Knowing family health history is crucial for reducing heart attack and stroke risk. Experts recommend following Life's Essential 8 - five health behaviors and three health factors to lower genetic risks.
Min Li will receive the 2024 Palade Prize for his contributions to pancreatology, recognizing his pioneering work on pancreatic cancer and metabolic reprogramming. He has been continuously funded by the National Cancer Institute for 15 years and has published over 200 high-impact articles.
Lantidra is the only FDA-approved treatment for brittle type 1 diabetes, a more severe form of the disease. The therapy involves pancreatic islet cell transplantation and has shown promising results in clinical trials, with most patients no longer requiring insulin one year after the procedure.
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
The Mount Sinai Health System has received the 2024 CHIME Digital Health Most Wired recognition as a certified level 9 in acute care and level 8 in ambulatory care. The system leverages digital health solutions to enhance patient care and reduce administrative burden.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·DateNov 25, 2024
A nearly century-old study on employee productivity is reevaluated in a new dissertation, highlighting the unscientific basis of human relations school. The study's findings, led by Elton Mayo, have been widely accepted as scientific fact but are actually based on storytelling and deception.
A team of researchers discovered fossil amphibians preserved in cylindrical burrows in Wyoming, providing insights into their adaptation to extreme seasonal conditions. The ancient creatures, about a foot long, had underdeveloped arms and likely used their heads to dig burrows during the dry season.
The partnership will equip primary care teams with the Cognitive Health Assessment (CHA) tool to detect dementia and provide comprehensive care. With the goal of reducing wait times for specialist care in California by 2050, the collaboration aims to improve brain health and support patients and families through early detection and edu...
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Daniel Oropeza, an assistant professor at UC Santa Barbara, has been awarded a $1 million grant to research near-net-shape fabrication of high-density ceramics. His team aims to create complex geometries using a multi-material deposition system and hot pressing, which could lead to the development of new materials for extreme environme...
SourceUniversity of California - Santa Barbara·DateNov 25, 2024
The research project BIOntier aims to develop more environmentally friendly materials with advanced technological solutions. UC3M participates as leader of the experimental characterisation work package, combining experimental analysis and computational simulations.
A new report by Symplectic showcases how research information management systems drive academic-industry partnerships, highlighting the benefits of collaboration for both parties. The report explores successful strategies and technologies used by universities and industry partners, including Digital Science's solutions.
The partnership aims to enhance education, workforce development, and community health services through collaborative efforts. The initiative bridges academic knowledge with practical applications, offering significant benefits for students and the local public health workforce.
SourceUniversity of Michigan School of Public Health·DateNov 25, 2024
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
The Andy & Barbara Gessner College of Nursing has achieved a 100% first-time pass rate on the NCLEX-RN exam, ranking No. 1 in Texas and nationwide. This marks the fifth consecutive year the college has reached this milestone.
The Funding Atlas 2024 shows an increase in university funding from €26.7 billion in 2022 to €28.4 billion in 2019, with third-party funding rising by 19.1% over the same period. The federal government is the largest source of third-party funding, while industry share continues to decline.
Case Western Reserve University has received a $1.5 million grant to study vaginal bacterial infections, which are linked to preterm birth, gynecological malignancies, and sexually transmitted diseases. The researchers aim to identify effective treatments and prevent recurrences.
The University of Rhode Island-based report card gives failing grades to over half the world's countries, with a median score of 52. Democratic countries tend to have better human rights records, but exceptions exist. The US scored a 62.5, ranking 66th, despite being a wealthy democratic country.
The National Center for Supercomputing Applications (NCSA) has received the Readers' Choice Award: Best HPC Collaboration and Editors' Choice: Best Use of HPC in Physical Sciences. This is the 14th consecutive year NCSA has been honored with an HPCwire award.
SourceNational Center for Supercomputing Applications·DateNov 25, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
The NYU-CUNY Prevention Research Center will improve diabetes management among low-income immigrant populations through culturally tailored education and support. The center aims to enhance capacity for community partners to adopt and implement evidence-based interventions effectively.
SourceCUNY Graduate School of Public Health and Health Policy·DateNov 25, 2024
Despite survey findings, US adults trust store-bought turkey to be contaminant-free, but more than half test positive for fecal bacteria. Experts recommend avoiding potentially contaminated turkey and opting for plant-based alternatives.
SourcePhysicians Committee for Responsible Medicine·TypeSurvey·DateNov 25, 2024
The Hamilton and Amabel James Center for Artificial Intelligence and Human Health solidifies Mount Sinai's leadership in delivering patient care through innovative AI tools and technologies. The interdisciplinary center combines AI, data science, and genomics to revolutionize diagnosis and treatment.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·DateNov 25, 2024
The Deutsche Forschungsgemeinschaft is establishing seven new Collaborative Research Centres (CRC) with a total funding of €92 million. The CRCs focus on innovative research projects in sustainable construction, electronic systems, and ecosystem services. Seven new Transregios are also being funded to tackle long-term challenges.
A team of researchers developed an exascale climate emulator that offers faster, radically enhanced high-resolution simulations without massive data storage needs. The emulator uses mixed-precision arithmetic to preserve accuracy and improve performance.
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A wearable electrical nerve stimulation device has been shown to provide significant relief from long COVID symptoms such as pain and fatigue. Researchers found that the high-dose TENS group experienced notable improvements in pain relief and walking ability.
