Articles tagged with Blood Flow
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Researchers develop innovative data compression scheme to facilitate multispeckle diffuse correlation spectroscopy with high pixel resolutions, enabling non-invasive measurement of brain blood flow. The scheme uses field-programmable gate array compression to alleviate computational burdens and expand the use of SPAD cameras in biomedi...
Researchers successfully performed the first in-utero surgery to repair a potentially deadly developmental condition called vein of Galen malformation. The procedure involved treating an aggressive vascular malformation before birth, resulting in improved cardiac output and no signs of negative effects on the brain after birth.
A new onsite deep-learning based FFR-CT algorithm demonstrates excellent diagnostic performance, with high interobserver and intraobserver reproducibility. The algorithm showed AUC of 0.975, sensitivity of 93.5%, and specificity of 97.7% for hemodynamically significant stenosis.
A new high-speed two-photon microscope was developed with an unprecedented line scanning frequency of 400 kHz, achieving up to 10,000 frames per second. This allowed for precise observations of complex biological processes in living tissues, including calcium signal propagation and blood flow measurements.
A randomized controlled trial shows that a best endovascular treatment first revascularisation strategy is more effective in preventing major amputation and death than a vein bypass first strategy for patients with chronic limb-threatening ischaemia. The study, BASIL-2, recruited 345 patients from the UK, Sweden, and Denmark and found ...
Strokes can be largely prevented through education and lifestyle changes, such as moving more, healthy eating, and managing blood pressure. The American Stroke Association is launching a digital tool to educate people on stroke warning signs and risk factors, particularly for diverse populations.
Researchers have developed a non-invasive technique using laser speckle imaging to visualize microvasculature in donor hearts and detect abnormal blood flow. The method enables precise visualization of blood circulation, potentially identifying hearts suitable for transplantation.
Researchers discovered that parvalbumin interneurons secrete substance P, driving slow vasodilation and increasing blood flow in the brain. This process allows for waste removal and prevention of neurological dysfunctions like dementia.
A new study published in JAMA Network Open found that intensive blood pressure treatment significantly reduces the risk of adverse cerebrovascular events such as stroke. Participants with hypertension who received intensive treatment showed reduced white matter lesions and improved blood flow, indicating better overall brain health.
Researchers developed a dual-modality imaging technique combining photoacoustic and super-resolution ultrasound imaging to detect physiological and biochemical abnormalities. The new method provides comprehensive diagnostic information at a lower cost than traditional techniques.
Researchers found that correctly occluded left atrial appendages minimized left atrial flow stasis and thrombogenicity using 4D flow MRI and 3D phantoms. The study provides a clinical goal for the procedure in patients with atrial fibrillation.
A novel treatment approach called balloon pulmonary angioplasty has been shown to be effective in treating chronic blood clots in lung arteries. The procedure improves exercise capacity and quality of life, with some patients able to stop medications altogether. Refinements in technique have improved the procedure's safety and efficacy.
Researchers found decreased lung injury, coughing up blood, and mortality rates after balloon pulmonary angioplasty between 2013 and 2022. The minimally invasive procedure is now considered a safer option for inoperable CTEPH patients.
A multidisciplinary team of Emory researchers has discovered a key molecular pathway underlying COVID-19 organ damage in adults. The study found that high levels of fibrinogen cause red blood cells to clump together, damaging the endothelial glycocalyx and altering blood flow.
A WPI researcher is leading a three-year project to investigate the effects of stretching and blood flow on cardiovascular cells in tissue-engineered heart valves. The project aims to expand understanding of mechanical forces that propel cells in the body, with potential applications in other fields like cancer and wound healing.
Using image-based computational blood dynamics, researchers mimicked health conditions and investigated hemodynamic parameters to better understand how aneurysm size affects blood flow. They found that altered blood flow velocity distribution can lead to rupture, emphasizing the importance of early detection and treatment options.
A new study by Boston University researchers reveals that visual stimulation can induce large-scale changes in cerebrospinal fluid flow during wakefulness. The findings have implications for treating conditions like Alzheimer's disease, which are associated with declines in fluid flow.
Studies found that certain T cells in human blood can produce acetylcholine, regulating blood pressure and inflammation. Higher levels of these immune cells were associated with reduced risk of death in seriously ill patients.
A team of researchers has discovered new laws governing fluid flow through experiments on drinking straws, defying previously known resistance laws. The findings have promise for improving fluid handling in medical and engineering applications.
A new study shows that transcatheter mitral valve repair significantly reduces hospitalizations by almost 50 percent and death by nearly 30 percent in heart failure patients with severe mitral regurgitation. The procedure, using Abbott's MitraClip system, improves symptoms, reduces hospitalizations, and leads to longer survival.
