The AUA Foundation has awarded the 2009 Astellas Rising Stars in Urology to William Roberts, MD and Edward Schaeffer, MD for their groundbreaking research projects on Benign Prostatic Hyperplasia and Phospholipase A2 signaling in prostate development. The award aims to support young urologists in pursuing careers in urologic research.
The Phase 3 IMPACT trial found that sipuleucel-T significantly prolonged overall survival by 4.1 months and improved three-year survival by 38 percent compared to placebo. This innovative immunotherapy reduced the risk of death by 22.5 percent.
The American Urological Association recommends individualized PSA testing for men 40 years or older with a life expectancy of at least 10 years. The test should be accompanied by a digital rectal exam to determine prostate cancer risk, which also considers family history and overall health.
The American Urological Association recommends PSA testing for men aged 40+, considering factors like family history and overall health. The new guidelines stress that prostate cancer is an individual decision, and the single standard should not apply to all men.
A new topical spray, PSD502, has been found to be an effective treatment for premature ejaculation, improving latency time from 0.6 minutes to 4 minutes in clinical trials. The spray selectively desensitizes penile skin without affecting sensation, making it a potentially attractive option for patients with this condition.
Two studies show that adult circumcision reduces the risk of contracting HIV and coital injuries, but does not affect sexual function. Circumcision removes skin surface susceptible to HIV infection, reducing the risk of transmission.
A study published by the American Urological Association found that well water intake is directly associated with bladder cancer incidence in women and mortality rates in both sexes. In contrast, exposure to solar UV radiation is inversely associated with bladder cancer incidence and mortality rates in both men and women. Cigarette smo...
Researchers found uterus sparing surgery to be an effective treatment option for women with pelvic organ prolapse, with 82.97% patient satisfaction rates. The study also showed minimal persisting symptoms, with sexual activity maintained in 95.5% of patients.
A study found that elderly patients experiencing nighttime urination had a higher mortality rate compared to those without nocturia. Researchers identified several factors associated with an increased risk of death, including age, diabetes, and hypertension.
A study reviewing 505 operative repairs found that prompt treatment improved survival rates, with extent of fibrosis being the only predictive factor for successful repair. Women with previous pregnancies showed significantly improved outcomes compared to first-time mothers.
Researchers have established criteria for reclassifying prostate cancer risk over time, allowing for more tailored treatment approaches. Patients with slow-growing cancer can benefit from reduced therapy burden, while those with more aggressive disease receive definitive care.
A study of 181 women found that increased sexual activity, recent alcohol consumption, and using sanitary napkins during menstruation were associated with an increased risk of developing their first urinary tract infection (UTI). Medical attention is crucial as UTIs can lead to kidney infections and sepsis.
A recent study found that generic substitutes for alpha blockers and 5-alpha reductase inhibitors are less effective in treating lower urinary tract symptoms (LUTS) than their branded counterparts. Men taking these generics experienced increased side effects, including dizziness, nasal congestion, and ejaculatory dysfunction.
Researchers confirmed that transplanting autologous muscle-derived cells into the bladder improves symptoms and quality of life in patients with stress urinary incontinence. The treatment has few side effects and significantly improved symptoms, with 76.5% of patients reporting a reduction in stress leaks at 12 months.
Researchers found that tadalafil improved detrusor pressure and bladder function in men with BPH-LUTS. The study also showed a significant reduction in obstructed patients after treatment with tadalafil.
A study published by the American Urological Association found that obesity is associated with a higher risk of urinary tract infections. Morbidly obese patients were most at risk, highlighting the importance of urologic care for individuals with elevated body mass indexes.
Researchers found that a three-year combination therapy of vitamin E, selenium, and soy did not prevent the progression from HGPIN to prostate cancer. The study results show that 26.4% of participants developed invasive prostate cancer, regardless of baseline characteristics.
Research suggests that diet soda's citrate and malate can inhibit calcium stone development, a known factor for kidney stones. Moderate consumption of diet soda may benefit patients with recurrent kidney stones.
Researchers investigated a novel nanoparticle platform that releases therapeutic levels of nitric oxide, which aids in erection biology. Five out of seven rats treated with these nanoparticles experienced positive effects on erectile response, resulting in visible erections.
A long-term clinical trial found that men who consumed pomegranate juice daily after treatment for localized prostate cancer experienced a significant increase in PSA doubling time and a decline in median PSA slope. This suggests that pomegranate juice may effectively slow the progression of post-treatment prostate cancer recurrence.
Long-term studies found that melamine consumption increases the risk of developing kidney stones in children, particularly between six months to 18 months old. Non-invasive treatment can effectively manage these complications with a high success rate.
The new guideline encourages healthy men to talk to their doctors about using 5-alpha reductase inhibitors (5-ARIs) to prevent prostate cancer, with a 25% relative risk reduction in most men. ASCO developed a Decision Aid Tool to help patients and families understand the risks and benefits of 5-ARIs.
Researchers presented innovative studies on sexual function, finding that statins can improve erectile function in men with metabolic syndrome. Additionally, new studies suggest that androgen therapy may restore sexual function faster post-prostatectomy than PDE 5 inhibitors.
Researchers developed nanoparticles consisting of metallic iron with a protective carbon coat that could serve as a safe and effective hyperthermia agent. The carbon coating prevented the iron from rusting, allowing heating at greater temperatures and reducing cytotoxic effects on normal cells.
A new study by the American Urological Association finds that elderly men experiencing moderate to severe lower urinary tract symptoms are significantly more likely to fall. Symptoms such as urinary urgency and nocturia increase the risk, highlighting the need for precautions to prevent falls.