SourceUniversity of California - Los Angeles Health Sciences·JournalScientific Reports·TypeRandomized controlled/clinical trial·DateNov 25, 2024
Researchers found that GLP-1 receptor agonists reduced the risk of kidney failure by 16% and worsening of kidney function by 22%. The combined reduction in risk was 19%, showing a clear benefit on kidney protection. This study expands current knowledge about this class of drugs, highlighting their role in treating patients with chronic...
SourceGeorge Institute for Global Health·JournalThe Lancet Diabetes & Endocrinology·TypeMeta-analysis·DateNov 25, 2024
A new study suggests that a cancer peer support program called Stronger Together improved psychological outcomes, as well as overall quality of life, among patients with breast and gynecological cancers in Vietnam. The program showed promise for providing critical social support in low-resource settings.
SourceBoston University School of Public Health·JournalJCO Global Oncology·TypeObservational study·DateNov 25, 2024
Researchers developed an adapted nominal group technique (aNGT) to efficiently build consensus among diverse stakeholders, prioritizing key domains and identifying new care indicators. The approach was effective in reaching a consensus on prioritizing symptoms, functioning, and quality of care.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 25, 2024
The new atlas, developed by the University of Illinois and West University of Timișoara, offers a comprehensive database of 427 crayfish taxa and over 100,000 observation records. This resource will facilitate informed conservation decisions and support efforts to mitigate the impact of invasive species on freshwater ecosystems.
SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalPeerJ·DateNov 25, 2024
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
This special report highlights the importance of expanded training for family physicians to address the physical and psychological effects of war. Family physicians must be prepared to provide timely, accurate information and foster understanding and reconciliation in the midst of conflict.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 25, 2024
Researchers at UTIG develop a computer model to detect oceans in Uranus' moons by analyzing small oscillations in their spin. The technique could reveal liquid water worlds throughout the galaxy, potentially harboring life.
SourceUniversity of Texas at Austin·JournalGeophysical Research Letters·TypeComputational simulation/modeling·DateNov 25, 2024
A new approach profiles gene activity in the living brain, providing insights into neurological conditions like epilepsy. The study enhances understanding of seizure networks, potentially improving surgical interventions.
A cohort study found that long-term exposure to wildfire and fine particulate matter was associated with dementia diagnoses. The study suggests that reducing wildfire PM2.5 exposure could decrease dementia diagnoses and address health disparities.
A genetic key to understanding mitochondrial DNA depletion syndrome has been identified, revealing mechanisms for improved diagnosis and treatment. The research highlights the crucial role of the MICOS10 gene in maintaining mitochondrial structure and function.
SourceJuntendo University Research Promotion Center·JournalLiver International·TypeCase study·DateNov 25, 2024
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers argue that the planets' unique magnetic fields can be explained by immiscible layers of water and hydrocarbons. Computer simulations show that a combination of water, methane, and ammonia separates into two distinct layers under extreme temperatures and pressures.
SourceUniversity of California - Berkeley·JournalProceedings of the National Academy of Sciences·DateNov 25, 2024
A new nitrification inhibitor, copper pyrazole, has been developed to slow down the nitrification and denitrification processes in nitrogen transformation. The study found that copper pyrazole reduces urease activity and lowers the levels of key genes involved in nitrogen cycling.
SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalFrontiers in Microbiology·DateNov 25, 2024
The journal Technology in Horticulture has been successfully indexed in ESCI, enhancing its discoverability and potential indexing in higher-ranked databases. This recognition promotes open-access content and academic exchange worldwide.
SourceMaximum Academic Press·JournalTechnology in Horticulture·DateNov 25, 2024
Researchers at UCL found that excess brain volume loss with amyloid-targeting immunotherapies is associated with therapy effectiveness, not harm. The 'amyloid-removal-related pseudo-atrophy' or ARPA phenomenon suggests that removal of amyloid plaques may be the cause of observed brain changes.
SourceUniversity College London·JournalThe Lancet Neurology·DateNov 25, 2024
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A study found that ChatGPT provides higher fatality numbers when asked in Arabic compared to questions in Hebrew, highlighting the impact of user language on information dissemination. The researchers believe this has profound social implications, as it can shape perceptions of conflict and fuel biases.
SourceUniversity of Zurich·JournalJournal of Peace Research·TypeData/statistical analysis·DateNov 25, 2024
A recent study led by the University of Washington found that higher long-term exposure to wildfire smoke is associated with a significant increase in the odds of developing dementia. The researchers analyzed health records of 1.2 million Southern California residents and found that exposure to wildfire PM2.5 increased the risk of deme...
SourceUniversity of Washington·JournalJAMA Neurology·TypeObservational study·DateNov 25, 2024
A modeling study found that HPV vaccination programs for adults aged 27-45 years are more costly and less effective than vaccinating younger people. Vaccinating subgroups at higher risk of HPV infection may improve cost-effectiveness, but overall, it's unlikely to be efficient for cancer prevention.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeNews article·DateNov 25, 2024
A new study found that local and non-Anglo artist representation in Australian charts has declined since the rise of digital streaming. Indigenous music from Australia and New Zealand saw a significant decline in singles chart share, from 16.6% to 2.5%, while albums chart share also decreased.
SourceDe Gruyter·JournalInternational Journal of Music Business Research·TypeData/statistical analysis·DateNov 25, 2024
Scientists have captured 3D snapshots of individual RNA nanoparticles in motion, showcasing the dynamic and intricate folding process. This breakthrough uses advanced electron microscopy to study RNA's flexibility, enabling new insights into its structure and potential applications in molecular medicine.
