Articles tagged with Blood Flow
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Researchers find that a repurposed drug, crizanlizumab, stabilizes vision in patients with retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) after two years of treatment. The study suggests that this may give patients additional years to read, drive, and enjoy activities.
A study by NIH-funded researchers visualizes the full network of blood vessels across the cortex of awake mice, revealing that blood vessels rhythmically expand and contract leading to 'waves' washing across the surface of the brain. The function of these waves remains a mystery.
Researchers found that the angle at which pulmonary veins reach the left atrial appendage affects blood flow and thrombus formation. The study used a sample of 130 patients to investigate the relationship between pulmonary vein morphology and thrombi risk in atrial fibrillation patients.
Researchers developed a wearable ultrasound patch that provides three-dimensional data on cerebral blood flow, addressing clinical standard limitations. The device offers hands-free, continuous monitoring and was tested on healthy volunteers with accurate results, paving the way for potential use in patients with neurological conditions.
A new study found that very early blood pressure lowering treatment can improve outcomes for patients with intracerebral hemorrhage, but worsen outcomes for those with ischemic stroke. Rapid diagnosis of the type of stroke is crucial in harnessing the benefits of this treatment.
Researchers discovered that IL-6 signaling in CD4-positive T cells promotes pulmonary hypertension development and progression. Treating mice with IL-6 inhibitors improved symptoms and decreased damage to the lungs and heart.
A new study found that brief anger episodes can negatively impact blood vessel function, leading to increased risk of heart disease and stroke. The researchers investigated the effects of anger, sadness, and anxiety on blood vessel function and found that evoking an angered state led to blood vessel dysfunction.
Randles developed computational tools to harness supercomputers, creating highly precise simulations of biophysical processes. Her work has direct impacts on patient care, including simulations of 700,000 heartbeats and cancer cells moving through the body.
Researchers have developed a pressure-alternating shoe insole that provides periods of rest to the soft tissues, thereby reducing the risk of diabetic foot ulcers. This innovative technology aims to mitigate the risk of complications from poor circulation and foot sores.
A new study found that a non-invasive imaging test can help identify patients with coronary artery blockage or narrowing who need a revascularization procedure. The test, called CT-FFR, uses CTA images and AI algorithms to model coronary blood flow, reducing the need for invasive procedures.
Researchers found that revascularization treatment significantly improves the quality of life for patients with chronic limb-threatening ischemia, a severe form of peripheral artery disease. The study revealed diminished quality of life among these patients, but revascularization restored sufficient blood flow and improved wellbeing.
Researchers have discovered that neurochemicals influence neural activity, blood flow, and fMRI measurements. The study found that certain neurochemicals can cause constrictions in blood vessels, leading to negative fMRI signals.
Bruno Scheller developed a procedure using drug-coated balloons to treat coronary and peripheral artery disease, improving patients' quality of life. The technique has been widely recognized and effective, with countless patients spared further pain and surgery.
Researchers developed a wearable device for non-invasive monitoring of hemodynamic indicators like heart rate, blood pressure, and oxygen saturation. The photoacoustic imaging watch offers valuable insights into disease diagnosis and treatment.
Researchers at the University of Virginia Health System are developing a technique to 'paint' tiny nanoparticles on transplanted veins to prevent blockages, potentially sparing patients from repeated surgeries. This approach could significantly reduce the number of vascular reconstructions performed annually in the US.
Scientists have developed fUSI technology that enables clinicians to see and map the spinal cord's response to treatments in real-time. This innovation offers improved monitoring of blood flow changes, potentially increasing treatment success rates and optimizing pain relief for patients.
Researchers at the University of Manchester have developed new methods to simulate blood flow, enabling faster and more accurate modeling of vascular diseases. These advancements have the potential to transform medical treatment and device innovation, providing real-time insights during surgical procedures and improving patient outcomes.
Researchers developed a test to predict which heart attack patients are likely to experience dysfunction after receiving mechanical pumps. The test measures pulmonary vascular compliance and its adaptability, helping doctors prevent right ventricle failure.
Researchers found that positioning stroke patients with large vessel ischemic strokes at 0-degrees resulted in significant improvements in neurological function compared to those with 30-degree head positioning. This approach optimized blood flow through the narrowed artery and improved collateral arteries, leading to better outcomes.
A study by Amsterdam UMC shows that Doppler ultrasound can detect placenta problems in small babies, identifying those at higher risk of oxygen deficiency and health issues. The measurement is added to the care plan for these undersized babies, allowing for better detection and monitoring of potential problems.
