The vaginal microbiota is shaped by bacterial access to specific nutritional resources, influencing health outcomes. This study uses a resource-based model supported by clinical data to identify key ecological mechanisms underlying microbiota composition and potential bacterial vaginosis interventions.
In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology : https://plos.io/4qaZ2kt
Article title: Resource landscape shapes the composition and stability of the human vaginal microbiota
Author countries : France, United States
Funding: Research reported in this publication was supported by the Fondation pour la Recherche Medicale (award SPF202005011951 to TK), the Expos’UM institute (to NT) and also in part by the National Institute for Allergy and Infectious Diseases (awards R01NR015495 to JR) and the National Institute of Nursing Research of the National Institutes of Health under (award UH2AI083264 to JR), the Gates Foundation (award OPP1189205 to JR), and the CUPS2 project from the Agence Nationale de la Recherche (award ANR-22-CE34-0024 to SA). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
PLOS Biology
Computational simulation/modeling
Not applicable
Competing interests: We have read the journal’s policy and the authors of this manuscript have the following competing interests: JR is the cofounder of LUCA Biologics, a biotechnology company focusing on translating microbiome research into live biotherapeutics drugs for women’s health, and a member of Ancilia Bio Scientific Advisory Board. The other authors have declared that no competing interests exist.