SourceAarhus University·JournalNature Communications·TypeExperimental study·DateNov 25, 2024
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
This issue of Annals of Family Medicine highlights the complexity of war's effects on family doctors and patients. Research reveals the significant impact of trauma on healthcare professionals in Israel following a terrorist attack, highlighting burnout and well-being concerns. The article also shares challenges faced by physicians in ...
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 25, 2024
Researchers discovered a new component of the peripheral nervous system that acts by increasing energy metabolism in the body. This finding paves the way for simpler and cheaper drugs to control obesity and weight gain.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalNature·DateNov 25, 2024
Researchers have developed a game-changing catalyst using topological chiral crystals to manipulate electron spin, accelerating the water splitting process and improving hydrogen production efficiency. The breakthrough could make renewable energy technology more viable, bringing us closer to a clean energy future.
SourceMax Planck Institute for Chemical Physics of Solids·JournalNature Energy·TypeExperimental study·DateNov 25, 2024
A study found that Oregon's COVID-19 stay-at-home order led to a significant increase in reported health-related social needs, including housing and food. The analysis suggests that public health interventions are needed to address these persistent needs.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 25, 2024
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
In-shell pecans are susceptible to pathogens due to soil contact with wildlife and livestock. A recent study found that hot water treatment significantly reduced Shiga toxin-producing E. coli populations on pecans, regardless of treatment time, and prevented cross-contamination.
SourceUniversity of Arkansas System Division of Agriculture·JournalJournal of Food Protection·TypeExperimental study·DateNov 25, 2024
Researchers used fitness tracker data and machine learning to detect bipolar disorder mood swings with 80.1% accuracy for depression and 89.1% accuracy for mania. The study's findings move the field toward personalized algorithms suitable for all patients, regardless of compliance or device access.
SourceBrigham and Women's Hospital·JournalActa Psychiatrica Scandinavica·TypeObservational study·DateNov 25, 2024
Researchers found that cyanobacteria use variations in pulse amplitude to convey information in single cells, regulating genes and controlling cellular processes. This discovery sheds light on how biological rhythms work together to coordinate cellular functions.
SourceUniversity of Cambridge·JournalCurrent Biology·TypeExperimental study·DateNov 25, 2024
A recent study from Stanford University reveals that dopamine and serotonin work together, but also in opposition, to shape behavior. Researchers found that dopamine signals increase with reward prediction while serotonin signals decrease, but only when both systems are active can animals learn to link cues with rewards.
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
A team of researchers successfully demonstrated nonlinear Compton scattering using a multi-petawatt laser, producing ultra-bright gamma rays. The achievement offers new insights into high-energy electron-photon interactions without traditional particle accelerators.
SourceInstitute for Basic Science·JournalNature Photonics·TypeExperimental study·DateNov 25, 2024
Researchers identified acute effects of cigarette and e-cigarette smoking on vascular function, including decreased blood flow velocity and venous oxygen saturation. The study found that vaping with and without nicotine led to significant changes in vascular function, highlighting the potential harm of vaping even without nicotine.
SourceRadiological Society of North America·DateNov 25, 2024
Researchers found that ancient rock painting sites by water generated strong echoes that could be heard by people approaching the site. The echoes allowed prehistoric hunter-gatherers to perceive their surroundings in a unique sensory environment. This discovery sheds light on the importance of sound reflections in past societies.
SourceUniversity of Helsinki·JournalSound Studies·DateNov 25, 2024
Researchers at Cold Spring Harbor Laboratory have devised a potential solution to the paradox of animal innate abilities using artificial intelligence. The genomic bottleneck algorithm allows for compression levels unseen in AI, enabling faster runtimes and potentially leading to more evolved AI systems.
SourceCold Spring Harbor Laboratory·JournalProceedings of the National Academy of Sciences·DateNov 25, 2024
A new study published in JAMA found that women who experience severe maternal morbidity during their first pregnancy are less likely to have more children. The research, which studied over a million women in Sweden, revealed that such events can have a lasting impact on fertility.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A randomized phase 3 trial found that adding temozolomide to radiation therapy improves long-term survival for adult patients with low-grade gliomas. The 10-year survival rate was 70% with combined treatment, compared to 47% with radiation alone.
SourceECOG-ACRIN Cancer Research Group·JournalJournal of Neuro-Oncology·DateNov 25, 2024
Researchers at the University of Rochester Medical Center have discovered a potential biomarker for psychosis diagnosis by analyzing brain connectivity patterns. The 'somato-visual' biomarker shows promise in predicting psychosis onset and stratifying patients into clinically meaningful subgroups.
SourceUniversity of Rochester Medical Center·JournalMolecular Psychiatry·DateNov 25, 2024
Researchers discovered that bats can navigate through obstacles even with their critical auditory pathway temporarily blocked. The bats adapt by changing their flight path and vocalizations, suggesting an innate ability to launch a Plan B in times of diminished hearing.
SourceJohns Hopkins University·JournalCurrent Biology·DateNov 25, 2024
A new AI tool generates realistic satellite images of future flooding, which can help communities visualize and prepare for approaching storms. The method combines a generative artificial intelligence model with a physics-based flood model, producing more accurate and realistic images than an AI-only approach.
SourceMassachusetts Institute of Technology·JournalIEEE Transactions on Geoscience and Remote Sensing·DateNov 25, 2024
Researchers developed an artificial intelligence model that selects the best phage cocktail for a given patient based on their genome. The model was tested on a new collection of E. coli strains responsible for pneumonia and showed high success rates.