Researchers at University Hospitals Cleveland Medical Center discovered that S-nitrosohemoglobin senses areas with insufficient oxygen and restores blood flow for oxygenation. This breakthrough opens up a new line of drug development to correct poor tissue oxygenation, including peripheral artery disease and sickle cell disease.
Researchers at Indiana University School of Medicine have identified a new type of cell called the vasculogenic fibroblast, which can help create new blood vessels for treatment. This discovery could lead to improved treatments for ischemic diseases such as diabetic wounds.
A new study found that stroke patients experience a daily rhythm in cerebral blood flow regulation, with greater regulation during afternoon hours compared to morning and night times. This discovery may improve health outcomes by guiding daily activity and personal care during stroke recovery.
A recent study published in the Journal of the American Heart Association found that irregular sleeping habits may increase the risk of developing atherosclerosis among adults older than 45. Maintaining regular sleep schedules can help reduce cardiovascular risk for aging adults and improve overall health.
A new neuroprotectant medication called ApTOLL has been shown to improve survival and reduce long-term disability among patients with stroke. The study found that ApTOLL, when used in conjunction with standard treatments, reduced death and brain damage, suggesting a promising new approach to treating stroke.
A study of over 350 patients with small vessel stroke found that the medications were well-tolerated and safe, suggesting potential benefits in improving patient outcomes. The results indicate that cilostazol and isosorbide mononitrate may help reduce recurrent stroke, cognitive impairment, and improve quality of life.
Researchers found no significant evidence of harm in lowering blood pressure targets after endovascular treatment, but trends suggested marginal benefit and potential worsening of long-term disability. Clinicians should consider auto-regulation of blood pressure unless above 180 mm Hg.
A large international clinical study found that patients with large strokes had significantly better recovery after endovascular thrombectomy plus medical management. The SELECT2 study showed almost 20% of patients who received thrombectomy regained functional independence, compared to 7% on medical treatment only.
Researchers at Aston University have discovered a new approach to process LDF light signals, allowing for more precise measurement of blood flow in specific areas of the vascular bed. This innovation has shown significant improvement in diagnostic accuracy for detecting microvascular changes in patients with type 2 diabetes and age-spe...
A new WVU study found nearly one in eight West Virginia infants had in utero exposure to opioids, stimulants, and/or cannabis between 2020 and 2022. The study showed a 40% increased risk of preterm birth among infants exposed to stimulants alone and a 70% increase with concurrent stimulant and cannabis exposures.
A new smartphone application called FAST.AI uses machine learning algorithms to recognize facial asymmetry, arm weakness, and speech changes in people experiencing a stroke. The app's accuracy was validated through a study involving nearly 270 patients with acute stroke, showing promise as a tool for prompt individuals to seek care.
A recent study found that recurrent stroke risk has declined over the past 20 years, with a greater decrease observed among women compared to men in South Texas. The study analyzed data from nearly 6,000 first-time ischemic stroke survivors and found that lifestyle changes and medication can help prevent recurrent strokes.
Research highlights underuse of dual blood thinners in women after minor stroke or transient ischemic attack (TIA), with potential benefits for stroke prevention. A study analyzed electronic health records of 2,953 adults and found that women were less likely to receive the treatment regimen, despite evidence suggesting its effectiveness.
Scientists have identified pericytes, a type of cell, that sense local energy needs and signal blood vessels to dilate, increasing blood flow. This process helps direct the brain's energy resources to support everyday functions.
A new American Heart Association scientific statement emphasizes the importance of rapid evaluation for TIA, which can lead to full-blown stroke. The statement offers a standardized approach to evaluating people with suspected TIA, including guidance for hospitals in rural areas with limited resources.
A recent study validated a remote access monitoring technology that predicts vascular access blockages in dialysis patients. The Vasc-Alert technology, developed by Henry Ford Hospital clinicians, shows promise in reducing thrombotic episodes and healthcare costs associated with dialysis access failures.
A new technique called πNIRS can monitor brain blood flow non-invasively using a fast two-dimensional camera. This method improves upon previous techniques like iNIRS, enabling faster detection of changes in blood flow related to neuronal activity.
A nationwide registry of AVM patients from 52 hospitals in mainland China investigated the efficacy of different treatments on patient groups. The study found that categorizing treatment strategies based on disease severity is an ideal approach, and a multidisciplinary comprehensive assessment promotes individualized treatment protocols.
A new injectable hydrogel has been developed to rapidly stop bleeding from traumatic wounds. The material becomes solid when injected into the body and can be easily washed away with a cold saline solution.
Researchers found that 'The Secret', a centuries-old folk medicine remedy, does not prevent bleeding after invasive coronary procedures. However, the study suggests that it may have therapeutic value due to its placebo effect, potentially providing stress relief for its believers.
