Frederic Geissmann and colleagues find that Langerhans cell accumulation in Langerhans cell histiocytosis results from survival rather than uncontrolled proliferation, and is associated with the expansion of regulatory T cells.
Citation: Citation: Senechal B, Elain G, Jeziorski E, Grondin V, Patey-Mariaud, de Serre N, et al. (2007) Expansion of regulatory T cells in patients with Langerhans cell histiocytosis. PLoS Med 4(8): e253.
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CONTACT:
Frederic Geissmann
Necker Enfantes Malades Institute
INSERM U838
156 rue de Vaugirard
Paris, 75015
France
+33 1 40615650
+33 1 40615499 (fax)
geissman@necker.fr
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