SourceInstitut Pasteur·JournalNature Microbiology·TypeExperimental study·DateNov 25, 2024
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers found that individuals with depression who engage in reflexive emotion regulation experience increased suicidal thoughts during daily stressful events. In contrast, adaptive responses to stress were observed when participants used reappraisal strategy.
SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeImaging analysis·DateNov 25, 2024
The updated ASTRO guideline recommends personalized treatment approaches for patients with locally advanced rectal cancer, including non-surgical alternatives and intensified treatment regimens. The guideline aims to improve outcomes while preserving quality of life.
SourceAmerican Society for Radiation Oncology·JournalPractical Radiation Oncology·DateNov 25, 2024
A new study finds that those who feel powerful in their relationships are less dependent on others, think more highly of themselves, and are more confident that they are desirable. This can lead to a higher interest in alternative partners and a greater willingness to engage in infidelity.
SourceUniversity of Rochester·JournalArchives of Sexual Behavior·TypeExperimental study·DateNov 25, 2024
Researchers discovered Inceptor's role in regulating insulin homeostasis and its potential to improve beta cell function. By blocking Inceptor, the receptor can refill beta cells' insulin stores and enhance insulin release.
SourceHelmholtz Munich (Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH))·JournalNature Metabolism·DateNov 25, 2024
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers tested ODS FeCrAl alloys in a liquid LiPb environment and found that they form durable γ-LiAlO2 layers, which provide strong resistance to corrosion. The study's findings are crucial for improving material durability in fusion reactors and high-temperature energy systems.
SourceInstitute of Science Tokyo·JournalCorrosion Science·TypeExperimental study·DateNov 25, 2024
A new study identified inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug as a potential treatment for Alzheimer's. The approach successfully counteracted cognitive decline and brain damage in animal models, including genetically modified mice.
SourceUniversita Cattolica del Sacro Cuore·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateNov 25, 2024
Research at Linköping University shows that people distance themselves from neutral products if they are liked by those with opposing political views. This phenomenon affects choices even when irrelevant to politics. The studies also found that people unconsciously behave this way to maintain a consistent self-image.
SourceLinköping University·JournalPersonality and Social Psychology Bulletin·TypeSurvey·DateNov 25, 2024
Researchers have developed a method to convert black polystyrene waste into reusable starting materials using sunlight or white LEDs. The technique involves adding carbon black and exposing the mixture to high-intensity light, resulting in efficient breakdown of polymer bonds.
SourceAmerican Chemical Society·JournalACS Central Science·DateNov 25, 2024
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A new UBC-led study reveals that preserving key natural ecosystems across Canada can significantly reduce rainwater runoff and protect homes and livelihoods. The research identifies 201,000 square kilometres of watersheds as critical for flood prevention, supporting wildlife while reducing reliance on costly infrastructure.
SourceUniversity of British Columbia·JournalEcosystem Services·TypeData/statistical analysis·DateNov 25, 2024
Researchers developed a platform to produce mature, uniform organoids using a three-dimensional engineered membrane. This breakthrough enables consistent quality and improved efficiency for practical applications in clinical trials and drug development.
SourcePohang University of Science & Technology (POSTECH)·JournalNature Communications·DateNov 25, 2024
Researchers have observed a rare metal-poor supernova, providing valuable information about the early universe. The study revealed that this supernova was distinct from others in nearby galaxies, with unique properties such as a steady brightness period and rapid spin.
SourceOhio State University·JournalThe Astrophysical Journal·DateNov 25, 2024
A groundbreaking study has revealed insights into the evolution of flowering plants and their reproductive strategies. The Amborella trichopoda genome provides valuable information on the genetic underpinnings of plant diversity, shedding light on the mechanisms that determine plant sex.
SourceHudsonAlpha Institute for Biotechnology·JournalNature Plants·TypeData/statistical analysis·DateNov 25, 2024
Researchers have developed an algorithm-based scheme to help drivers avert drowsiness, which contributes to thousands of fatal incidents and injuries every year. The system uses EEG signal detection and machine learning algorithms to achieve high accuracy and reduce training time.
SourceUniversity of Sharjah·JournalBiomedical Signal Processing and Control·TypeComputational simulation/modeling·DateNov 25, 2024
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A new approach to first trimester obstetrical care combining point-of-care ultrasound and immediate multidisciplinary care has reduced emergency visits by 81%. This integration allows for timely diagnosis of abnormal pregnancies, improved education and support for all patients, including those experiencing miscarriage.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 25, 2024
The study found that irritability was the most common systemic reaction in children under 2 years, followed by fever and fatigue or sleepiness. Maternal vaccination is thought to be a factor in the higher prevalence of reactions after the first dose.
SourceJAMA Network·JournalJAMA Network Open·DateNov 25, 2024
A digital sensing-based monitoring system was developed to maintain small- and medium-sized aging bridges in Vietnam, improving accuracy and user-friendliness. The system achieved an accuracy of over 95% in measuring vertical displacement and actual deflection results.
SourceNational Research Council of Science & Technology·DateNov 25, 2024
A new study has revealed a hidden pocket inside the TAS2R14 bitter taste receptor, which can recognize and respond to a wide variety of compounds. This discovery could lead to new ways of designing medications that target these receptors, potentially helping to treat conditions like asthma and inflammation.
SourceThe Hebrew University of Jerusalem·JournalNature Communications·TypeExperimental study·DateNov 25, 2024
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new study led by Thomas Jefferson University researchers highlights critical healthcare gaps that hinder long-term recovery for people living with OUD in Philadelphia. The study identifies challenges such as lengthy and restrictive assessment processes, inadequate operating hours, and lack of sufficient withdrawal management as barri...
