About The Study: This study demonstrates that the artificial sweetener neotame was a ubiquitous constituent of popular disposable e-cigarettes sold in the U.S. in 2024, including those containing no nicotine or the nicotine analogue 6-methylnicotine. Neotame is 7,000 to 13,000 times sweeter than table sugar and is 35 to 65 times sweeter than aspartame.
Corresponding Author: To contact the corresponding author, Sven E. Jordt, PhD, email sven.jordt@duke.edu .
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(doi:10.1001/jama.2025.7398)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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