About The Study: The findings of this systematic review and meta-analysis suggest that single and repeated intravenous ketamine infusions are efficacious in reducing suicidal and depressive symptoms in patients with a major depressive episode in the acute phase, while longer-term outcomes are not well established.
Corresponding Author: To contact the corresponding author, Taeho Greg Rhee, PhD, email tgrhee.research@gmail.com .
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(10.1001/jamapsychiatry.2026.0612)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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JAMA Psychiatry