A team of researchers from USC and Caltech developed a new noninvasive tool to measure brain blood pressure, assessing stroke risk through changes in blood flow and volume during a stress test. The affordable, portable device has the potential to transform stroke care by providing more reliable data than existing questionnaires.
A study finds that cardiometabolic indicators like metabolic syndrome and diabetes impair coronary microvascular function, increasing cardiovascular risk. The presence of subclinical atherosclerosis also contributes to altered microvessel function.
A new study by University of Oklahoma researchers identifies key measurements of brain blood flow and ability to compensate as better predictors of mild cognitive impairment than traditional risk factors. The findings provide hope for preventing or treating memory problems early before they progress to dementia.
A team of UBC Okanagan researchers has created a new mechanical heart valve that combines the strengths of both mechanical and tissue replacement technologies, offering improved performance and durability.
The world's first combined whole eye and face transplant has demonstrated allograft survival, including rejection-free graft survival. The transplanted eye has maintained normal pressure, good blood flow, and some remaining structure and functions in the retina. Researchers are now focused on understanding how to restore sight.
A recent study from Waseda University found that short-duration, light-intensity exercises significantly increase oxy-Hb levels in the prefrontal cortex of children, indicating improved cerebral blood flow. This breakthrough suggests potential benefits for children's executive functions and brain development.
Researchers developed an air-powered computer that sets off alarms when certain medical devices fail, preventing blood clots and strokes. The device uses air to issue warnings, reducing costs and improving safety in healthcare settings.
A new mathematical method, validated with experimental animal data, provides fast, reliable, and minimally invasive way of determining how to treat critical blood pressure changes. The method accurately tracks cardiac output and systemic resistance, mirroring estimates from more invasive catheters in some cases.
A recent study at the University of Missouri discovered that oxytocin and corticotropin-releasing hormone cause the brainstem to become overactive, leading to hypertension. This finding can help develop targeted drugs to reduce high blood pressure in sleep apnea patients.
A study published in Circulation found that adults aged 50-54 with severely narrowed leg arteries had a higher risk of amputation after emergency surgery than those aged 80-84. This contradicts the traditional belief that older people are at increased risk.
A novel, star-shaped polymer has been developed as a low-volume resuscitant for prehospital treatment of severe hemorrhagic shock. The solution can refill blood vessels without disrupting coagulation, offering an improvement over existing colloidal resuscitants.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateJul 3, 2024
A study of over 4,500 healthy adults aged 60 and older found that nearly 28% had some form of heart valve disease, with age being the main risk factor. The majority of cases were mild, but the study highlights the need for more research into screening methods to identify and manage the disease in the elderly population.
Researchers found that hospitals that implemented standardized protocols from the American Heart Association and American Stroke Association saw significant reductions in stroke treatment times. The protocols, which include specific limits on time between symptom onset and hospital arrival, helped medical teams respond more quickly to ...
Researchers find that a repurposed drug, crizanlizumab, stabilizes vision in patients with retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) after two years of treatment. The study suggests that this may give patients additional years to read, drive, and enjoy activities.
A study by NIH-funded researchers visualizes the full network of blood vessels across the cortex of awake mice, revealing that blood vessels rhythmically expand and contract leading to 'waves' washing across the surface of the brain. The function of these waves remains a mystery.
Researchers found that the angle at which pulmonary veins reach the left atrial appendage affects blood flow and thrombus formation. The study used a sample of 130 patients to investigate the relationship between pulmonary vein morphology and thrombi risk in atrial fibrillation patients.
Researchers developed a wearable ultrasound patch that provides three-dimensional data on cerebral blood flow, addressing clinical standard limitations. The device offers hands-free, continuous monitoring and was tested on healthy volunteers with accurate results, paving the way for potential use in patients with neurological conditions.
A new study found that very early blood pressure lowering treatment can improve outcomes for patients with intracerebral hemorrhage, but worsen outcomes for those with ischemic stroke. Rapid diagnosis of the type of stroke is crucial in harnessing the benefits of this treatment.
Researchers discovered that IL-6 signaling in CD4-positive T cells promotes pulmonary hypertension development and progression. Treating mice with IL-6 inhibitors improved symptoms and decreased damage to the lungs and heart.
A new study found that brief anger episodes can negatively impact blood vessel function, leading to increased risk of heart disease and stroke. The researchers investigated the effects of anger, sadness, and anxiety on blood vessel function and found that evoking an angered state led to blood vessel dysfunction.