SourceThomas Jefferson University·JournalJournal of Substance Use and Addiction Treatment·DateNov 25, 2024
A new whole-genome study challenges the long-held belief that Armenians are descendants of Phrygian settlers from the Balkans. Instead, researchers found a genetic input into the region from Neolithic Levantine farmers, suggesting a large-scale post-Early Bronze Age migration wave across the Middle East.
SourceTrinity College Dublin·JournalAmerican Journal of Human Genetics·DateNov 25, 2024
Researchers at Medical University of South Carolina and University of Florida developed a novel approach to treat type 1 diabetes using tagged beta cell transplant with localized immune protection. The study, published in Cell Reports, shows promise for creating an off-the-shelf solution for T1D treatment.
SourceMedical University of South Carolina·JournalCell Reports·DateNov 25, 2024
A new study by UCL researchers found that mothers who regularly describe their child's thoughts and feelings have higher oxytocin levels in infants. The hormone oxytocin plays a crucial role in social relationships and bonding between parents and children.
SourceUniversity College London·JournalDevelopment and Psychopathology·DateNov 25, 2024
A new study warns that climate change's impact on water resources will significantly increase the cost of achieving zero-emission grids by 2050. The required investments in generation and transmission infrastructure are expected to be massive, with up to 139 gigawatts of power capacity needed in the Western United States.
SourceUniversity of California - San Diego·JournalNature Communications·TypeComputational simulation/modeling·DateNov 25, 2024
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers identified a novel role for the locus coeruleus in facilitating transition between NREM and REM sleep states while maintaining unconscious vigilance. Stress disrupts its functions, negatively impacting sleep quality. The study provides crucial insights into sleep disorders and could lead to improved treatments.
SourceUniversity of Lausanne·JournalNature Neuroscience·TypeExperimental study·DateNov 25, 2024
Researchers analyzed chromosomal chaos in leukemia cells and found that genetic and non-genetic factors drive functional heterogeneity. They identified therapeutic targets and alternatives for resistant subclones, providing a model for early identification of leukemia stem cells.
SourceGerman Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)·JournalNature Genetics·DateNov 25, 2024
A Tel Aviv University study finds that individuals who enhance their appearance are more likely to exhibit prosocial behavior, including donating to charity. The research suggests that feeling attractive can motivate people to engage in good deeds, with a significant impact on social consciousness.
SourceTel-Aviv University·JournalInternational Journal of Research in Marketing·DateNov 25, 2024
A new study shows that mailing at-home fecal immunochemical testing kits and providing coordinated follow-up led to a tripling of screening completion rates compared to usual care. The intervention increased screening rates by 30% within six months and 34.6% by 12 months.
SourceUniversity of North Carolina Health Care·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateNov 25, 2024
A study estimates that approximately one-third of eligible US adults without diabetes were excluded from clinical trials supporting GLP-1 and GLP-1/GIP medications. The FDA should consider updating labeling to advise caution on generalizing these medications' safety and effectiveness to excluded populations.
SourceJAMA Network·JournalJAMA Internal Medicine·DateNov 25, 2024
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers at European XFEL and DESY develop self-chirping method to produce high-power attosecond hard X-ray pulses without reducing electron bunch charge. This enables non-destructive measurements at the atomic level and opens new avenues for studying matter at the atomic scale.
SourceDeutsches Elektronen-Synchrotron DESY·JournalNature Photonics·TypeExperimental study·DateNov 25, 2024
A study has identified a gene called MdTCP11 that controls the growth of compact apple trees, also known as spur-type varieties. These trees exhibit increased fruit yield and require less pruning, making them ideal for modern orchards.
SourceBoyce Thompson Institute·JournalNature Communications·TypeExperimental study·DateNov 25, 2024
A new study suggests that high-quality friendships formed through social networking can contribute to improved self-esteem, leading to reduced levels of loneliness. The research found that young adults who felt connected with others on social media experienced increased self-esteem, which in turn reduced feelings of loneliness.
SourceUniversity of Arkansas·JournalTelematics and Informatics·TypeSurvey·DateNov 25, 2024
Women who experience severe maternal morbidity in their first birth are less likely to have a subsequent birth. Enhancing antenatal care and reproductive counseling are crucial for women with this history.
Research from the University of Kansas found that suburban school districts are becoming more diverse, while urban districts are experiencing increased racial isolation. This study analyzed census data and geographic mapping technology to compare demographic changes in schools across the country.
SourceUniversity of Kansas·JournalAERA Open·TypeData/statistical analysis·DateNov 25, 2024
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers in Lithuania have developed Forest 4.0, a smart forest data processing model that enables real-time monitoring of forest conditions, sustainable resource accounting, and transparent governance. The system uses IoT sensors and AI algorithms to detect tree diseases, illegal logging, and predict changes in forest ecosystems.
SourceKaunas University of Technology·JournalFrontiers in Forests and Global Change·DateNov 25, 2024
A new paper reveals widespread transnational human rights violations (THRVs) due to repressive states' intensifying tactics. The authors urge the establishment of 'Transnational Rights Protection Offices' to provide support and guidance for individuals affected by these actions.
SourceLancaster University·JournalJournal of Human Rights Practice·DateNov 25, 2024
New measures of neighborhood socioeconomic factors provide critical tools for studying social determinants of health in spinal cord injury research. The findings highlight the importance of understanding how environment influences health and recovery after spinal cord injury.
