Recent studies suggest that gamma brain wave stimulation can yield beneficial effects on brain function, disease pathology, and cognitive function in patients with Alzheimer's disease. Various cells beyond neurons are involved in mediating these effects.
Researchers at DOE's Pacific Northwest National Laboratory have discovered that adding a small amount of solid carbon to copper boosts its ability to conduct electricity. The findings could lead to more efficient electricity distribution, as well as more efficient motors for electric vehicles and industrial equipment.
A team of researchers identified a new structural class of antibiotics using an AI-powered platform built around explainable deep learning. The discovery shows potential to address antibiotic resistance, with the newly discovered antibiotics showing potent activity against multidrug-resistant pathogens.
Women who lost a parent early in life are more likely to experience adult separation anxiety and anxious attachment with romantic partners. These women tend to peak in anxiety levels within the first five years of relationships before declining after a decade.
A systematic testing approach for pesticides minimizes animal suffering while identifying potential harmful effects on brain cells. The four-phase test involves database research, laboratory experiments, animal species tests, and exposure to mice and rats.
A new study finds that tropical cyclone exposure is increasing globally, with vulnerable populations facing greater risks. The analysis reveals a significant increase in the number of people at risk from these storms, particularly among those over 60 and socioeconomically deprived.
Researchers at Scripps Research have found a way to modify picrotoxinin, a plant-derived toxin, with improved properties, making it easier to synthesize and modify. The modified version, 5Me-picrotoxinin, shows better chemical stability and is safer for humans.
Researchers at Linköping University have developed an aerogel material that can tune the transmission of terahertz signals between 13% and 91%, enabling various applications. The material's absorption property can be adjusted through a redox reaction, making it suitable for long-range signals from space or radar systems.
Reducing air pollution to pre-pandemic levels can protect Himalayan glaciers and prevent melting by the end of the century. Clean energy and lower-emission modes of transport would bring significant benefits for sustainable water supplies and ecosystems in Asia.
A team of scientists at Kanazawa University used high-speed atomic force microscopy to study the structural dynamics of sodium ion channels in cell membranes. They found that voltage sensor domains can dissociate from pore domains when the channel is in a resting state, leading to dimerization between neighboring channels. These findin...
Plant scientists have discovered a sophisticated RNA defense system that plants use to attack gray mold cells, sending mRNA molecules that disrupt fungal cellular processes. This innovative approach could lead to the development of eco-friendly fungicides with minimal environmental impact and no harm to humans or animals.
Researchers at the University of Michigan have developed blue phosphorescent OLEDs (PHOLEDs) that can maintain 90% of their blue light intensity for 10-14 times longer than other designs, making them potentially commercially viable. This breakthrough could enable the widespread use of blue PHOLEDs in OLED displays and lighting.
Researchers found that gentle electric currents on the back of the head improved skills in virtual reality and real-world surgical settings. Participants with stimulation showed a notable boost in dexterity, transferring skills from simulation to actual robot use.
Researchers at Uppsala University have identified nine distinct evolutionary lines among African lark species, revealing new species diversity. The study proposes splitting two known species into seven, while also confirming convergent evolution and diverging relationships among closely related species.
A new study from the University of Ottawa and Copenhagen Business School finds that removing human bias from organizational processes can lead to autonomous systems that create their own environments. This could limit human ability to recognize automation biases, notice environmental shifts, and take action.
The new intranasal mask, MV@GEL, intercepts viral aerosol particles with up to 93.2% effectiveness, providing broad protection against multiple viral variants. The mask's design uses positively charged hydrogel and cell-derived microsized vesicles featuring viral receptors.
The European Societies and European Journal of Cultural and Political Sociology journals will transition to diamond open access with the MIT Press, starting in 2025. The move is driven by the growing acceptance of open access in academic fields and the European Union's new requirements.
Researchers from Brazil discuss the management of refractory or relapsed classic Hodgkin lymphoma in adults, highlighting novel agents such as brentuximab vedotin and immunotherapy. The Brazilian healthcare system's constraints are also considered when making treatment decisions.
The eLTER PLUS project offers access to 43 long-term research sites in 19 European Countries through the Access Scheme. Researchers can visit sites for in-person visits (TA) or have protocols performed by local staff (RA). The call provides financial support and a set of predefined research questions within thematic categories.
A new study found that removing the RUNX1 transcription factor and its target gene can lead to a network collapse, causing cancer cell death in a type of aggressive leukemia. This breakthrough identifies specific protein targets for potential treatments.
