About The Study: In patients presenting to endovascular treatment (EVT)-capable centers 4.5 to 24 hours after stroke onset with proximal middle cerebral artery occlusion, intravenous tenecteplase before EVT did not improve clinical outcomes vs EVT alone.
Corresponding Authors: To contact the corresponding authors, email Yongjun Wang, MD, ( yongjunwang@ncrcnd.org.cn ) and Yunyun Xiong, MD, PhD, ( xiongyunyun@bjtth.org ).
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2026.4292)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Media advisory: This study is being presented at the European Stroke Organisation Conference.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2026.4292?guestAccessKey=55e90ce1-5126-451b-9c02-eff8cd69b8b3&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050826
JAMA