SourceKessler Foundation·JournalArchives of Physical Medicine and Rehabilitation·DateNov 25, 2024
Researchers at Flinders University advocate for a formal process to acknowledge the valuable contributions of those with lived experience in healthcare research. The study highlights the importance of recognizing their value and increasing visibility, with over 70% of contributors wanting public recognition.
SourceFlinders University·JournalPatient Education and Counseling·TypeSurvey·DateNov 25, 2024
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A study of 129 healthcare professionals in Israel following the 2023 terror attack found high levels of burnout and low well-being among primary care clinicians treating traumatized evacuees. The researchers emphasized the critical importance of prioritizing healthcare personnel's mental health to ensure quality care for trauma survivors.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 25, 2024
The HumanTech Summit 2024 conference brings together experts in technological and social innovation, discussing key topics such as data security and interpersonal relationships. With a proven legacy of impact, the event has attracted over 1,400 participants and featured renowned keynote speakers from top universities.
A new study found that 5% of Canadian respondents skipped or reduced dosages due to cost-related issues. The research highlights the burden of prescription costs on vulnerable populations, including females, bisexual, and Indigenous individuals. The authors suggest that national pharmacare plans can help address these disparities.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·TypeData/statistical analysis·DateNov 25, 2024
Scientists have clarified the conditions under which large numbers of 'squishy' grains, similar to those found in biological tissues, undergo a yielding transition from solid-like to fluid-like behavior. The findings provide insights into the roles of mechanical and biochemical processes in biological systems.
SourceSchool of Science, The University of Tokyo·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateNov 25, 2024
A new IHME study reveals significant progress in the global fight against HIV/AIDS, with sub-Saharan Africa leading the way in cutting new HIV infections and deaths. However, the world is not on track to meet UNAIDS 2030 targets, with a quarter of people living with HIV not receiving treatment.
SourceInstitute for Health Metrics and Evaluation·JournalThe Lancet·DateNov 25, 2024
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
The Gustave Roussy Prize recognizes scientists whose work improves cancer treatment and patient outcomes. Established by Pierre Fabre Laboratories, the €200,000 award aims to push boundaries of oncology and offer personalized treatments.
SourceComprehensive Cancer Centre Gustave Roussy·DateNov 25, 2024
A new model has combined data from unmanned aerial vehicles and Beidou sounding systems to improve typhoon forecasting capabilities. The results show that the forecast landing point of Typhoon Haikui was significantly closer to reality.
SourceInstitute of Atmospheric Physics, Chinese Academy of Sciences·JournalAtmospheric and Oceanic Science Letters·DateNov 25, 2024
A study by the University of Texas at Austin found that most US states with food-waste laws have failed to reduce landfill disposal, except for Massachusetts, which saw a 7.3% decrease in waste. The researchers attribute Massachusetts' success to strong infrastructure and enforcement.
SourceUniversity of Texas at Austin·JournalScience·DateNov 25, 2024
A long-term study found that warmer winters driven by climate change reduce the number of offspring raised annually by the federally threatened Florida scrub-jay by 25% since 1981. This is due to snakes becoming a primary nest predator in warmer weather, leading to increased reproductive effort but lower success rates.
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A recent review paper suggests that cannabis affects the endocannabinoid system in various ways, influencing attention, hyperactivity, and anxiety in individuals with ADHD. However, the picture is complicated by the complexity of cannabis products and legal restrictions on marijuana use.
SourceThomas Jefferson University·JournalDevelopmental Psychobiology·DateNov 25, 2024
A team of researchers at Nagoya University has developed a way to make LEDs brighter while maintaining their efficiency. By tilting the InGaN layers and cutting the wafer into different orientations, they have found that LEDs with lower polarization but in the same direction as standard LEDs show greater efficiency at higher power.
SourceNagoya University·JournalLaser & Photonics Review·DateNov 25, 2024
China's carbon mitigation strategies aim to reduce deaths and diseases related to air pollution, such as PM2.5 and ozone, and mitigate climate-related health impacts.
SourceHealth Data Science·JournalHealth Data Science·DateNov 25, 2024
A study found that mindfulness training tailored to cancer patients' needs improved psychological well-being and self-confidence for advance care planning. For caregivers, it supported improvements in quality of life at follow-up. Mindfulness practices helped individuals address emotional barriers to advance care planning.
SourceRegenstrief Institute·JournalBMC Palliative Care·DateNov 25, 2024
A survey of Oregon's Medicaid and Medicare beneficiaries found that housing and food insecurity rose sharply during the pandemic, despite a significant increase in spending. The study suggests that addressing social needs during healthcare visits can improve health outcomes and reduce costs for taxpayers.
SourceOregon Health & Science University·JournalThe Annals of Family Medicine·TypeSurvey·DateNov 25, 2024
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A new project at the University of Kansas aims to examine medical ableism and its effects on health outcomes among people with disabilities. The study will gather information directly from individuals with disabilities through the National Survey on Health and Disability.
A novel physical reservoir computing device uses a dye-sensitized solar cell to mimic human synaptic elements, enabling efficient time-series data processing and low power consumption. The device achieved high computational performance in tasks such as human motion classification with over 90% accuracy.
SourceTokyo University of Science·JournalACS Applied Materials & Interfaces·TypeExperimental study·DateNov 25, 2024
A team of researchers from the LARS-IIAMA group used satellite technology to detect methane emissions in the palm oil industry in Indonesia, Malaysia, and Colombia. The study confirms that palm oil processing is a significant source of methane emissions, mainly due to anaerobic ponds.