A new PET imaging method is more effective than angiograms in determining the need for coronary stents or bypass surgery, according to UTHealth Houston researchers. The study confirms that PET threshold of severity at which stents and bypass surgery improve survival compared to medical treatment alone.
Researchers developed a novel optical technique to directly monitor cerebral oxygen consumption and blood flow in real-time. The technique uses phosphorescent probes to track the brain's oxygen gradient, providing valuable insights into brain activity and metabolism.
A new injectable hydrogel has been developed with enhanced shear-thinning properties, improved cellular biocompatibility, and significantly reduced clotting times. The biomaterial was created by adding sodium phytate to a gelatin-based compound, promoting even greater cohesion and triggering the initiation of blood coagulation.
Scientists have created a way to track brain diseases like depression, Alzheimer's, and strokes using fluorescent mouse blood. The method allows for months-long study of blood flow in the brain, providing new insights into disease progression and development.
Researchers developed an AI tool that analyzes plaque features on coronary CT scans to predict reduced blood flow, potentially reducing invasive tests. The tool could help doctors determine the next step in treatment plans and risk-stratify patients correctly.
A recent study found that restoring blood flow to the legs through bypass surgery or stent placement reduced pain and improved quality of life for people with peripheral artery disease (PAD). The Best Endovascular versus Best Surgical Therapy for Patients with Chronic Limb Threatening Ischemia Trial enrolled 1,830 participants and foun...
Researchers found that bypass surgery resulted in a 32% lower risk of major medical events related to CLTI, as well as significant reductions in repeat surgeries and amputations. Adults without optimal veins for the bypass had no significant differences in outcomes between open bypass and endovascular procedures.
Research at American Heart Association Scientific Sessions 2022 found that bypass surgery improves blood flow to legs and feet, reducing major amputations and repeat procedures by 65% and 27%, respectively. The study of 1,830 patients with chronic limb-threatening ischemia concluded that surgical bypass is a better option for those wit...
A new study found that a personalized 'precision' testing approach for people with stable chest pain led to more efficient evaluations and improved diagnosis of coronary artery disease. The approach involved assessing cardiovascular risk factors to identify low-risk individuals who may not benefit from further testing.
A clinical trial found that early use of ECMO devices did not improve outcomes for adults with rapidly deteriorating or severe cardiogenic shock. Participants who received immediate ECMO therapy showed similar clinical outcomes as those receiving early conservative therapy, including treatment with inotropes and vasopressors.
Researchers developed a model to simulate red blood cell destruction in high shear flows, revealing acceleration as a major factor. They recommend adding flow buffers to VADs to reduce hemolysis, aiming to improve hydraulic performance and patient outcomes.
A team of researchers at USC is launching a comprehensive study to investigate the connection between type 2 diabetes and dementia in adults with Hispanic ancestry. The five-year study will examine brain structure and activity, blood flow, blood glucose and insulin levels, and cognitive functioning in 200 participants.
A novel algorithm uses near-infrared spectroscopy to estimate intracranial pressure (ICP) based on hemoglobin levels. The research validates the accuracy of this method using invasive ICP data.
Researchers at Massachusetts General Hospital found that sedating patients after cardiac arrest can improve their chances of survival and regaining normal brain function. The study, conducted in mice, showed that sedatives like propofol and dexmedetomidine improved survival rates compared to those who received no sedation.
A new American Heart Association scientific statement emphasizes the importance of managing PAD based on a person's experience of symptoms, rather than relying solely on clinical measures. This approach aims to improve patient-centered care and outcomes, particularly for individuals with severe limb ischemia or comorbidities.
Aneurysms occur when blood vessel thins and expands, leading to increased stress on walls and rising rupture probability. The new model uses computed tomography scans to reconstruct geometry and blood flow patterns.
Researchers have developed a novel, non-invasive way to measure blood flow to the brains of newborn children at the bedside. This method uses real-time ultrasound color flow technique and 3D sampling to capture flow in a completely painless and safe manner.
Researchers at UVA Health have developed a new magnetic-resonance imaging (MRI) technique to track peripheral artery disease, which affects over 200 million people worldwide. The CEST approach produces comparable results to the current gold standard without requiring specialized equipment.
Researchers suggest special blood vessels called 'retia mirabilia' reduce brain pressure pulses, preventing damage. Computer modeling supports theory, which could be applied to other animals and humans.
Researchers at the University of East Anglia have developed a super-fast MRI scan that can diagnose patients with heart failure in record time. The new 4D heart MRI scan takes just eight minutes to produce detailed images of the heart valves and blood flow, helping doctors determine the best course of treatment.