stroke risk through changes in blood flow and volume during a stress test. The affordable, portable device has the potential to transform stroke care by providing more reliable data than existing questionnaires.
A team of engineers and scientists from Caltech has developed a headset-based device that can noninvasively assess a patient's stroke risk by monitoring changes in blood flow and volume. The device uses speckle contrast optical spectroscopy to differentiate between individuals at low and high risk of stroke.
A new wearable laser device can non-invasively monitor changes in brain blood flow and volume, offering a simple way to assess stroke risk. The device uses speckle contrast optical spectroscopy to detect early physiological signs of increased stroke risk.
A study finds that cardiometabolic indicators like metabolic syndrome and diabetes impair coronary microvascular function, increasing cardiovascular risk. The presence of subclinical atherosclerosis also contributes to altered microvessel function.
A new study by University of Oklahoma researchers identifies key measurements of brain blood flow and ability to compensate as better predictors of mild cognitive impairment than traditional risk factors. The findings provide hope for preventing or treating memory problems early before they progress to dementia.
A team of UBC Okanagan researchers has created a new mechanical heart valve that combines the strengths of both mechanical and tissue replacement technologies, offering improved performance and durability.
The world's first combined whole eye and face transplant has demonstrated allograft survival, including rejection-free graft survival. The transplanted eye has maintained normal pressure, good blood flow, and some remaining structure and functions in the retina. Researchers are now focused on understanding how to restore sight.
A recent study from Waseda University found that short-duration, light-intensity exercises significantly increase oxy-Hb levels in the prefrontal cortex of children, indicating improved cerebral blood flow. This breakthrough suggests potential benefits for children's executive functions and brain development.
Researchers developed an air-powered computer that sets off alarms when certain medical devices fail, preventing blood clots and strokes. The device uses air to issue warnings, reducing costs and improving safety in healthcare settings.
A new mathematical method, validated with experimental animal data, provides fast, reliable, and minimally invasive way of determining how to treat critical blood pressure changes. The method accurately tracks cardiac output and systemic resistance, mirroring estimates from more invasive catheters in some cases.
A recent study at the University of Missouri discovered that oxytocin and corticotropin-releasing hormone cause the brainstem to become overactive, leading to hypertension. This finding can help develop targeted drugs to reduce high blood pressure in sleep apnea patients.
A study published in Circulation found that adults aged 50-54 with severely narrowed leg arteries had a higher risk of amputation after emergency surgery than those aged 80-84. This contradicts the traditional belief that older people are at increased risk.
A novel, star-shaped polymer has been developed as a low-volume resuscitant for prehospital treatment of severe hemorrhagic shock. The solution can refill blood vessels without disrupting coagulation, offering an improvement over existing colloidal resuscitants.
A study of over 4,500 healthy adults aged 60 and older found that nearly 28% had some form of heart valve disease, with age being the main risk factor. The majority of cases were mild, but the study highlights the need for more research into screening methods to identify and manage the disease in the elderly population.
Researchers found that hospitals that implemented standardized protocols from the American Heart Association and American Stroke Association saw significant reductions in stroke treatment times. The protocols, which include specific limits on time between symptom onset and hospital arrival, helped medical teams respond more quickly to ...