Researchers at Northwestern University have discovered a powerful relief for kids' chronic eczema using diluted beach baths. The study found that giving pediatric patients with moderate or severe eczema reduced signs of infection and improved the severity and extent of the eczema on their bodies.
A BUSM study found that using photographs of UV exposure motivates preteens to adopt better sun protection habits, resulting in a 36% lower reported sunburn rate compared to a control group. The UV photographs also helped identify high-risk students who benefited from the intervention.
Researchers discovered an antioxidant, ellagic acid, which prevents collagen destruction and inflammatory response in human skin cells and mice exposed to UV-B. The study found that ellagic acid reduces MMP secretion and inflammation, demonstrating its potential to prevent wrinkle formation and photo-aging.
A survey found that thinner melanomas are more likely to be detected by physicians, while thicker tumors are often self-detected. Physician skin examination and improved public awareness are key targets for new interventions to promote earlier detection.
A study of 78,061 women found that those with psoriasis were 63% more likely to develop diabetes and 17% more likely to develop hypertension than women without psoriasis. Systemic inflammation in psoriasis may be a biologically plausible explanation for the association.
Researchers found that reducing sugary beverages consumption leads to a decrease in calorie intake in children and teens. An intervention program also showed promise in changing behaviors among Dutch schoolchildren.
A UCSF research team has developed a technique to diagnose melanoma by measuring differences in levels of genetic markers, with a success rate higher than 90 percent. The new strategy distinguished between benign and malignant skin lesions, shedding light on difficult-to-diagnose cases.
CTIP2 is a transcriptional factor controlling skin development and lipid biosynthesis, potentially playing a role in skin disorders and wrinkling. Understanding its mechanisms may provide a solution to these issues.
A new study found that a genetic variation increases melanoma risk in pre-menopausal women, with over 40% of those under 50 carrying the mutation. This discovery could lead to more effective surveillance and prevention strategies for this deadly skin cancer.
A study published in Archives of Dermatology found that wet combing is more accurate than visual inspection for identifying active head lice infestations. The method correctly identified 90.5% of cases, while visual inspection only detected 28.6%. This finding has implications for the diagnosis and management of pediculosis capitis.
Low-dose acitretin therapy shows promise in reducing nail psoriasis symptoms, with 25-33% of patients experiencing complete or near-complete clearing. The treatment also demonstrates safety and effectiveness in improving quality of life for patients suffering from severe nail psoriasis.
Researchers found that high levels of iron cause oxidative stress and lead to the death of cancer cells. The study suggests a novel approach for treating cutaneous T cell lymphoma by selectively releasing iron.
A new study finds that Albolene moisturizing cleanser is as effective as a prescription moisturizer in reducing dryness, scaling, and itching related to mild to moderate eczema. The study suggests that over-the-counter moisturizers can be a cost-effective alternative for treating eczema without a prescription.
Studies show metabolic syndrome and obesity linked to increased risk of cognitive impairment, dementia in both men and women. Research also reveals unique associations between body mass index, weight changes, and dementia risk.
The number of Americans with diabetic retinopathy is projected to triple by 2050, while cataracts will increase by 235% and glaucoma among elderly Hispanic individuals will increase 12-fold. Ophthalmologists must collaborate with other clinicians to help patients control their diabetes before eye complications worsen.
Researchers have developed a potent drug against melanoma by combining compounds from green vegetables with selenium. The new compound, isoselenocyanate, targets the Akt3 protein and reduces tumor growth by 50-60%, showing potential for low-toxicity treatment.
A study found that sun-safe pool policies are associated with improved sun safety behaviors among outdoor staff, leading to fewer reported sunburns. The program also promotes healthy sun protection habits and creates a work environment conducive to developing these habits.
A study of 170 military personnel who were evacuated from combat zones found that 34% were diagnosed with dermatitis or general skin inflammation. The study highlights the importance of identifying individuals with chronic skin conditions before deployment to reduce evacuations and improve combat effectiveness.
Researchers found that ustekinumab significantly improves symptoms of psoriatic arthritis and diminishes skin lesions in patients. The treatment, which targets interleukins 12 and 23, showed good tolerability and a benign safety profile.
A randomized, double-blind study found ustekinumab to be effective in treating moderate-to-severe psoriatic arthritis, with significant improvements in pain and stiffness. The treatment showed sustained benefits up to 36 weeks after initial dosing.
A recent study identified four new DNA 'hotspots' linked to psoriasis, an autoimmune disease that causes scaling and inflammation. The study also confirmed the association of two previously identified sites with psoriasis, revealing potential genetic markers for the disease.
