The study registry collected data for 1135 patients enrolled at 60 centres across Canada between 1999 and 2001. More than one-third of the patients had an excellent outcome, and the rates of symptomatic intracranial hemorrhage and orolingual angiodema were low (4.6% and 1.3% retrospectively).
The CASES data indicate that thrombolysis for acute ischemic stroke is a safe and effective therapy in actual practice.
p. 1307 Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study
– M.D. Hill et al
Canadian Medical Association Journal