Researchers at Fralin Biomedical Research Institute and Carilion Clinic found that preserving leg vein grafts in heparinized arterial blood, rather than saline, improves their health and viability. This discovery could lead to better outcomes for patients undergoing coronary artery bypass graft procedures.
Experts recommend increasing the use of intravascular ultrasound (IVUS) in lower extremity revascularization procedures to optimize outcomes and reduce complications. The technique provides detailed information about vessel walls, plaque composition, and blood flow characteristics, enabling more accurate diagnosis and treatment planning.
Researchers used OCTA to visualize retinal blood vessel changes in migraine patients during and between attacks. Blood flow decreases were found, with asymmetrical flow correlated to headache pain side.
Researchers developed a physics-based metric to predict aortic aneurysm development, measuring 'fluttering' in blood vessels. The 'flutter instability parameter' forecasted abnormal growth three years prior to occurrence with 98% accuracy.
Researchers used NIRS to track oxygenated hemoglobin levels in infant brains responding to gentle touch. They found similar response times across age groups, but varying signal amplitudes that may be linked to changes in blood flow and erythropoietin production.
Eating fatty foods during stressful periods can reduce brain oxygenation and cause poorer vascular function in adults. Consuming low-fat food and drinks may help mitigate this effect.
Researchers at Temple University Health System report that the BASHIR Endovascular Catheter reduces blockages in lung arteries and correlates with improved right ventricle function, suggesting better survival outcomes. The catheter also shows significantly lower bleeding rates compared to other devices.
Biomedical engineers at Duke University created a new 'digital twins' framework using smartwatch data to capture personalized arterial forces over 700,000 heartbeats. This approach reduces the computational load by simulating tasks in parallel, enabling real-time tracking of cardiovascular disease progression and risk assessment.
A new study highlights how perimenopausal women's periods may become unpredictable, heavy, and cause worse premenstrual symptoms. The research suggests that improved education and support are needed to manage these changes, including extra support in the workplace, emotional support from loved ones, and access to support groups.
Multimodal neuromonitoring (MNM) tracks blood flow, pressure, oxygen and glucose levels in the brain to inform treatment decisions. MNM has improved clinical outcomes for patients with severe traumatic brain injuries at the University of Cincinnati.
Researchers are conducting a four-year study to investigate the effectiveness of acupuncture in reducing stable angina-related chest pain. The study will enroll 112 participants and compare acupuncture treatment to watching TED Talk videos for symptom relief.
Scientists have discovered a genetic pathway between the heart and brain tied to fainting, suggesting that the heart sends signals back to the brain that can change its function. The study found that vagal sensory neurons play a key role in fainting, with their activation leading to rapid pupil dilation, suppressed heart-rate and breat...
A study published in Annals of Neurology found that receiving clot-busting drug treatment in a mobile stroke unit (MSU) increases the likelihood of averting strokes and complete recovery compared to standard hospital emergency care. Patients treated by an MSU had faster treatment times, with nearly one-third recovering within 24 hours.
A new technique to control severe bleeding in injured patients has been found to increase the risk of death. The REBOA treatment was tested in a clinical trial involving 90 adult trauma patients, but it did not show the expected benefits.
A team of researchers discovered two genetic genes that predispose people to Raynaud's phenomenon: ADRA2A and IRX1. These variations cause small blood vessels to contract in response to stress or cold, leading to vasospasms and limited blood flow. The study could lead to effective treatments for the condition.
Researchers discovered a non-invasive eye exam that can detect early signs of cognitive decline and cerebral small vessel disease, a major contributor to vascular dementia. The study found connections between altered retinal blood flow and changes in brain structure associated with the condition.
A study by UC San Francisco researchers found that patients with acute kidney injury on outpatient dialysis may not need lifelong treatment if they have the potential to recover. The study tracked data from over 1,700 patients and showed that approximately three-quarters of those who recovered kidney function discontinued dialysis with...
A new study found significant differences in cerebral blood flow and arterial transit time between women at different menopause stages and age-matched men. The researchers discovered distinct spatial distributions of these changes, with sex differences being more pronounced than any effect of menopause stage.
A large study of 74,471 patients found that those who quit smoking after percutaneous coronary intervention (PCI) have comparable rates of heart attacks, strokes, and deaths to non-smokers. However, heavy smokers showed no improvement in cardiovascular outcomes.
A wearable optical device using laser speckle imaging detects peripheral vasoconstriction caused by postpartum hemorrhage, providing an early warning system. The device shows promise in detecting heavy bleeding before it becomes severe, with a highly sensitive response to blood flow changes.
