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Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, inclu

07.06.23 | PLOS

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Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, inclu
A group of Jamaican fruit bats (Artibeus jamaicensis), which are a natural host of bat-derived Influenza A viruses. Credit: Professor Tony Schountz, Colorado State University (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)

Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, including humans

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In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology : http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002182

Article Title: Evolutionarily conserved amino acids in MHC-II mediate bat influenza A virus entry into human cells

Author Countries : Germany, Thailand, the Netherlands, United Kingdom

Funding: see manuscript

PLOS Biology

10.1371/journal.pbio.3002182

Competing interests: The authors have declared that no competing interests exist.

Keywords

Human Biology Influenza Viruses Viral Entry Viral Infections

Article Information

Journal
PLOS Biology
DOI
10.1371/journal.pbio.3002182
COI Statement
Competing interests: The authors have declared that no competing interests exist.

Contact Information

Claire Turner
PLOS
biologypress@plos.org

How to Cite This Article

APA:
PLOS. (2023, July 6). Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, inclu. Brightsurf News. https://www.brightsurf.com/news/8OM09GQ1/bat-influenza-a-viruses-use-mhc-ii-for-cell-entry-this-study-shows-that-highly-conserved-amino-acids-within-mhc-ii-are-key-for-infection-and-provide-an-explanation-for-the-ability-of-these-viruses-to.html
MLA:
"Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, inclu." Brightsurf News, Jul. 6 2023, https://www.brightsurf.com/news/8OM09GQ1/bat-influenza-a-viruses-use-mhc-ii-for-cell-entry-this-study-shows-that-highly-conserved-amino-acids-within-mhc-ii-are-key-for-infection-and-provide-an-explanation-for-the-ability-of-these-viruses-to.html.