Researchers found that a social-skills intervention called Children's Friendship Training can lead to a decrease in hostile attributions or perceptions of children with PAE. The study suggests that such interventions may improve their social skills and relationships, leading to better outcomes.
The Huichol population of Mexico has the highest documented CYP2E1*c2 allele frequency, placing them at high genetic risk for alcoholism and alcoholic liver disease. The absence of protective ADH1B and ALDH2 polymorphisms in this group exacerbates their vulnerability.
A study found a significant association between a polymorphism of the µ-opioid receptor (OPRM1) gene and alcohol misuse among adolescents. The G allele variant was associated with increased sensitivity to the pleasurable effects of alcohol, leading to more frequent drinking and problems.
Researchers identified a cellular pathway by which alcohol promotes cancer progression through the activation of EMT in colon and breast cancer cells. This mechanism may contribute to the increased risk of these cancers associated with alcohol consumption.
Interaction between education and a polymorphism of the reward gene contribute to severe alcoholism among Mexican Americans. Researchers found that individuals with less than or up to 12 years of education are at high risk for severe alcoholism when combined with the OPRM1 A/A genotype.
A new study found that completed and attempted suicides occur at greater rates in rural communities with higher bar densities. Completed suicide rates were lower among blacks and Hispanics, but higher among low-income, older whites living in rural areas.
Research found that IL-1 gene polymorphisms are associated with alcohol dependence in Spanish Caucasian males, particularly those with a certain haplotype. The study suggests a protective effect of this haplotype on better outcomes, highlighting the complex role of genetic factors in AD.
A new study found that people who start drinking at an early age are more likely to develop alcohol dependence. The study suggests that genetic factors play a significant role in the development of AD symptoms, particularly in those who begin drinking before age 15.
A new study found that low-alcohol prices in college bars pose a threat to public health and safety. The research, published in Alcoholism: Clinical & Experimental Research, suggests that cheap drinks lead to higher intoxication levels and related consequences.
A recent study found that excessive drinking can lead to reduced activity in the amygdala and hippocampus, two brain regions responsible for processing facial emotions. This can result in emotional difficulties, such as misperceiving facial cues, emotional flatness, and apathy, which can negatively impact interpersonal relationships.
A recent study found that binge drinkers expend more attentional effort to complete tasks and have difficulties differentiating between relevant and irrelevant information. Young Spanish university students who engaged in binge drinking showed anomalies during a visual working memory task, requiring greater attentional processing.
A study found that testing for blood alcohol levels (BALs) can identify high-risk patients admitted to trauma centers who had denied excessive drinking. Elevated BALs are associated with higher rates of complications and predict the development of delirium treatments.
A study found that HIV infection and chronic alcoholism have a synergistic damaging effect on the brain, particularly impairing immediate episodic memory while preserving working memory. Individuals with both conditions are at risk of trouble learning new information, affecting daily activities and work-related tasks.
A study comparing children with FASD and ADHD reveals significant differences in social cognition and emotional processing. Children with FASD show a distinct profile of weaker social skills, including high distractibility and restlessness, which may underlie the severe conduct problems observed in these individuals.
A new study found that genetic predispositions can be expressed earlier in life through behavioral problems, while environmental influences can modify gene expression. Females may be more susceptible to certain environmental factors, which can encourage or inhibit the expression of genetic traits.
Resveratrol shows therapeutic potential in preventing age-related disorders, including neurodegenerative diseases, inflammation, diabetes, and cardiovascular disease. Low doses improve cell survival, while high doses increase cell death.
A recent study found that frequent extreme heavy drinkers, particularly those with a sensation-seeking disposition, face a heightened risk of alcohol-related injuries. The study analyzed data from over 12,900 college students and discovered a significant correlation between excessive drinking patterns and increased injury rates.
A study found that individuals with a low response to alcohol are at a higher risk for developing alcohol-use disorders across adulthood. The research, published in Alcoholism: Clinical & Experimental Research, suggests that this unique risk factor is not solely related to other factors such as family history or age of onset.
A 24/7 free-access, anonymous, interactive web-based self-help intervention called Drinking Less (DL) can aid problem drinkers in reducing their alcohol consumption. After six months, participants decreased their mean weekly alcohol consumption and 18.8% changed their drinking patterns to 'low-risk drinking'.
Research suggests that individuals with strong negative mood-related drinking motives may be vulnerable to developing both major depression and alcohol dependence. The study found that familial factors contributing to mood-related drinking motives also contribute to the overlapping risk for MD and AD.
A new study identifies Cyber Millenials, affluent, health-conscious young adults living on the urban fringe, as those most likely to engage in high-risk drinking. These individuals, despite being tech-savvy and well-educated, exhibit detrimental binge drinking habits.
Chronic smoking impairs brain blood flow recovery after long-term heavy drinking, according to a new study. Brain perfusion in frontal and parietal cortices improved with abstinence, but smokers showed significantly less recovery, particularly in the frontal lobes.
A mouse study found that genetics play a role in susceptibility and resistance to prenatal alcohol exposure, with some strains showing teratogenic effects while others resisted, suggesting genetic influence. The study also highlights the importance of considering genetic factors in human FASD research.
A study found that adolescent binge drinkers have lower coherence of white matter fibers, suggesting poorer white matter health. This compromise can lead to difficulties in processing information and emotional functioning.
A new study using mice found that genes affect impulsivity, which can contribute to the risk of developing alcoholism. The study suggests that individuals with high impulsivity may be more likely to experiment with drugs and develop a substance-use disorder like alcoholism.