A new study reveals that prostate cancer screening programs and access to urologists are significantly linked to reduced mortality rates. The research, presented at the AUA 2008 conference, found that higher urologist population densities and PSA screening rates correlate with lower mortality rates.
Researchers found that patients with high LDL cholesterol and increased serum cholesterol were up to 2.5 times more likely to experience a biochemical relapse after radical prostatectomy. Poor cholesterol management may affect not only prostate cancer risk but also biomedical recurrence after surgery.
The American Urological Association is calling for legislative action to cover erectile dysfunction therapy after radical prostatectomy. Researchers found that the costs of ED treatment are significantly less than breast reconstruction, but current insurance policies do not provide coverage for men with ED following prostate surgery.
Researchers found that African-American men with a family history of prostate cancer are unlikely to develop the disease if their baseline PSA level is below the age-specific median. In contrast, those with high baseline PSA levels are more likely to develop prostate cancer, even with other risk factors.
Researchers found that a single PSA reading taken at age 44-50 can predict prostate cancer diagnosis up to 30 years subsequently, even in men below age 40. The study suggests possible prolonged periods of prostate cancer pre-malignancy and the relationship between PSA and advanced cancer development.
Research suggests patients with metabolic syndrome disorders may be more likely to develop uric-acid stones. The study also found that patients presenting with uric acid stones could benefit from additional health screenings to identify related arteriosclerotic diseases.
Researchers from Tengion, Inc., present a new study suggesting that growing a replacement organ using the patient's own cells could be an effective and safe treatment option. The technique involves seeding bladder progenitor cells on a biodegradable scaffold, which can then be implanted into the patient.
Research finds higher serum levels of certain organochlorine compounds in mothers correlate with increased incidence of undescended testicles and hypospadias in sons. Maternal exposure to endocrine-disrupting chemicals may contribute to urologic conditions, highlighting the importance of regular well-baby checkups.
Two studies presented at AUA 2008 found that active surveillance is a viable option for low-risk prostate cancer patients. The studies highlighted the importance of reliable clinical predictors of disease progression and showed that endorectal MRI was the most reliable predictor of disease progression.
A new study by researchers at the University of California, San Francisco found that retired firefighters are at a higher risk of developing bladder cancer. The study, which tested 1,286 active and retired San Francisco firefighters, found two cases of transitional cell carcinoma (TCC) among the participants.
Childhood cancer survivors who received cyclophosphamide chemotherapy are at a higher risk of developing bladder cancer. Researchers found that the risk increases over time, with a significant increase after 20 years post-treatment.
Morbid obesity causes sexual dysfunction in men, but weight loss through gastric bypass surgery can normalize sexual function. The study shows that significant weight loss predicts improvement in all areas of the survey.
Men aged 75-80 with PSA levels below 3 ng/ml are unlikely to develop aggressive disease and may safely discontinue screening. The study's findings could lead to a reduction in unnecessary treatment for non-aggressive prostate cancers.
A study found that external-beam radiation therapy for localized prostate cancer increases the rate of secondary malignancies, including a 3.0-fold increase in bladder cancer, compared to radical prostatectomy. This predisposition is observed in lung-cancer resections and rectal cancer as well.
Researchers presented findings on Maxi-K gene therapy, showing it to be safe and restoring erectile function in men with moderate to severe ED. The treatment has been shown to enhance sexual behavior, including increases in partial and full erections and a two-fold increase in erection duration.
A new therapeutic vaccine has shown promising results in prolonging survival and improving the quality of life for men with metastatic prostate cancer. The adenovirus/PSA vaccine demonstrated strong immune responses to PSA, leading to improved patient outcomes.
In Iraq, penetrating bladder injuries from IEDs and bullets were common among civilians treated at Al Yarmouk Teaching Hospital. Most patients (78.1%) were injured by bullets, with associated bowel injury present in nearly all cases.
Researchers predict a rise in kidney stone disease due to global warming, with a potential cost of $1 billion annually by 2050. The southern US is expected to see an expansion of the
A study of 1,214 men prescribed cholesterol-lowering drugs found that PSA levels decreased after starting statins and correlated with LDL cholesterol decline. The results suggest a potential role for cholesterol in prostate cancer development and progression.
Researchers from Germany and Austria used muscle-derived stem cells to repair damaged sphincters. Patients showed significant improvements in continence, with some being completely continent after treatment.
The International Society for Sexual Medicine (ISSM) has established an evidence-based definition of premature ejaculation, which is characterized by early ejaculation and negative personal consequences. This new definition aims to improve diagnosis and treatment options for men suffering from premature ejaculation, allowing them to se...
A new study strengthens the association between exposure to Agent Orange and an increased risk of developing prostate cancer in aging Vietnam veterans. The study found that twice as many exposed men were diagnosed with prostate cancer, diagnosed at a younger age, and more likely to present with aggressive disease.
The AUA and EAU have released new guidelines for managing ureteral calculi, recommending updated treatment options such as ureteroscopy (URS) for all locations and sizes of stones. The guidelines also identify areas for future research to improve patient outcomes.
The American Urological Association has released new guidelines on managing non-muscle invasive bladder cancer, focusing on treatment outcomes and complications. The guidelines highlight the importance of accurate clinical staging and the need for further research to improve patient outcomes.
Studies suggest that phosphodiesterase inhibitors, commonly used for erectile dysfunction, can also alleviate lower urinary tract symptoms associated with benign prostatic hyperplasia. Researchers found improved scores on the International Index of Erectile Function and International Prostate Symptom Score, indicating potential benefit...