Gut-Brain Nexus: The Link Between Gut Microbiota and Neurodegenerative Diseases
Could the microorganisms in our gut hold important clues to brain health?
Growing evidence points to a powerful connection between the gut and the brain. Through the complex, bidirectional gut-brain axis , the gut microbiota can influence metabolism, immunity and brain function, while disturbances in this communication network are increasingly being investigated in relation to neurodegenerative disease.
The Gut-Brain Nexus: The Link Between Gut Microbiota and Neurodegenerative Diseases brings together current scientific evidence and clinical perspectives to explore this emerging field. The book examines how the gut microbiota may influence neurological health and discusses mechanisms through which changes in the microbiome may contribute to disease onset and progression.
The chapters explore the gut microbiota in Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis , as well as irritable bowel syndrome within the broader context of the gut-brain axis. The book also examines potential microbiota-based interventions, including probiotics, prebiotics, synbiotics, dietary and lifestyle approaches and commercially available products.
By bringing together disease mechanisms, therapeutic strategies, current challenges and future directions, the book provides readers with a focused understanding of the growing scientific interest in microbiome modulation and its potential relevance to neurological health.
Key Highlights
About the Editors
Dr. Ajay Kumar is Professor and Head at Sardar Patel College of Pharmacy, Gorakhpur, India. He holds an M. Pharm. in Pharmacology from the Indian Institute of Technology (BHU), Varanasi, and a Ph.D. in Pharmacology & Toxicology from CSIR-CIMAP, Lucknow. His research expertise includes molecular pharmacology, toxicology, genotoxicity and antimicrobial research. He has authored more than 50 research publications, 25 book chapters and 45 conference articles and holds 8 granted patents.
Dr. Avinash Kumar is Associate Professor in the Department of Pharmaceutics at Sardar Patel College of Pharmacy, Gorakhpur, India. His research interests include pharmaceutics, pharmaceutical biotechnology, nanotechnology-based drug delivery systems, biomaterials and advanced therapeutic formulations. His doctoral research, conducted through a joint Ph.D. program involving the Academy of Scientific and Innovative Research and RMIT University, provided interdisciplinary and international research experience.
The Gut-Brain Nexus is intended for researchers, healthcare professionals and general readers interested in the evolving relationship between the microbiome, gut-brain axis and neurological health.
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DOI: 10.2174/97988988162161260101