A clinical trial involving over 2,100 participants found that commonly used pain medications such as naproxen and celecoxib did not reduce the incidence of Alzheimer's disease. The study suggests that these medications should not be taken primarily to prevent Alzheimer's disease.
Researchers have created a mouse model of infantile spasms, which closely resembles human cases and responds to current treatments. This model could lead to new treatments for thousands of young children suffering from these catastrophic seizures.
Research found telephone-guided treatment with clot-busting drug tissue plasminogen activator (tPA) to be safe and effective for rural stroke patients. The study, the largest of its kind, showed improved outcomes compared to a large national study published in 1995.
Research found that sleep strengthens memory by protecting and consolidating information, leading to improved recall rates compared to wakefulness without interference. Sleep also helped individuals handle competing information more effectively.
Research found that individuals with moderate to vigorous exercise levels were 40% less likely to develop Parkinson's disease than those with low activity levels. The study of over 143,000 people suggested a potential benefit of regular physical activity in reducing the risk of this debilitating condition.
A community-based study found that women with a lifetime history of migraine performed worse on cognitive tests initially but showed a 17% less decline in performance over time compared to those without migraines. Lifestyle factors such as diet and behavior may play a role in protecting memory.
Researchers have localized two new genes associated with febrile seizures in infancy and childhood, which could improve the understanding, treatment, and prevention of this disorder. The study found that chromosome 3 was shared by all family members who had febrile seizures, while a modifier gene on chromosome 18 may also be involved.
Research finds people with inflammatory bowel disease are at risk for developing nerve damage, including carpal tunnel syndrome and small fiber neuropathy. Women with bowel disease are more likely to develop neurological problems than men.
Researchers found brain structure changes in people who developed dementia or Alzheimer's disease up to four years before memory loss began. Those destined for MCI had lower cognitive test scores at the start of the study, even within normal ranges.
Researchers found that natalizumab significantly reduces vision loss and likelihood of sustained vision loss in patients with relapsing MS. The drug's potential benefits must be weighed against its risks, including progressive multifocal leukoencephalopathy.
A study published in Neurology found that blood pressure rates during periodic leg movements rose significantly in people with untreated RLS, increasing cardiovascular risk. The study also showed that age and disease history are key factors contributing to these increased blood pressure changes.
A study published in Neurology found that retigabine, a new epilepsy drug with a unique mechanism of action, is both safe and effective. In the study, participants who received the highest dose of retigabine experienced an average reduction of 35% in seizure frequency compared to those receiving a placebo.
Researchers found that taking the prolonged release version of ropinirole with levodopa significantly reduced daily 'off' time by 2.1 hours compared to the placebo group. Additionally, those taking ropinirole showed improvements in troublesome Parkinson symptoms, quality of life, and motor function.
Researchers found that up to 36% of people with mild traumatic brain injury suffer from circadian rhythm sleep disorder, which can worsen other symptoms. The study highlights the need for improved diagnosis and treatment of sleep disorders in these patients.
A study of 9,178 people in Denmark found that those with two copies of the H63D genetic defect were twice to three times more likely to develop stroke than those without the gene. The study suggests a link between the H63D gene and increased risk of stroke, but the exact mechanism is unclear.
A study published in Neurology found that family caregivers of people with ALS experienced significant increases in depression and feeling burdened over nine months, while those with the disease showed little change. This highlights the need for interventions to enhance communication between patients and caregivers.
A two-year study found that the drug risedronate reduced hip fractures in people with Parkinson disease by three times compared to placebo. Risedronate also increased bone mineral density and decreased biomarkers for bone loss, effectively controlling osteoporosis progression.
A recent study published in Neurology suggests that men are more likely than women to achieve functional independence after receiving clot-busting drug tissue plasminogen activator (tPA) following a stroke. The study found that despite lower survival rates, men had better outcomes at three months post-treatment.
A study published by the American Academy of Neurology found that weight loss surgery can lead to vitamin B1 deficiency, resulting in memory loss, confusion, and other neurological problems. The syndrome, known as Wernicke encephalopathy, affects the brain and nervous system when the body lacks sufficient thiamine.
Epidural steroid injections provide small but temporary pain relief for lower back pain radiating down a leg. Long-term pain relief beyond three months is not guaranteed.
Researchers found that tooth-brushing can induce seizures in individuals with epilepsy, possibly linked to lesions in the somatosensory area of the brain. The study suggests a potential link between rhythmic stimuli and seizure activity.
A study of 1,040 stroke patients found that 27% had cholesterol levels higher than recommended by national guidelines. Despite this, only 7% were at their ideal level for preventing future strokes and heart disease, emphasizing the importance of regular testing and treatment.
A study of 118 pilots aged 40-69 found that experts demonstrated improved performance over time, outperforming younger pilots in traffic avoidance and scanning cockpit instruments. Pilots with advanced FAA ratings showed the least decline in skills, suggesting a 'crystallized intelligence' mechanism.
A study analyzed provider-reported events and errors in stroke patients, finding 12% experienced an adverse event and 86 were preventable. The hospital implemented new procedures to improve patient safety, including check sheets and safer medication delivery.
A large study of over 27,000 women found that those with high cholesterol were more than twice as likely to suffer a stroke compared to healthy women with lower cholesterol levels. The research suggests that avoiding unfavorable cholesterol levels may help prevent stroke.