A new study identified four underage drinking laws that lead to reductions in underage drinking-and-driving fatal crashes: possession, purchase, use and lose, and zero tolerance. These laws save an estimated 864 lives each year. Additionally, three general impaired-driving laws were found effective in reducing fatalities.
A new study found that naltrexone significantly decreases heavy drinking rates in smokers enrolled in smoking cessation, with the heaviest drinkers benefiting the most. The medication's potential benefits for co-use of nicotine and alcohol may provide a helpful addition to standard quitting programs.
A study published in Alcoholism: Clinical & Experimental Research found that the brain maintains language skills despite alcohol damage by drawing from other regions. The research used fMRI scans to investigate neural activity in alcoholic and healthy males performing an auditory language task.
A rodent study confirms that low to moderate levels of alcohol increase beta-endorphin release in the midbrain/Ventral Tegmental Area (VTA) region, producing a general feeling of well-being. This supports a role of beta-endorphin in mediating some of the rewarding effects of alcohol.
Research finds that light-to-moderate drinking with high social support reduces the risk of stroke, coronary heart disease, and total cardiovascular disease. Men with higher social support have a more pronounced benefit from moderate alcohol consumption.
New research on the University of Rhode Island Change Assessment Scale (URICA) finds that motivational readiness is more about individual self-reflection than avoiding negative consequences. The study, published in Alcoholism: Clinical & Experimental Research, suggests that motivation and readiness to change are influenced by personal ...
Heavy drinking near off-premise outlets increases gun violence risk, study finds. Reducing outlet density and server training may help reduce gun violence.
A study examining Asian young adults found consistent additive effects of ethnicity and ALDH2 genotype on drinking behaviors. Korean ethnicity and ALDH2 status were associated with significant variance in alcohol consumption, suggesting that genetic influences may play a role in predicting drinking behavior among this population.
A new study found a link between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and risk for post-treatment relapse among alcohol-dependent patients. The findings suggest that genetic markers may be used to predict treatment outcomes and inform personalized therapy approaches.
New rodent findings show that chronic drinking causes more injury to the liver than acute or binge drinking, with persistent gene-expression changes and deleterious conditioning. This research highlights the importance of daily, excessive drinking in programming the liver to become dependent on alcohol.
New rodent findings show that dietary zinc supplements throughout pregnancy can reduce some alcohol-related birth defects. Zinc supplementation also increases the mother's blood zinc to prevent fetal zinc deficiency and subsequent fetal damage.
Researchers developed a composite metric of maternal-drinking measures that can predict prenatal neurobehavioral dysfunction and deficits in children, identifying over 62% of mothers as drinking at risk levels. The metric was more successful than individual measures in predicting poor child cognition and behavior problems.
A recent study used Diffusion Tensor Imaging (DTI) to assess white-matter microstructure in youth with and without histories of heavy prenatal alcohol exposure. The findings show that alcohol can damage the microstructural integrity of fetal cerebral white matter, particularly in the frontal and occipital lobes, which are relevant for ...
Individuals with the ADH1C*1 gene variant produce more acetaldehyde, leading to greater cellular DNA damage and a heightened risk of colorectal cancer. Chronic drinking is also a known risk factor for colorectal cancer.
Research found that drinking and high-activity MAOA can predict the risk of impulsive violence, while aging may decrease this risk. Coaching and psychopharmacological treatment may help control violent behaviors in high-activity MAOA offenders.
Researchers found that men tend to use heavier intoxication words like 'hammered,' while women use more moderate terms like 'tipsy.' This could mislead women about their level of intoxication and driving ability.
A study found that extended-release naltrexone improves mental health, social functioning, general health, and physical functioning in alcohol-dependent patients. The medication reduces drinking and increases quality of life, making it a cost-effective treatment option.
Research suggests that light-to-moderate drinking can promote cytoprotective cellular mechanisms, reducing the risk of cardiovascular disease and cognitive decline. Moderate alcohol exposure has also been shown to activate anti-inflammatory processes and promote neuronal survival pathways.
A new study reveals hazardous drinking among NZ university students begins in high school, with high levels of binge drinking and related problems. The study recommends prioritizing reduction of binge drinking in high school and implementing early identification systems on campuses.
Research finds that specific DNA sequence variations of the serotonin transporter gene can influence drinking intensity among alcohol-dependent individuals. The study analyzed six single nucleotide polymorphisms and found a significant association between one particular variation and lower drinking intensity.
A recent study found that non-beverage alcohols, including medicinal tinctures and eau-de-colognes, are highly concentrated and cheaper than standard Russian vodka. Researchers believe these products pose a significant health risk to consumers, particularly those who rely on them as an affordable source of alcohol.
A new study found a strong link between alcohol outlet density and male-to-female partner violence, with higher risks in neighborhoods with more drinking places. The research used individual and couple-level data to assess the relationship between alcohol availability and intimate partner violence.
A new study reveals that substance abuse disorders (SUDs) and other psychiatric disorders are prevalent among French prisoners. Dual diagnosis (DD), a co-existence of SUD and any Axis I disorder, is a major risk factor for suicide, with mood and anxiety disorders being the most frequent disorders found in DD prisoners.
A new study has found that US Hispanics, belonging to four national groups, prefer beer as their beverage of choice. The study, published in Alcoholism: Clinical & Experimental Research, revealed that beer was the preferred beverage among all Hispanic respondents, with variations in preference across ethnic subgroups.
A new study found that individuals who start drinking before age 15 are more likely to develop alcohol-use disorders (AUDs) in adulthood. The research, published in Alcoholism: Clinical & Experimental Research, controlled for various individual risk factors and found that early drinking is associated with increased AUD risk.