About The Study: In patients presenting at thrombectomy-capable stroke centers, the benefit associated with intravenous thrombolysis (IVT) plus thrombectomy versus thrombectomy alone was time dependent and statistically significant only if the time from symptom onset to expected administration of IVT was short in this individual participant data meta-analysis (n = 2,313) of six randomized clinical trials.
Authors: Johannes Kaesmacher, M.D., Ph.D., of the University of Bern in Bern, Switzerland, is the corresponding author.
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(doi:10.1001/jama.2024.0589)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being released to coincide with presentation at the International Stroke Conference 2024.
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