A new study in the Journal of Dairy Science analyzes the life cycle of milk production in 47 small farms in Karnataka, India, identifying key emissions hotspots and potential sustainability improvements. The research highlights the importance of high-yielding animals and efficient feeding strategies to reduce carbon footprints.
Researchers found that the severity of muscle wasting depends on the location of the spinal cord injury. They also discovered that hypercortisolism, a hormonal imbalance, worsens muscle loss and can be targeted to rescue muscle tissue.
A new process developed by KIT researchers reduces steel production's greenhouse gas emissions by several hundred million tons per year. The technology, known as dry reforming, replaces coke with hydrogen-rich synthesis gas to support iron oxide reduction in blast furnaces.
New research reveals archery technology in the Andes dates back 5,000 years, coinciding with social complexity and village growth. The study analyzed over 1,000 projectile points and found a significant decrease in size around 5,000 years ago, suggesting a shift from spear-throwing to bow-and-arrow technology.
Researchers found a new species of fanged frog on Sulawesi Island, with males guarding eggs on leaves to keep them moist. The tiny frogs weigh about the same as a dime and have barely visible fangs, challenging previous assumptions about their reproductive behavior.
Researchers found a clear dose-response relationship between long-term topical corticosteroid use and elevated risks of osteoporosis and major osteoporotic fractures. Women under 50 had higher risks compared to men and other age groups, emphasizing the importance of careful treatment.
A growing number of studies have found that non-invasive sensory, electrical, or magnetic stimulation of gamma brain rhythms can reduce Alzheimer's pathology and its consequences. These studies have shown increases in gamma power, brain network connectivity, and improvements in memory, cognition, and sleep.
Researchers at the University of Cincinnati's Lindner Center of HOPE have developed a novel approach to treating depression using spinal cord stimulation. The study found that electrical stimulation of the spinal cord decreased depressive symptoms and showed therapeutic potential.
Researchers mapped medium- and high-entropy alloys' structure for the first time, identifying key factors that contribute to their unique combination of strength and flexibility. The study's findings could inform alloy design and unlock new properties in steel.
The PRIYA simulation suite provides a new model for simulating large-scale structure in the universe, constraining cosmological parameters and dark matter. The study confirms the σ8 tension between CMB measurements and weak lensing, with implications for understanding the universe's evolution billions of years after the Big Bang.
Scientists at CNRS found that flowering plants in farmland are evolving towards self-fertilization as insects decline. This phenomenon threatens plant-pollinator interactions, highlighting the need for conservation measures.
A research team at Texas Tech University Health Sciences Center discovered a unique sodium pump variant in brine shrimp that enables them to thrive in high-salinity environments. This NKA variant uses more energy than common variants, allowing the animal to maintain steeper Na+ gradients.
Researchers engineered bacteria to produce zeaxanthin and PDC simultaneously from underutilized plant fiber, offering a promising solution for sustainable biofuels. The discovery could lead to lower greenhouse gas emissions and improved economics in the production process.
Researchers identified Benidipine as a compound promoting the death of cigarette smoke-induced senescent lung cells, improving lung emphysema. The dihydropyridine family of calcium channel blockers constitutes a new class of senolytics that could improve lung diseases.
Researchers used deep learning models to identify compounds with strong antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA). The models were trained on expanded datasets and an algorithm that allows for explainable predictions, enabling the discovery of potent antibiotics with minimal human toxicity.
A large randomized study investigated the effect of preoperative, low-dose oral administration of midazolam in older patients on patient satisfaction and safety. No significant difference was found between midazolam and placebo groups regarding patient safety.
A new study by researchers at New York University found that searching online to evaluate the truthfulness of false news articles actually increases the probability of believing misinformation. This phenomenon is concentrated among individuals for whom search engines return lower-quality information.
The Association for Molecular Pathology published a report outlining considerations for a slice testing strategy, including gene selection and quality. This approach combines the advantages of high-quality gene panels with flexibility and broad scope of exome sequencing.
Scientists use new photography technique to observe interaction between biological cell and shock wave, revealing high-speed phenomena. The technology has potential applications in science, medicine, and industry.
Researchers at MMRI have developed a novel approach to minimize cardiac damage after a heart attack by targeting the spleen with histone deacetylase inhibitors. This targeting strategy results in a significant decrease in cardiac scar size and preservation of heart function, even after just one dose.