A new study published by the American Academy of Neurology found that people with 'benign MS' for 10 years are at risk of disease progression after 20 years. After 20 years, nearly half of those with benign MS had progressed to a point where they needed a cane to walk.
A study published in Neurology found that smoking marijuana reduced nerve pain in people with HIV-associated sensory neuropathy by 34%, compared to 17% for those who received a placebo. The study also showed significant relief from chronic pain, with an average reduction of 72%.
A study by Wei-Jian Jiang found that successful stent placement reduces the risk of stroke for individuals with severe artery blockage. The risk was comparable to those with moderate blockage, suggesting that stents may not be beneficial for all patients at high risk.
A clinical trial found that nearly 600 adults with newly diagnosed epilepsy experienced few to no seizures while taking levetiracetam as a single therapy. The study also showed that patients remained seizure-free for at least six months at the lowest dose level.
A review of nearly 500 articles found nearly one in 1,000 people have multiple sclerosis (MS) and 67 out of 1,000 elderly Americans have Alzheimer’s disease. The study also reported a 50% drop in traumatic brain injuries and updated rates for stroke, Parkinson's disease, and childhood disorders like autism and cerebral palsy.
A study of over 2,300 individuals from 1,000 families found that family members with MS tend to have similar ages at disease onset, but not disease severity. The researchers also discovered no correlation between disease progression and severity among siblings or parents and children.
Researchers found that epilepsy patients can reliably predict when they are likely to have a seizure, with 32% accuracy. Accurate predictions also indicate reduced risk of seizures, providing reassurance and improved quality of life for those with epilepsy.
Researchers found that some dogs are responding to seizures caused by psychological conditions, rather than epilepsy. People with psychogenic seizures need psychiatric evaluation and treatment, not specialized training for epileptic seizures.
A recent study published in Neurology found that patients undergoing combined heart bypass surgery and carotid endarterectomy experience a 38% higher chance of death or postoperative stroke compared to those who undergo coronary artery bypass surgery alone. The study suggests that the combined procedure may not provide additional benef...
A new study found a significant drop in patients undergoing carotid endarterectomy for inappropriate reasons. The study, published in Neurology, credits the decline to randomized controlled trials that clarified the surgery's proper use.
A study found that brain hemorrhages associated with warfarin increased by over tenfold in people over age 80, while the rate for all other populations quadrupled between 1988 and 1999. The increase was largely due to greater use of the drug, which is prescribed to prevent blood clots.
A study of 1032 women with chronic headaches found that those with migraines were four times more likely to report major depression symptoms. Chronic headache sufferers also experienced high levels of pain-related symptoms, including low energy and trouble sleeping.
A study published in Neurology found that zonisamide significantly improved tremors and dyskinesias in Parkinson disease patients. The medication was effective at 50mg/day, with a nearly 40% improvement in symptoms.
A study published in Neurology found that a gene variation linked to longevity also protects brain function in individuals over 90. Researchers analyzed 158 centenarians and found they had twice the likelihood of good brain function compared to those without the variant.
A study published in Neurology found that methamphetamine use is associated with an increased risk of major neck artery tears and stroke. The research reviewed two cases of women who experienced sudden speech difficulty and weakness after using the drug, resulting in severe strokes from carotid artery dissection.
Researchers used brain scans to study three women with sensory conversion disorder, also known as hysteria. The study found that stimulation of the numb hand or foot failed to activate the side of the brain that responds to touch, but did so when both limbs were stimulated.
A population-based study of 13,613 brain tumor cases in Sweden found that people with four or more siblings were twice as likely to develop a brain tumor. Children under 15 with three or more younger siblings had a two to fourfold increase in brain tumors compared to those with no siblings.
A year-long study found that enzyme replacement therapy reduced the risk of death in children with Pompe disease by 99 percent. The treatment, which involves replacing the deficient enzyme acid a-glucosidase, was shown to improve respiratory performance and reduce the need for ventilators.
A study published in Neurology found that people with Parkinson disease were more likely to make safety mistakes during a driving test than those without neurological disorders. The study involved an on-road driving test of participants with mild to moderate Parkinson disease and those of similar age without neurological disorders.
A study published in Neurology found that pregabalin significantly reduced severe pain and anxiety problems in patients with moderate to severe nerve pain after spinal cord injury. The medication was effective in relieving pain, improving sleep, and overall well-being.
A study found that enhanced caregiver support and counseling delayed nursing home placement by 1.5 years, improving caregivers' tolerance for patient behavior and increasing satisfaction with social support. This intervention could potentially save $90,000 per patient in nursing home care costs.
The new guideline aims to improve diagnosis and treatment of status epilepticus in children with epilepsy. It recommends considering anti-epileptic drug levels and performing an EEG to determine the cause of continuous seizures.
A study found that eating at least 2.8 servings of vegetables daily slows the rate of cognitive change in older adults by 40%, equivalent to about five years of younger age. Green leafy vegetables had the strongest association with slowing cognitive decline.
A recent study published in Neurology found that nearly 40% of children and teenagers with migraines no longer experience headaches 10 years later. Kids with a family history of migraines are more likely to still have migraines by adulthood.
Research found that Parkinson's disease patients developing impulse control disorders show increased rates of depression, appetite changes, and irritability compared to those without the disorder. The study identified nine patients with impulse control disorders, including pathological gambling, hypersexuality, and excessive shopping.