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The emergence of successive SARS-CoV-2 variants of concern during 2020-22 created a need to understand the drivers of such growth

01.30.24 | PLOS

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The emergence of successive SARS-CoV-2 variants of concern during 2020-22 created a need to understand the drivers of such growth
Schematic of the study design and modelling procedure. Typical Ct value data and model fits for 2 representative individuals with different covariates. Credit: Russell TW et al., 2024, PLOS Biology, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)

The emergence of successive SARS-CoV-2 variants of concern during 2020-22 created a need to understand the drivers of such growth; this study uses a Bayesian model to reveal how a set of key covariates (the infecting variant, symptom status, age and number of prior exposures) affect viral kinetics at both individual and population levels

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In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology : http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002463

Article Title: Combined analyses of within-host SARS-CoV-2 viral kinetics and information on past exposures to the virus in a human cohort identifies intrinsic differences of Omicron and Delta variants

Author Countries : United Kingdom

Funding: see manuscript

PLOS Biology

10.1371/journal.pbio.3002463

Computational simulation/modeling

Not applicable

Combined analyses of within-host SARS-CoV-2 viral kinetics and information on past exposures to the virus in a human cohort identifies intrinsic differences of Omicron and Delta variants

Competing Interests: see manuscript

Keywords

Bayesian Inference Biological Models Covid 19 Human Biology Kinetics Sars Cov 2

Article Information

Journal
PLOS Biology
DOI
10.1371/journal.pbio.3002463
Method of Research
Computational simulation/modeling
Subject of Research
Not applicable
Article Title
Combined analyses of within-host SARS-CoV-2 viral kinetics and information on past exposures to the virus in a human cohort identifies intrinsic differences of Omicron and Delta variants
COI Statement
Competing Interests: see manuscript

Contact Information

Claire Turner
PLOS
biologypress@plos.org

How to Cite This Article

APA:
PLOS. (2024, January 30). The emergence of successive SARS-CoV-2 variants of concern during 2020-22 created a need to understand the drivers of such growth. Brightsurf News. https://www.brightsurf.com/news/L7VW3XN8/the-emergence-of-successive-sars-cov-2-variants-of-concern-during-2020-22-created-a-need-to-understand-the-drivers-of-such-growth.html
MLA:
"The emergence of successive SARS-CoV-2 variants of concern during 2020-22 created a need to understand the drivers of such growth." Brightsurf News, Jan. 30 2024, https://www.brightsurf.com/news/L7VW3XN8/the-emergence-of-successive-sars-cov-2-variants-of-concern-during-2020-22-created-a-need-to-understand-the-drivers-of-such-growth.html.