A large study published in Journal of Investigative Dermatology found that patients with severe psoriasis have a high prevalence of coronary microvascular dysfunction, which is associated with increased cardiovascular risk. Psoriasis severity and duration, as well as the presence of psoriatic arthritis, are independently linked to redu...
Researchers developed a new imaging technique using Bessel beam two-photon microscopy to detect stalling in brain capillaries, which can indicate acute neurological issues. The approach generates clear images of all capillaries every two seconds, providing better temporal resolution and enabling the detection of short stalling events.
A new study suggests that cerebral amyloid angiopathy (CAA), a common cause of spontaneous brain hemorrhages, can be transmitted via blood transfusion. Patients who received blood from donors with CAA were more than twice as likely to suffer a brain hemorrhage themselves.
A new CT test can identify individuals with stable angina at a reduced risk of three-year adverse outcomes despite having high coronary artery calcium scores. The test uses AI algorithms and computational fluid dynamics to simulate blood flow through the coronary arteries.
Researchers at Helmholtz Munich developed a non-invasive method using MR imaging to detect early signs of vascular disease associated with chronic pulmonary impairment in premature infants. The study presents a new tool for risk stratification and potential prevention of complications later in life.
Researchers found that severe COVID-19 survivors exhibit elevated muscle sympathetic nerve activity in response to mental stress, which accelerates heartbeat and increases blood pressure. This exaggerated reaction, combined with impaired vasodilation, poses a significant risk for cardiovascular complications.
The USC NRV Center performs complex revascularization procedures and conducts innovative research to treat debilitating conditions. The center will use the funding to enhance clinical care and education with a focus on technological innovation.
Researchers compared absorbency of 21 menstrual hygiene products using human red blood cells, finding that menstrual discs held the most blood, while super-absorbency period pants held the least. The study highlights the need for more research on menstruation to improve diagnostic accuracy and care for women.
Research reveals that high blood pressure disrupts artery cell messaging, causing arteries to remain constricted and limiting blood flow to the brain. The study provides a potential route for developing first-ever drug treatments for vascular dementia.
The study reveals altered magnitudes and coherence between oscillations in brain vasculature and brain waves in older adults. This finding has significant implications for the assessment of Alzheimer's disease and monitoring of neurodegenerative disorders.
A study of 200 people aged 50-70 found that higher carotene levels in the blood were associated with lower atherosclerosis and reduced cardiovascular disease risk. A diet rich in fruits and vegetables, particularly those high in carotenes, may help lower the risk of heart disease.
Researchers found that exercise-induced heart rate can cause plaque in moderately to severely blocked carotid arteries to migrate and halt blood flow to the brain. This can lead to ischemic stroke. The authors recommend checking arterial health regularly for people doing intense workouts.
Researchers developed an innovative imaging approach using two-photon microscopy to analyze retinal microcirculation, revealing significant changes in blood flow that may indicate brain diseases. The study suggests that microcirculation in the retina could serve as a promising predictor of cerebrovascular diseases.
A new study from Keck Medicine of USC reveals significant racial disparities in the diagnosis and treatment of peripheral artery disease (PAD) among Black and white patients. Black patients are nearly 50% less likely to receive vascular interventions, leading to a higher risk of stroke, heart attack, or amputation.
Birds experience flight-like sensations in their dreams during REM sleep, suggesting emotional content, while cerebral spinal fluid flow is disrupted. The study reveals similarities between bird and human sleep patterns, highlighting the importance of sleep for brain health and cognition.
Researchers at UCSF tested a nitroglycerin patch for treating menopausal women experiencing severe hot flashes. The study found short-term improvements, but benefits did not last past 12 weeks, with some side effects reported.
A Houston Methodist study found that COVID-19 variants and severity affect heart function, with microvascular involvement seen less often after nine months. The study recommends PET scans to check for microvascular dysfunction, which may be reversible.
Researchers at the Beckman Institute for Advanced Science and Technology have developed a new framework for super-resolution ultrasound using deep learning, reducing processing speeds from minutes to seconds. The new technology enables real-time blood flow visualization, overcoming challenges faced by conventional methods.
A novel low-profile pVAD system demonstrated 100% procedural success and no device-related adverse events in a first-in-human trial. The device supports cardiovascular hemodynamics with minimal hemolysis and low risk of vascular complications, aiming to minimize morbidity and improve patient outcomes
The study used magnetic resonance imaging (MRI) to measure acute pressure changes inside the heart, discovering that pressure increases when patients receive a specific medication called adenosine. This technology can help doctors better diagnose and monitor patients with heart disease and heart failure.