About The Study: In participants with obesity or overweight, withdrawing tirzepatide led to substantial regain of lost weight, whereas continued treatment maintained and augmented initial weight reduction in this randomized clinical trial that included 670 adults.
Authors: Louis J. Aronne, M.D., of Weill Cornell Medicine in New York, is the corresponding author.
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(doi:10.1001/jama.2023.24945)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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