Randles developed computational tools to harness supercomputers, creating highly precise simulations of biophysical processes. Her work has direct impacts on patient care, including simulations of 700,000 heartbeats and cancer cells moving through the body.
Researchers have developed a pressure-alternating shoe insole that provides periods of rest to the soft tissues, thereby reducing the risk of diabetic foot ulcers. This innovative technology aims to mitigate the risk of complications from poor circulation and foot sores.
A new study found that a non-invasive imaging test can help identify patients with coronary artery blockage or narrowing who need a revascularization procedure. The test, called CT-FFR, uses CTA images and AI algorithms to model coronary blood flow, reducing the need for invasive procedures.
Researchers found that revascularization treatment significantly improves the quality of life for patients with chronic limb-threatening ischemia, a severe form of peripheral artery disease. The study revealed diminished quality of life among these patients, but revascularization restored sufficient blood flow and improved wellbeing.
Researchers have discovered that neurochemicals influence neural activity, blood flow, and fMRI measurements. The study found that certain neurochemicals can cause constrictions in blood vessels, leading to negative fMRI signals.
Bruno Scheller developed a procedure using drug-coated balloons to treat coronary and peripheral artery disease, improving patients' quality of life. The technique has been widely recognized and effective, with countless patients spared further pain and surgery.
Researchers developed a wearable device for non-invasive monitoring of hemodynamic indicators like heart rate, blood pressure, and oxygen saturation. The photoacoustic imaging watch offers valuable insights into disease diagnosis and treatment.
Researchers at the University of Virginia Health System are developing a technique to 'paint' tiny nanoparticles on transplanted veins to prevent blockages, potentially sparing patients from repeated surgeries. This approach could significantly reduce the number of vascular reconstructions performed annually in the US.
Scientists have developed fUSI technology that enables clinicians to see and map the spinal cord's response to treatments in real-time. This innovation offers improved monitoring of blood flow changes, potentially increasing treatment success rates and optimizing pain relief for patients.
Researchers at the University of Manchester have developed new methods to simulate blood flow, enabling faster and more accurate modeling of vascular diseases. These advancements have the potential to transform medical treatment and device innovation, providing real-time insights during surgical procedures and improving patient outcomes.
Researchers developed a test to predict which heart attack patients are likely to experience dysfunction after receiving mechanical pumps. The test measures pulmonary vascular compliance and its adaptability, helping doctors prevent right ventricle failure.
Researchers found that positioning stroke patients with large vessel ischemic strokes at 0-degrees resulted in significant improvements in neurological function compared to those with 30-degree head positioning. This approach optimized blood flow through the narrowed artery and improved collateral arteries, leading to better outcomes.
A study by Amsterdam UMC shows that Doppler ultrasound can detect placenta problems in small babies, identifying those at higher risk of oxygen deficiency and health issues. The measurement is added to the care plan for these undersized babies, allowing for better detection and monitoring of potential problems.
Researchers at Fralin Biomedical Research Institute and Carilion Clinic found that preserving leg vein grafts in heparinized arterial blood, rather than saline, improves their health and viability. This discovery could lead to better outcomes for patients undergoing coronary artery bypass graft procedures.
Experts recommend increasing the use of intravascular ultrasound (IVUS) in lower extremity revascularization procedures to optimize outcomes and reduce complications. The technique provides detailed information about vessel walls, plaque composition, and blood flow characteristics, enabling more accurate diagnosis and treatment planning.
Researchers used OCTA to visualize retinal blood vessel changes in migraine patients during and between attacks. Blood flow decreases were found, with asymmetrical flow correlated to headache pain side.
Researchers developed a physics-based metric to predict aortic aneurysm development, measuring 'fluttering' in blood vessels. The 'flutter instability parameter' forecasted abnormal growth three years prior to occurrence with 98% accuracy.
Researchers used NIRS to track oxygenated hemoglobin levels in infant brains responding to gentle touch. They found similar response times across age groups, but varying signal amplitudes that may be linked to changes in blood flow and erythropoietin production.
Eating fatty foods during stressful periods can reduce brain oxygenation and cause poorer vascular function in adults. Consuming low-fat food and drinks may help mitigate this effect.
Researchers at Temple University Health System report that the BASHIR Endovascular Catheter reduces blockages in lung arteries and correlates with improved right ventricle function, suggesting better survival outcomes. The catheter also shows significantly lower bleeding rates compared to other devices.
Biomedical engineers at Duke University created a new 'digital twins' framework using smartwatch data to capture personalized arterial forces over 700,000 heartbeats. This approach reduces the computational load by simulating tasks in parallel, enabling real-time tracking of cardiovascular disease progression and risk assessment.