SourceUniversitat Politècnica de València·JournalEnvironmental Research Letters·TypeMeta-analysis·DateNov 25, 2024
A study by researchers at the University of Pennsylvania School of Medicine found that online health care reviews on Yelp have not fully recovered from the COVID-19 pandemic. The analysis shows a significant decline in positive reviews, particularly among rural facilities and those serving areas with higher proportions of Black or Hisp...
SourceUniversity of Pennsylvania School of Medicine·JournalJAMA Network Open·TypeData/statistical analysis·DateNov 25, 2024
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
Scientists at IOCB Prague have developed a new compound that securely binds metal elements, known as lanthanides, inside molecules of medical drugs. This breakthrough discovery, called 'ClickZip', improves diagnostics and accelerates drug development by making pharmaceuticals more stable.
SourceInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague)·JournalNature Communications·TypeExperimental study·DateNov 25, 2024
A study found that people's eyes are drawn to areas with high potential for change before any movement occurs, even when the scene appears static. This behavior is not limited to animate objects and has significant implications for intelligent machines.
SourceTechnische Universität Berlin – Science of Intelligence·JournalPsychological Science·DateNov 25, 2024
Researchers constructed the first complete proton energy spectrum observed during a solar event in Martian space, providing critical data for radiation protection in future Mars missions. The study successfully calculated the radiation dose caused by the event and validated the accuracy of the Tianwen-1 MEPA data.
SourceChinese Academy of Sciences Headquarters·JournalGeophysical Research Letters·DateNov 25, 2024
A team of biologists and mathematicians from the University of Oxford and Manchester have solved the mystery of the squirting cucumber's explosive seed dispersal. The study used a combination of experiments, high-speed videography, image analysis, and mathematical modeling to reveal the key components of the plant's dispersal strategy.
SourceUniversity of Oxford·JournalProceedings of the National Academy of Sciences·DateNov 25, 2024
Researchers create novel protein-based gel, Q5, for high-performance skincare products with improved pH stability and sustainability. The protein-based material enables more stable and responsive formulations under acidic skin conditions.
SourceNYU Tandon School of Engineering·JournalACS Applied Polymer Materials·TypeExperimental study·DateNov 25, 2024
Researchers introduce a new tool called 'persistence images' that uncovers hidden biases in medical imaging data, advancing fairness in healthcare AI. The technology helps detect bias, filter out noise, and improve overall accuracy, leading to more reliable diagnoses and better patient outcomes.
SourceImpact Journals LLC·JournalOncotarget·TypeCommentary/editorial·DateNov 25, 2024
Researchers found that people underestimates the significance of future life events, such as Thanksgiving holidays and career choices. A three-year study aims to understand why this occurs and provide ideas for improvement.
Researchers evaluated over 400 patients with suspected Alzheimer's disease and found that CSF analysis was less reliable than PET imaging. The study suggests using amyloid PET scans as the diagnostic method of choice, especially for those with gray area results between 5.5-7.1 in their CSF.
SourceLudwig-Maximilians-Universität München·JournalAlzheimer s & Dementia·DateNov 25, 2024
Researchers at Vanderbilt University have found that the hunger hormone leptin can direct neural development in a leptin receptor-independent manner. This discovery suggests a novel role for leptin in specifying the development of neural circuits involved in autonomic regulation and food intake.
SourceVanderbilt University·JournalProceedings of the National Academy of Sciences·DateNov 25, 2024
Researchers have found that wood ants can reduce plant diseases like scab and apple rot by up to 50% due to the presence of internal antibiotic substances. The AntFarm project aims to cultivate wood ants on a large scale for relocation in organic apple orchards, offering a sustainable alternative to chemical pesticides.
SourceAarhus University·JournalMicrobial Ecology·TypeExperimental study·DateNov 25, 2024
A large-scale analysis found that cancer immunotherapies are equally effective for both Black and white patients, with Black patients experiencing a lower risk of severe side effects. The study looked at data from over 26,000 patients treated with immune checkpoint inhibitors through the Veteran Health Administration.
SourceMichigan Medicine - University of Michigan·JournalThe Lancet Oncology·TypeMeta-analysis·DateNov 25, 2024
Researchers developed a new framework to understand the complex relationship between wealth and biodiversity, offering communities with limited resources tools to promote biodiversity. The POSE framework examines power, objectives, socio-ecological context, and effort to influence biodiversity.
SourceNorth Carolina State University·JournalEcosystems·DateNov 25, 2024
Researchers at Durham University have made a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. The study reveals unprecedented detail of the enzyme's action on DNA, potentially opening doors for new antibiotic therapies against resistant bacteria.
SourceDurham University·JournalProceedings of the National Academy of Sciences·DateNov 25, 2024
Researchers found pandrug-resistant Klebsiella pneumoniae in Ukrainian war victims, showing high virulence and rapid spread. The bacteria's ability to cause disease remains despite antibiotic resistance.
SourceLund University·JournalJournal of Infection·DateNov 25, 2024
Researchers at Weill Cornell Medicine discovered that keeping the nucleolus small can delay aging in yeast cells. This finding could lead to new longevity treatments and may also reveal a mortality timer that determines how long a cell has left before it dies.
SourceWeill Cornell Medicine·JournalNature Aging·DateNov 25, 2024
Researchers analyzed ceramic fragments of husking trays to identify their use as specialized containers for baking cereal-based doughs. The study provides clear evidence regarding the uses of these artifacts and the nature of the foods processed in them.
SourceUniversitat Autonoma de Barcelona·JournalScientific Reports·TypeExperimental study·DateNov 25, 2024
A recent study found that levothyroxine use is associated with greater loss of total body bone mass and density, even in participants with normal TSH levels. The research suggests that adults taking levothyroxine should discuss their treatment with their healthcare provider and regularly monitor their thyroid function tests.
