About The Study: Depression in prior generations was associated with lower cognitive performance in offspring, whether assessed by family history or genetic data. There are opportunities to generate hypotheses about how this arises through genetic and environmental determinants, moderators of brain development and brain aging, and potentially modifiable social and lifestyle factors across the life span.
Authors: Breda Cullen, Ph.D., of the University of Glasgow in Glasgow, United Kingdom, is the corresponding author.
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(10.1001/jamapsychiatry.2023.0716)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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JAMA Psychiatry