Highlights
Washington, DC (February 24, 2022) — Acute kidney injury (AKI) is a common complication of COVID-19 and is associated with a higher risk of death. A new study published in CJASN has examined the use of palliative care in patients with COVID-19 and AKI.
Palliative care focuses on providing relief from the symptoms and stress of a serious illness. Unfortunately, patients with AKI often do not receive palliative care, but studies have not analyzed the use of palliative care for hospitalized patients with both AKI and COVID-19.
To investigate, Jennifer S. Scherer, MD (NYU Grossman School of Medicine) and her colleagues conducted a retrospective analysis of New York University Langone Health’s electronic health data of COVID-19 hospitalizations between March 2, 2020 and August 25, 2020. These data pertained to three acute care hospitals located in Manhattan, Brooklyn, and Long Island.
Of 4,276 patients with COVID-19, 1,310 (31%) developed AKI. Among the major findings:
“In this study, we found that, as expected, patients with AKI were seriously ill and had a high mortality rate, but what was not expected was that palliative care was often called later in the hospital course than for those without AKI despite having such a high mortality,” said Dr. Scherer. “There are several clinical explanations for this, however given the high mortality it does suggest that patients and families could have benefited from earlier support from palliative care.”
Dr. Scherer stressed that palliative care supports primary doctors in caring for seriously ill patients by managing emotional and physical symptoms while also assisting in advance care planning. Importantly, it can be incorporated into the care plan of someone who is pursuing curative care and can be helpful in an acute and possibly reversible situation.
An accompanying Patient Voice written by two members of the national patient and policy leadership team for the American Association of Kidney Patients cautions against the generalization or extrapolation of this research.
Study authors include Jennifer S. Scherer, MD, Mari Yingzhi Qian, Megan E. Rau, MD, MPH, Qandeel Soomro, MD, Ryan Sullivan, MPH, Janelle Linton, MPH, Judy Zhong, PhD, Joshua Chodosh, MD, MSHS, and David M. Charytan, MD, MSc.
Disclosures:
D.M. Charytan reports consultancy agreements with Eli Lilly/Boehringer Ingelheim, Janssen (steering committee), PLC medical (clinical events committee), Amgen, Allena Pharmaceuticals (DSMB), AstraZeneca, Fresenius, CSL Behring, Gilead, GSK, Medtronic, Merck, and Novo Nordisk; research funding from Amgen, Gilead, and Novo Norodisk, and Bioporto-clinical trial support and Medtronic-clinical trial support; serving as an Associate Editor of CJASN ; and expert witness fees related to proton pump inhibitors.
J. Chodosh reports consultancy agreements with Gerontological Association of America (GSA) and West Health Foundation, honoraria from GSA and West Health, and serving as a scientific advisor or member of Aging New York Fund (ANYF).
J.S. Scherer reports a one-time consulting with CARA Therapeutics and with Vifor Pharmaceuticals; honoraria from Cara Therapeutics and UpTodate as a peer reviewer; and serving as a scientific advisor or member of Cara Pharmaceuticals.
The remaining authors have nothing to disclose.
The article, titled “Utilization of Palliative Care for Patients with COVID-19 and Acute Kidney Injury during a COVID-19 Surge,” will appear online at http://cjasn.asnjournals.org/ on February 24, 2022, doi: 10.2215/CJN.11030821.
The Patient Voice, titled “COVID-19 and Palliative Care: Observations, Extrapolations, and Cautions,” will appear online at http://cjasn.asnjournals.org/ on February 24, 2022, doi: 10.2215/CJN.01090122.
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Clinical Journal of the American Society of Nephrology
24-Feb-2022