The study investigated LTF in OSA patients with hypoxic exposure using nasal CPAP. Hypoxia caused increased minute ventilation and decreased upper airway resistance, which persisted during the recovery period.
Researchers investigated how nasal volume affects nasal air-conditioning process when subjects lie face-up. The study found that increasing nasal mucosal temperature enhances nose's warming and humidifying abilities, but lying face-up reduces this ability.
Researchers quantified needle grasp by measuring pullout force, finding that two types of needle rotation had greater effects than no manipulation. These findings suggest a potential role for manual needle manipulation in acupuncture therapy.
Researchers investigated gas exchange between infants and their environment while sleeping facedown on soft bedding. They found that hypoxemia, not hypercarbia, is the more important factor contributing to SIDS deaths, suggesting a new approach to prevention.
Researchers developed a new technique, electrohydrodynamic atomization (EHDA), to produce monodisperse droplets of defined size for inhalation therapy. EHDA produced corticosteroid aerosols in quantities high enough for patient administration, showing promising results for more effective asthma treatment.
Researchers investigated the influence of gender on upper airway structure and function, finding no gender differences in resistance and Pcrit. These findings contradict previous assumptions and suggest a possible explanation for the male predominance of OSA, potentially related to neurochemical control or other factors.
A NASA review highlights known and potential gender differences in physiological responses to spaceflight, including cardiovascular and exercise physiology, barophysiology, and pharmacotherapeutics. The review also addresses reproductive issues such as menstrual function and endometriosis in space.
This year, APS awarded several prestigious lectureships to outstanding researchers in physiology. The award winners include Allen Cowley, Pontus Persson, Adrian Morrison, and Albert Bennett, who will present their research on various topics including genomics, cardiovascular function, biomedical ethics, and more.
The American Physiological Society has awarded over $160,000 to nine minority students pursuing PhDs in physiology. The one-year Porter Physiology Fellowships aim to increase underrepresented minority participation in the physiological sciences.
New research from the University of Pennsylvania suggests that physiology, particularly the vagus nerve, plays a role in gender differences in food choices. Studies found that women exhibited diminished vagally-mediated hormonal and gastric responses to food compared to men, which could explain why women tend to prefer healthier foods.
Female mice displayed higher sensitivity to amphetamines before and after puberty, differing from male mice who showed no changes, according to a study published by the American Physiological Society.
Researchers find that hormonal manipulation has no effect on virus responses in female rodents, suggesting genetic differences may be involved. In contrast, castrated male rats exhibit female-type responses to hantavirus infection.
Research by Harriet Hanlon explores how neural networks process language skills in boys and girls, finding differences in brain connectivity that impact reading abilities. The study suggests a balanced approach to language instruction can benefit both sexes.
Research suggests that estrogen replacement drugs can modify vein function in ways that increase the risk of venous thrombosis. Studies using adult female pigs found that hormone replacement therapies containing estradiol and SERMs altered cellular processes in veins, leading to changes in diameter, relaxation, and coagulation.
A study published by Harvard University Medical School found that during a woman's menstrual cycle, estrogen levels may shield them from cocaine's brain-altering effects. The findings suggest progesterone and testosterone enhance cocaine-induced vasoconstriction, while estrogen may blunt its vascular effects.
Estrogen controls lymphocyte formation and replenishment of the immune system by binding to hormone receptors found only in rare "precursors" within adult bone marrow. This discovery reveals that various kinds of stem cells may differ between fetal and adult life, protecting the fetus's immune system from estrogen-related compounds.
Researchers found significant susceptibility for thyroid autoimmune disorders and Type 1 diabetes mellitus associated with DQ2 alleles, primarily transmitted from fathers to affected daughters. Hormonal factors may also regulate this interaction, as observed in the transmission of disease to pre- and postpubertal individuals.
Researchers investigated how men and women's livers respond differently to chronic ethanol consumption. The study found that female rats' ability to activate protective genes was impaired compared to males, increasing their risk of liver damage when exposed to the same amount of alcohol.
Researchers found that men exhibited a decrease in coordination during exercise-induced hypoxia, whereas women showed an increase. Conversely, women had lower ventilatory responses to hypoxia compared to men.
The study found that estrogen receptors are more widely expressed in the brain during fetal and neonatal periods, influencing brain development. Antisense oligodeoxynucleotide treatment decreased brain estrogen receptor levels, leading to changes in ventilation and body growth in male and female rats.
This study reveals sex hormone effects on body fluid regulation and blood pressure, with men showing greater plasma AVP sensitivity to hypertonic saline infusion. This increased sensitivity is associated with higher systolic pressure, pulse pressure, cortisol levels, and sodium retention.
Research reveals women exhibit a greater decrease in arterial pressure during recovery, with reduced cardiac output and lesser increases in vascular resistance. Engaging light activity supports arterial pressure, regardless of gender.
Recent research highlights the significance of sodium-calcium exchange in various physiological processes, including vision, secretion, and cardiac contractility. The study also explores its potential applications in cancer therapy and heart function.
The Frontiers in Physiology program provides laboratory research experience to middle- and high-school-level teachers, learning effective education strategies and sharing experiences. Teachers participate in experiments, such as studying Siamese Fighting Fish behavior and exploring factors affecting blood flow and pressure.