A new study highlights how perimenopausal women's periods may become unpredictable, heavy, and cause worse premenstrual symptoms. The research suggests that improved education and support are needed to manage these changes, including extra support in the workplace, emotional support from loved ones, and access to support groups.
Multimodal neuromonitoring (MNM) tracks blood flow, pressure, oxygen and glucose levels in the brain to inform treatment decisions. MNM has improved clinical outcomes for patients with severe traumatic brain injuries at the University of Cincinnati.
Researchers are conducting a four-year study to investigate the effectiveness of acupuncture in reducing stable angina-related chest pain. The study will enroll 112 participants and compare acupuncture treatment to watching TED Talk videos for symptom relief.
Scientists have discovered a genetic pathway between the heart and brain tied to fainting, suggesting that the heart sends signals back to the brain that can change its function. The study found that vagal sensory neurons play a key role in fainting, with their activation leading to rapid pupil dilation, suppressed heart-rate and breat...
A study published in Annals of Neurology found that receiving clot-busting drug treatment in a mobile stroke unit (MSU) increases the likelihood of averting strokes and complete recovery compared to standard hospital emergency care. Patients treated by an MSU had faster treatment times, with nearly one-third recovering within 24 hours.
A new technique to control severe bleeding in injured patients has been found to increase the risk of death. The REBOA treatment was tested in a clinical trial involving 90 adult trauma patients, but it did not show the expected benefits.
A team of researchers discovered two genetic genes that predispose people to Raynaud's phenomenon: ADRA2A and IRX1. These variations cause small blood vessels to contract in response to stress or cold, leading to vasospasms and limited blood flow. The study could lead to effective treatments for the condition.
Researchers discovered a non-invasive eye exam that can detect early signs of cognitive decline and cerebral small vessel disease, a major contributor to vascular dementia. The study found connections between altered retinal blood flow and changes in brain structure associated with the condition.
A study by UC San Francisco researchers found that patients with acute kidney injury on outpatient dialysis may not need lifelong treatment if they have the potential to recover. The study tracked data from over 1,700 patients and showed that approximately three-quarters of those who recovered kidney function discontinued dialysis with...
A new study found significant differences in cerebral blood flow and arterial transit time between women at different menopause stages and age-matched men. The researchers discovered distinct spatial distributions of these changes, with sex differences being more pronounced than any effect of menopause stage.
A large study of 74,471 patients found that those who quit smoking after percutaneous coronary intervention (PCI) have comparable rates of heart attacks, strokes, and deaths to non-smokers. However, heavy smokers showed no improvement in cardiovascular outcomes.
A wearable optical device using laser speckle imaging detects peripheral vasoconstriction caused by postpartum hemorrhage, providing an early warning system. The device shows promise in detecting heavy bleeding before it becomes severe, with a highly sensitive response to blood flow changes.
A large study published in Journal of Investigative Dermatology found that patients with severe psoriasis have a high prevalence of coronary microvascular dysfunction, which is associated with increased cardiovascular risk. Psoriasis severity and duration, as well as the presence of psoriatic arthritis, are independently linked to redu...
Researchers developed a new imaging technique using Bessel beam two-photon microscopy to detect stalling in brain capillaries, which can indicate acute neurological issues. The approach generates clear images of all capillaries every two seconds, providing better temporal resolution and enabling the detection of short stalling events.
A new study suggests that cerebral amyloid angiopathy (CAA), a common cause of spontaneous brain hemorrhages, can be transmitted via blood transfusion. Patients who received blood from donors with CAA were more than twice as likely to suffer a brain hemorrhage themselves.
A new CT test can identify individuals with stable angina at a reduced risk of three-year adverse outcomes despite having high coronary artery calcium scores. The test uses AI algorithms and computational fluid dynamics to simulate blood flow through the coronary arteries.
Researchers at Helmholtz Munich developed a non-invasive method using MR imaging to detect early signs of vascular disease associated with chronic pulmonary impairment in premature infants. The study presents a new tool for risk stratification and potential prevention of complications later in life.
Researchers found that severe COVID-19 survivors exhibit elevated muscle sympathetic nerve activity in response to mental stress, which accelerates heartbeat and increases blood pressure. This exaggerated reaction, combined with impaired vasodilation, poses a significant risk for cardiovascular complications.
The USC NRV Center performs complex revascularization procedures and conducts innovative research to treat debilitating conditions. The center will use the funding to enhance clinical care and education with a focus on technological innovation.