Intravenous Injections
Articles tagged with Intravenous Injections
Intravenous tenecteplase prior to endovascular treatment for ischemic stroke at 4.5 to 24 hours
Ketamine infusions and rapid reduction of suicidal and depressive symptoms in major depressive episode
A systematic review and meta-analysis found single and repeated intravenous ketamine infusions to be efficacious in reducing suicidal and depressive symptoms in acute major depressive episodes. Longer-term outcomes remain unclear.
Injectable therapy could prevent heart failure after a heart attack
Scientists developed an injectable therapy that protects the heart from damage after a heart attack by blocking the interaction between two proteins, Keap1 and Nrf2. The study showed decreased inflammation, cell death, and improved cardiac function in animal models.
Intravenous ferric carboxymaltose in heart failure with iron deficiency
Ferric carboxymaltose did not significantly reduce time to first heart failure hospitalization or cardiovascular death in patients with heart failure and iron deficiency. The treatment also did not reduce total number of heart failure hospitalizations compared to placebo.
Self-destructing vaccine offers enhanced protection against tuberculosis in monkeys
A new self-destructing vaccine provides improved safety and protection against TB in macaque monkeys, outperforming the standard BCG vaccine. The 'kill switch' mechanism eliminates the risk of accidental infection, offering a safer vaccination option for immunocompromised individuals.
Wearable cameras allow AI to detect medication errors
A team of researchers developed a wearable camera system that uses artificial intelligence to detect potential medication delivery errors. The AI achieved high sensitivity and specificity in identifying vial-swap errors, making it a critical safeguard in operating rooms, intensive-care units, and emergency-medicine settings.
New study in JNCCN supports chemotherapy option that reduces side effects for people with gastrointestinal cancers
Researchers found that omitting the bolus-specific 5-fluorouracil (5-FU) portion from common chemotherapy regimens improves tolerability without sacrificing treatment effectiveness. The study of 11,765 patients shows no decrease in overall survival but a notable reduction in cytopenias.
UofL cardiologist leading clinical trial for high potential new stem cell therapy for heart failure
A UofL cardiologist is leading a Phase II clinical trial of a new stem cell therapy for heart failure, the first in the US to use intravenous delivery. The trial aims to determine whether one or multiple doses of mesenchymal stem cells improve health and quality of life for patients.
Time to treatment with intravenous thrombolysis before thrombectomy and functional outcomes in acute ischemic stroke
Intravenous thrombolysis (IVT) plus thrombectomy demonstrates significant benefits over thrombectomy alone when administered within a short timeframe after symptom onset. This study, based on individual participant data from six randomized clinical trials, found IVT before thrombectomy to be time-dependent and statistically significant.
Active components of ginkgo biloba may improve early cognitive recovery after stroke
A study published at the American Stroke Association's International Stroke Conference 2024 found that treating people with ischemic stroke with intravenous injections of a combination of biologically active components of ginkgo biloba during the first two weeks after the stroke improved early cognitive recovery. The treatment, called ...
Insights from a phase II clinical trial with CL2020 Muse cell-based therapeutic for Amyotrophic lateral sclerosis
A phase II clinical trial found Muse cell-based product CL2020 to be highly tolerated and improved ALS symptoms, but may not halt disease progression. The treatment's efficacy depends on combining it with other drugs for future treatments.
An intravenous needle that irreversibly softens via body temperature on insertion
Researchers developed a new intravenous needle that softens via body temperature on insertion, reducing tissue damage and blood-borne disease risks. The P-CARE needle's variable stiffness characteristics make it flexible upon insertion, allowing for more comfortable injections.
New research may make future design of nanotechnology safer with fewer side effects
Researchers developed a promising strategy to reduce adverse reactions to nanoparticles by using complement inhibitors. The study showed that regulators being studied effectively inhibited complement activation by nanoparticles in human serum in vitro and animal models.
Journal of Clinical Immunology publishes Octapharma USA research on cutaquig® evaluating PI treatment options
A recent study published in the Journal of Clinical Immunology suggests that cutaquig infusions at higher infusion rates and volumes are well-tolerated and effective, with reduced infusion time, fewer injection sites, and improved compliance. The study results will be presented at the Clinical Immunology Society 2023 Annual Meeting.
New study using novel approach for glioblastoma treatment shows promising results, extending survival
Researchers developed a novel combination therapy that eradicates tumors in select patients, with prolonged survival rates. The therapy has shown promise in treating glioblastoma, a notoriously difficult-to-treat primary brain cancer.
Octapharma USA research at AAAAI: cutaquig® study at higher infusion rates presented
A new cutaquig study found that increasing infusion volume per site resulted in a reduction of injection sites, while increasing infusion rates decreased infusion duration. The research also showed that dosing every other week demonstrated equivalency to trough levels with weekly dosing.
Small study shows promise for antimalarial monoclonal antibody to prevent malaria
Researchers at the University of Maryland School of Medicine found that monoclonal antibody CIS43LS provided high levels of protection against controlled human malaria infection. The study's findings suggest that this treatment could be a potential game changer for deploying monoclonal antibody therapies in African countries.
Nanoparticles can improve stroke recovery by enhancing brain stimulation, study shows
Researchers from Xi'an Jiaotong-Liverpool University found that brain stimulation combined with a nose spray containing nanoparticles can improve recovery after ischemic stroke. The treatment increased cognitive and motor functions, and weighed more quickly than those treated with TMS alone.
Enabling safe delivery of RNA drugs to the lungs
Researchers at Hokkaido University created a lipid polymer that can carry genetic code into lung cells, potentially treating diseases such as acute respiratory distress syndrome and lung cancers. The delivery method bypasses the liver and targets specific lung cells without targeting ligands.