SourceRadiological Society of North America·DateNov 25, 2024
A team of scientists has pinpointed a critical neural circuit for female sexual rejection, revealing how the brain integrates signals to shape behavior. The ventromedial hypothalamus, specifically progesterone-sensitive neurons in the anterior VMH, play a crucial role in determining whether a female accepts or rejects mating attempts.
SourceChampalimaud Centre for the Unknown·JournalNeuron·TypeExperimental study·DateNov 25, 2024
Researchers have discovered the RGL2 gene's role in regulating rice grain length through cell proliferation, providing new genetic resources for improving yield. The study found that overexpressing RGL2 increased grain length and single-plant yield by promoting cell growth, offering a promising strategy for molecular design breeding.
SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalPhysiologia Plantarum·DateNov 25, 2024
Researchers identify a quantum mechanism as key to accelerating ocean temperatures, which current climate models fail to predict. The study proposes a new paradigm that factors in non-thermal energy, suggesting a revised approach to understanding ocean thermal stability and climate change.
SourceUniversity of Technology Sydney·JournalJournal of Physics Communications·TypeExperimental study·DateNov 25, 2024
A new study finds that replacing meat and dairy products with plant-based foods leads to a 92% reduction in hot flashes in postmenopausal women. The study also shows weight loss in both healthy and unhealthy plant-based diets, suggesting even 'unhealthy' plant-based foods can be beneficial.
SourcePhysicians Committee for Responsible Medicine·JournalBMC Women s Health·TypeRandomized controlled/clinical trial·DateNov 25, 2024
Researchers developed a novel approach to deliver therapeutics into the brain, overcoming the blood-brain barrier. The BCC platform successfully reduced harmful gene activity in models of ALS and Alzheimer's disease, offering new possibilities for treating neurological and psychiatric diseases.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature Biotechnology·TypeExperimental study·DateNov 25, 2024
The report highlights the importance of addressing the rising incidence of cognitive impairment as the population ages, particularly with new treatments for early Alzheimer's disease now available. Developing cognitive care plans, especially for vulnerable populations, is crucial to improve patient outcomes.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 25, 2024
The H.E.S.S. collaboration has detected the most energetic cosmic-ray electrons and positrons ever observed, with energies up to 40 TeV. This discovery provides new insights into the origin of these particles, suggesting they originate from a few sources in our solar system's vicinity.
Scientists have created a method to recover and reuse quantum dots used in microscopic lasers, enabling the sustainable management of these valuable materials. The new recycling technique has been successfully tested on defective samples, resulting in the recovery of 85% of the quantum dots with minimal loss.
SourceOptica·JournalOptical Materials Express·DateNov 25, 2024
A recent study found that Viking colonizers of the Faroe Islands and Iceland came from different Scandinavian populations. The researchers analyzed genetic samples from 139 men and compared them to samples from Norway, Sweden, Denmark, Iceland, and Ireland, revealing a 'founder effect' that persists in today's male populations.
SourceFrontiers·JournalFrontiers in Genetics·TypeExperimental study·DateNov 25, 2024
Children's Hospital of Philadelphia researchers discovered a gene signature that identifies patients with T-ALL at high risk of relapse. The study found a potential therapeutic treatment, venetoclax, which targets specific cells associated with poor outcomes.
SourceChildren's Hospital of Philadelphia·JournalNature Cancer·TypeExperimental study·DateNov 25, 2024
The MIT team fabricated a simple water filter modeled after the mobula ray's plankton-filtering features and studied its performance. They found that the ray's filtering features are broadly similar to industrial cross-flow filters, which could inform design of water treatment systems.
SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateNov 25, 2024
A new study has found that tamoxifen works better for some people due to their unique gut microbiota. Researchers discovered a specific enzyme, beta-glucuronidase, in certain bacteria that helps recycle the drug into its effective form. This finding may lead to tailored treatment interventions for breast cancer patients.
SourceAmerican Society for Microbiology·JournalmBio·DateNov 25, 2024
Researchers confirm oil presence in Mauritius mangrove forest close to Ramsar conservation sites, three years after MV Wakashio spill. The oil has undergone weathering and biodegradation, but its ongoing presence poses an unknown risk to the sensitive ecosystem.
SourceCurtin University·JournalMarine Pollution Bulletin·TypeObservational study·DateNov 25, 2024
Researchers have achieved the first seamless 2D spintronics device made entirely from proximitized structures. A two-dimensional graphene spin valve is enabled by proximity to van der Waals magnet Cr2Ge26, demonstrating the feasibility of using the proximity effect to build essential electronic devices.
SourceElhuyar Fundazioa·JournalNature Electronics·DateNov 25, 2024
Leila Nabulsi is expanding her research program to pinpoint brain pathways affected by bipolar disorder. She will leverage the ENIGMA consortium and advanced statistical methods to build a database of brain changes, potentially improving diagnosis and treatment.
The team used Frontier to conduct a 1,000-fold larger simulation than any previous one, calculating over 2 million correlated electrons. This achievement sets a new benchmark for exascale supercomputing and provides a blueprint for enhancing algorithms to tackle larger scientific problems.
A study of 259 adult patients found that many general practitioners prescribe antibiotics despite negative chest X-rays, highlighting a gap between guidelines and practice. The study aimed to explore the relationship between chest radiography results and antibiotic initiation in community-acquired pneumonia management.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 25, 2024