About The Study: Cryopreserved platelets did not meet the predefined threshold for noninferiority in hemostatic effectiveness at 24 hours after intensive care unit admission. Additional predefined end points consistently indicated diminished hemostatic effectiveness, although prespecified adverse events were comparable.
Corresponding Author: To contact the corresponding author, Michael C. Reade, MBBS, DPhil, email m.reade@uq.edu.au .
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(doi:10.1001/jama.2025.23355)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the Critical Care Reviews Down Under 2025 meeting in Melbourne, Australia.
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