About The Study: The findings of this study suggest the NOTCH3-associated small vessel disease (NOTCH3-SVD) staging system will help to better harmonize NOTCH3-SVD and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) cohort studies and registries; may improve individualized disease counseling, monitoring, and clinical management; and may facilitate patient stratification in clinical trials.
Corresponding Authors: To contact the corresponding authors, email Gido Gravesteijn, MD, PhD ( g.gravesteijn@lumc.nl ) and Saskia A. J. Lesnik Oberstein, MD, PhD ( lesnik@lumc.nl ).
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(doi:10.1001/jamaneurol.2024.4487)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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JAMA Neurology