Researchers have discovered DNA hotspots associated with psoriasis, an autoimmune disease characterized by skin patches and joint pain. The study identified four novel genes linked to the condition, providing potential targets for new treatments.
Psoriasis affects 0.6-4.8% of the world's population, impairing financial status and well-being. Online support groups provide valuable resources, anonymity, and improved quality of life for patients. The study found that 49.5% of participants perceived improvements in psoriasis severity since joining an online community.
Patients using a retinoid cream containing tretinoin were more likely to die than those using a placebo in the study. However, evidence does not suggest that the therapy caused the excess deaths, and alternative explanations such as smoking are possible.
A pre-emptive skin regimen can significantly reduce skin-associated toxicities associated with panitumumab for metastatic colorectal cancer treatment. The study found that this approach reduced the incidence of grade 2 or higher skin toxicities by over 50%. Patients who received prophylactic treatment reported improved quality of life,...
Stanford researchers have discovered a connection between two aging pathways, SIRT6 and NF-kB, which could lead to a new understanding of how cells age. The study found that SIRT6 regulates gene expression by modifying histones, making it harder for NF-kB to trigger the expression of genes associated with aging.
Researchers discovered a significant association between psoriasis and high levels of leptin, an obesity-related hormone that contributes to metabolic abnormalities. The study also found that body weight loss can decrease leptin levels and improve insulin sensitivity, potentially reducing the risk of cardiovascular diseases.
A study of over 1,000 female sex workers in Cambodia found that new entrants were twice as likely to have gonorrhoea or chlamydia. The high risk is attributed to limited access to STI services and prevention information. The study highlights the need for improved health education and training programs for sex workers.
Researchers at the University of Rochester Medical Center have identified several compounds that block unwanted RNA coupling, a key step in the disease. The discovery offers hope for developing a drug-like molecule to treat myotonic muscular dystrophy.
A randomized trial found that indigo naturalis ointment significantly improved scaling, erythema, and induration in patients with treatment-resistant psoriasis. After 12 weeks, the treated plaques showed an 81% improvement compared to a 26% improvement for non-medicated ointment-treated lesions.
A study found that beachgoers who intended to tan and used the least amount of sunscreen were at higher risk of skin cancer. The researchers identified three groups with distinct characteristics and sun protection behaviors, highlighting the need for targeted interventions to reduce UV radiation exposure.
Researchers develop a novel designer molecule that targets malignant melanoma cells using two different routes: triggering the immune system to attack and switching off a specific gene, driving cancer cells to suicide. Initial experiments in mouse models show significant inhibition of metastasis growth and tumor shrinkage.
A study comparing results of allergy patch tests between children and adults found that both groups reacted to various allergens at approximately the same rate. However, children were more likely to react to nickel, cobalt, thimerosal, and lanolin, while adults were more likely to react to neomycin, fragrance mix, M. pereirae, and quat...
Researchers found that photodynamic therapy, combining a topical photosensitizer and laser treatment, increases collagen levels and produces other skin changes in sun-damaged skin. The treatment may be particularly effective for skin with severe sun damage.
A study found that low birth weight is a significant risk factor for infantile hemangiomas, with a nine-fold increase for every 1.1-pound decrease in birth weight. The number of low birth weight infants has increased significantly in the US, contributing to an estimated 40% rise in infantile hemangioma incidence over the last 20 years.
A study found laser therapies to be safer when used separately, with more effective leg hair removal. Alexandrite lasers showed long-term efficacy, but caused higher pain severity and hyperpigmentation compared to Nd:YAG lasers.
A study published in Archives of Dermatology found that light-activated therapy increased levels of Ki67, a protein involved in new skin cell growth, and collagen production. Skin thickness also increased after treatment, suggesting improved appearance.
A study found that oral vitamin D supplements increased cathelicidin production in the skin of patients with atopic dermatitis, a common form of eczema. This increase helped to correct a defect in the immune system and reduce the risk of skin infections.
Researchers have found that nanoparticles can pass through human skin, especially when damaged, raising concerns about their safety. The study, led by Dr. Lisa DeLouise, used mice as a model and showed that nanoparticles accumulate in skin folds and around hair follicles.
UC Davis researchers have identified a cellular process promoting inflammation and discovered an important starting point for identifying and testing new drugs. The study found that protein sPLA2-IIA binds to two integrins, causing them to rapidly multiply and boosting an immune response already gone awry due to disease.
