Researchers at ChristianaCare and the University of Delaware have identified five core biological rules that govern the structure and behavior of cells, potentially explaining how tissues stay organized. This discovery has significant implications for understanding tissue repair, birth defects, and cancer development.
A successful approach that eliminated Delaware's racial disparities in colorectal cancer can now be applied to breast cancer. The 'village' model focuses on building community partnerships and increasing access to care to reduce disparities.
A study found that alcohol withdrawal rates among hospitalized patients rose 34% during the COVID-19 pandemic. The study, conducted at ChristianaCare, suggests that hospital systems need to screen for and treat alcohol use withdrawal and refer patients for ongoing treatment.
Scientists at ChristianaCare's Gene Editing Institute are developing a novel gene therapy for inherited blood disorders like sickle cell disease using CRISPR technology. The team aims to identify genetic variations that affect treatment efficacy and create a tailored approach for personalized medicine.
Researchers at ChristianaCare's Helen F. Graham Cancer Center & Research Institute have identified a link between two crucial signaling pathways in the development and growth of colon cancer. The study found that an imbalance between WNT and RA signaling can lead to the evolution of colorectal cancer from stem cell populations.