Can the tailoring of drug dosage improve the effectiveness of radiopharmaceutical therapy (RPT) for cancer patients? The Journal of Nuclear Medicine has issued a new supplement addressing both the rapid progress and the challenges in applying patient-specific radiation dosimetry to guide RPT.
Although patient-specific dosimetry has been used in the past for RPT with good results, it may not be necessary or effective for all radiopharmaceuticals. However, with new nuclear medicine therapies approved or under review by the U.S. Food and Drug Administration and achieving pass-through status with the Centers for Medicare and Medicaid Services, further discussion is warranted. When does dosimetry improve outcomes? How can it be accommodated in current practice? What commercial tools are available? How about reimbursement?
“The time to hesitate is through—there is much to do,” said supplement guest editors Richard L. Wahl, MD, and John Sunderland, PhD. “We are hopeful these articles will provide a useful starting point and review for sites considering implementing dosimetry in their clinical practice or research operations. There is great interest and opportunity.”
Articles in the supplement include:
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The JNM Dosimetry Supplement is available at https://jnm.snmjournals.org/content/62/Supplement_3 .
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About JNM and the Society of Nuclear Medicine and Molecular Imaging
The Journal of Nuclear Medicine (JNM) is the world’s leading nuclear medicine, molecular imaging and theranostics journal, accessed more than 11 million times each year by practitioners around the globe, providing them with the information they need to advance this rapidly expanding field. Current and past issues of The Journal of Nuclear Medicine can be found online at http://jnm.snmjournals.org .
JNM is published by the Society of Nuclear Medicine and Molecular Imaging (SNMMI), an international scientific and medical organization dedicated to advancing nuclear medicine and molecular imaging—precision medicine that allows diagnosis and treatment to be tailored to individual patients in order to achieve the best possible outcomes. For more information, visit www.snmmi.org .
Journal of Nuclear Medicine