Leading researchers call for ban on indoor tanning beds and publicity claiming safety, highlighting increased risk of melanoma and DNA damage from UV exposure. Published data suggest a link between indoor tanning and an increased risk of melanoma, making a 'safe' tan with UV radiation unlikely.
Researchers develop nanoparticles that deliver siRNA to cancer cells, reducing tumor growth and size by up to 70%. Targeting multiple genes simultaneously leads to synergistic effects, offering a promising personalized medicine approach.
Topical estradiol application stimulates collagen production in sun-protected skin of older men and women, but not in sun-exposed areas like the face or arms. This study found that natural aging and photo-aging share biochemical features, including a reduction in collagen, which is essential for maintaining skin's inner layer structure.
Research from Michigan Medicine found that estrogen treatments stimulate collagen production in non-sun damaged skin, but have no effect on sun-damaged skin. The study suggests it's difficult to repair photoaged skin due to altered skin response to topical estrogen treatment.
Scientists have pinpointed the FCER1A gene as a major factor in allergic diseases, influencing IgE antibody production and leading to conditions like hay fever and asthma. The discovery has potential for guiding new drug development.
A 21-year-old amateur bodybuilder suffered from anabolic steroid-induced acne conglobata, leading to deep ulcerations and abscesses. Discontinuing steroid use improved skin lesions, but extensive scarring is expected to remain lifelong.
Researchers at Monell Chemical Senses Center have discovered a unique scent associated with basal cell carcinoma, the most common form of skin cancer. By analyzing volatile organic compounds in the air above skin lesions, they found distinct profiles that could potentially be used to screen for and diagnose skin cancers at early stages.
A study of 266 teens with acne found that they would trade significant time and money for freedom from the condition. Teens were willing to pay up to $275 to never have acne, while parents were willing to pay $250 for their child's acne-free life.
Researchers discovered that eosinophils release mitochondrial DNA, binding it to toxic granule proteins to form a net that traps and kills bacteria. This mechanism is linked to improved survival rates and lower bacterial numbers in mice with widespread infections.
Researchers explore new treatments for psoriasis, revealing a potential therapeutic option in AEB071, while cautioning further clinical trials are needed. Additionally, studies uncover the reasons behind gene therapy complications in SCID patients, shedding light on insertional oncogenesis and acquired somatic mutations.
Researchers at NYU Cancer Institute have identified mebendazole as a potential treatment for metastatic melanoma, exploiting its ability to target cancer-causing proteins. By inactivating the protein Bcl-2, mebendazole induces programmed cell death in malignant melanoma cells.
A study published in Archives of Dermatology found that women are more likely to remove their tattoos due to social stigma and embarrassment, with 69% of participants being women. The study also revealed that societal support for women with tattoos is limited, leading to increased dissatisfaction with their tattoos over time.
Researchers have discovered that a natural compound from magnolia cones can block a previously 'undruggable' pathway for cancer growth. This finding could lead to the development of new treatments by making tumors more sensitive to traditional chemotherapy drugs.
Researchers found that UVA1 phototherapy is effective for patients with morphea and related diseases regardless of skin type. The study analyzed over 100 patients and showed no significant correlation between skin type and clinical improvement scores.
Researchers at North Carolina State University found that quantum dots can penetrate rat skin if there is an abrasion, providing insight into potential workplace concerns. The study shows that even minor cuts or scratches could allow these nanoparticles to penetrate deep into the viable dermal layer and potentially reach the bloodstream.
Researchers at UIC have identified a novel function for an enzyme involved in tissue injury in acute respiratory distress syndrome (ARDS). The finding offers new therapeutic targets for lung inflammation and injury prevention.
Researchers found that performing a standardized 60-second hair count is a reliable method for assessing hair shedding in healthy men. The study found consistent results across age groups, with an average loss of 10 hairs per minute, and demonstrated low intrapatient variability.
Researchers at the University of Minnesota have developed a new standard of care for children with recessive dystrophic epidermolysis bullosa (RDEB) using cord blood and bone marrow transplants. The treatment has shown promising results in improving skin quality and reducing blisters, offering new hope for these patients.
Researchers found that topical retinoic acid, carbon dioxide laser resurfacing, and injections of cross-linked hyaluronic acid improve skin's appearance and resistance to bruising by stimulating new collagen production. Collagen collapse is a key factor in skin aging, but fibroblast cells can recover and make more collagen.
Researchers discovered a molecular alarm system in the skin that detects defects and triggers an immune response, leading to potentially harmful effects. The study found that genetic abnormalities in the skin can lead to an overproduction of white blood cells, which can be life-threatening.