The Coscientist AI system has been successfully designed, planned, and executed a chemistry experiment, demonstrating its potential to revolutionize scientific research. By leveraging large language models and cloud lab technology, Coscientist can automate the experimental process, enabling scientists to design and run experiments much...
A US epidemiological study found that increased waist measurements are linked to a higher risk of female infertility. Physical activity has been shown to potentially mitigate this risk, suggesting a potential protective effect.
Researchers at the University of Sussex have discovered transformative nanomaterials with potential for clean energy production and building materials on Mars. Using sustainable production methods, they turned a waste product into nanobelts that could provide clean energy and sustainable electronics.
A new AI system, Coscientist, has demonstrated its ability to autonomously learn about Nobel Prize-winning chemical reactions and design successful laboratory procedures. The system achieved this in just a few minutes, outperforming human chemists in some cases.
Researchers at Baylor College of Medicine have developed a community health report that analyzes the human virome in wastewater, providing valuable insights into emerging diseases. By detecting changes in viral trends in wastewater, scientists can identify outbreaks and transmission patterns, ultimately improving population health.
A recent study found that alterations in the human microbiome, including those in the gut, urinary, and salivary tracts, are linked to kidney stone formation. The research team discovered changes in these microbiomes were common among patients with kidney stones.
A recent study found that decreases in the number of formerly abundant insect species have contributed significantly to local insect declines. The study's findings challenge the idea that changes in insect biodiversity result from rarer species disappearing.
Researchers have discovered the structural proof of DNA and RNA breakdown by PLD3, an enzyme linked to Alzheimer's disease. The study provides a map of the protein, which could lead to better understanding of its role in certain diseases.
A study published in Neurology found that white matter hyperintensities in former football players are associated with greater vascular risk factors, brain shrinkage, and other markers of dementia. The study suggests that brain scans may be a promising tool to study the long-term effects of repetitive head impacts.
VirCapSeq-VERT, a next-generation sequencing-based screening and surveillance system, can detect any virus that can potentially infect humans with greater sensitivity and speed than other NGS platforms. The technology achieved clinical sensitivity of 99 percent and 100 percent clinical specificity in a validation study.
A recent study published in Nature reveals that mitochondrial dysfunction disrupts dietary lipid processing in enterocytes, leading to abnormal fat accumulation and impaired nutrient delivery. The findings provide new insights into the gastrointestinal symptoms of mitochondrial disease and may lead to novel therapeutic approaches.
Researchers found that ChatGPT generated only 32% of acceptable questions with correct answers and explanations. The AI model struggled to provide explanations for incorrect answers, raising concerns about its effectiveness in medical education. Despite limitations, the study suggests that ChatGPT may still be useful for creating pract...
A study by University of Eastern Finland finds that integrating AI systems into service teams increases demands on middle management, requiring balancing acts and new skills. The study also highlights the need for human managers to focus on innovations and development while AI handles routine tasks.
A Mediterranean diet has been found to be a straightforward and effective approach for improving IVF success rates, with high intakes of fruits, vegetables, whole grains, and omega-3 fatty acids. The diet's benefits were seen in both embryo development and pregnancy outcomes, even after just six weeks of implementation.
Researchers at UTA discovered that using carbonated water in chromatography reduces the technique's Analytical Method Greenness Score (AMGS) making it safer for the environment. The study also showed that carbonated liquids are just as fast and efficient as other liquids used in chromatography.
A moderate low-carbohydrate diet has been shown to lower average blood sugar levels and increase time spent within the target glucose range without adverse effects. Participants experienced improved glucose control and felt more satisfied with the new diet.
Researchers at Helmholtz Munich have discovered a new relationship between DNA replication timing and cellular plasticity, allowing for the potential reprogramming of cells. The study found that the three-dimensional structure of the genome influences the flexibility of the replication timing program.
A new study has shed light on the convergent evolution of defensive enrollment in arthropods by analyzing 3D-preserved trilobite soft tissues. The fossils, which date back to the Ordovician Period, show that trilobites used a unique mechanism to protect their vulnerable soft tissues with their hard exoskeletons.
A team of scientists has developed a method to synthesize large-area 2D materials with atomic thickness, exposing single facets. These samples exhibit high crystallinity and ordered domain orientation, making them ideal candidates for studying facet-dependent properties.
Researchers at Tokyo Medical and Dental University have developed a novel method to characterize protein-binding interfaces, revealing complex protein geometries. The technique was validated by studying the homophilic interaction between LAMP2A molecules, which form a trimeric structure in mammalian cells.